DRUg Study
DRUg Study
DRUg Study
Tranexemic Acid Anticoagulants Oral : 1-1.5g (2-4x Treatment and Inhibits Hypersentivity Gastrointestinal Assess patient history
a day) prophylaxis of breakdown of disturbances Monitor anticoagulant cover
(Dostan, /antiplatelets hemmorrhage fibrin clots. It Active intravascular
Hemostan) TIV: slowly 0.5- clotting Hypotension Perform eye examination, liver
associated with acts primarily
1g (3x daily) excessive by blocking the function test, blood test
Severe renal Thrombotic
fibrinolysis. binding of Obtain prothrombin time
Infusion: rate at insufficiency Complication
Prophylaxis of plasminogen
25-50mg daily Reduced dosage for children and
hereditary and plasmin to Microscopic Disturbance of colour
angiodema fibrin; direct patients with renal impairment
hematuria vision associated with
inhibition of use, Advise to report visual
plasmin occurs
abnormalities to the physician
only to limitd
degree
Doxofylline Antiasthmatic Tab Adult 1 tab bid- Bronchial asthma Bronchodilator Acute MI, Nausea, vomiting, Use with caution in patients with
& COPD tid. Syr Childn >12 yr & pulmonary hypotension, lactation epigastric pain, hypoxemia, hyperthyroidism,
Ansimar 10 mL once-tid, <12 disease w/ spastic cephalalgia, liver disease, renal disease, in
those with history of peptic ulcer
yr 6-9 mg/kg bid. bronchial irritability,
and in elderly. Frequently,
component insomnia, patients with CHF have
May be taken with or tachycardia, markedly prolonged drug serum
without food extrasystole, levels following discontinuation
tachypnea, of Ansimar
hyperglycemia,
albuminuria,
Adverse reactions
may cause the
withdrawal from
treatment; a lower
dose rechallenge
may start only after
the advice of a
physician
Levodropropizin Antiasthmatic Adult & childn >12 Symptomatic Patients w/ GI effects, Tell to avoid driving or other
e & COPD yr 10 mL, >2 yr 1 treatment of excessive exhaustion, hazardous activities until
Preparations: mg/kg, 10-20 kg 3 cough discharge of faintness, stabilized on his medication.
Levofront mL, 20-30 kg 5 mL. mucus, w/ limited somnolence,
Antitussive Avoid alcohol and other CNS
All doses to be mucociliary clouding of depressants so not to enhance
taken tid function, severe consciousness, sedating property of the drug
liver dysfunction. numbness,
Should be taken on Pregnancy, dizziness, Advice to avoid smoking, smoke
an empty stomach lactation. Childn headache, filled environment
(Take between <24 mth palpitations.
meals.) Suggest sugarless lozenges to
Rarely, allergic
decrease throat irritation and
reactions cough
Generic & Dosage & Route of Contraindicatio
Classification Indication Action Adverse Reaction Nursing Responsibility
Brand Name Administration n
Erdosteine Cough & Cold Oral Erdosteine contains Active peptic Epigastralgia, Tell to avoid driving or other
Preparations Adult: 300 mg bid. As a mucolytic two sulfhydryl ulcer. nausea, vomiting, hazardous activities until
Ectrin cap, Ectrin Max duration: 10 in the treatment groups, which are loose stools, stabilized on his medication.
susp , Zertin Mucokinetics/E days. of respiratory freed after spasmodic colitis,
cap Zertin susp xpectorants Avoid alcohol and other CNS
tract disorders metabolic headache. depressants so not to enhance
and productive transformation in sedating property of the drug
cough the liver. The
liberated sulfhydryl Advice to avoid smoking, smoke
groups break the filled environment
disulphide bonds,
which hold the
glycoprotein fibres
of mucus together.
This makes the
bronchial secretions
more fluid and
enhances
elimination
Generic & Classificatio Dosage & Route of Indication Action Contraindication Adverse Reaction Nursing
Brand Name n Administration Responsibility
Hydrocortisone Oral: 5-30mg (2x-4x Tuberculous Glucocortocoid with Systemic fungal Depression, Teach all aspect of
Adrenocortic a day meningitis, anti-inflammatory infection, IM use in Flushing, sweating, drug usage, the
Cortizan, ostertoid trichinosis effect because of its idiopathic headache, mood danger of stopping
Efficort,Pharma IM/IV: 100-250mg abruptly and signs
hormones with ability to inhibit thrombocytopenic changes,
cort,Solu-Cortef (succinate) then 50- of early renal
neurologic or prostaglandin purpura; hypertension, insufficiency :
100mg Im as myocardial synthesis, inhibit administration of circulatory collapse, (weakness, joint
needed; Im/Iv 15- involment, macrophages, live virus vaccines thrombophlebitis, pains, fever
240mg every 12 hrs dermatologic leucocytes and in patients receiving embolism, anorexia, nausea, d
disease, fibroblast at sites of immunosuppressive tachycardia, edema, yspnea, fainting)
Give medication
respiratory inflammation, corticoid doses; fungal infections ,
with food Advise to
disease phagocytosis and pyschosis; acute increase intraocular
wear/carry
lysosomal enzyme glomerulonephritis; pressure, blurred emergency ID as
relese. It can also amebiasis; vision, diarrhea, steroid user
cause reversal of nonasthmatic nausea, abdominal, Instruct to notify
increased capillary bronchial disease; distention, poor physician of
permeability children <2yrs, wound healing, decreased
AIDS, TB. weakness therapeutic
response for
proper dose
adjustment
Instruct to monitor
and report signs
and symptoms of
infection
Generic/ Classification Indication Mechanism of Contradiction Side Effects Nursing Responsibilities
Trade Name Action
Amikacin Anti-infectives Treatment of Inhibits proyein Contraindicated in EENT: ototoxicity Assess patient for infection (vital
serious gram- synthesis in patients who has (vestibular and signs, appearance of wound, sputum, urine
(amikin) negative bacilliary bacterial at level previous cochlear)GU:nephrotoxici and stool; WBC) at beginning and
infections caused of 30s ribosomes. hypersensitivity to ty throughout therapy.
Dosage: Obtain specimens for culture and
by staphylococci the drug.
MS:muscle paralysis sensitivity before initiating therapy.
250 mg when penicillins
Monitor intake and output and daily
or ather less toxic weight to assess hydration status and renal
Therapeutic MISC:
Frequency: drugs are function.
effect:
contraindicated. hypersensitivity reactions Assess patient for signs of
Every 6 hours bactericidal
superinfection (fever, upper respiratory
action. infection, increasing malaise and diarrhea)
Monitor blood levels periodically
during therapy for toxicity and overdose.
Generic / Trade Dosage / Classification Indication Contra- Indication Side Effects Nursing Responsibilities
Name Frequency
Paradoxiacal
Combivent Every 6 hours Bronchodila Chronic obstructive Difficult urination bronchospasm 1. Determine the
Nebulizer tor pulmonary disorder Glaucoma Cardiovascular effect history for allergies.
Heart rhythm problem Coronary 2. Educate the client
Hypertension not to store it near
insufficiency
Problem with blood
Cardiac arrhythmias heat or open flame
circulation to the heart Hypertension 3. Tell the client to
Hypersensitive to soya Hypersensitive avoid spraying it to
lecithin reaction the eye.
Urticania 4. Inform the client
Anginoedema that it should not be
Rashes
used more
Anaphylaxis-
frequently than
Oropharyngeal edema
recommendation.
5. Tell the client that
use of other inhaler
needs a medical
advice.