Lab Manager Magazine 2015
Lab Manager Magazine 2015
Lab Manager Magazine 2015
Volume 10 Number 3
LabManager.com
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contents
April 2015
LabManager.com
10
18
24
40
feature
10
technology
business management
18
32
36
Lab managers who must cut costs while procuring high-quality and
low-risk equipment and maintenance services use the procurement
process to set the parameters of quality and risk. Lina Genovesi
24
Lab Manager
April 2015
Virtual Reality
Communicating the nal design of a laboratory to the principal
investigators and their research teams can be challenging. Visualization software makes things easier. Chuck Yocum
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April 2015
52
48
54
Trevor Henderson
Mike May
58
64
Tanuja Koppal
Mike May
66
Trevor Henderson
Angelo DePalma
72
70
Nitrogen Evaporators
ELN Survey
Find out what our readers use their
ELNs for and more in these results.
Angelo DePalma
Titrators
Trevor Henderson
74
Mike May
in every issue
28
30
Science Matters
76
How it Works
Pressure-Based Microplate Volume Measurement
78
Technology News
The latest equipment, instruments, and system introductions to the laboratory market.
89
89
Advertisers Index
90
Lab Manager
April 2015
LabManager.com
editors note
Also a fit for the April issue is the topic of millennials, that ideological
and community-centric cohort most likely to be leading your labs
sustainability efforts. In just five short years, millennials will represent
44 percent of the U.S. workforce. Five years after that, that number will
be 75 percent!, reminds Mark Lanfear in his Science Matters column
(page 30). In addition to their communication and teamwork skills, their
tolerance of diversity in the workplace, and their easy accommodation
of change, it is their comfort with technology that makes them so perfectly suited to todays lab. (Millennials in the Lab, page 24).
As we learn in this months Ask the Expert article on trends in lab
automation (page 56), that comfort with technology will only serve
them better as changes in informatics and communication rely more
heavily on portable notepads and software to control instruments inside
and outside the lab. Next months cover story on laboratory gadgets and
apps will explore this in greater detail.
In the meantime, heres to Spring and all things green.
Best,
Pamela Ahlberg
Editor-in-Chief
editor-in-chief
account managers
Pamela Ahlberg
Greg Brewer
June Kafato
president
pam@labmanager.com
gregb@labmanager.com
International
Bob Kafato
973.729.6538
888.781.0328 x241
junek@labmanager.com
bobk@labmanager.com
705.812.2332
888.781.0328 x223
associate editor
senior designer
Rachel Muenz
Danielle Gibbons
Larry Frey
managing partner
rachelm@labmanager.com
danielleg@labmanager.com
Mario Di Ubaldi
888.781.0328 x233
888.781.0328 x237
larry@labmanager.com
mariod@labmanager.com
845.735.5548
203.227.1390
technology editor
business coordinator
Trevor Henderson
Andrea Cole
Alyssa Moore
general manager
thenderson@labmanager.com
andreac@labmanager.com
Mid-Atlantic
Ken Piech
888.781.0328 x291
888.781.0328 x296
amoore@labmanager.com
kenp@labmanager.com
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888.781.0328 x226
contributors
list rental
Jen FellingStatlistics
Stephanie McFadden
publisher
203.778.8700
Northeast
Edward Neeb
smcfadden@labmanager.com
edwardn@labmanager.com
888.781.0328 x300
860.350.2761
Lab Manager
April 2015
info@labmanager.com
LabManager.com
ith freezers and fume hoods running nonstop, its no surprise that lab facilities hog
more resources than do most other workspaces. Labs consume about four to ten times more energy, water, and other materials than do offices and classrooms. The labs at the University of Colorado Boulder
(CU-Boulder) occupied 20 percent of the total square
footage on campus during 2010-2012, but accounted for
43 percent of its total energy consumption.
In response, academic institutions have been increasingly nudging their scientists and researchers toward
greater resource conservation and promoting sustainability via green labs. The goal of this approach is to save
energy, water, and materials and reduce waste, especially
toxic and hazardous types. Kathryn Ramirez-Aguilar,
PhD, green labs program manager at CU-Boulder, says a
green lab is one that takes action where it can to minimize the use of resources needed for its research.
Dr. Ramirez-Aguilar says energy usage and savings vary
across different labs. CU-Boulders green labs program,
which started in 2009, works closely with the universitys
400 different labs to help them acquire equipment and
appliances like vacuum pumps and refrigerators that are
energy efficient but still able to meet their needs. Labs that
purchase energy-efficient equipment may be eligible to
receive financial incentives, she says.
Turning to the key driving forces behind these efforts,
Ramirez-Aguilar says that while saving money through
the efficient use of our resources is certainly a benefit,
reducing the footprint of laboratories with respect to
energy, water, and other resources is a major commit-
10
Lab Manager
April 2015
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6. Two students testing old freezers for energy savings documentationone freezer is 15 years old, the chest freezer is about
30 to 40 years old 7. In 4 to 6 months it pays off to give away
outlet timers for laboratory equipment that is not practical
to turn off late at night, or on very early in the morning. 8. A
student installing outlet timers for equipment that needs to be
stable first thing in the morning.
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Doyle says that there are about 1,000 freezers in the labs at UC Davis, each of which uses
more electricity than does a house. He describes
the operation of freezers at temperatures such as
-80 degrees Celsius as overkill because there is
rarely a need to operate in such cold conditions.
This is a push by industry, not science, he says.
In the future, he would like to see better dry
storage of samples. I am hoping that cold storage will be managed at [the] institutional level.
He says that is difficult because individual
scientists now take responsibility for cold storage and for the management of inventory and
other detailsa rather ambitious undertaking.
Doyle is optimistic that the ventilation of lab
buildings will get a lot smarter in the future
and that there will be elegant breakthroughs in
building automation, all of which will advance
sustainability objectives.
Bernard Tulsi is a freelance writer based in Newark,
Delaware. He may be contacted by email at btulsi@
comcast.net or by phone at 302-266-6420.
High throughput at a
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business management
THE PROCUREMENT
PROCESS
RFPS, MAINTENANCE CONTRACTS, SUPPLIER
AUDITING, AND MORE by Lina Genovesi
Lab Manager
April 2015
Selecting suppliers
Following the bids and the responses to the RFP, suppliers of the equipment and maintenance services are
selected, based on the information gathered in the RFP.
Daniel J. Scungio, laboratory safety officer at Sentara
Healthcare, believes equipment maintenance is important to maximize quality and minimize risk. Equipment
maintenance is an essential component of quality in not
only ensuring good working equipment, but also in ensuring that the instrument is consistently compliant with
regulations, which minimizes the risk.
Labs have several options for equipment maintenance.
These options include working with in-house teams,
third-party service providers, original equipment manufacturers (OEMs), and multiservice providers.
In-house teams are generally composed of maintenance and service teams. In some instances, members of
maintenance teams are also trained to service a piece of
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There are pros and cons associated with each option for equipment maintenance.
Whether a lab relies on its in-house team, a third-party provider, an
OEM, or a multiservice provider, quality is measured by the increase or decrease in the level of risk, which is inherent in maintaining the equipment
to meet the demands of the lab, says Scungio.
Maintaining in-house teams requires a huge investment on staffing,
training, infrastructure, and inventory management, and is likely to make
operations dependent on the allocated resources for maintenance. In a continuously changing technological environment, the efficiency and technical
expertise of the team is always a concern and any resource loss would add
to the risk. These are the reasons that lab managers and their procurement
departments are moving toward outsourcing to an OEM, a third-party
service provider, or a multiservice provider either as a first option or as a
stopgap measure in the event of any failure of the in-house team.
Third-party service providers do not have the large overheads of OEMs,
are able to provide services at a cost savings, and can be useful in times of a
sudden equipment breakdown as their response time is quick, even though
their inability to maintain quality due to technological change and associated risks may be trade-off points.
For small labs with a limited number and limited types of equipment,
OEM service teams are a favorable option. Whether the lab is small or large,
an OEM guarantees a qualitative low risk due to potentially uninterrupted
laboratory functioning. An OEM also increases the total cost of ownership
of a piece of equipment due to comparatively costly spare parts and labor
and high administration costs.
In terms of the quality and precision of the service, a multi-vendor
service provider is comparable to an OEM. A multi-vendor service provider can handle equipment supplied by other vendors and supports on-site
services. Opting to use a multiservice provider decreases the total cost of
equipment ownership by streamlining the service processes, increasing
operational efficiency, and reducing the expenses while minimizing the risk
involved. For large labs, a multi-vendor service provider offers an optimum
solution for asset management, and for very critical equipment, a multiservice provider can ensure that equipment uptime is maintained.
Postprocurement
Postprocurement, lab managers must monitor supplier performance for continual improvement and to ensure adherence to the quality and risk criteria.
The use of a continual improvement philosophy is fast becoming a requirement to keep costs down and ensure that quality is at a maximum and risk is at
a minimum, says Scungio. Continual improvement is even more important
when equipment and maintenance services are used in the context of patient
services where health and safety issues are important considerations.
Below are tips for monitoring supplier performance.
Auditing
Conduct a meeting with the supplier at the beginning of the
equipment maintenance program.
3/19/2015 5:51:08 PM
22
Lab Manager
April 2015
LabManager.com
business management
Get to Know
Metrohm
Titration
Ion Chromatography
Request that a supplier take corrective actions to develop and implement mitigation plans for the risks identified during risk assessment
Monitor the status of any risk mitigation plan during future audits
Supplier auditing must be done on a regular basis, and in the event of risk
identification, the frequency of supplier auditing and monitoring must be
based on the results of any risk assessment.
Going forward
Companies are using procurement and sourcing functions to differentiate
themselves from competitors and optimize key business processes.7 With the
pressure to cut costs on the rise, it is incumbent on company management to
empower and support lab managers to make the best possible procurement
decisions, thereby maximizing their quality and minimizing the risks inherent in purchasing equipment and equipment maintenance services.
Electrochemistry
Spectroscopy
References:
1. http://www.atkearney.com/procurement/assessment-of-excellence-in-procurement-study/full-report
Laboratory
Process
2. www.perkinelmer.com/onesource/
3. www.thermofisher.com/en/about-us/unity-lab-services.html
Find out more at
www.metrohmusa.com/technology
4. http://crosslab.chem.agilent.com/services.html
5. http://www.gelifesciences.com/webapp/wcs/stores/servlet/catalog/en/
GELifeSciences-si/service-and-support/lab-optimization-solutions/
6. http://www.gelifesciences.com/webapp/wcs/stores/servlet/catalog/en/GELifeSciences/service-and-support/multivendor-life-cycle-asset-management/
7. http://www.atkearneypas.com/solutions/spend-analysis.html
www.metrohm.com
April 2015
Lab Manager
23
MILLENNIALS
IN THE LAB
A FIT FOR THE FUTURE
By Rachel Muenz
24
Lab Manager
April 2015
Managing millennials
Longoria and Blackburn say there are some things they
do differently with millennials, but as far as managing this
particular group is concerned, overall their management
style is pretty similar for all groups in their labs. Longorias
organization took proactive steps to prepare for the expected retirement of baby boomers in her lab, putting management through generational training because they knew
many of the vacancies would be filled by millennials.
Understanding whats important to them is critical for
continued success, she says, adding that her lab has recently had a second batch of employees retire, meaning
even more millennials are expected to come on board.
Ive been doing what Im doing for 21 years, so I would
be considered a Gen Xer, but Im kind of in the middle,
where I understand baby boomers but I also understand
the millennial thought process. I think I have a great advantage because I have a lot of nieces and nephews who
are the same age as some of these millennials.
She adds that taking the time to listen to millennials is
important, along with providing feedback and recognition, to get the best work out of them. For example, her
LabManager.com
In her case, Longorias love of music is something that helps her connect with staff members of all ages, because her taste is so varied.
I connect with pretty much all my staff because of music, she says, adding that the team
concept her lab uses is a good way to integrate
all kinds of diversity in the workplace. In a
team, you include all the team members, no
matter what generation they are in and no matter whats important to them. You have to respect the differences. Accepting diverse needs,
wants and expectations is pretty challenging,
but if you understand that at the beginning its
not so painful in the end. I think just having a
positive attitude and putting positive energy
toward any subject matter or goal is critical.
As for millennials being branded as lazy, Blackburn says that comes from
a misunderstanding as well, since in her experience millennials just seek
easier ways of getting things done.
Longoria admits that she did have an issue with that perception of entitlement when she first started working with millennials, until she gained
more understanding through generational training.
I was not used to people expecting something when they havent proven
themselves, she says. Im from a generation where you prove yourself and
then you expect a reward. When somebody today graduates with a degree,
that degree says a lot more to them than it does to somebody who has experience and a degree. Its very difficult for me to advance workers when they
havent proven themselves. Im still very big on performance. Degrees are
greata masters degree is even betterbut that doesnt necessarily mean
that theyre going to be the greatest employees.
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creating for your company and yourself ? It could be a lot, yet no one will
ever mention anything to you about it.
Yes, the meeting room should be
clean, but how about the lobby, parking lots, and restroom? What type of
impression are you creating for your
lab, your team, and yourself if they
are not looking great?
28
Lab Manager
April 2015
LabManager.com
science matters
TITLE XXXXXXXXXXXXX
LATEST TRENDS SHAPING THE SCIENTIFIC WORKFORCE
MANAGING MILLENNIALS
ITS THEIR GENERATION NOW
By Mark A. Lanfear
Lab Manager
April 2015
Leadership Deficit. It provides an insightful perspective on understanding millennials; it also suggests strategies for engaging them. The book
also compares and contrasts how
the different generations view their
work-life balance and how organizations must adapt their recruiting and
retention strategies to deal with this
inevitable demographic shift.
While Gen Now is arguably the
best-educated generation in history,
after living through the turmoil of the
2008 U.S. recession many are not expecting to have traditional careers, but
rather they are planning to have series
of professional experiences. This is a
significant departure from the ideal career pursuits of previous generations.
Millennials also tend to be team-driven
and inclusive, and they have a significant
appetite for change. They like constant
feedback, which they enjoy personally
and professionally while engaging their
social media networks. And although
baby boomers live to work, Gen Now
works to live. They are inspired by the
value they add to their work and seek
meaningful assignments over the myriad other attraction techniques offered
by employers. Many are frustrated by
traditional office hierarchies, cube life,
and the vague notion of a 9-to-5 job.
Their sense of loyalty to an employer
is far different from what baby boomer
and Gen Xer managers might project
onto them. Loyalty for Gen Now is to
their professions and networks, rather
than to their employers. Its quite a big
shift.
LabManager.com
science matters
One things for sure: Youd never treat a complex biosimilar product the same way youd treat a generic drug. And
youll absolutely want to manage Gen Now talent in ways
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Lab Manager
April 2015
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Flasks
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Summary
Physically walk around the lab with motion-tracking integration software at the CD stage of design
Visualize multiple design alternates (equipment, adjacencies, exteriors, floor plans, lighting
schemes, interior design layouts, etc.) in real time
Add/delete customizable 3-D props (equipment,
outlets, specialty gas sources, exhaust points,
avatars, etc.) within your environment instantly
Mock up large spaces such as collaborativeinteractive zones, atrium, etc.
Collaborate with multiple users in single or
multiple settings
Use existing 3-D models created in major architectural design programs such as Revit, AutoCAD, 3D
Studio Max, SketchUp, and many others
www.genevac.com
technology
36
Lab Manager
April 2015
Echoing the attributes of a physical social group, UDPICS forms virtual social networks modeling traditional
social hierarchy. Privileges conceptually similar to those
defining relationships in other social groups are provided
by permissions in UDPICS and determine access to data,
functions, and requests. These are assigned according to
the role or needs of the user; each successive role is associated with more permissions. These roles reflect those
of social groups; namely, initiator-contributor, procedural
technician, orienter, integrator, opinion giver and opinion
seeker, and information giver and information seeker. This
integration of defined social hierarchy within UDPICS
promotes a transparent relationship among users that
leads to scaling of virtual collaborative networks.
The centralization of information related to a patient
within UDPICS provides a foundation that encourages discussion of perspectives and fosters creativity
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We started with the form factor: how to gain a large work area with a limited
footprint. As with most great innovations the solution was simple we removed
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from the ground up we added enhanced remote monitoring capabilities,
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Lab Manager
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protection
With Thermo Scientific biological safety cabinets, the certified performance and
protection you get on Day 1 stays with you every day. Not true with ordinary cabinets.
The difference is our design: SmartFlow technology features dual-DC motors to
automatically balance the cabinet inflow and downflow air velocities in real time even
as the filters load. That means exceptional user and sample protection you never have
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Due to DC motors, Heraguard ECO clean
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Based on data from internal testing and The
University of Michigan field study, published
in American Biotechnology Laboratory
IAQ commissioning
Because of the time and expense of conducting a building flush out, we prefer the second option of IAQ commissioning. Performing baseline indoor air quality testing
demonstrates that certain common indicators do not exceed
recommended maximum concentrations. Following our
protocol, the indoor air is sampled for formaldehyde, total
particulates, total VOCs, carbon dioxide, carbon monoxide, relative humidity and 4-phenylcyclohexene (4-PCH).
Sampling for 4-PCH is required only if carpets and fabrics
containing styrene butadiene rubber latex backing were
installed as part of the base building systems.
In order to collect accurate and representative data,
the testing must be conducted prior to occupancy and
during normal occupancy hours. All HVAC systems
42
Lab Manager
April 2015
must be operated at the normal daily settings (including the minimum outside airflow rate) during testing.
All interior finishes must be installed. The number of
sampling locations depends on the building size and
the number of separate ventilation systems. Sampling
should be done for each portion of the building served
by a separate HVAC system and include at least one
location for every 25,000 ft2. More samples or sampling
locations may be required to assess the area with confidence. Finally, all samples should be collected from
between three and six feet above the floor, the area representing the occupant breathing zone. The table below
provides the maximum allowable concentrations for the
recommended commissioning parameters.
PARAMETER
MAXIMUM ALLOWABLE
CONCENTRATIONS
RATIONALE
Formaldehyde
Particulates
(PM 10)
VOCs
500 ug/M3
Carbon Dioxide
Carbon Monoxide
4.0 ppm
Relative Humidity
<60%
4-PCH
6.5 ug/M3
References
1. LEED Reference Guide for Green Building Design and
Construction. U.S. Green Building Council. Washington,
DC. 2009. http://www.usgbc.org/resources/leed-reference-guide-green-building-design-and-construction
LabManager.com
2. LEED 2009 for New Construction and Major Renovations Rating System. Version
2009. U.S. Green Building Council. Washington, DC. April 2013. http://
www.usgbc.org/resources/leed-new-construction-v2009-current-version
3. Ventilation for Acceptable Indoor Air Quality, American Society for Heating,
Refrigerating and Air-Conditioning Engineers. Atlanta, GA. 2013. https://
www.ashrae.org/resources--publications/bookstore/standards-62-1--62-2
Additional resources
Indoor Air Quality. U.S. Environmental Protection Agency. Washington, DC.
December 2008. http://www.epa.gov/iaq/
Indoor Environmental Quality. Centers for Disease Control and Prevention,
National Institute for Occupational Safety and Health. Atlanta, GA. June
2013. http://www.cdc.gov/niosh/topics/indoorenv/
Vince McLeod is the founder and senior member of the Safety Guys and an industrial hygienist certified by the American Board of Industrial Hygiene. He currently serves
as the senior industrial hygienist in the University of Floridas Environmental Health
and Safety Division. He has 27 years of occupational health and safety experience at
the University of Florida, and he specializes in conducting exposure assessments and
health hazard evaluations for the universitys 3,000-plus research laboratories.
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Harm Moes is technical support engineer at SGS in the Netherlands. Mr. Moes
has 13 years of experience in analytical instrumentation and held several
technical positions with an analytical instrument supplier before joining SGS. At
SGS, he provides technical support to the SGS oil, gas, and chemical labs in the
Netherlands. That includes implementation and validation of new instrumentation,
techniques, and methods, and instruction and training of laboratory personnel.
Harm Moes
laboratory do?
44
Lab Manager
by Rachel Muenz
April 2015
A: First of all, you need sufficient separation of the components youre interested
in, so it depends on whether youre doing
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The more
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STARLINE Plug-In
Raceway looks.
Sure, it may look like other raceway
products. But STARLINE Plug-In
Raceway has the unique ability to
add or relocate plug-in modules
anywhere on the raceway quickly and
easily, eliminating panel boards and
the associated costs of reconfiguring
circuits, receptacles and wiring. To
learn how we can meet the power
distribution needs of universities,
labs and research environments,
visit StarlinePower.com.
INSIGHTS
Lab Manager
April 2015
ADDING INTELLIGENCE
Ayasdis Topological Data Analysis (TDA) reveals hidden relationships in complicated data sets, which can be used to develop
new treatments. (Image courtesy of Ayasdi.)
SAMPLING SHAPES
TEXT TO TREATMENT
Novus
Lab Instrumentation
text mining in the pharmaceutical industry. This included chemical analysis, like mining text for different names
used for the same formula.
Now he uses some similar thinking with IBM Watson,
which is the computer that defeated two former Jeopardy!
champions in 2011. Now IBM applies Watson to health
care, among other things. For example, in collaboration
with Baylor College of Medicine in Houston, Texas,
IBM aimed Watson at molecular biology. Spangler says,
We spent a few years training Watson to understand biologyto think in terms of the physical objects, like the
chemicals, and targets, like proteins in a cell. He adds,
We also taught it to understand the disease or condition
that you are trying to alleviate with the drug. In addition, this technology can help pharmaceutical scientists
pick the best drug targets.
In particular, scientists can use big data for drug discovery with IBMs Watson Discovery Advisor. This is
available through a browser as software as a service. So
anyone can use it to test hypotheses virtually, all based
on the data in millions of published papers. As Spangler
says, Watson digests way more information than a human expert can, and it can help them be better scientists
and make better predictions moving forward.
Scott Spangler, principal data scientist, IBM Watson Innovations, demonstrates how IBM Watson cognitive technology
can visually display connections in scientific literature and drug
information. Here, Watson displays protein pathways that can
help researchers accelerate scientific breakthroughs by spotting
linkages that were previously undetected. (Image courtesy of Jon
Simon/Feature Photo Service for IBM)
To take on these challenges with computation, scientists
need large datasets. As Spangler says, Biology is very
hard and very statistical. He adds, You cant think of it
like computer science, with a direct cause and effect. It
doesnt work that way. A molecular process that works
one way now could work differently an hour from now
or in a different person. This creates very noisy data.
Thats exactly what Watson tackles. It tries to quantify confidence. As Spangler asks, How certain are we of various
conclusions? Where can we find corroborating evidence?
50
Lab Manager
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LabManager.com
In all cases, big data is of use only when you know what to do with it. For
example, Jordan Stockton, director of marketing for enterprise informatics
at Illumina in San Diego, California, says, Winnowing the many pieces
down to the useful ones gets underemphasized.
That step requires software that many people can use. For example, Illuminas NextBio lets a scientist use genomic data at nearly any stage of drug
discovery or development. For instance, this platform provides genomic data
from cell lines that can be used to study specific drug targets.
Tools like NextBio and others mentioned here will become increasingly
valuable in drug discovery. As Naomi OGrady, marketing manager, oncology at Illumina, explains, The discovery-to-drug process is like a funnel.
That is, researchers tend to work on more focused datasets as the process
moves forward. Nonetheless, OGrady points out, But even at the bottom
end of the funnel, the amount of information being considered is getting
bigger. More information is being considered at every step.
Consequently, pharmaceutical scientists will need ever more data to make
the most of the existing knowledge base. They will also need sophisticated
tools that pick out the key data and the interconnections. Only then can
large datasets turn drug discovery into an efficient and effective process.
Mike May is a freelance writer and editor living in Ohio. You may reach him at
mike@techtyper.com.
The Mini-Beadbeater-24
disrupts microorganisms and
tissue preparations with better
than 95 percent efficiency.
Nucleic acids and proteins are
isolated with the highest possible
yields. Cells are disrupted quickly
and safely in the sealed 2 ml
microvials containing small beads.
No cleaning between samples
is required. The apparatus has a
small footprint and is essentially
maintenance free.
800-617-3363
www.biospec.com
TITRATORS
E
IC
GOOD LABO
RA
GO
OD
D
O
Compliance
PRACTICE
GO
RY
TO
52
Lab Manager
April 2015
LabManager.com
Instrument tips
Good compliance begins with good recordkeeping and good
instrumentation, says John D. MacFarlane, applications
support specialist at JM Science (Grand Island, NY). The
company is the exclusive importer and distributor of the
AQUACOUNTER titrator line manufactured by Hiranuma
(Ibaraki, Japan). Kenichi Hiranuma, president, offers the
following instrument-related tips to facilitate GLP compliance:
Electrodes: Record electrode(s) type, starting date of use,
and manufacturer data such as lot number. These data
provide reference points for documenting subsequent
maintenance and testing activities.
Burette: Record the starting service date and total dispensed
quantities. For reliability checks, fill burettes with pure
lab water and dispense quantitatively into an appropriate
tared weighing vessel. Confirm repeatability and accuracy
by measuring dispensed weight. Hiranuma recommends
following burette practices outlined in JIS K 0050:2011,
General Rules for Chemical Analysis from the Japanese Industrial
Standards Committee. Other official or unofficial standards
are acceptable as well. Also, confirm operation of the burette
sample changer.
Calibration and error history: Saving past pH calibration
data reveals the point in time when electrode malfunction
began. Hiranuma advises labs to maintain a daily graph of
calibration and error events.
FOR ADDITIONAL RESOURCES ON TITRATORS, INCLUDING USEFUL ARTICLES AND A LIST OF MANUFACTURERS,
VISIT WWW.LABMANAGER.COM/TITRATORS
April 2015
Lab Manager
53
survey says
TOC ANALYZER?
91%
Portable
14%
7%
Online
Total Organic Carbon (TOC) analyzers are a mainstay of environmental and quality control
chemistry. TOC, a crucial metric in many processes, may arise from a combination of living or
dead organisms or chemical contamination. Its measurement can serve as a surrogate for more
difcult measurements or a screen for further analysis.
TOP 5 QUESTIONS
67%
Direct Conductometric
(Non-Selective Conductometric)
11%
21%
4%
Other
1. Is the TOC technology suitable for your specic application or water conditions? Many TOC technologies may be
suitable only for waters with a narrow range of organic or inorganic contaminants.
2. Are different models available to meet your current and future sampling needs (i.e. online, portable, laboratory)? Do
these models use similar technology to simplify method transfer or data comparability from lab to online?
3. Does the company offer the documentation and support necessary to help meet applicable industry or government regulations?
4. What is the companys level of experience supporting sales of TOC analyzers in your specic industry? Do they
understand the unique challenges specic to your application?
5. What type of service, applications, and technical support are available during and after the purchasing process?
55%
12%
6%
14%
13%
TOP 10 FEATURES/FACTORS
91%
EASE OF USE
76%
WARRANTY
68%
65%
57%
EASE OF INSTALLATION
45%
SPEED OF ANALYSIS
42%
40%
910=
760=
680=
650=
570=
450=
420=
400=
380=
370=
54
37%
For more information on TOC analyzers, including useful articles and a list of manufacturers,
visit www.labmanager.com/TOC-analyzers
Lab Manager
April 2015
LabManager.com
Sievers M9
TOC Analyzers
what the percent use is on those instruments. You first need to understand how
frequently the instruments are being
used, what they are being used for, and
when they are being used. If processes
are not automated, time is often wasted
in the overnight hours or early in the
morning when the instruments are
sitting idle. Automation can be set up to
run 24/7, but lab managers first need to
Lab Manager
April 2015
56
Dr. Nathaniel Hentz is assistant director of the analytical lab at the Golden LEAF
Biomanufacturing Training and Education Center (BTEC), where he develops bioanalytical
assays in support of the various biomanufacturing processes taught at BTEC. Since 2008,
Dr. Hentz has been responsible for developing and teaching undergraduate and graduate
courses, industry short courses, and government (FDA and BARDA) training courses,
with a focus on assay development and validation, quality control, and liquid-handling
performance. Dr. Hentz also directs the contract analytical services program at BTEC.
Prior to BTEC, he spent nearly 12 years developing high-throughput screening assays,
automating and optimizing laboratory equipment, and investigating new technologies
with Eli Lilly & Co. and Bristol-Myers Squibb. Dr. Hentz has also served as an independent
consultant in the automated liquid-handling quality control, microuidic separations,
and ADME/tox elds. He received his PhD in analytical chemistry from the University of
Kentucky in 1996, and his BS in chemistry from Eastern Michigan University in 1990.
LabManager.com
April 2015
Lab Manager
57
INSIGHTS ON WATER
TESTING LABORATORIES
Water testing laboratories hold a unique position among
analytical facilities in their interaction with broadly
diverse government and private entities.
The Guadalupe-Blanco River Authority (GBRA) is
a quasi-government organization covering all things
water-related in a 10-county Texas district. In addition
to testing, the authoritys activities include engineering,
hydroelectric power generation, and educational outreach.
The authoritys water testing laboratory, directed by Josephine Longoria, analyzes drinking water, wastewater, and
industrial water taken from and released to standing water
and rivers, as well as water from underground sources.
As part of the national Clean Rivers Program, the lab
also helps maintain water quality and health for the Guadalupe and Blanco rivers. GBRAs customers include local
water agencies and distributors, industrial companies, and
individuals seeking advice on well water quality.
Longorias lab is accredited by The NELAC Institute
(TNI), which provides certification via the National Environmental Laboratory Accreditation Program. The regulatory tangles water labs encounter arise from the alphabet
soup of authorities and regulations under which they work.
For GBRA these include, but are not limited to, the Clean
Water Act; the Resource Conservation and Recovery Act;
the Safe Drinking Water Act; and the Comprehensive
Environmental Response, Compensation, and Liability Act.
Texas laboratories must also deal with the Texas Commission on Environmental Quality (TCEQ), the Texas
Railroads Commission, and the Texas Clean Water Act.
Achieving TNI accreditation is expensive and time-consuming, Longoria says. Her lab is audited every two years
for quality practices. Only labs that test for customers outside their geographic domain require this qualification. But
labs should consider this level of accreditation so that test
results are more trustworthy; the data is more defensible.
Longoria practices what she preaches: When workloads
or analytes fall outside GBRAs capabilities, the samples
are outsourced, but only to TNI-accredited facilities.
58
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April 2015
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Ingeniously Practical
ohaus.com
facebook.com/ohauscorp
youtube.com/ohauschannel
twitter.com/ohaus_corp
1. Pipetting samples and standards at the Guadalupe-Blanco River Authority Regional Laboratory.
2. Microbiological assays are a significant part
of river health analysis at the Guadalupe-Blanco
River Authority Regional Laboratory. 3. Technician Justin Turner performs biological oxygen
demand analysis at Guadalupe-Blanco River
Authority Regional Laboratory.
2.
Hold time is huge, especially when your instrumentation decides not to work that day, Longoria says. She
advises lab managers to always have a Plan B in place
in the event of instrument or system failure, unwieldy
workflows, hold-time deadlines, or the absence of certain instrument operators.
Related advice applies to instrumentation. Outside of
LC-MS, water labs do not use many exotic analyzers. Ion
and nutrient analyzers tend to be robust, but they have their
limits in terms of stretching maintenance schedules. You
know your analyzers have been running hard for four months
straight and probably need to be shut down for preventive
maintenance, Longoria says. Dont wait for them to break
down. Assign regular maintenance times throughout the year.
Otherwise your instrument will go down at the worst time,
when youve just received a big load of samples.
60
Lab Manager
April 2015
3.
1010
10
9702.A1.1025-LAM 2015 Metrohm USA, Inc. Metrohm and design is a registered trademark of Metrohm Ltd.
(877) 315-3542
elgalabwater.com
email: elga.usa@veolia.com
BIOLOGICAL SAFETY
CABINETS
64
Lab Manager
Prepare a plan
April 2015
Up to speed
In general, keeping a BSC running keeps it safer
but can consume more energy. Some BSCs come
with a night mode, though, in which the viewing
screen can be closed, the lights are shut off, and the
airflow is reduced.
LabManager.com
The longer a BSC runs the more impact on the filter, which gets
loaded over time. Some BSCs have a magnehelic gauge that gives
a general idea of how much filter loading has taken place. As a
filter loads with particulates, some BSCs automatically adjust the
fan speed as needed to ensure adequate airflow for safety.
Knowing when a BSC last received service also impacts
its safety. There needs to be clear communication on
maintenance, says Thibodeaux. Only then can all of the users
be sure that they are working with a safe device.
Nonetheless, even different organizations recommend
different maintenance cycles. For example, Peters says, NSF
recommends to certify your cabinet annually, while USP
797 recommends twice a year. In a certification, says Peters,
your cabinet will be finely tuned to maximize safety through
airflows. He adds, Your certifier can also recommend when it
might be time to replace your BSC or if its in need of parts.
FOR ADDITIONAL RESOURCES ON BIOLOGICAL SAFETY CABINETS, INCLUDING USEFUL ARTICLES AND A LIST OF
MANUFACTURERS, VISIT WWW.LABMANAGER.COM/BSCS
survey says
CO2 INCUBATOR?
Water Jacketed
Air Jacketed
Direct Heat
36%
CO2 incubators are designed to copy a cells natural environment with a relative humidity of
around 95 percent, a temperature of 37C and a pH of 7.2 to 7.5. They are most common in
biology labs performing tissue or cell culture and are used in any process where cells need to be
cultured for a few hours or many weeks or where cells need to be expanded or maintained.
21%
Gel Jacketed
1%
Other
1%
TOP 6 QUESTIONS
1. What measures have been taken in the design to avoid contamination and what features are included to remove contamination?
77%
Research
Clinical
Quality Control
In Vitro Fertilization (IVF)
Other
18%
4%
2%
5%
32%
22%
18%
10%
6%
12%
TOP 10 FEATURES/FACTORS
770=
77%
75%
75%
EASE OF USE
74%
68%
WARRANTIES
59%
59%
59%
55%
750=
750=
740=
680=
590=
590=
590=
550=
540=
66
54%
For more information on CO2 incubators, including useful articles and a list of manufacturers,
visit www.labmanager.com/incubators
Lab Manager
April 2015
LabManager.com
Designed to achieve
The new Thermo Scientific Heracell VIOS CO2 incubator series represents a
new era in incubator design delivering performance, ease-of-operation, and value
required to support a range of culturing needs from basic research to demanding, leadingedge applications. By combining our latest technology advancements in contamination
control and uniform growth conditions with existing proven and reliable features, you are
now able to achieve your goals faster, more reliably, and with less effort.
2014 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are
the property of Thermo Fisher Scientific Inc. and its subsidiaries.
68
Lab Manager
April 2015
Cost of ownership extends to maintaining industryappropriate records, because audits and violations,
as Given might say, cost money. Highly regulated
industries or businesses should record and maintain
records in a form that cannot be doctored.
Factors to consider
When selecting a chiller, one
must strike a balance between
meeting the minimum
LabManager.com
FOR ADDITIONAL RESOURCES ON BATHS AND CHILLERS, INCLUDING USEFUL ARTICLES AND A LIST OF
MANUFACTURERS, VISIT WWW.LABMANAGER.COM/BATHS-CHILLERS
-125...+425C
www.huber-usa.com
Huber USA Inc. 100 Centrewest Ct. Cary NC 27513 Phone 1-800 726 4877 info@huber-usa.com
NITROGEN EVAPORATORS
FOR ADDITIONAL RESOURCES ON NITROGEN EVAPORATORS, INCLUDING USEFUL ARTICLES AND A LIST OF
MANUFACTURERS, VISIT WWW.LABMANAGER.COM/EVAPORATORS
MAKING SAMPLE CONCENTRATION EASIER AND GREENER
by Mike May, PhD
VACUU LAN
Local Vacuum Networks
by VACUUBRAND
Lab Mngr_Footer_Vacuu-lan-2.indd 1
www.vacuu-lan.com
1-888-882-6730
3/20/2015 3:58:54 P
PM
WEDNESDAY
MAY 13, 2015
www.labmanager.com/foodforthought
REGISTER NOW | Lab Manager Food for Thought Virtual Conference | Wednesday May 13, 2015
Food science involves the application of various techniques including microbiology, engineering, biotechnology, and
food chemistry. In a full-day virtual symposium, the editors of Lab Manager have gathered a group of industry experts
to discuss recent developments in four key areas of food science. With a focus on how to run your lab like a business,
our speakers will explore some of the latest techniques in laboratory informatics, food safety, food fraud detection,
and GMO identification. Join Lab Managers Food for Thought: The Latest Food Safety Tools & Techniques free
virtual event to explore the latest in food science technology, ask questions, and receive feedback from our experts.
FOOD FRAUD / FORENSICS Dr. Robert Hanner, University of Guelph, Centre for
Biodiversity Genomics, discusses new methodologies employing DNA testing and
genetic bar coding to crack down on food fraud.
GMO TESTING OF FINISHED PRODUCTS AND INGREDIENTS Dr. Heather Secrist, CEO,
Global Operations, Genetic ID, discusses the latest testing technologies used for GMO
identification and quantification.
survey says
ELECTRONIC LAB
NOTEBOOK?
Client/server
Web-based
Stand-alone
Thin client/server
Other
31%
23%
0%
5%
61%
45%
42%
42%
32%
21%
13%
13%
11%
11%
8%
Other
29%
19%
12%
12%
10%
9%
6%
3%
Electronic laboratory notebooks (ELNs), one component of a labs information infrastructure, help
laboratories capture and manage knowledge, streamline data management, protect intellectual
property and foster collaboration. Both non-specic/generic ELNs (which compete directly against
paper notebooks) and application/task-specic ELNs exist, each with their own fans.
TOP 6 QUESTIONS
TOP 10 FEATURES/FACTORS
83%
SECURITY
76%
63%
UP TIME
63%
VERSATILITY
59%
PRICE
59%
CUSTOMIZATION
58%
WEB-BASED ACCESS
55%
MULTI-PLATFORM
54%
EASE OF INSTALLATION
50%
830=
760=
630=
630=
590=
590=
580=
550=
540=
500=
72
For more information on electronic lab notebooks, including useful articles and a list of manufacturers,
visit www.labmanager.com/ELN
Lab Manager
April 2015
LabManager.com
products in action
Water conservation has become a topic of interest in modern lab design. And in keeping
up with current market needs, Labconco researched lab water usage and discovered one
major sink hole glass pipette washing.
Gallons upon gallons of tap water are poured
down the drain as the common, siphon-style,
pipette washers fill then drain repeatedly.
When washing is complete, rinsing generally
begins using deionized (DI) water a very
expensive solvent. After the time-consuming
process of washing and rinsing, the pipettes
must be carefully removed, sorted into drying
baskets and placed in an oven overnight. Total
elapsed time to wash and dry a single load of
pipettes more than 24 hours.
Tapping into our experience of designing and
manufacturing laboratory glassware washers,
we decided to address this issue. Combining
direct injection cleaning, scrubbing action of
percolation and consistency of automation, we
streamlined the washing process with considerably less water and substantially less time.
The new ScrubAir Pipette Washer/Dryer is a
one-of-a-kind automated unit to wash and dry
in one place. The durable, steel-constructed unit
can wash, rinse and dry up to 60 pipettes with
Lab Manager
73
survey says
WATER PURIFICATION
SYSTEM?
ASTM Type I
ASTM Type II
ASTM Type III
Other
30%
8%
9%
62%
60%
47%
TOP 4 QUESTIONS
22%
3. Where do you need the system in the lab(s)? Consider: top of counter, under counter or wall mounting the unit. What
is the overall footprint/real estate of the system(s) and components?
21%
5%
Achieving water of a high quality requires the careful use of purication technologies and a
method for accurately measuring and monitoring contaminants.
43%
Water is the most commonly used laboratory reagent; however, the importance of water quality is
often overlooked. Because impurities can be a critical factor in many research experiments, water
purity ranks high in importance. There are several types of impurities and contaminants in water such
as particulates, organics, inorganics, microorganisms and pyrogens that can adversely affect results.
36%
12%
28%
8%
4%
12%
4. What kind of warranty and service is provided? Is the system manufactured to quality standards and which ones? Is
this a pharmaceutical application that needs to be validated?
TOP 10 FEATURES/FACTORS
87%
DURABILITY OF PRODUCT
81%
EASE OF USE
79%
74%
69%
68%
66%
65%
56%
WARRANTIES
53%
870=
810=
790=
740=
690=
680=
660=
650=
560=
530=
74
For more information on water purification systems, including useful articles and a list of manufacturers,
visit www.labmanager.com/water-purification
Lab Manager
April 2015
LabManager.com
2015 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the
property of Thermo Fisher Scientific Inc. and its subsidiaries.
how it works
PRESSURE-BASED MICROPLATE
VOLUME MEASUREMENT
Problem: In virtually all research processes in which analytes and reagents are mixed in microplates,
precise information on the starting volume in each plate well is critical to the accuracy and success of
the process, as well as the results derived from it. While effective tools for measuring the dispensing
of liquid volumes by pipettes have been available for years, accurate volume measurement of what is
actually in the plate at a given time has been a challenge. Scenarios where this presents a roadblock
include compound library management, compound dilution and plate replication, and high-throughput
screening. In applications where samples have been stored for periods of time, environmental factors
and process errors may affect the plate volume, and it is not uncommon to find that a storage plate
contains less volume than expected.
Solution: The new Artel VMS directly measures the
The VMS is suited for any lab transferring rare and expensive
samples and reagents, including compound management and
crop science laboratories, where the known volume present
in a plate is a critical piece of information. In these settings,
samples may be taken in and out of storage multiple times.
Using DNA extraction as an example, measuring the volume
of starting materials helps determine the correct amount of
reagent necessary to perform the extraction.
76
Lab Manager
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LabManager.com
LONG BEACH, CA
July 26th 31st, 2015
TECHNOLOGYNEWS
Hydrophobic Interaction Columns
ANALYTICAL
CDS-7500
Features the ability to change between thermal desorption tubes for air analysis and VOA vials for soil and/
or water analysis
Also able to connect to different front end concentrators
such as the CDS-7000 purge and trap concentrator, Dynatherm 9300, and even PT systems from OI and Tekmar
Compatible with different manufacturers sorbent tubes
CDS Analytical
www.cdsanalytical.com
GPC/SEC Platform
OMNISEC
rIQ
CRAIC
Malvern Instruments
www.microspectra.com
Flame
Dumatec 8000
FOSS
www.foss.dk
Ocean Optics
UV-1280
Veraspec
High performance gas sampling systems designed for the analysis of high
pressure reaction processes up to atmospheric pressure
Suited to the study of gas kinetics of atmospheric reactions, clusters and
high pressure plasmas
Feature the MAX quadrupole mass filter, a 19mm rod diameter triple
filter quadrupole
MAX quadrupoles are available in mass range options up to 16,000 amu
Henniker Scientific
78
Lab Manager
April 2015
www.henniker-scientific.com
www.oceanoptics.com
UV-Vis Spectrophotometer
www.malvern.com
Miniature Spectrometer
www.thermoscientific.com
Shimadzu
www.ssi.shimadzu.com
LabManager.com
PTR-TOFMS System
PTR-QiTOF
IONICON
www.ionicon.com
Connect 2 Cleanrooms
BASIC LAB
Mini HeightChek
Asynt
Distek
www.asynt.com
www.distekinc.com
Asynt
www.connect2cleanrooms.com
Hotplate Stirrers
Built from Trespa Toplab Basea brand of high pressure laminate plategiving an attractive appearance
and a range of inherent benefits
Chemical-resistant, antistatic, has low dirt pick-up,
is easy to clean, and is scratch-resistant
Can be created bespoke to requirements and a core
range of sub-assemblies will be kept in stock for a
short delivery time
Dolomite
www.asynt.com
www.dolomite-microfluids.co.uk
Peristaltic Pumps
Masterflex Catalyst
Cole-Parmer
www.coleparmer.com
SampleGenie 4
Genevac
www.genevac.com
April 2015
Lab Manager
79
edge Series
Hanna Instruments
AQUACOUNTER AQV-2200S
www.hannainst.com
JM Science
Digital Refractometer
HI96800
Hanna Instruments
JM Science
www.hannaisnt.com
CentriVap micro IR
UniFlow CE
Hemco
www.hemcocorp.com
Labconco
80
Lab Manager
www.iattlabgas.co.uk
April 2015
www.labconco.com
AiroGen
IATT
www.jmscience.com
Vacuum Concentrator
www.jmscience.com
Are Class I biological safety cabinets, meeting requirements for non-sterile powders and particulates contained
during hazardous drug manipulation
These true bag-in/bag-out HEPA-filtered powder hoods
include a canopy and damper for thimble ducting the
enclosure to the outside
Feature a deep interior of 23.4 as well as an ergonomic
air foil with Clean-Sweep airflow openings
RXPert
Labconco
www.labconco.com
LabManager.com
Viscometer
microVISC-m
HPR-Micro Reactor
RheoSense
www.rheosense.com
Defender Series
Rainin TerraRack
METTLER TOLEDO
Manual Capper
www.mt.com/rainin
Univo CM480
OMEGA
www.supercriticalfluids.com
Micronic
www.micronic.com
INFORMATICS
www.omega.com
LMT
www.sovella.us
Visiun
www.visiun.com
April 2015
Lab Manager
81
ChEMBL v.20
Now incorporates the Hierarchical Editing Language for Macromolecules (HELM), the macromolecular representation standard recently released by the Pistoia Alliance
Can be used to represent simple macromolecules (e.g. oligonucleotides, peptides and antibodies)
complex entities (e.g. those with unnatural amino acids) or conjugated species (e.g. antibodydrug conjugates)
In the future, will enable researchers to query content in new ways
European Bioinformatics Institute
www.ebi.ac.uk
Brooks Automation
LAB AUTOMATION
LIFE SCIENCE
Artel
Bio-Plex ProTM
www.artel-usa.com
ddPCRTM KRAS
Bio-Rad
Lab Manager
April 2015
www.bio-rad.com
BioFlo 320
He adds that Andrew is easy to set up, connecting to most computers using a USB cable and
taking no more than five minutes to get going. Plug Andrew into a standard 120V outlet, USB
connection to a computer, and you are ready to automate your protocols whether on a bench,
fume hood, or in a cold room, Roler says.
82
Our approach was novel in the industry and allows our customers to use the tools they already
own and that have been trusted for accuracy and robustness for decades, says Scott Roler,
director of sales and marketing at Andrew Alliance USA.
www.bio-rad.com
The system requires little to no maintenance, though Andrew Alliance suggests following the
recommended guidelines for the actual manual pipette calibration to assure accuracy of the
system as a whole.
Bio-Rad
PRODUCT SPOTLIGHT
While the system currently works with Gilson Pipetman Classic and now Rainin LTS pipettes,
Roler says the company hopes to expand this offering in the future. And, the new Andrew
Calibro accessory, allows the unattended verification of manual pipette performance using
photometric methods. The Calibro can test a set of five pipettes in roughly two hours with no
intervention or action from the user, Roler explains.
www.brooks.com
Eppendorf
www.eppendorfna.com
LabManager.com
Automated platform is designed for the magnetic bead-based purification of nucleic acids
from a wide range of biological samples
Features a uniquely-designed magnetic beadbased processing chamber
Fully integrated with easy to use, sample
specific, pre-packaged reagent kits to process a
wide range of bio-specimens
Offers excellent yield, purity, reliable performance, flexibility, and convenience
MP Biomedicals
www.mpbio.com
GemCode Platform
10X Genomics
Bioreactor Systems
qPCR System
Prime Pro 48
Techne
www.10XGenomics.com
www.techne.com
Sartorius Stedim
PRODUCT SPOTLIGHT
www.sartorius.com
CILS-8/9000
CILS International
www.cils-international.com/usa
Feature high rigidity to minimize distortion before and after thermal cycling
Produced in Class 10,000 cleanroom conditions
Certified free of pyrogens as well as DNAse and RNAse
enzyme activity, enabling routine achievement of
excellent PCR results
Based upon a well design that eliminates sample
carryover problems when using a plate lid
Porvair Sciences
www.porvair-sciences.com
April 2015
Lab Manager
83
Informatics Infrastructure
in the QA/QC Lab
By Trish Meek, Director of Product Strategy, Thermo Fisher Scientific
Laboratories across every industry are looking for more integration in their labs and more connectivity
with the rest of their organization. SampleManager is a fully integrated laboratory platform comprising
Laboratory Information Management (LIMS), Scientific Data Management (SDMS) and Lab Execution (LES).
QA/QC Labs
Integrated informatics enable labs to execute and manage all lab processes easily, with the data rigor and
intelligence that lab managers require to drive efficiency and profitability for the lab and for the business.
Conclusion
their guide.
Trish Meek is Director of Product Strategy for the Informatics business at Thermo Fisher Scientific.
To learn more about Integrated Laboratory Informatics, visit www.thermoscientific.com/SM11
or email us at marketing.informatics@thermofisher.com.
products in action
10 Technology Drive
Wallingford, CT 06492
+01-203-678-2000
www.protononsite.com
info@protononsite.com
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Lab Manager
April 2015
Safety First
Ensuring safety is paramount for a facility that
deals with thousands of liters of hydrogen
gas each day, considering a single hydrogen
cylinder storing 6,300 liters of gas has the
explosive potential of 35 lbs of TNT. A facility
with hundreds of GC systems fed by cylinders
of hydrogen has a tremendous explosive
potential, so a lab manager that opts for
delivered cylinders has to invest in significant
safety infrastructure to mitigate those risks. By
replacing those cylinders with a single centralized Proton OnSite hydrogen gas generator
that only produces gas when necessary and
has a limited capacity, labs can dramatically
reduce both the explosive potential and the
amount of time and money spent handling
heavy, dangerous cylinders.
Making the Helium Switch
Make Sense
Most laboratories are facing a future with a
less reliable and more expensive helium gas
supply, causing them to explore their carrier
gas options. Large labs that wish switch to
on-site hydrogen gas will have to invest in
many small hydrogen generators for each lab,
creating upfront costs that can be tough to
justify. But, hydrogen is quickly becoming less
expensive than helium and is a more efficient
LabManager.com
Matters
Helmer Scientific,
the company
you trust, now
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TrueBlue
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PROFILES
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Contact:
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Deliver your message and position your products and brand in front
of more buyers and key decision-makers in print and online than any
other resource available today.
For more information visit www.labmanger.com
88
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Sonntek Ad_3.25x2.indd 1
LabManager.com
2014-10-14 11:25 AM
pharmaceuticals@fedequip.com
8200 Bessemer Ave., Cleveland, OH 44127
ADVERTISER INDEX
Company
URL
Page
Company
URL
Page
Aries Filterworks
www.arieslterworks.com
27
www.metrohmusa.com
23,61
BAKER
www.bakerco.com
65
Mettler Toledo
www.mt.com
BINDER Inc.
www.binder-world.us
22
Miele, Inc.
www.miele-pro.com
17
www.biospec.com
51,88
NASMM
www.naosmm.org
77
Biotek Instruments
www.biotek.com
NuAire Inc.
www.nuaire.com
BMT USA
www.bmtus.com
46
Ohaus
www.ohaus.com
59
www.brandtech.com
43
OI Analytical
www.oico.com
12
Conquer Scientic
ConquerScientic.com
89
Panasonic Healthcare
www.twinguardseries.com
coylab.com
31
PolyScience
www.polyscience.com
29
www.drummondsci.com
37
Proton Onsite
www.ProtonOnSite.com
25
Eberbach
www.eberbachlabtools.com
26
www.labspacesolutions.com
14,88
ELGA
www.elgalabwater.com
63
Ruro
www.ruro.com
21,45
EMD Millipore
www.millipore.com/ultrapure
SARSTEDT
www.sarstedt.com
15
www.eppendorfna.com
11
www.sartorius.com
20
www.fedequip.com
89
SE International, Inc.
www.seintl.com
38
GE Analytical Instruments
www.geinstruments.com
55
Sonntek, Inc.
www.sonntek.com
88
Genevac
www.genevac.com
35,88
SPECTRO Analytical
http://icp-oes.spectro.com/BLUE
92
Glas-Col, LLC
glascol.com
16
www.thermoscientic.com
13,19,39,41,67,75
Helmer Scientic
www.helmerinc.com
87
Tosoh Bioscience
www.tosohbioscience.com
91
www.huber-usa.com
69
Universal Electric
starlinepower.com
47
IKA Works
www.ika.com
62
Vacuubrand, Inc.
www.vacuubrand.com
70
INTEGRA
www.integra-biosciences.com
33
The Advertisers Index is provided as a reader service. Although every attempt has been made to make this index as complete as possible, the accuracy of all listings cannot be guaranteed.
April 2015
Lab Manager
89
Internalization
Degradation
2
LAB MANAGER
ONLINE
We look back at our web content since the April issue and look forward to whats in store for the upcoming May issue.
1 Growing Forward
Two cannabis testing labs from Colorado share their thoughts on how the states
emerging recreational marijuana industry
has affected them, discussing the challenges they face, the key technologies they use,
how they motivate their staff, and the excitement of being at the forefront of an
emerging industry.
Read more at LabManager.com/growing-forward
Lab Manager
April 2015
The number of laboratory apps has grown significantly over the past few years as researchers have come to accept the technology. Previously focused on applications within
the lab, newer apps offer remote access to instruments from outside the lab as well.
LabManager.com
www.tosohbioscience.com
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