Muleta Propo - Commented Sep. 15, 2018
Muleta Propo - Commented Sep. 15, 2018
Muleta Propo - Commented Sep. 15, 2018
September, 2018
Harar,Ethiopia
Acknowledgment
I would like to express my deepest gratitude to my adiviser Dr Bezatu Mengistie (PhD) associate
professor of public health and Education development center coordinator college of Health
and Medical Sciences of Haramaya University and Dr Tadese Alemayehu (PhD) Haramaya
University,Guiding me in developing and preparing this theses for the fulfillment of masters
of post graduate in MPH program .
Table of contents
Acknowledgment....................................................................................................................................i
Table of contents...................................................................................................................................ii
List of tables.........................................................................................................................................iv
Abbreviations........................................................................................................................................v
Abstract................................................................................................................................................vi
1 Introduction.......................................................................................................................................1
1.4 Objectives.....................................................................................................................................6
2. Literature review...............................................................................................................................7
4.3 Discussion………………………………………………………………………………………………………………….…. 35
4.4Concluton…………………………………………………………………………………………………………………….…36
Recommendation…………………………………………………………………………………………………………………
37REFERENCE……………………………………………………………………………................
38
Curriculumvite…………………………………………………………………………………46
APPROVAL SHEET……………………………………………………………………………… 47
LIST OF TABLES
Table 1: Socio demographic characteristics of podoconisis patients’ case-control study Guliso
woredas, West Wolega, Oromia Region, Western Ethiopia, 2018
Table 2: Daily base practices of podoconisis respondents’ case-control study Guliso woredas,
West Wolega, Oromia Region, Western Ethiopia, 2018
Table 3: Factors associated with podoconiosis respondents’ case-control study Guliso woredas,
West Wolega, Oromia Region, Western Ethiopia, 2018
GC Gregorian calendar
HO Health Officer
LF Lymphatic Filariasis
Objective: To identify associate factors with podoconosis patients’ age group 15-64 in Guliso
woredas, community based case control study from May 30 to October 30, 2018.
Methods: A community based case control study design employed. The data was collected using
structured questionnaire quantitative methods. Five kebeles selected from the 29 kebeles of the
woredas. Patients previously identified as having podoconiosis and a healthy comparative
(control) group of households with the same aged in the same Kebeles selected to be included in
the study. Data were collected, coded and entered into EpiData 3.1 and analyzed by Statistical
Package for Social Science (SPSS) 23.0. Logistic regression analysis was used and dependants
and independents variables was measured using 95% CI and the p< 0.05was considered as
statistically significant. Descriptive statistics used and presented by frequency tables, graphs and
charts.
Result: A total of 200 participants (100 cases, 100 controls) completed the study questionnaire
by making 100% response rate. The mean age of the study participants for the case was 42.94
years (SD 11.42 years) and 40.40 years (SD 11.89years) for the controls. Level of education,
elementary (p=0.001; AOR=6.37, 95%CI(2.163-18.782), high school and above(p=0.005;
AOR=3.89, 95% CI (1.507-10.054), history of farming (p=0.004;COR=.316, 95%CI(.143-.698),
family relationship with podoconiosis patient (p=0.001; AOR 0.132: 95% CI 0.061-0.287),
income(P= 0.018; AOR 0.234; 95% CI: 0.070-0.783), age for first shoe(p=0.001; AOR .362:
95% CI .196 - .669) and curability of the Podoconiosis (p=0.001,AOR=.334, 95%CI(.179-.624)
were statistically significant predictors for podoconiosis.
Conclusion: However, the onset of diseases is not limited on age as well as sex but which is
based on prolonged soil-foot exposure this finding identified that educational level, occupation
(being farmer), family relationship, income, age of first shoes wearing, curability about
podoconiasis was strongly associated with Podoconiosis which need control measurements for
these predictors.
1. Introduction
Podoconiosis is a chronic, progressive, disabling and disfiguring disease exclusively affecting the
lower limbs. It is a type of lower limb tropical elephantiasis distinct from lymphatic filariasis
(LF). Podoconiosis is also known as “mossy foot” due to the moss-like disfigurement of the
lower limb.The prevalence of podoconiosis in the population of 1197/392556 was 3.05%.The
podoconoisis was significantly higher among women than men (3.67% vs 2.4%). Most (92.2%)
people with podoconiosis were in the economically active age group (15–64 years) ( Gail.
D,2010)
Podoconiosis is caused by prolonged exposure to red clay soils of volcanic origin when tiny
silica crystals are absorbed through the feet ( Fikresilasie et al, 2015)
In Africa, it is widely prevalent in countries associated with rift valley geological complex
including Ethiopia, Kenya, Tanzania, Rwanda and Burundi. Common features of endemic areas
are high altitude above 1250m , annual rainfall above 100mm , average annual temperature of
200c, and soils of volcanic origin (Kenate .Bet al 2016)
In Ethiopia , the basalt area covers more than 200,000 km 2, approximately one-fifth of the land
surface. High soil fertility in these areas attracts an agricultural population of 20.5 million
people. (Fikresilasie ,etal 2015)
Climatic conditions, primarily altitude, rainfall, precipitation and temperature, influence the
weathering of rocks and determine the type of soil generated, which in turn probably influences
the distribution of podoconiosis. High altitude areas >5% are characterized avarege mean >1500
mm, temperature between 19–21oC, mean annual rainfall>1500 mm and mean annual
precipitation >130 mm. The distribution of podoconoisis is limited under certain environmental
conditions, presumably those conditions favorable for the weathering of rock to produce specific
types of soil (Tekola et al. 2006).
Guliso woreda is one of the affected areas in western party of West Wollega zone, Oromia region of
Ethiopia . The Woreda is located 500 km west of Addis Ababa, the capital city of Ethiopia, and has an
altitude of 1,500–1,800 m above sea level. The population of the woreda is 69,856, of which 88.7% live
in 26 rural kebeles. The economic base for most of population is agriculture, which allows prolonged
contact with the local soil and are subsistence farmers producing coffee as a cash crop. The area is known
for the presence of podoconiosis for a long time. Most of the studies on podoconiosis in Ethiopia were
done in this area. According to the most recent prevalence survey, which was done in the Woreda
in 2011, it is estimated that there are about 1935 podoconiosis patients in the woreda were
registered (Getahun, A.et al )
The socio-demographic and other characteristics of controls living in the three different levels of
podoconiosis endemicity were compared to assess existence of basic differences among these
groups. Comparing the average income, there was no statistically significant difference between
controls living in ‘high’ and ‘low’ endemicity areas (mean difference = 21.8, t = 1.2, p = 0.231),
whereas a significant difference in income was observed after adjusting for sex. In general,
controls living in the ‘medium’ endemicity area earned less than controls living in ‘high’ or ‘low’
endemicity areas.(AOR = 0.5, 95% CI = 0.4–0.7) (Yordanos .B,etal).
The majority 315 (85.1%) of people with podoconiosis washed their feet at least once per day
(mean 1.4±0.086), and 79 (21.4%) washed their feet with soap daily. Almost all (345, 94.3%)
had washed their feet on the night before the interview was conducted. Foot washing behaviour
did not change in 97 (26.2%) people with podoconiosis after their leg started to swell (Bekele K,
et al.2016).
The experience of wearing shoes did not vary between males and females. However, the type and
quality of shoe worn varied, more males than females wearing the better quality and more
expensive leather shoes (19.6% vs. 8.7%, χ2 = 7.4, p = 0.007) ( Alemu .G,et al, 2011)
The mean age at first shoes wearing was 25.94±13.83 (range 4–95) years. During the interview,
162 (43.8%) were wearing closed plastic shoes, while 32 (8.6%) were barefoot. A small but
important subset (21, 5.7%) had never worn shoes. (Bekele K, et al.2016)
Although the social consequences of the disease are indicated at different times, there is no
concrete evidence that fully describe the problem to attract the attention of responsible parties.
Even if podoconiosis is a preventable disease by simply wearing a protective shoe, it can be said
that it is a neglected public health problem by the Minister of Health, the regional health bureau
and even by the World Health Organization. Hence the objective of this study is to investigate
the awareness and knowledge of people on associate factors and social consequence of the
disease and to fulfill the gap.
1.2Statement of the problem
Globally, it is estimated that there are at least four million people with podoconiosis. The disease
has been reported in more than 20 countries, of which ten had high burden of the disease. In
endemic highland areas of these countries podoconiosis is more prevalent than commonly
known diseases such as HIV/AIDS, tuberculosis, malaria, or filarial elephantiasis (Davey et
al. 2007).
Podoconosis is highest in Cameroon and Ethiopia. In Ethiopia,9.1% of podoconiosis cases live in areas
with irritant red clay soil (Gail .D, 2010 )
Study conducted in northern Ethiopia,A community based case control case-control study carried
out in six kebeles (the lowest governmental administrative unit) shows three endemicity levels:
‘low’ (prevalence <1%), ‘medium’ (1–5%) and ‘high’ (>5%). A total of 142 (30.7%) households
had two or more cases of podoconiosis. It is estimated that up to 1 million cases of podoconiosis
(i.e. 25% of the global total case load) exist in Ethiopia. The ‘at-risk’ population for podoconiosis
is made up of all the people who live and farm on irritant soil. The soil is estimated to cover 18%
of the surface area of Ethiopia, on which estimated 22–25% of Ethiopia’s population (19.3
million) lives. In endemic areas of Ethiopia, the prevalence of podoconiosis is high: 9.1% in
Illubabor Zone, Oromia Region; 6% in the Pawe resettlement area, northwest Ethiopia; 5.5% in
Wolayta zone, SNNPR; 2.8% in GullisoWoreda, West Wollega zone, Oromia region, 7.4% in
Midakegni, West Shewa Oromia region, 3.3% in Debreelias and Dembecha, East and West
Gojjam, Amhara region (Tekola et al. 2006)
Across-sectional quantitative study was conducted Bedele Zuria woreda, west Ethiopi in 2011
and involved a house-to-house survey in all 2285 households shows the prevalence of
podoconiosis was 5.6% (379/6710) (95% CI 5.1–6.2%) and was significantly greater among
women than men (6.6% vs 4.7%; p = 0.001). A total of 311 (16.9%) households had at least one
member with podoconiosis, and 128 (33.8%) study participants reported having a blood relative
with podoconiosis. Two hundred and forty-three (76.4%) podoconiosis patients were in the
economically productive age group of 15–64 years. On average, a patient experienced at least six
episodes of adenolymphangitis per year resulting in a loss of 25 working days per year (Fasil.T,et
al,2011).
Podoconiosis has severe health, social and economic consequences. According to a study in
Ethiopia, the annual economic cost of podoconiosis in an area with 1.7 million residents was
more than 16 million United States dollars (US$) (Kebede.D, 2015).
When extrapolated to the national population, this result indicates a corresponding cost of more
than US$ 200 million. Some studies suggested that the total direct cost of podoconiosis is
amounted to the equivalent of US$ 143 per patient per a year (Fikresilasie,etal .2015).
Most people with podoconiosis in Ethiopia experience an episode of acute inflammation that
may be triggered by bacterial, viral or fungal infection. Patients experienced an average of 5.5
ALA episodes annually, each of average 4.4 days, thus 24 working days were lost annually.Since
podoconiosis patients become bedridden during such attacks, it leads to loss of producti vity
(Deribe K, et al. 2015). Some studies suggested that the total direct cost of podoconiosis is
amounted to the equivalent of US$ 143 per patient per a year (Fikresilasie,etal .2015)
From a total of 128 patients (40.8% [64/157] of men and 28.9% [64/222] of women; χ2 = 4.6; p =
0.028) reported having a blood relative with podoconiosis. Of these, 97 (75.8%) reported having
one or more affected close relatives (sibling, parent or grandparent). There was at least one
member with podoconiosis in 311 households (16.9%) and 70 of these households (22.5%) had
two or more podoconiosis-affected members. Of the households reporting two or more affected
members, 32 (45.7%) included an affected couple (Fasil,T.et al 2011)
Podoconosis disease leads to social exclusion of individuals and their families. The most
Pronounced social stigma in endemic areas are often unable to marry, excluded from school,
church, and social events (Tekola et al. 2006).
The social impact of podoconiosis is also substantial. In endemic areas of southern Ethiopia, the
disease is considered to be the most stigmatizing health problem. Affected people may be
excluded from school, denied participation in local meetings, Churches and mosques and
excluded from marriage with unaffected individuals. In northern Ethiopia,People with
podoconiosis were found to have lower quality-of-life scores, in all domains of quality of life,
compared to healthy people from the same neighborhoods. (Kebede,D.2015 ).
Social stigma related to podoconiosis has a major impact on the psycho-social well being of
patients and their children. The disease leads to social exclusion of individuals and their families.
Patients commonly reported that they had considered suicide in response to discrimination and
prejudice, particularly in interpersonal interactions. Unable to marry, forced divorce, dissolution
of marriage plan, insults and exclusion from school and social events were some of the most
commonly mentioned forms of enacted stigma reported patients (Fikresilasie,T, 2015)
Recently, podoconiosis and other NTDs have been receiving attention in Ethiopia. The Federal
Ministry of Health of Ethiopia endorsed inclusion of podoconiosis in the National Master Plan
for Neglected Tropical Diseases in 2011, and nationwide mapping of podoconiosis and lymphatic
filariasis was conducted in 2013 (Gail. D, 2010).
Inthis study factors associated which predispose to podoconoisis was identified. The study was
conducted because there was knowledge gap in terms of what factors are contribute to the
problem. Addressing the gap in turn helps in the improvement of awareness on the community.
The recommendations made by this study may play a role towards improving effective planning
healthy services. In addition,it may be useful to other studies as reference while conducting
further studies on the problems.
The findings of the study is helpful for community, stake holders , local governmental health
planners, and other organizations working on health areas to consider these community health
problems during planning and designing an intervention strategies, monitoring and evaluation of
their activities with active participation of the community. It can also provide supplementary
baseline information for researchers who want to further investigate and intervene on the
podoconiosis and other neglected tropical disease.
1.4 Objectives
A case–control study was done in Kamwenge District, Western Uganda, September 2015 ,
tested the hypothesis that the disease was caused by prolonged foot skin exposure to irritant
soils, using 40 probable case-persons and 80 asymptomatic village control-persons, individually
matched by age and sex. The suspected cases (40) with onset from 1980 to 2015. Prevalence
rates increased with age; annual incidence (by reported onset of disease) was stable over time
at 2.9/100,000 and resulted that 93% (37/40) of cases and 68% (54/80) of controls never wore
shoes at work ( AOR) = 7.7; 95% [confidence interval] CI = 2.0–30); 80% (32/40) of cases and
49% (39/80) of controls never wore shoes at home (AOR) = 5.2; 95% CI = 1.8–15); and 70%
(27/39) of cases and 44% (35/79) of controls washed feet at day end (versus immediately after
work) (AOR = 11; 95% CI = 2.1–56) (Christine ,et al, 2015).
According to study done in Ethiopia in ,2015,individual and environmental factors were found
to be risk factors for podoconiosis. Thus, individual-level factors associated with an increased
risk for podoconiosis included female gender (odds ratio [AOR] = 1.3; 95%% BCI; ( 1.2–1.4),
age (AOR = 1.02; 95% BCI; 1.02–1.03), unmarried status (AOR = 1.4; 95% BCI; 1.3–1.5),
religion; factors associated with a decreased risk included secondary or higher education,
increased foot hygiene, employment, housing with covered floor (OR = 0.3; 95% BCI; 0.3–0.4).
(Kebede D, etl,2015)
According to study done in Soddo Zuria Woreda, Wolaita Zone South Ethiopia,Eighty (5.4%) of study
participants were affected by podoconosis disease. And the significantly contributed factors for
Prevalence of podoconiosis in the study area were age above 26 years (AOR=4.15, 95% CI=1.50-11.51),
washing practice only by water (AOR=1.86, 95% CI=1.08-3.81)(Alemtsehay E,etal2016)
According to this study done in Soddo Zuria District, Wolaita Zone, South Ethiopia , January 25-
February 20, 2015Community-based cross-sectional study was conducted on 703 households
(1483 Participants) in selected 3 kebeles and participated. Age, educational status, age of first
shoes wearing, feet washing practice, regular walking on bare foot and time spent on farming on
barefoot were the independent variables which found in this study as predictors of Podoconiosis.
80(5.4%) of study participants had affected by the disease. The significant contributed factors for
prevalence of Podoconiosis in study area were age above 26 years (AOR=4.15, 95% CI=1.50-
11.51), (Alemtsehay E,etal2016)
Washing practice in Soddo Zuria Woreda, Wolaita Zone South Ethiopia ,only by water (AOR=1.86,
95% CI=1.08-3.81), regular walking on barefoot for different social purpose (AOR=4.18, 95%
CI=1.84-9.46), time spent on farming on barefoot who travelled above mean hour (AOR=2.23,
95% CI=1.31-3.80),the educational status who were illiterate (AOR=9.74, 95% CI=1.29-73.53)
and primary level (AOR=2.23, 95% C=1.33-3.73) and age of first shoes wearing (AOR=8.14,
95% CI=2.61-25.40) (Alemtsehay E,etal2016)
People those who have dirty and cracked status of feet in Soddo Zuria Woreda, Wolaita Zone South
Ethiopia ,were 2.77 times more likely to develop Podoconiosis than those who have clean and
intact feet status (COR=2.77, 95% CI=1.75-4.37, p=0.00). On other hand the participants
washing practice dependent on only by water were 1.73 times more likely to develop
Podoconiosis than who washed by water and soap (COR=1.73, 95%CI= 1.06-2.84, p=0.03). The
participant who travelled regularly for social purpose were 3.44 times more likely to develop
Podoconiosis than those who not travelled (COR=3.44, 95% CI=1.68-7.02, p=0.01). (Alemtsehay
E,etal,2016)
A case control study conducted in the northern Ethiopia shows the majority of the cases,
especially women, were less educated (AOR = 1.7, 95% CI = 1.3 to 2.2), were unmarried (AOR =
3.4, 95% CI = 2.6–4.6) and had lower income (t = −4.4, p<0.0001). On average, age started
wearing shoes ten years later than controls. Among cases, age of first wearing shoes was
positively correlated with age of onset of podoconiosis (r = 0.6, t = 12.5, p<0.0001). Among all
study participants average duration of shoe wearing was less than 30 years (Yordanos .B,etal,2015
).
A case-control study conducted in East Gojam zone ,2015, with more than 2.1 million
inhabitants in northern Ethiopia households had two or more cases of podoconiosis compared to
controls, the majority of the cases, especially women, were less educated Odds Ratio = 6.74,
95% CI (1.3 - 2.2) (Yordanos ,B,et al,2015)
According to crossectional study in Wayu Tuka Woreda 2015,the prevalence was significantly
higher among women than men (3.67% vs 2.4%) and most (92.2%) people with podoconiosis
were in the economically active age group (15–64 years. On average, people with podoconiosis
had 23.3 episodes of ALA/year and each person with podoconiosis lost 149.5 days of
activity/year. Never walking barefoot associated with decreased odds of ALA (AOR=0.23; 95%
CI 0.06 -0.80 and daily foot washing (AOR 0.09; 95% CI 0.01 to 0.75) (Kenate B, etal 2016).
According to study done in Ethiopia ,2017, total of 1113 study participants (379 cases and 734
controls) were included giving for a response rate of 96.95%. Positive family history (AOR, 2.81
[95% CI: 1.7–4.64]), bare foot (AOR, 3.26 [95% CI: 2.03–5.25]), poor foot hygiene (AOR, 2.68
[95 CI: 1.72 – 4.19]) increase the risk of Podoconiosis. Female gender (AOR, 0.26 [95% CI:
0.15–0.44]), good housing condition (AOR, 0.17 [95% CI: 0.1–0.3]), medium income (AOR,
0.12 [95 % CI: 0.07– 0.22]) and primary education (AOR, 0.02 [95% CI: 0.01–0.04]) decrease
the risk of Podoconiosis.
2.1.4 .Cultural factor.
According to crossectional study in Wayu Tuka Woreda 2015 ,marital status of people was
assessed between cases and controls were compared and classified into married and unmarried
(single, divorced, separated or widowed), and unmarried people had three times greater odds of
disease than married people (AOR = 3.4, 95% CI = 2.6–4.6, p<0.0001) Stratified analysis by sex
among cases and control assessed, showed that affected women had greater odds of being
unmarried than affected men (AOR = 3.7, 95% CI 2.4 - 5.5, p<0.0001) (Kenate B, etal 2016).
In a study conducted in Sodo Zuria Woreda, Ethiopia never walking barefoot and daily foot
washing were associated with lower odds of ALA. People with podoconiosis who never walked
barefoot had one-quarter the odds of ALA as those who walked barefoot at times (AOR=0.23,
95% CI 0.06 to 0.80, p=0.025). People with podoconiosis who washed their feet daily had one-
twelfth the odds of ALA as those who did not (AOR=0.09, 95% CI 0.01 to 0.75, p=0.023)
(Kenate B, etal 2016)
Acording to study done in Soddo Zuria Woreda, Wolaita Zone South Ethiopia regular walking
for different social purpose on barefoot (AOR=4.18, 95% CI=1.84-9.46), time spent on farming
above mean hour in farming on barefoot (AOR=2.23, 95% CI=1.31-3.80) , educational level of
being illiterate (AOR=10.14, 95% CI=1.3777.00) and age of first shoes wearing (AOR=8.14,
95% CI=2.61-25.40) of the participants were associated with podoconosis.(Alemtsehay
E,etal,2016)
2.2. Conceptual framework
Geographical factor
Economical factor
Location
Income
Weather
Productivity
Accessibility healthy facility
Podoconoisis
Socio demographic factors
mmmmmmmm
Age, sex,ethnicity,religion,
marital status, educational
status, ,
Social factor
Cultural factor
Poverty
Stigmatizing
Distance from health
Isolation
service
Access to water supply
Figure 1: Conceptual frame work adopted and modified from malnutrition and Environmental
Health: (Mikko K.Paunio anAnjali Achary)
3 Methods and Materials
The area is also has combination of tropical, sub tropical and temperate climate. Both live stock
rearing and crop cultivation (mixed farming) is product of the area. For many decades the
population in the area has had access to well functioning health services though near-by hospital
and clinics run by non-governmental organizations. The population has also had above-average
primary and secondary education resulting in a relatively higher literacy rate than the national
average for rural areas in Ethiopia. Majority of the woredas ethnic group are represented the
largest groups include the oromo (99.1%) and (09%) otheres like amhara and gurage and
Languages spoken is oromiffa.
The religion with the most believers in the area is Orthodox with 10% of the population, while
2.5% are Muslim, the rest (87.5%) are protestants.( Guliso woreda health office ,2017)
3.2. Study Design
A community based case control study design was employed and supplemented with quantitative
methods.
r d2 1 (0.25)2
A list of kebeles in Guliso woreda known for the presence of podoconiosis, based on a previous
podoconiosis survey has been obtained. The study was a case control quantitative research
design. The 5 kebeles were randomly selected by simple random sampling method. Individuals
with podoconiosis over 15 years of age were selected from the registration list generated. The
patients were selected based on accessibility of their homes for data collectors. House hold with
podoconiosis cases and house hold without cases were randomly selected from each of the five
podoconiosis kebeles. For each participant with podoconiosis were selected those controls with
out Podoconiosis were matched with age and sexwere randomly selected and who were
caregivers to non school-aged children will be passed over for the study.
Age
Sex
Ethnicity
Religion
Marital status
Educational status
Occupation
Family size
Family relationships
Income
Productivity
ALA: Acute adenolymphangitis - Acute infection, occurs on average 5 times per year. Patients
become pyretic with a warm, painful limb, necessitating on average of 4.5 days off work for each
episode (Fikresilasie,etal ,2015). These episodes appear to be related to progression to a hard,
fibrotic leg, a reddish, hot, swollen leg with a painful groin.
Data collectors were trained about the purpose of the study and how to administer the
questionnaire. Role play by trainees were done to strengthen their skills in administering the
questionnaire and how to approach participants in the field.
During data collection, questionnaires were checked for completeness on a daily basis by the
immediate supervisors. Incorrectly filled or missed questionnaires were sent back to the
respective data collectors for correction and checked by supervisor’s sent and submitted to the
principal investigator after checking its consistency and completeness. The investigators also
recheck the completed questionnaires to maintain the quality of data.
There were discussion with data collectors and supervisors accordingly if there was a problem
encountered during data collection. Data quality was ensured during data coding, cleaning, entry
to computer and during analysis.
Residence
Urban 1 0
Rural 99 100
Educational status
Can’t write and read 33 17
Elementary 59 50
Secondary school 7 23
Diploma(level I-IV) 1 9
University and above 0 1
Marital status
Single 15 15
Married 77 89
Widowed 6 5
Divorced 2 0
Occupation
Farmer 90 74
Daily laborer 5 4
Government 0 12
employee
Others 5 10
Religion
Protestant 100 98
Orthodox 0 2
Ethnicity
Oromo 100 99
Amhara 0 1
Daily income
Yes 4 16
No 96 84
From the study finding, 54(58.5%) of the participants who had podoconiosis cases responded
that as they have had about one to four family size and 46(41.5%) had five and above family but
the controls have responded that 63(58.5%) had one to four and 37(41.5%) have had five and
above family size. According to this finding about 4(10.5%) of family had showed very poor
relationship due the presence of podoconiosis and 7(23.5%) of them had poor relationship. In the
contrary about 47(41.7%) and 42(24.5%) of the family had showed good and very good
relationship with their family who infected with podoconiosis respectively.
Daily bases practices on hygiene of foot care about podoconiosis
As shown on table 2 below from 100 cases 68 of them responded as they wear shoes daily and
about 62 from the controls did the same. But when asked the time point for wearing shoes
majority of them responded during adult and almost all of them wore shoes when interviewed
about podoconiosis. Almost both cases and controls responded that as there is the availability of
water for washing their foot and about 50% of them can access(get) this water with a short
distance of not more than within 10 minutes walking distance to fetch the water. People The
proportion of with bare foot among cases and controls was ere 92.0% and 87.0% respectively.
Table 2: Daily base practices of podoconisis respondents’ case-control study Guliso woredas, West
Wolega, Oromia Region, Western Ethiopia, 2018
Yes 97 95
No 3 5
Availability of water for Washing foot
Yes 99 99
No 1 1
Distance in time to get water
<10minutes 55 45
15-30minutes 45 54
>30minutes 0 1
Barefoot
Yes 92 87
No 8 13
Time of barefoot
During farming 5 7
In the field 0 2
At home 52 46
At anytime 43 45
Nearby health facility
Yes 100 99
No 0 1
Distance of health facility
<5km 69 51
5-10km 36 33
>10km 3 8
Variable assignment during regression was coded as 0, 1 and 2. Those assigned under 0 were
cannot write and read, other occupation, poor/very poor relationship, no response, childhood age.
And 1 represented elementary (primary school), farmers, good/very good response, yes response,
and adulthood age response while 2 represented high school and above for educational status
only. Bivariate and multivariablte logistic regression was performed in order to identify the
strength of association and to assess factors associated with the podoconiosis. The variables that
showed less than 0.25 of p-value were reanalyzed in the multivariablte logistic regression and
some predictors were identified by controlling confounding factors. Comparing male and female
cases and controls there was no statistically significant difference.
The study subjects who found under elementary school were 6.37 times more likely to know
about Podoconiosis than those who didn’t get formal education (can’t write and read)
(p=0.001;AOR=6.37,95%CI(2.163-18.782)
The study subjects who found under high school and above were 3.89 times more likely to know
about Podoconiosis than those who were below school and didn’t get formal education level
(p=0.005; AOR=3.89, 95% CI (1.507-10.054).
The participants, who work on farm, were 31.6% lessmore likely to develop Podoconiosis than
those
work other activities (p=0.004;COR=.316, 95%CI(.143-.698)
The odds of Podoconiosis was 86.8% lower among persons relationship on the family living with
podoconiosis in the family (p=0.001; AOR 0.132: 95% CI 0.061-0.287). Not wearing shoes
during childhood increases decreases the risk of Podoconiosis by 63.8% (p=0.001; AOR .362:
95% CI .196 - .669). The odd of Podoconiosis was 76.6% higher lower among people with low
income (P= 0.018; AOR 0.234; 95% CI: 0.070-0.783) than those???.
The participants, who responded yes on the cure about podoconiosis, were 66.6% less likely to
know about Podoconiosis curability than those who responded no (p=0.001, AOR=.334, 95%CI
(.179-.624).
Table 3: Factors associated with podoconiosis respondents’ case-control study Guliso woredas, West
Wolega, Oromia Region, Western Ethiopia, 2018
Discussions
In this study, there are factors that have been affecting podoconios respondents both in case and
controls. The mean age of the cases was 42.94 years while the mean age of controls was 40.40
years which indicated that the cases were about two years older than the controls. Age and sex
were grouped under potential factors for the development of Podoconiosis in different studies
and significant factor but in this study they are not significant which might be due to the time of
the study and sampling technique. The experience of wearing shoes did not vary between males
and females in this study which is inconsistent with the previous study. Level of education,
history of farming (occupation), family relationship with podoconiosis patient, income, age for
first shoe and curability of the Podoconiosis were statistically significant predictors for
podoconiosis.
The study subjects who found under elementary school were 6.37 times more likely to know
about Podoconiosis than those who didn’t get formal education (can’t write and read) (p=0.001;
AOR=6.37, 95%CI (2.163-18.782). This finding agrees with previous finding done in Ethiopia(.
The study subjects who found under high school and above were 3.89 times more likely to know
about Podoconiosis than those who were below school and didn’t get formal education level
(p=0.005; AOR=3.89, 95% CI (1.507-10.054). Educational level is a prior risk factor and
outcome of Podoconiosis. This means, when educational level of an individual showed a gap
there is the chance of getting the disease that increases and people tend to stop their education
after the disease onset.
Age of wearing first shoe was significantly associated with the age of onset of Podoconiosis and
one predictor for not wearing during early childhood age. Not wearing shoes during childhood
increases decreases the risk of Podoconiosis by 63.8% (p=0.001; AOR .362: 95% CI .196 - .669).
This finding is consistent with the previous finding on west Ethiopia, East and West Gojam
indicating that most patients might have started wearing shoe after the development of
Podoconiosis that they didn’t do before.
Income is a predictor for podoconiosis and this study assessed the household income however
the study acknowledge that the reported income may be biased because of different cultural and
other barriers including estimation of the income made by the subjects.
Conclusion
Podoconiosis is the disease of all age groups and both sex but it showed significant difference in
educational level, occupation, family relationship, income, age of wearing shoes and curability of
podoconiosis. However, the onset of diseases is not limited on age as well as sex but which is
based on prolonged soil-foot exposure on both factors. According to this finding, educational
level, occupation (being farmer), family relationship, income, age of first shoes wearing,
curability about podoconiasis was strongly associated with podoconiosis.
Strength and Limitations of the study
Community based household survey identified that the problem of the podoconiosis cases in the
five randomly selected Kebeles for the future intervention and might be the generalizability for
the zonal health bureau that they can react on the case with the regional and federal health
bureau. The main limitation of this study is recall bias because to make it more clear for the
respondents the interviewer asked them repeatedly.
Recommendation
Advocacy for shoes as a health intervention and effort should focus to address the community,
the policy makers and other concerned bodies on education & awareness creation. For those
individuals who cannot afford to buy shoes, support financially distribution – possibly by means
of collaboration with shoe companies be supposed to be considered. Extending similar
collaborations to other shoe companies would be beneficial. By using as opportunity on
observed increased shoe wearing practice educating of the community is needed. Effective
prevention could be possible based on early age shoe wearing, foot washing practice and
appropriate utilization of shoes. Podoconiosis control and prevention programmes should involve
the low income and uneducated populations. Establishing anti-Podoconiosis, doing with
woredas, zonal, regional and federal health bureaus as needed for the community.
Finally, continued research should focus on the development of good point-of-care diagnostic
tests for podoconiosis, which are needed both to detect new cases and, ultimately, to verify
elimination and Scholars should test the effect of all these variables with further longitudinal
studies.
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English questionnaire to assess associated factors of podoconoisis patient among 15-64 age
group,Kebele -------------------------------- Interviewer No. ------------------------Interviewee No.
-------Woreda/Town------------------------ Date of interview----------------
1 Sex Male
Female
25-34
35-44
45-54
55-64
>65+
Rural
Elementery(1-8)
Secondary(9-12)
Diploma (level1-4)
Marired
Widowed
Divorced
Separated
Others
Merchant
Daily laborer
Government employee
Other
Protestant
Muslim
Catholic
Others
Oromo
Gurage
Tigrai
Others
9 Family size 1-4
>5
Good
Very good
No
2 If yes at what age did you started to wear At child hood/5/years
shoes?
No
5 How long you walk to get water from water <10 munits
source?
15-30 munits
>30 munits
6 Do you have experience of walking bare foot Yes
before ?
No
7 If yes when did you have experienced walking During ploughing/farming/
bare foot?
In the field
At home
At any time
No
9 If yes,How far your house from healthy facility <5 km
in km ?
5-10 km
>10km
Sadarkaa tokkoffaa(1-8)
Fuudheera
Daldalaa
Hojjetaa guyyaa
Hojjetaa mootumaa
7 Amantiin kee maali? Orthodoksii
Protestants
Musliima
kaatolikii
kan biro
8 Lammumaan kee maali? Amaara
Oromooo
Guragee
Tigiraay
kan biro
9 Baayina maatii keessanii hoo? 1-4
>5
10 Haala dhibee miila dhiitaa / Abbaan ni qaba
podoconiosis/ maatii keeti? Haati ni qabdi
Lammanuu qabu
,Abbaa Haadha fi ijoollee keesa tokko
Lakki
2 Yoo deebbiin kee eeyyee ta’e umurii meeqatti Yeroo mucumaat waggaa
kophee ka’achuu eegalte? <5
Yeroo umurii barnootaa
Waggaa 6-7
Yeroo saafilummaa 7-13
Lakki
5 Fageenya hagam deemta bishaan argachuufi? <10 daqiiqaa
15-30 daqiiqaa
>30 daqiiqaa
Lakki
7 Yoo deebiinkee eeyyee ta’e gaafii lakk 6 Yeroo hojii qottisaa
fyoomfa’a miilla qullaa deemta turte?
Dirree keessa
Sex Male
Nationality Ethiopian
Phone No 0912053339
E-mail muleteolana@gmail.com
Skills
HARAMAYA UNIVESTY
Title:factors associated podoconisis in Guliso woreda, West Wolega, Oromia Region, Western Ethiopia :
community based case control study .
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