Complications of Caesarean Section: Review
Complications of Caesarean Section: Review
Complications of Caesarean Section: Review
12280 2016;18:265–72
The Obstetrician & Gynaecologist
Review
http://onlinetog.org
Please cite this paper as: Field A, Haloob R. Complications of caesarean section. The Obstetrician & Gynaecologist 2016;18:265–72. DOI: 10.1111/tog.12280
emergency caesarean was 6.75% and 4.74% for elective Should initial surgical and medical attempts to arrest
caesarean. Risk factors included placenta praevia, general bleeding fail, there are several second-line options. Some
anaesthesia, obesity, labour dystocia, antepartum/ units have access to interventional radiology services that are
intrapartum haemorrhage, birthweight of greater than 4 kg able to find and embolise specific bleeding points and,
and the presence of uterine fibroids.6 ideally, patients with morbidly adherent placenta should
Haemorrhage at caesarean occurs for a number of reasons, deliver in a unit with access to interventional radiology.
including uterine atony, tissue trauma (for example, uterine Internal iliac artery ligation may be attempted, although this
angle extensions, cervico-vaginal trauma, bladder injury or is a procedure many obstetricians are not familiar with.
bleeding from adhesions), coagulation defects and problems Ultimately, hysterectomy may be necessary; although when
with the placenta. The treatment of haemorrhage at caesarean done at caesarean it is associated with high rates of
must be directed at the cause. Uterine atony is treated with complications, including bladder trauma, ureteric injury
uterotonic medications, such as syntocinon, ergometrine, and re-laparotomy as discussed by Sackinki et al.9 in their
carboprost and misoprostol. If these fail, surgical methods case series.
such as intrauterine tamponade balloon and/or compression
sutures (for example, B Lynch) should be employed.7
Postoperative sepsis
Bleeding due to trauma can be minimised by using a
careful surgical technique. The uterus should be checked for Caesarean section is the most important risk factor for
dextro-rotation and this should be corrected prior to uterine postpartum sepsis, which may arise from a number of
incision. Similarly, care should be taken to avoid opening the sources. Wound infection and endometritis are the
uterus too inferiorly, especially in the advanced stages of commonest sites of postoperative infection, although the
labour when the lower segment may be difficult to delineate. urinary tract, respiratory tract and nervous system must also
The fetal head should be gently disimpacted and delivered be considered. The risk of sepsis is, unsurprisingly, higher for
through the uterine incision. These measures reduce the risk emergency compared with elective caesarean section. A 2014
of uterine angle extensions, broad ligament trauma and Cochrane review suggested a rate of wound infection of 97
urinary tract injury.7 per 1000 and 68 per 1000 for emergency and elective
Bleeding as a result of trauma should be arrested by caesarean section, respectively; for endometritis the rates
prompt surgical repair. Uterine angle extensions should be were 184 per 1000 versus 39 per 1000.10 The review also
repaired, ensuring that the angles are adequately secured. showed that prophylactic antibiotics led to a relative risk of
Extensions downwards and laterally may be close to the endometritis of 0.38 (95% confidence interval [CI]
ureters. Tears in the lower segment extending downwards 0.34–0.42),10 hence prophylactic antibiotics prior to skin
towards the bladder should be closed from apex to incision are one of the most important ways of reducing
incision.7 The bladder may need to be mobilised further postoperative sepsis.10 Meticulous attention to haemostasis
to prevent inclusion within sutures but should also be and appropriate consideration and placement of drains may
checked to ensure it is not damaged. Extensions upwards also lead to a reduction in postoperative collections.11
into the upper segment should be closed in a similar Wloch et al.12 examined other risk factors and found that
fashion to a classical caesarean section, carefully obesity and maternal age under 20 years were independent
documented and accompanied by advice for future risk factors for surgical site infection, and that rates of
deliveries.7 There may be a complete hole in the broad infection were lowest when the caesarean section was
ligament and possible extension into the posterior aspect of performed by a consultant.12 The overall rate of surgical site
the uterus; this hole should be closed to prevent bowel infection was 9.6% and the commonest organisms isolated
herniation. Within the broad ligament lie both branches of were Staphylococcus aureus, anaerobes and enterobacteriaceae
the uterine arteries as well as the uterine arteries themselves, such as Escherichia coli (E. coli) and enterococcus.12
which can be torn. Haemostatic sutures can be placed to A Cochrane review from 2014 found that routine
secure bleeding and, if needed, the uterine vessels can be preoperative vaginal cleansing with povidone-iodine
ligated. This is done by taking a suture through the lateral solution reduced the risk of postpartum endometritis
aspect of the uterus at the level of the incision and back (relative risk 0.45, 95% CI 0.25–0.81) but showed no
through an avascular window within the broad ligament, or statistically significant effect on wound infection or pyrexia.13
the broad ligament can be opened.7 There is little definitive evidence regarding wound closure
Bleeding from the placental bed, such as with placenta and the risk of sepsis. A 2012 Cochrane review examined
praevia or placenta accreta, can be managed with figure of wound closure techniques at caesarean section.14 The two
eight haemostatic sutures or intrauterine balloon most commonly compared methods were staples and
tamponade.7 Intravenous tranexamic acid may be a useful subcuticular absorbable sutures. There was no statistically
adjunct in all cases of haemorrhage.8 significant difference in terms of pain, cosmetic appearance
retrograde bladder filling with contrast via an indwelling can assess patency and has the advantage over intravenous
catheter. If there is a suspicion of upper renal tract injury as urogram in that it images other pelvic organs in the case of
well or diagnostic uncertainty, CT with intravenous contrast diagnostic uncertainty. Delayed sequences may be needed to
may be required.22 see if contrast is collecting outside the ureter. If diagnostic
uncertainty remains then cystoscopy with formal retrograde
ureterogram can be done, but this is more invasive than
Ureteric injury
either an intravenous urogram or CT.26
Ureteric injury at caesarean section is substantially less Management depends on the injury and location: partial
common than bladder injury but much less likely to transection may be treated by ureteric stent placement,
be recognised intraoperatively.23 A large audit of complete transection may be managed by
11 284 caesareans found 16 cases of bladder injury and 4 cases ureteroneocystostomy (re-implantation of the proximal
of ureteric injury, giving a rate of 0.27 per 1000 caesarean ureter into the bladder) or ureteroureterostomy (re-
sections. Rajasekar and Hall23 reported that all bladder injuries anastomosis of the cut ureter),27 and occlusion with a
were noted intraoperatively, whereas only 1 of the 4 ureteric suture may be treated by removal of the suture and/or
injuries were detected as it co-existed with a bladder injury.23 stenting of the ureter, if needed. A case series from Turkey
Other sources state that ureteric injuries are missed looked at ureteric injuries diagnosed late after caesarean
intraoperatively in approximately 70% of cases.24 section and managed percutaneously.28 The average time to
The ureters may be damaged in several ways but the recognition was 21 days but the maximum delay in diagnosis
commonest during caesarean are transection and ligation (or was 8 months. They performed anterograde pyelography to
kinking) by a suture. Transection can occur when there is delineate the lesion, followed by percutaneous nephrostomy.
extension of the uterine incision into the broad ligament. In In cases of obstruction, they performed weekly pyelograms
this situation, they are also at risk of inclusion within a suture through the nephrostomy and awaited dissolution of the
during attempts at haemostasis because of the close sutures. They also reported that five cases of partial
proximity of the ureters to the uterine arteries.25 The transection, including one of ureterovaginal fistula, were
ureters are also at risk where they join the bladder and, in treated entirely percutaneously. Overall 75% of ureteric
this case, may be damaged as part of a concomitant bladder injuries were managed percutaneously.28
injury or attempts to repair a bladder injury.23,26
Whereas bladder injury is usually obvious during caesarean Bowel injury
section, ureteric injury is not and there must be a high index
of suspicion to find it. If there is concern, a urologist should Immediate bowel injury is a rare complication and the RCOG
be contacted. Intravenous injection of dye and transurethral consent advice does not list bowel injury as a serious risk, but
cystoscopy can be used to demonstrate ureteric patency.26 rather refers to the possibility of bowel repair as an additional
When not recognised intraoperatively, ureteric injury may procedure.29 Compared with bladder injury, there is much
present in a number of ways depending on the injury, less published literature on intraoperative bowel injury. The
location and length of time postoperatively. Bilateral distended gravid uterus displaces the bowel from the
complete occlusion or transection of the ureters will result operative field at caesarean section; however, the bowel can
in postoperative anuria. Other signs and symptoms include still be damaged in several ways. Loops of bowel may be
fever, haematuria, flank pain, abdominal distension, sepsis/ adherent to the anterior abdominal wall, particularly if there
peritonitis/ileus, or retroperitoneal urinoma formation. has been a history of surgery via midline incision, and may be
There may be urinary leakage from the vagina suggesting damaged during peritoneal entry or if extensive division of
fistula formation or from the abdominal wound or drain adhesions are required prior to delivery. After delivery, the
suggesting intra-abdominal urine collection.26 Renal function bowel can be damaged during closure. While the uterus is
testing may suggest renal failure due to obstructive being closed, particularly if there are angle extensions, it is
nephropathy in the case of occlusion or metabolite possible to include loops of bowel within the sutures,
reabsorption where there is transection. Conversely, it may posterior to the uterus. Exteriorisation of the uterus allows
present much later with secondary hypertension because of direct visualisation of the posterior aspect of the uterus and
obstructive nephropathy.26 should be considered if there are significant extensions.
If ureteric injury is suspected postoperatively then imaging It is essential to diagnose bowel injury intraoperatively and
should be done to confirm and identify the nature and site of ask a surgeon to attend for the repair. These injuries may
any injury. Renal ultrasound is useful for visualising the often be treated with primary closure if small, even in
kidneys and identifying hydronephrosis. It is noninvasive but unprepared bowel, but if larger or multiple they may require
cannot confirm continuity of the ureter or identify the exact resection of the damaged bowel segment. It is vitally
level and nature of obstruction. CT with intravenous contrast important to avoid damaging the bowel with diathermy as
thermal injury may be difficult to spot and the patient may nasogastric tube. Renal function and electrolytes should be
present 48–72 hours later with bowel perforation secondary checked and abnormalities corrected. Opiate analgesia, which
to tissue necrosis.30 can impede bowel function, should be minimised.35
There is little specific literature on management of bowel The main diagnostic challenge is excluding the unlikely
injury at caesarean. A case series of ten patients from 2011 but more serious causes of bowel obstruction; these
looked at primary repair against colostomy and concluded include immediate postoperative adhesion formation,
that primary repair should be attempted for all traumatic intra-abdominal sepsis, Ogilvie syndrome, and
colonic injuries and intraperitoneal rectal injuries. The causes unrecognised intraoperative bowel injury. For patients
of bowel trauma in this case series were predominantly failing to improve with simple conservative measures or
penetrating abdominal trauma, so caution needs to be used who appear more unwell than expected for postoperative
when considering generalisability to iatrogenic ileus, an abdominal X-ray is a useful initial investigation.
surgical injury.31 Gas throughout the abdomen, including both large and
Bowel injury not recognised intraoperatively will usually small bowel, is more suggestive of paralytic ileus, whereas
present with signs and symptoms of intra-abdominal sepsis. distended loops of small bowel with no gas in the colon is
This may be delayed for several days in the case of more suggestive of a mechanical obstruction. X-ray allows
perforation following diathermy injury. CT imaging may be the caecal diameter to be measured if Ogilvie syndrome is
undertaken and show extraluminal air and fluid, although suspected. Similarly, a CT scan of the abdomen gives the
these may also be a normal finding in the immediate same information but will also show intra-abdominal
postoperative period. Distended loops of bowel, evidence of collections and show the obstruction transition point of
inflammation/abscess formation and, particularly, the bowel more precisely.35
extravasation of oral contrast material are much more
suggestive of gastrointestinal perforation.32 Re-operating in
Ogilvie syndrome
the presence of peritonitis is much more likely to require
colostomy than if injuries are identified at the time of Ogilvie syndrome is defined as acute large bowel obstruction
primary surgery. without a mechanical cause.36 It is not specific to caesarean
section but can occur in any patient undergoing surgery and,
indeed, has been reported in nonsurgical patients with
Postoperative ileus
serious underlying medical conditions. The exact
Postoperative ileus refers to severe constipation and pathophysiology is unknown but it may be due to an
intolerance of oral intake due to non-mechanical causes imbalance in the autonomic innervation of the distal colon
after surgery. It may be a normal, physiological response to leading to atony and subsequent proximal dilatation. During
abdominal surgery, but may also occur in patients after other a caesarean section, Ogilvie syndrome may be caused by
forms of surgery. The pathogenesis of postoperative ileus is damage to the sacral parasympathetic nerve supply, which
not fully understood and causation is likely to be runs close to the cervix, vagina and broad ligament.36 The
multifactorial.33 The incidence of ileus after gynaecological classic presentation is progressive abdominal distension,
procedures has been estimated to be 10–15% although there which may initially be painless and associated with varying
is a paucity of specific data for caesarean section. A 2014 degrees of constipation. As the caecum becomes more
systematic review examining the role of chewing gum in dilated, the pain worsens, localising to the right-hand side
reducing postoperative ileus after caesarean section suggested with associated tachycardia. Eventually there is caecal
an incidence of approximately 12% in the control group and ischaemia, perforation and peritonitis.
that chewing gum may reduce the risk to 5%.33 There should be a high index of suspicion in postcaesarean
Ileus presents with anorexia, nausea and vomiting, absence women with progressive abdominal distension. Initial
of flatus, pain and distension worsening from time of management is with intravenous fluids, analgesia,
surgery. The symptoms are variable depending on the site of correction of electrolyte imbalances, nasogastric tube
bowel involved. Lower gastrointestinal involvement may insertion and an abdominal X-ray. Early involvement of the
feature absence of flatus with minimal distension and general surgical team and senior obstetrician is
tolerance of oral intake whereas upper gastrointestinal recommended. Imaging usually shows grossly dilated loops
involvement may feature distension, vomiting and of large bowel, especially the caecum. It has been suggested
intolerance of oral intake with the preservation of flatus.34 that for caecal diameters of less than 10–12 cm, conservative
Intravenous fluid replacement, anti-emetics and the management should be attempted with consideration of
limitation of oral intake are used to manage postoperative intravenous neostigmine. For caecal diameters of greater than
ileus. Patients with significant distension, especially if 10–12 cm, the patient should have urgent colonic
accompanied with intractable vomiting, may benefit from a decompression with a rectal flatus tube. Most patients will
Ureter injury Approx 0.4% 1. Correct for dextro-rotation prior to uterine 1. Urology opinion
incision 2. Ureteric occlusion:
2. Caution when repairing extensions and
operating near broad ligament i. Suture removal
3. Caution when repairing bladder injuries ii. Ureteric stenting
iii. Nephrostomy
3. Ureteric transection:
i. Re-anastomosis
ii. Re-implantation
Postoperative ileus Approx 12% 1. Careful bowel handling 1. Exclusion of more serious pathology
2. ?Chewing gum postoperatively 2. IV fluid replacement
3. Correction of electrolytes
4. Anti-emetics
5. Gastric drainage
6. Minimise opiates
deeply impacted head. Fetal head lifting devices are under time of operation and are easily corrected either by
evaluation and have been associated with statistically the operating surgeon or by seeking assistance from
significant reductions in operating time, incision to delivery other specialties.
time and uterine extensions, although the evidence base is
limited.40 The use of such devices is not currently routine or Disclosure of interests
recommended outside of an audit or research trial.40 AF is the National Trainees’ Committee Representative for
Health Education East of England and also sits on the RCOG
Complications of caesarean section in Professional Development Committee.
resource-poor countries
Contribution of authorship
Caesarean section rates have increased rapidly in many low- and RH instigated, co-wrote and edited the article. AF researched,
middle-income countries, a trend that might have serious effects co-wrote and edited the article.
on maternal health, particularly physical and socioeconomic
consequences of caesarean section in resource-poor countries.
An analysis by Vogel et al.41 showed that caesarean section rates References
in low human development index countries increased by 6% 1 Health & Social Care Information Centre. NHS Maternity Statistics - England,
between 2004–08 and 2010–11. A study carried out in Matlab, 2013-14. Leeds: hscic; 2015 [http://www.hscic.gov.uk/catalogue/
PUB16725].
Bangladesh used interviews with women and their families to 2 World Health Organization. Rising caesarean deliveries in Latin America: how
show that women were often poorly informed about the best to monitor rates and risks. Geneva: World Health Organization, 2009 [http://
indication and expected complications for their caesarean apps.who.int/iris/bitstream/10665/70034/1/WHO_RHR_09.05_eng.pdf].
3 Gedikbasi A, Akyol A, Asar E, Bingol B, Uncu R, Sargin A, Ceylan Y. Re-
section. In addition, women undergoing caesarean section laparotomy after cesarean section: operative complications in surgical
incurred high costs, leading to economic burdens on other delivery. Arch Gynecol Obstet 2008;278:419–25.
family members and a sense of blame directed at the 4 Ragab A, Mousbah Y, Barakat R, Zayed A, Badawy A. Re-laparotomy after
caesarean deliveries: risk factors and how to avoid? J Obstet Gynaecol
women themselves.42 2015;35:1–3.
Caesarean sections performed at regional hospitals may be 5 National Institute for Health and Care Excellence. Caesarean section. NICE
associated with higher rates of complications when compared clinical guideline No. 132. Manchester: NICE; 2011.
6 Magann EF, Evans S, Hutchinson M, Collins R, Lanneau G, Morrison JC.
with tertiary centres. A cross-sectional study of all women Postpartum hemorrhage after cesarean delivery: an analysis of risk factors.
who fulfilled the World Health Organization (WHO) criteria South Med J 2005;98:681–5.
for maternal near-miss or death in Tanzania showed that 7 Fawcus S, Moodley J. Postpartum haemorhage associated with caesarean
section and caesarean hysterectomy. Best Pract Res Clin Obstet Gynaecol
caesarean section complications were associated with 7.9% of 2013;27:233–49.
all maternal near-misses and 13% of maternal deaths. Life 8 Ekelund K, Hanke G, Stensballe J, Wikkelsøe A, Albrechtsen CK, Afshari A.
threatening caesarean section complications were three times Hemostatic resuscitation in postpartum hemorrhage - a supplement to
surgery. Acta Obstet Gynecol Scand 2015;94:680–92.
higher (relative risk of 3.2, 95% CI 1.5–6.6) at the regional 9 Sakinci M, Kuru O, Tosun M, Karagoz A, Celik H, Bildircin FD, Malatyalioglu
hospital compared with the university hospital.43 E. Clinical analysis of emergency peripartum hysterectomies in a tertiary
The health systems in these countries need to be centre. Clin Exp Obstet Gynecol 2014;41:654–8.
10 Smaill FM, Grivell RM. Antibiotic prophylaxis versus no prophylaxis for
strengthened to ensure that all women in genuine need of preventing infection after cesarean section. Cochrane Database Syst Rev
life-saving obstetric surgery have a safe caesarean section 2014;(10):CD007482.
while mechanisms are developed to discourage excessive use, 11 Ramanathran C, Penna L. Emergency Caesarean section. In: Chandraharan
E, Arulkumaran S, editors. Obstetric and Intrapartum Emergencies: A
which could result in added morbidity, no discernible Practical Guide to Management. Cambridge: Cambridge University Press;
benefits and pose a financial burden in resource- 2012.
poor countries.44 12 Wloch C, Wilson J, Lamagni T, Harrington P, Charlett A, Sheridan E. Risk
factors for surgical site infection following caesarean section in England:
results from a multicentre cohort study. BJOG 2012;119:1324–33.
13 Haas DM, Morgan S, Contreras K. Vaginal preparation with antiseptic
Conclusion solution before cesarean section for preventing postoperative infections.
Cochrane Database Syst Rev 2014;(12):CD007892.
Caesarean section is one of the most commonly performed 14 Mackeen AD, Berghella V, Larsen ML. Techniques and materials for skin
surgical procedures in the world. There are a variety of closure in caesarean section. Cochrane Database Syst Rev 2012;(11):
complications that may be uncommon but potentially very CD003577.
15 Antonelli E, Morales MA, Dumps P, Boulvain M, Weil A. Sonographic
serious when they occur. Obstetricians must operate with a detection of fluid collections and postoperative morbidity following
meticulous surgical technique and retain a high index of Cesarean section and hysterectomy. Ultrasound Obstet Gynecol
suspicion for complications, particularly visceral trauma, as 2004;23:388–92.
16 Mark KS, Alger L, Terplan M. Incisional negative pressure therapy to prevent
delayed recognition is associated with a significantly poorer wound complications following cesarean section in morbidly obese
outcome. Most complications will be recognised at the women: a pilot study. Surg Innov 2014;21:345–9.
17 Medhi R, Rai S, Das A, Ahmed M, Das B. Necrotizing fasciitis – a rare 34 Zeinali F, Stulberg JJ, Delaney CP. Pharmacological management of
complication following common obstetric operative procedures: report of postoperative ileus. Can J Surg 2009;52:153–7.
two cases. Int J Womens Health 2015;7:357–60. 35 Lord RVN, Sillin LF III. Motility Disorders of the Small Bowel. In: Bland KI,
18 Gungorduk K, Asicioglu O, Celikkol O, Sudolmus S, Ark C. Iatrogenic Sarr MG, B€ uchler MW, Csendes A, Garden OJ, Wong J, editors. General
bladder injuries during caesarean delivery: a case control study. J Obstet Surgery: Principles and International Practice. 2nd ed. London: Springer-
Gynecol 2010;30:667–70. Verlag London; 2009.
19 Phipps MG, Watabe B, Clemons JL, Weitzen S, Myers DL. Risk factors for 36 Latunde-Dada AO, Alleemudder DI, Webster DP. Ogilvie’s syndrome
bladder injury during cesarean delivery. Obstet Gynecol 2005;105:156–60. following caesarean section. BMJ Case Rep 2013; doi:10.1136/bcr-2013-
20 Tarneu CM. Bladder Injury During Cesarean Delivery. Curr Womens Health 010013.
Rev 2013;9:70–6. 37 Saha K, Newman E, Giles M, Horgan K. Ogilvie’s syndrome with caecal
21 Tai CK, Li SK, Hou SM, Fan CW. Bladder injury mimicking acute renal failure perforation after Caesarean section: a case report. J Med Case Rep
after cesarean section: a diagnostic challenge and minimally invasive 2009;3:6177.
management. Surg Laparosc Endosc Percutan Tech 2008;18:301–3. 38 Loudon JA, Groom KM, Hinkson L, Harrington D, Paterson-Brown S.
22 Patel BN, Gayer G. Imaging of Iatrogenic Complications of the Urinary Tract. Changing trends in operative delivery performed at full dilatation over a
Radiol Clin North Am 2014;52:1101–16. 10-year period. J Obstet Gynaecol 2010;30:370–5.
23 Rajasekar D, Hall M. Urinary tract injuries during obstetric intervention. Br J 39 Pergialiotis V, Vlachos DG, Rodolakis A, Haidopoulos D, Thomakos N,
Obstet Gynaecol 1997;104:731–4. Vlachos GD. First versus second stage C/S maternal and neonatal morbidity:
24 Mann WJ, Arato M, Patsner B, Stone ML. Ureteral injuries in an obstetrics a systematic review and meta-analysis. Eur J Obstet Gynecol Reprod Biol
and gynaecology training program: etiology and management. Obstet 2014;175:15–24.
Gynecol 1988;72:82–5. 40 National Institute for Health and Care Excellence. Insertion of a balloon
25 Yeong CT, Lim TL, Tan KH. Ureteral injuries in an obstetric and device to disimpact an engaged fetal head prior to emergency Caesarean
gynaecological teaching hospital. Med J Malaysia 1998;53:51–8. section. NICE interventional procedure guideline No. 515. Manchester:
26 Jha S, Coomarasamy A, Chan KK. Ureteric injury in obstetric and NICE, 2015.
gynaecological surgery. The Obstetrician & Gynaecologist 2004;6:203–8. 41 Vogel JP, Betran AP, Vindevoghel N, Souza JP, Torloni MR, Zhang J, et al.
27 Burks FN, Santucci RA. Management of iatrogenic ureteral injury. Ther Adv Use of the Robson classification to assess caesarean section trends in 21
Urol 2014;6:115–24. countries: a secondary analysis of two WHO multicountry surveys. Lancet
28 Ustunsoz B, Ugurel S, Duru NK, Ozgok Y, Ustunsoz A. Percutaneous Glob Health 2015;3:e260–70.
management of ureteral injuries that are diagnosed late after cesarean 42 Khan R, Blum LS, Sultana M, Bilkis S, Koblinsky M. An examination of
section. Korean J Radiol 2008;9:348–53. women experiencing obstetric complications requiring emergency care:
29 Royal College of Obstetricians and Gynaecologists. Caesarean Section. perceptions and sociocultural consequences of caesarean sections in
Consent Advice No. 7. London: RCOG; 2009. Bangladesh. J Health Popul Nutr 2012;30:159–71.
30 Stany MP, Farley JH. Complications of Gynecologic Surgery. Surg Clin North 43 Litorp H, Kidanto HL, R€ €st M, Abeid M, Nystr€
oo om L, Essen B. Maternal near-
Am 2008;88:343–59. miss and death and their association with caesarean section complications:
31 Papadopoulos VN, Michalopoulos A, Apostolidis S, Paramuthiotis D, a cross-sectional study at a university hospital and a regional hospital in
Ioannidis A, Mekras A, et al. Surgical management of colorectal injuries: Tanzania. BMC Pregnancy Childbirth 2014;14:244.
colostomy or primary repair? Tech Coloproctol 2011;15 Suppl 1:S63–6. 44 Gibbons L, Belizan JM, Lauer JA, Betran AP, Merialdi M, Althabe F. The
32 Paspulati RM, Dalal TA. Imaging of Complications Following Gynecologic Global Numbers and Costs of Additionally Needed and Unnecessary
Surgery. Radiographics 2010;30:625–43. Caesarean Sections Performed per Year: Overuse as a Barrier to Universal
33 Craciunas L, Sajid MS, Ahmed AS. Chewing gum in preventing Coverage. World Health Report. Background Paper No. 30. Geneva: WHO;
postoperative ileus in women undergoing caesarean section: a systematic 2010.
review and meta-analysis of randomised controlled trials. BJOG
2014;121:793–9.