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General Characteristics

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General characteristics

the term carbohydrate is derived from the


french: hydrate de carbone
compounds composed of C, H, and O
(CH
2
O)
n
when n = 5 then C
5
H
10

CARBOHYDRATES
Living things use carbohydrates as a
key source of
ENERGY
!
Plants use carbohydrates for structure
(
CELLULOSE
)
include sugars and complex carbohydrates
(starches)
contain the elements carbon, hydrogen,

General characteristics
Most carbohydrates are found naturally in
bound form rather than as simple sugars
Polysaccharides (starch, cellulose, inulin, gums)
Glycoproteins and proteoglycans (hormones, blood group
substances, antibodies)
Glycolipids (cerebrosides, gangliosides)
Glycosides
Mucopolysaccharides (hyaluronic acid)
Nucleic acids

Functions

sources of energy
intermediates in the biosynthesis of other
basic biochemical entities (fats and proteins)
associated with other entities in vitamins and
antibiotics
form structural tissues in plants and in
microorganisms (cellulose)
participate in biological transport, cell-cell
recognition, activation of growth factors, modul
the immune system

Classification of
carbohydrates
Monosaccharides (monoses or glycoses)
Trioses, tetroses, pentoses, hexoses

Oligosaccharides

Di, tri, tetra, penta, up to 9 or 10


Most important are the disaccharides

Polysaccharides

Complex carbohydrates

Carbohydrates

have the following basic composition:

Monosaccharides
- simple sugars with multiple OH groups. Based
on number of carbons (3, 4, 5, 6), a
monosaccharide is a
triose
,
tetrose
,
pentose
or

Monosaccharides
also known as simple sugars
classified by the number of carbons
most (99%) are straight chain compounds
sugars have the ending
ose
(glucose, galactose, ribose, lactose, etc)

Monosaccharides
Aldoses
(e.g., glucose) have an
aldehyde
group at one end.

Ketoses
(e.g., fructose) have a
keto
group, usually at C2.

Monosaccharides (simple sugars)


all have the formula C
6
H
12
O
6
all have a single ring structure
(glucose is an example)

Pentoses and
hexoses can
cyclize
as the ketone
or aldehyde
reacts with a distal
OH.

Cyclization of glucose produces a new


asymmetric center
at
C1
. The 2 stereoisomers are called
isomers
,

Glycosidic Bonds

The C1 hydroxyl and a hydroxyl of


another sugar or some other compound ca
together, splitting out water to form a
glycosidic bond:
H
+
HO
-R'

Disaccharides (double sugars)


all have the formula C
12
H
22
O
11
sucrose (table sugar) is an example

Disaccharides

:
Maltose
, a cleavage product of starch (e.g.,
amylose), is a disaccharide with an

(1
4)
glycosidic
link between C1 - C4 OH of 2 glucoses.
It is the

anomer (C1 OH points down).

Other
disaccharides
include:
Sucrose
, common table sugar, has a glycosidic bond
linking
glucose
&
fructose
.
Lactose
, milk sugar, is composed of
galactose
&
glucose

Polysaccharides
Formed of three or more simple sugar
units
Glycogen - animal starch stored in liver
& muscles
Cellulose - indigestible in humans forms cell walls
Starches - used as energy storage

Polysaccharides

:
Plants
store glucose as
amylose
or
starch
Amylose
is a glucose polymer with

(1

Cellulose
, a major constituent of
plant cell walls
, consists of long linear chains of glucose with

(1
4)
linkages.

Dehydration Synthesis
Combining simple molecules to form a
more complex one with the
removal of water
ex. monosaccharide + monosaccharide
----> disaccharide + water
(C
6
H
12
O
6

Hydrolysis
Addition of
WATER
to a compound to
SPLIT
it into smaller subunits
(also called chemical digestion)
ex. disaccharide + H
2
O ---> monosaccharide +
monosaccharide

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