2 ADVIA 360 560 Presentation 2016-06-09

Siemens Solutions for Hematology
ADVIA 360, ADVIA 560, and

ADVIA 560 AL Systems
Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved. Answers for life.
The ADVIA Hematology Family
Siemens can now offer a total solution with the

ADVIA® 360, ADVIA 560, ADVIA 560 AL and ADVIA 2120i Hematology
Systems.*
*Product availability varies by country
Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.
Page 2 2016-06-09 A91DX-HHS-150057-GC1-4A00 François Richir / BM / BA LD HH
Solutions for all laboratories of all sizes
Safe, reliable, easy to use
Accurate, comparable results
Siemens service and support
Underscores Siemens’ commitment to hematology

ADVIA 360 System Specifications
Throughput Up to 60 tests/hr
Parameters 22,* including 3-part WBC differential
Technology Impedance for CBC

Absorbance for HGB
Samples 100 mL sample volume
Closed- and open-tube manual modes
Reagents Three cyanide-free reagents
Quality Control Quality-control database

Levey-Jennings graphs
IT Storage capacity: 10,000 records

Easy-to-use multilingual user interface
HL7 connectivity
*OUS only; 18 parameters in the U.S.

Parameters 22, including 3-part WBC differential

17 kg
Technology Impedance for CBC
Absorbance for HGB 36 cm

IT Storage capacity: 10,000 records 49,2 cm

Easy-to-use multilingual user interface 31,6 cm
HL7 connectivity

ADVIA 360 System User Interface

Parameters 26,* including 5-part WBC Differential

Technology Laser light scatter for 5-part Differential
Impedance for CBC
Absorbance for HGB


HL7 connectivity *OUS only; 22 parameters in the U.S.

Parameters 26, including 5-part WBC Differential 52 cm

Impedance for CBC
Absorbance for HGB
35 kg

41 cm 49 cm
HL7 connectivity

ADVIA 560 AL System Specifications
Parameters 26, including 5-part WBC Differential

Impedance for CBC
Absorbance for HGB
Autoloader holds 100 samples (10 racks, 10 samples per rack)


HL7 connectivity

ADVIA 560 and ADVIA 560AL System User Interface
Start-up Screen Reagent Status Autoloader Log Result Screen

Quality Control on ADVIA 360 and ADVIA 560
Systems
QC Database and 24 QC files

Target values can be scanned

Manual Closed-Vial Sampling
Closed- or open-vial sampling
Suitable for various cap-pierceable

tubes
110 mL sample volume
Available on the ADVIA 360,560, and 560 AL Systems
Manual bar-code reader for positive sample ID

Tube management
• External Barcode Reader

Code 128; Code 39; Interleaved 2 of 5;
Codabar; EAN-8; EAN-13
• Supported Sample Tube Types

K2- or K3-EDTA 13 x 75-mm sample-tubes
- Sarstedt Monovette
- Becton Dickinson (BD) Vacutainer
- Terumo Venosafe …

Autoloader Upgrade on ADVIA 560 System

Reagents Setup
1. ADVIA 360/560 Dil

• Color Code GREEN
• Dilution of blood sample
• Sheat for optical
measurement
2. ADVIA 560 Lyse 5P

• Color code YELLOW
• Lyses RBCs and PLTs to
determine WBC count, 5-
diff and HGB concentration

Reagents Setup
3. ADVIA 560 Diff-5P

• Color code ORANGE
• Stop the lysing process and
prevent WBC from lysing

Reagents Setup
Reagents Lock System/Hardware

(HW) Key
• Each ADVIA 560 Lyse reagent

container comes with a reagent
HW key that contains 900
measurement credits
• System count down warns

operator when the remaining test
is 50

Reagents Setup
ADVIA 360
Function Diluent Lyse Cleaner Controls Calibration
ADVIA 360/560 ADVIA 360 ADVIA 360 Control Set ADVIA 360, 560
Product Name ADVIA 360 Lyse
Dil Cleaner (L-N-H) Calibrator
SMN 11170845 11170848 11170849 11170853 11170852
1 Ltr / 900
Content 20 Ltr 1 Ltr 2 x 3 x 3 mL 2 x 3 mL
tests
Consumption per
41 mL 1,1 mL 20 mL 110 µL 110 µL
measurement
Cycle 480 tests 900 tests 50 days 80 tests 80 tests

Open vial stability 60 days 90 days 90 days 14 days 7 days

Reagents Setup
ADVIA 560
Function Diluent Lyse Stopper HypoClean CC Controls Calibration
ADVIA 360/560 ADVIA 560 ADVIA 560 5P ADVIA 360,560 ADVIA 560 Control Set ADVIA 360, 560
Product Name
Dil Lyse Diff Hypoclean (L-N-H) Calibrator
SMN 11170845 11170846 11170847 11170851 11170854 11170852
5 Ltr / 900
Content 20 Ltr 1 Ltr 100 ml 2 x 3 x 3 mL 2 x 3 mL
tests
Consumption per
52 mL 5,7 mL 0,7 mL 4mL/jour 110 µL 110 µL
measurement
Cycles 380 tests 900 tests 1400 tests 25 days 80 tests 80 tests
Open vial stability 60 days 60 days 60 days 60 days 8 days 7 days

ADVIA 360 and 560 System Methodology
Technologies
Volumetric Impedance Determine the cellular concentration and volume distribution for
WBC, RBC and PLT. The unit is femtoliters (fL).
Photometric Measurement After RBC lysis, HGB concentration is measured based on

absorbance variation against blanc.The unit is g/dL.
Optical Measurement WBC analysis based on a dual-angle measure of light

scattering and diffraction. This determines cell volume and
granularity for each single cell

ADVIA 560 System Result Screen
The Diff cytogram has same orientation and color-coding

as the ADVIA 2120i System
X axis: complexity and granularity
Y axis: cell size
The baso cytogram
X axis: cell complexity
Y axis: cell size
Red cell and platelet histograms

X axis: cell size
Y axis: cell number

PLT RBC
PLT, MPV RBC, HGB, HCT,

MCV, MCH, MCHC,
RDWsd, RDWcv

DIFF BAS
NEU
MON
EOS BAS
LYM
Cellular
Cellular
Debris
Debris
WBC, NEU, LYM, BAS, BAS%

MON, EOS, NEU%,
LYM%, MON%,
EOS%

ADVIA 560 vs 2120i System Results (USA)

ADVIA 560 vs 2120i System Results (USA)
PLTS NEUTS LYMPHS
WBC HGB MCV

Operator Maintenance ?
Reduced Maintenance
Daily: System Shut Down (automatic)
Weekly: Na*
Monthly: Na*
On demand:
- Shear valve cleaning – 5 min
- Cleaning the Wash head – 5 min
- Measuring chambers – 1 min

ADVIA 560, ADVIA 560AL, and ADVIA 360 Systems
• Small footprint with onboard cleaning and zero daily maintenance

• Good reliability
• Full support supplied by Siemens

Siemens Scalable Hematology Systems to
Suit Every laboratory*
Core
Siemens Range of Satellite Low Medium High Backup
STAT Labs Automation
Hematology Systems* Labs Workload Workload Workload Systems
Lab
HemaPrep Device ü ü ü ü ü
Diff-Quick Stain Kit ü
®
Hematek 3000 System ü ü ü ü
ADVIA 360 System ü ü ü ü
Note: CellaVision is a trademark of CellaVision AB.

ADVIA 560 System ü ü ü
ADVIA 560AL System ü ü
®
CellaVision Image Capture System ü
CellaVision DM1200 ü ü
CellaVision DM9600 ü ü
ADVIA 2120i System ü ü
ADVIA Autoslide ü ü
Aptio™ Automation ü
Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved. *Product availability varies by country.
Meeting Requirements
Your Requirements ADVIA Hematology Family

A range of systems to meet future demands A range of upgradeable systems
Compatible LIS or middleware systems HL7 LIS or middleware connectivity
Opportunities for Automation and satellite Siemens can provide multidisciplinary
solutions Automation plus satellite packages
Protection from exposure to biohazards All systems provide closed vial sampling
Potential of digital microscopy All CellaVision systems are available
Confidence that systems are easy to use Systems can be used by all skill levels
Fully supported systems Siemens provides full-service support
A single supplier providing a total solution Siemens can provide a comprehensive
solution to meet all your requirements
For more information contact:
François Richir
BM Hematology
francois.richir@siemens.com


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Siemens Solutions for Hematology

ADVIA 360, ADVIA 560, and

Siemens can now offer a total solution with the

The ADVIA Hematology Family

Solutions for all laboratories of all sizes

Safe, reliable, easy to use

Accurate, comparable results

Siemens service and support

Underscores Siemens’ commitment to hematology

Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.

Parameters 22,* including 3-part WBC differential

Technology Impedance for CBC

Reagents Three cyanide-free reagents

Quality Control Quality-control database

IT Storage capacity: 10,000 records

Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.

Parameters 22, including 3-part WBC differential

Reagents Three cyanide-free reagents

Quality Control Quality-control database

IT Storage capacity: 10,000 records 49,2 cm

Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.

Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.

Parameters 26,* including 5-part WBC Differential

Reagents Three cyanide-free reagents

Quality Control Quality-control database

IT Storage capacity: 100,000 records

Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.

Parameters 26, including 5-part WBC Differential 52 cm

Reagents Three cyanide-free reagents

Quality Control Quality-control database

Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.

Parameters 26, including 5-part WBC Differential

Reagents Three cyanide-free reagents

Quality Control Quality-control database

IT Storage capacity: 100,000 records

Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.

Start-up Screen Reagent Status Autoloader Log Result Screen

Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.

QC Database and 24 QC files

Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.

Closed- or open-vial sampling

Suitable for various cap-pierceable

Available on the ADVIA 360,560, and 560 AL Systems

Manual bar-code reader for positive sample ID

Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.

• External Barcode Reader

• Supported Sample Tube Types

Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.

Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.

1. ADVIA 360/560 Dil

2. ADVIA 560 Lyse 5P

Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.

3. ADVIA 560 Diff-5P

Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.

Reagents Lock System/Hardware

• Each ADVIA 560 Lyse reagent

• System count down warns

Unrestricted © Siemens Healthcare Diagnostics Inc. 2015 All rights reserved.