Safety Data Sheet: According To EC Directive 91/155/EEC

Safety Data Sheet
According to EC Directive 91/155/EEC

Date of issue:
1.
17.01.2004
Identification of the substance/preparation and of the company/undertaking

Identification of the product
Catalogue No.:
100060
Product name:
CAYE Broth modified acc. to EVANS for the culture of pathogenic

E.coli to enhance verotoxin production during growth
Use of the substance/preparation

In Vitro Diagnostic Medical Device
Reagent for analysis
Company/undertaking identification
2.
Company:
Merck KGaA * 64271 Darmstadt * Germany * Phone: +49 6151 72-0
Emergency telephone No.:
Please contact the regional Merck representation

in your country.
Composition/information on ingredients
Preparation contains inorganic and organic compounds.
Hazardous ingredients:
Name according to EC Directives:
CAS-No.
EC No.
EC-Index-No.
Classification
Content:
Tris(hydroxymethyl)aminomethane
77-86-1
201-064-4
Xi; R36/38
10 - < 20 %
(Full text of R-Phrases in heading 16)
3.
Hazards identification
No hazardous product as specified in Directive 67/548/EEC.
4.
First aid measures

After inhalation: fresh air.
After skin contact: wash off with plenty of water. Remove contaminated clothing.
After eye contact: rinse out with plenty of water with the eyelid held wide open. Call in
ophtalmologist if necessary.
After swallowing: make the victim drink plenty of water, induce vomiting. Call in physician.
The Safety Data Sheets for catalog items are also available at www.chemdat.info
Page 1 of 5
Merck Safety Data Sheet

Catalogue No.:
Product name:
5.
100060
CAYE Broth modified acc. to EVANS for the culture of pathogenic E.coli to
enhance verotoxin production during growth
Fire-fighting measures
Suitable extinguishing media:
powder, foam, water.
Special risks:
Combustible. Development of hazardous combustion gases or vapours possible in the event of fire. The
following may develop in event of fire: phosphorus oxides.
Special protective equipment for fire fighting:
Do not stay in dangerous zone without self-contained breathing apparatus.
Other information:
Prevent fire-fighting water from entering surface water or groundwater.
6.
Accidental release measures

Person-related precautionary measures:
Avoid inhalation of dusts.
Environmental-protection measures:
Do not allow to enter sewerage system.
Procedures for cleaning / absorption:
Take up dry. Forward for disposal. Clean up affected area. Avoid generation of dusts.
7.
Handling and storage

Handling:
Protect from light.
No further requirements.
Storage:
Tightly closed. Dry. At +15C to +25C.
8.
Exposure controls/personal protection

Personal protective equipment:
Protective clothing should be selected specifically for the working place, depending on
concentration and quantity of the hazardous substances handled. The resistance of the
protective clothing to chemicals should be ascertained with the respective supplier.
Respiratory protection:
required when dusts are generated.
Eye protection:
required
Page 2 of 5

Catalogue No.:
Product name:
100060
Hand protection:
In full contact:
nitrile rubber
0.11 mm
> 480 Min.
Glove material:
Layer thickness:
Breakthrough time:
In splash contact:
nitrile rubber
0.11 mm
> 480 Min.
Glove material:
Layer thickness:
Breakthrough time:
The protective gloves to be used must comply with the specifications

of EC directive 89/686/EEC and the resultant standard EN374, for
example KCL 740 Dermatril (full contact), 740 Dermatril (splash
contact).
This recommendation applies only to the product stated in the safety
data sheet and supplied by us as well as to the purpose specified by
us. When dissolving in or mixing with other substances and under
conditions deviating from those stated in EN374 please contact the
supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Industrial hygiene:
Change contaminated clothing. Wash hands after working with substance.
9.
Physical and chemical properties

Form:
Colour:
Odour:
solid
beige
peptone-like
pH value
(25 C)
at 39.75 g/l H2O
Melting point
Boiling point
Ignition temperature
Flash point
Explosion limits
8.3-8.7
(after autoclaving)
not available
not available
not available
not available
lower
not available
upper
not available
Density
Solubility in
water
not available
(20 C)
39.75
g/l
10. Stability and reactivity

Conditions to be avoided
no information available
Substances to be avoided
no information available
Hazardous decomposition products

in the event of fire: See chapter 5.
Page 3 of 5

Catalogue No.:
Product name:
100060
11. Toxicological information

Acute toxicity
Quantitative data on the toxicity of this product are not available.
Further toxicological information

Property that must be anticipated on the basis from the components of the preparation:
After inhalation: Irritations of the mucous membranes, coughing, and dyspnoea.
After skin contact: Slight irritations.
After eye contact: Slight iritations.
After swallowing of large amounts: nausea, vomiting, agitation, confusion, cyanosis.
Further data
The product should be handled with the care usual when dealing with chemicals.
12. Ecological information

Ecotoxic effects:
Quantitative data on the ecological effect of this product are not available.
Further ecologic data:
Do not allow to enter waters, waste water, or soil!
13. Disposal considerations

Product:
Chemicals must be disposed of in compliance with the respective national regulations. Under
www.retrologistik.de you will find country- and substance-specific information as well as
contact partners.
Packaging:
Merck product packaging must be disposed of in compliance with the country-specific regulations
or must be passed to a packaging return system. Under www.retrologistik.de you will find special
information on the respective national conditions as well as contact partners.
14. Transport information

Not subject to transport regulations.
15. Regulatory information

Labelling according to EC Directives
Symbol:
R-phrases:
S-phrases:
-------
Page 4 of 5

Catalogue No.:
Product name:
100060
16. Other information

Text of any R phrases referred to under heading 2:
36/38
Irritating to eyes and skin.
Regional representation:
This information is given on the authorised Safety Data Sheet
for your country.
The information contained herein is based on the present state of our knowledge. It
characterizes the product with regard to the appropriate safety precautions. It does not
represent a guarantee of the properties of the product.
Page 5 of 5

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Safety Data Sheet

According to EC Directive 91/155/EEC

Identification of the substance/preparation and of the company/undertaking

CAYE Broth modified acc. to EVANS for the culture of pathogenic

Use of the substance/preparation

Merck KGaA * 64271 Darmstadt * Germany * Phone: +49 6151 72-0

Emergency telephone No.:

Please contact the regional Merck representation

(Full text of R-Phrases in heading 16)

First aid measures

Merck Safety Data Sheet

Accidental release measures

Handling and storage

Exposure controls/personal protection

required when dusts are generated.

Merck Safety Data Sheet

The protective gloves to be used must comply with the specifications

Physical and chemical properties

at 39.75 g/l H2O

10. Stability and reactivity

Hazardous decomposition products

Merck Safety Data Sheet

11. Toxicological information

Further toxicological information

12. Ecological information

13. Disposal considerations

14. Transport information

15. Regulatory information

Merck Safety Data Sheet

16. Other information

Irritating to eyes and skin.

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