GUJARAT TECHNOLOGICAL UNIVERSITY

Bachelor of Pharmacy
Subject Code: BP501TT
SEMESTER: V
Subject Name: Medicinal Chemistry II

Scope: This subject is designed to impart fundamental knowledge on the structure, chemistry and
therapeutic value of drugs. The subject emphasizes on structure activity relationships of drugs,
importance of physicochemical properties and metabolism of drugs. The syllabus also emphasizes on
chemical synthesis of important drugs under each class.

Objectives: Upon completion of the course the student shall be able to

1. Understand the chemistry of drugs with respect to their pharmacological activity
2. Understand the drug metabolic pathways, adverse effect and therapeutic value of drugs
3. Know the Structural Activity Relationship of different class of drugs
4. Study the chemical synthesis of selected drugs

Teaching scheme and examination scheme:

Teaching Scheme Evaluation Scheme

Theory Tutorial Practical Total Theory Practical
External Internal External Internal
3 1 0 4 80 20 0 0

Sr No Topics %
weightage
1. Antihistaminic agents: Histamine, receptors and their distribution in the human 10
body
H1–antagonists: Diphenhydramine hydrochloride*, Dimenhydrinate,
Doxylamines cuccinate, Clemastine fumarate, Diphenylphyraline
hydrochloride, Tripelenamine hydrochloride, Chlorcyclizine hydrochloride,
Meclizine hydrochloride, Buclizine hydrochloride, Chlorpheniramine maleate,
Triprolidine hydrochloride*, Phenidamine tartarate, Promethazine
hydrochloride*, Trimeprazine tartrate, Cyproheptadine hydrochloride,
Azatidine maleate, Astemizole, Loratadine, Cetirizine, Levocetrazine Cromolyn
sodium
H2-antagonists: Cimetidine*, Famotidine, Ranitidin
Gastric Proton pump inhibitors: Omeprazole, Lansoprazole, Rabeprazole,
Pantoprazole
Anti-neoplastic agents:
Alkylating agents: Meclorethamine*, Cyclophosphamide, Melphalan
Chlorambucil, Busulfan, Thiotepa
Antimetabolites: Mercaptopurine*, Thioguanine, Fluorouracil, Floxuridine,
Cytarabine, Methotrexate*, Azathioprine
Antibiotics: Dactinomycin, Daunorubicin, Doxorubicin, Bleomycin
Plant products: Etoposide, Vinblastin sulphate, Vincristin sulphate
Miscellaneous: Cisplatin, Mitotane
2. Anti-anginal: 10
Vasodilators: Amyl nitrite, Nitroglycerin*, Pentaerythritol tetranitrate,
Isosorbide dinitrite*, Dipyridamole
Calcium channel blockers: Verapamil, Bepridil hydrochloride, Diltiazem
hydrochloride, Nifedipine, Amlodipine, Felodipine, Nicardipine, Nimodipine.
Diuretics:
Carbonic anhydrase inhibitors: Acetazolamide*, Methazolamide,
Dichlorphenamide. Thiazides: Chlorthiazide*, Hydrochlorothiazide,
Hydroflumethiazide, Cyclothiazide, Loop diuretics: Furosemide*, Bumetanide,

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 GUJARAT TECHNOLOGICAL UNIVERSITY
Bachelor of Pharmacy
Subject Code: BP501TT
Ethacrynic acid. Potassium sparing Diuretics: Spironolactone, Triamterene,
Amiloride. Osmotic Diuretics: Mannitol
Anti-hypertensive Agents: Timolol, Captopril, Lisinopril, Enalapril,
Benazepril hydrochloride, Quinapril hydrochloride, Methyldopate
hydrochloride,* Clonidine hydrochloride, Guanethidine monosulphate,
Guanabenz acetate, Sodium nitroprusside, Diazoxide,Minoxidil, Reserpine,
Hydralazine hydrochloride.
3. Anti-arrhythmic Drugs: Quinidine sulphate, Procainamide hydrochloride, 10
Disopyramide phosphate*, Phenytoin sodium, Lidocaine hydrochloride,
Tocainide hydrochloride, Mexiletine hydrochloride, Lorcainide hydrochloride,
Amiodarone, Sotalol.
Anti-hyperlipidemic agents: Clofibrate, Lovastatin, Cholesteramine and
Cholestipol
Coagulant & Anticoagulants: Menadione, Acetomenadione, Warfarin*,
Anisindione, clopidogrel
Drugs used in Congestive Heart Failure: Digoxin, Digitoxin, Nesiritide,
Bosentan, Tezosentan.
Drugs acting on Endocrine system 8
4. Nomenclature, Stereochemistry and metabolism of steroids
Sex hormones: Testosterone, Nandralone, Progestrones, Oestriol, Oestradiol,
Oestrione, Diethyl stilbestrol.
Drugs for erectile dysfunction: Sildenafil, Tadalafil.
Oral contraceptives: Mifepristone, Norgestril, Levonorgestrol
Corticosteroids: Cortisone, Hydrocortisone, Prednisolone, Betamethasone,
Dexamethasone
Thyroid and antithyroid drugs: L-Thyroxine, L-Thyronine, Propylthiouracil,
Methimazole.
5. Antidiabetic agents: 7
Insulin and its preparations Sulfonyl ureas: Tolbutamide*, Chlorpropamide,
Glipizide, Glimepiride. Biguanides: Metformin. Thiazolidinediones:
Pioglitazone, Rosiglitazone. Meglitinides: Repaglinide, Nateglinide.
Glucosidase inhibitors: Acrabose, Voglibose.
Local Anesthetics: SAR of Local anesthetics
Benzoic Acid derivatives; Cocaine, Hexylcaine, Meprylcaine,
Cyclomethycaine, Piperocaine.
Amino Benzoic acid derivatives: Benzocaine*, Butamben, Procaine*,
Butacaine, Propoxycaine, Tetracaine, Benoxinate.
Lidocaine/Anilide derivatives: Lignocaine, Mepivacaine, Prilocaine,
Etidocaine.
Miscellaneous: Phenacaine, Diperodon, Dibucaine.*
Study of the development of the following classes of drugs, Classification, mechanism of action, uses of
drugs mentioned in the course, Structure activity relationship of selective class of drugs as specified in the
course and synthesis of drugs superscripted (*)
Recommended Books (Latest Editions)
1. Wilson and Giswold’s Organic medicinal and Pharmaceutical Chemistry.
2. Foye’s Principles of Medicinal Chemistry.
3. Burger’s Medicinal Chemistry, Vol I to IV.
4. Introduction to principles of drug design- Smith and Williams.
5. Remington’s Pharmaceutical Sciences.
6. Martindale’s extra pharmacopoeia.
7. Organic Chemistry by I.L. Finar, Vol. II.
8. The Organic Chemistry of Drug Synthesis by Lednicer, Vol. 1to 5.
9. Indian Pharmacopoeia.
10. Text book of practical organic chemistry- A.I.Vogel.

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 GUJARAT TECHNOLOGICAL UNIVERSITY
Bachelor of Pharmacy
Subject Code: BP502TP
SEMESTER: V
Subject Name: Pharmacology II

Scope: This subject is intended to impart the fundamental knowledge on various aspects (classification,
mechanism of action, therapeutic effects, clinical uses, side effects and contraindications) of drugs acting
on different systems of body and in addition,emphasis on the basic concepts of bioassay.

Objectives: Upon completion of the course the student shall be able to

1. Understand the mechanism of drug action and its relevance in the treatment of different diseases
2. Demonstrate isolation of different organs/tissues from the laboratory animals by simulated
experiments
3. Demonstrate the various receptor actions using isolated tissue preparation
4. Appreciate correlation of pharmacology with related medical sciences

Teaching scheme and examination scheme:

Teaching Scheme Evaluation Scheme

Theory Tutorial Practical Total Theory Practical
External Internal External Internal
3 1 4 6 80 20 80 20

Sr No Topics %
weightage
1. Pharmacology of drugs acting on cardio vascular system 10
a. Introduction to hemodynamic and electrophysiology of heart.
b. Drugs used in congestive heart failure
c. Anti-hypertensive drugs.
d. Anti-anginal drugs.
e. Anti-arrhythmic drugs.
f. Anti-hyperlipidemic drugs.
2. Pharmacology of drugs acting on cardio vascular system 10
a. Drug used in the therapy of shock.
b. Hematinics, coagulants and anticoagulants.
c. Fibrinolytics and anti-platelet drugs
d. Plasma volume expanders
2. Pharmacology of drugs acting on urinary system
a. Diuretics
b. Anti-diuretics.
3. Autocoids and related drugs 10
a. Introduction to autacoids and classification
b. Histamine, 5-HT and their antagonists.
c. Prostaglandins, Thromboxanes and Leukotrienes.
d. Angiotensin, Bradykinin and Substance P.
e. Non-steroidal anti-inflammatory agents
f. Anti-gout drugs
g. Antirheumatic drugs
Pharmacology of drugs acting on endocrine system 8
4. a. Basic concepts in endocrine pharmacology.
b. Anterior Pituitary hormones- analogues and their inhibitors.
c. Thyroid hormones- analogues and their inhibitors.
d. Hormones regulating plasma calcium level- Parathormone, Calcitonin and
Vitamin-D.

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 GUJARAT TECHNOLOGICAL UNIVERSITY
Bachelor of Pharmacy
Subject Code: BP502TP
d. Insulin, Oral Hypoglycemic agents and glucagon.
e. ACTH and corticosteroids.
5. Pharmacology of drugs acting on endocrine system 7
a. Androgens and Anabolic steroids.
b. Estrogens, progesterone and oral contraceptives.
c. Drugs acting on the uterus
Bioassay
a. Principles and applications of bioassay.
b.Types of bioassay
c. Bioassay of insulin, oxytocin, vasopressin, ACTH,d-tubocurarine,digitalis,
histamine
and 5-HT

Practical
1.Introduction to in-vitro pharmacology and physiological salt solutions.
2.Effect of drugs on isolated frog heart.
3.Effect of drugs on blood pressure and heart rate of dog.
4.Study of diuretic activity of drugs using rats/mice.
5.DRC of acetylcholine using frog rectus abdominis muscle.
6.Effect of physostigmine and atropine on DRC of acetylcholine using frog rectus
1.abdominis muscle and rat ileum respectively.
7.Bioassay of histamine using guinea pig ileum by matching method.
8.Bioassay of oxytocin using rat uterine horn by interpolation method.
9.Bioassay of serotonin using rat fundus strip by three point bioassay.
10.
Bioassay of acetylcholine using rat ileum/colon by four point bioassay.
11.
Determination of PA2 value of prazosin using rat anococcygeus muscle (by Schilds plot
method).
12. Determination of PD2 value using guinea pig ileum.
13. Effect of spasmogens and spasmolytics using rabbit jejunum.
14. Anti-inflammatory activity of drugs using carrageenan induced paw-edema model.
15. Analgesic activity of drug using central and peripheral methods
Note: All laboratory techniques and animal experiments are demonstrated by simulated
experiments by softwares and videos

Recommended Books (Latest Editions)

1. Rang H. P., Dale M. M., Ritter J. M., Flower R. J., Rang and Dale’s Pharmacology, Churchil
Livingstone Elsevier
2. Katzung B. G., Masters S. B., Trevor A. J., Basic and clinical pharmacology, Tata McGraw-Hill
3. Goodman and Gilman’s, The Pharmacological Basis of Therapeutics
4. Marry Anne K. K., Lloyd Yee Y., Brian K. A., Robbin L.C., Joseph G. B., Wayne A. K.,
Bradley R.W., Applied Therapeutics, The Clinical use of Drugs, The Point Lippincott Williams
& Wilkins
5. Mycek M.J, Gelnet S.B and Perper M.M. Lippincott’s Illustrated Reviews Pharmacology
6. K.D.Tripathi. Essentials of Medical Pharmacology, , JAYPEE Brothers Medical Publishers (P)
Ltd, New Delhi
7. Sharma H. L., Sharma K. K., Principles of Pharmacology, Paras medical publisher
8. Modern Pharmacology with clinical Applications, by Charles R.Craig& Robert
9. Ghosh MN. Fundamentals of Experimental Pharmacology. Hilton & Company Kolkata.
10. Kulkarni SK. Handbook of experimental pharmacology. Vallabh Prakashan

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 GUJARAT TECHNOLOGICAL UNIVERSITY
Bachelor of Pharmacy
Subject Code: BP503TP
SEMESTER: V
Subject Name: Pharmacognosy and Phytochemistry II

Scope: The main purpose of subject is to impart the students the knowledge of how the
secondary metabolites are produced in the crude drugs, how to isolate and identify and
produce them industrially. Also this subject involves the study of producing the plants and
phytochemicals through plant tissue culture, drug interactions and basic principles of
traditional system of medicine.

Objectives: Upon completion of the course the student shall be able to

1. to know the modern extraction techniques, characterization and identification of the herbal drugs
and phytoconstituents
2. to understand the preparation and development of herbal formulation
3. to understand the herbal drug interactions
4. to carryout isolation and identification of phytoconstituents
5.
Teaching scheme and examination scheme:

Teaching Scheme Evaluation Scheme

Theory Tutorial Practical Total Theory Practical
External Internal External Internal
3 1 4 6 80 20 80 20

Sr No Topics %
weightage
1. Metabolic pathways in higher plants and their determination 7
a) Brief study of basic metabolic pathways and formation of different secondary
metabolites through these pathways- Shikimic acid pathway, Acetate pathways
and Amino acid pathway.
b) Study of utilization of radioactive isotopes in the investigation of Biogenetic
studies.
2. General introduction, composition, chemistry & chemical classes, biosources, 14
therapeutic uses and commercial applications of following secondary
metabolites:
Alkaloids: Vinca, Rauwolfia, Belladonna, Opium,
Phenylpropanoids and Flavonoids: Lignans, Tea, Ruta
Steroids, Cardiac Glycosides & Triterpenoids: Liquorice, Dioscorea,
Digitalis
Volatile oils: Mentha, Clove, Cinnamon, Fennel, Coriander,
Tannins: Catechu, Pterocarpus
Resins: Benzoin, Guggul, Ginger, Asafoetida, Myrrh, Colophony
Glycosides: Senna, Aloes, Bitter Almond
Iridoids, Other terpenoids & Naphthaquinones: Gentian, Artemisia, taxus,
carotenoids
3. Isolation, Identification and Analysis of Phytoconstituents 6
a) Terpenoids: Menthol, Citral, Artemisin
b) Glycosides: Glycyrhetinic acid & Rutin
c) Alkaloids: Atropine,Quinine,Reserpine,Caffeine
d) Resins: Podophyllotoxin, Curcumin
Industrial production, estimation and utilization of the following 10
4. phytoconstituents: Forskolin, Sennoside, Artemisinin, Diosgenin, Digoxin,
Atropine, Podophyllotoxin, Caffeine, Taxol, Vincristine and Vinblastine

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 GUJARAT TECHNOLOGICAL UNIVERSITY
Bachelor of Pharmacy
Subject Code: BP503TP
5. Basics of Phytochemistry 8
Modern methods of extraction, application of latest techniques like
Spectroscopy, chromatography and electrophoresis in the isolation, purification
and identification of crude drugs.

Practical List:
1. Morphology, histology and powder characteristics & extraction & detection of: Cinchona,
Cinnamon, Senna, Clove, Ephedra, Fennel and Coriander
2. Exercise involving isolation & detection of active principles
a. Caffeine - from tea dust.
b. Diosgenin from Dioscorea
c. Atropine from Belladonna
d. Sennosides from Senna
3. Separation of sugars by Paper chromatography
4. TLC of herbal extract
5. Distillation of volatile oils and detection of phytoconstitutents by TLC
6. Analysis of crude drugs by chemical tests: (i) Asafoetida (ii) Benzoin (iii) Colophony (iv) Aloes
(v) Myrrh

Recommended Books: (Latest Editions)

1. W.C.Evans, Trease and Evans Pharmacognosy, 16th edition, W.B. Sounders & Co., London,
2009.
2. Mohammad Ali. Pharmacognosy and Phytochemistry, CBS Publishers & Distribution, New
Delhi.
3. Text book of Pharmacognosy by C.K. Kokate, Purohit, Gokhlae (2007), 37th Edition, Nirali
Prakashan, New Delhi.
4. Herbal drug industry by R.D. Choudhary (1996), Ist Edn, Eastern Publisher, New Delhi.
5. Essentials of Pharmacognosy, Dr.SH.Ansari, IInd edition, Birla publications, New Delhi,
2007
6. Herbal Cosmetics by H.Pande, Asia Pacific Business press, Inc, New Delhi.
7. A.N. Kalia, Textbook of Industrial Pharmacognosy, CBS Publishers, New Delhi, 2005.
8. R Endress, Plant cell Biotechnology, Springer-Verlag, Berlin, 1994.
9. Pharmacognosy & Pharmacobiotechnology. James Bobbers, Marilyn KS, VE Tylor.
10. The formulation and preparation of cosmetic, fragrances and flavours.
11. Remington’s Pharmaceutical sciences.
12. Text Book of Biotechnology by Vyas and Dixit.
13. Text Book of Biotechnology by R.C. Dubey.

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 GUJARAT TECHNOLOGICAL UNIVERSITY
Bachelor of Pharmacy
Subject Code: BP501TT
SEMESTER: V
Subject Name: Pharmaceutical Microbiology

Scope: Study of all categories of microorganisims especially for the production of alchol antibiotics,
vaccines, vitamins enzymes etc...

Objectives: Upon completion of the course the student shall be able to

1. Understand methods of identification, cultivation and preservation of various microorganisms
2. To understand the importance and implementation of sterlization in pharmaceutical processing
and industry
3. Learn sterility testing of pharmaceutical products.
4. Carried out microbiological standardization of Pharmaceuticals.
5. Understand the cell culture technology and its applications in pharmaceutical industries.

Teaching scheme and examination scheme:

Teaching Scheme Evaluation Scheme

Theory Tutorial Practical Total Theory Practical
External Internal External Internal
3 1 4 6 80 20 80 20

Sr No Topics %
weightage
1. Introduction, history of microbiology, its branches, scope and its importance. 10
Introduction to Prokaryotes and Eukaryotes : Study of ultra-structure and
morphological classification of bacteria, nutritional requirements, raw materials
used for culture media and physical parameters for growth, growth curve,
isolation and preservation methods for pure cultures, cultivation of anaerobes,
quantitative measurement of bacterial growth (total & viable count). Study of
different types of phase constrast microscopy, dark field microscopy and
electron microscopy
2. Identification of bacteria using staining techniques (simple, Gram’s &Acid fast 10
staining) and biochemical tests (IMViC).
Study of principle, procedure, merits, demerits and applications of physical,
chemical gaseous,radiation and mechanical method of sterilization. Evaluation
of the efficiency of sterilization methods. Equipments employed in large scale
sterilization. Sterility indicators.
3. Study of morphology, classification, reproduction/replication and cultivation of 10
Fungi and Viruses. Classification and mode of action of disinfectants Factors
influencing disinfection, antiseptics and their evaluation. For bacteriostatic and
bactericidal actions. Evaluation of bactericidal & Bacteriostatic.
Sterility testing of products (solids, liquids, ophthalmic and other sterile
products) according to IP, BP and USP.
Designing of aseptic area, laminar flow equipments; study of different sources 8
4. of contamination in an aseptic area and methods of prevention, clean area
classification.
Principles and methods of different microbiological assay. Methods for
standardization of antibiotics, vitamins and amino acids. Assessment of a new
antibiotic.
5. Types of spoilage, factors affecting the microbial spoilage of pharmaceutical 7
products, sources and types of microbial contaminants, assessment of microbial
contamination and spoilage. Preservation of pharmaceutical products using
antimicrobial agents, evaluation of microbial stability of formulations.

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 GUJARAT TECHNOLOGICAL UNIVERSITY
Bachelor of Pharmacy
Subject Code: BP501TT
Growth of animal cells in culture, general procedure for cell culture, Primary,
established and transformed cell cultures. Application of cell cultures in
pharmaceutical industry and research.

Practical List
1. Introduction and study of different equipments and processing, e.g., B.O.D. incubator, laminar flow,
aseptic hood, autoclave, hot air sterilizer, deep freezer, refrigerator, microscopes used in experimental
microbiology.
2. Sterilization of glassware, preparation and sterilization of media.
3. Sub culturing of bacteria and fungus. Nutrient stabs and slants preparations.
4. Staining methods- Simple, Grams staining and acid fast staining (Demonstration with practical).
5. Isolation of pure culture of micro-organisms by multiple streak plate technique and other techniques.
6. Microbiological assay of antibiotics by cup plate method and other methods
7. Motility determination by Hanging drop method.
8. Sterility testing of pharmaceuticals.
9. Bacteriological analysis of water
10. Biochemical test.

Recommended books: (Latest Edition)

1. W.B. Hugo and A.D. Russel: Pharmaceutical Microbiology, Blackwell Scientific publications, Oxford
London.
2. Prescott and Dunn., Industrial Microbiology, 4th edition, CBS Publishers & Distributors, Delhi
3. Pelczar, Chan Kreig, Microbiology, Tata McGraw Hill edn.
4. Malcolm Harris, Balliere Tindall and Cox: Pharmaceutical Microbiology.
5. Rose: Industrial Microbiology.
6. Probisher, Hinsdill et al: Fundamentals of Microbiology, 9th ed. Japan
7. Cooper and Gunn’s: Tutorial Pharmacy, CBS Publisher and Distribution.
8. Peppler: Microbial Technology.
9. I.P., B.P., U.S.P.- latest editions.
10. Ananthnarayan : Text Book of Microbiology, Orient-Longman, Chennai
11. Edward: Fundamentals of Microbiology.
12. N.K.Jain: Pharmaceutical Microbiology, Vallabh Prakashan, Delhi
13. Bergeys manual of systematic bacteriology, Williams and Wilkins- A Waverly company

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 GUJARAT TECHNOLOGICAL UNIVERSITY
Bachelor of Pharmacy
Subject Code: BP505TT
SEMESTER: V
Subject Name: Pharmaceutical Biotechnology

Scope:
 Biotechnology has a long promise to revolutionize the biological sciences and technology.
 Scientific application of biotechnology in the field of genetic engineering, medicine and
fermentation technologymakes the subject interesting.
 Biotechnology is leading to new biological revolutions in diagnosis, prevention and cure of
diseases, new and cheaper pharmaceutical drugs.
 Biotechnology has already produced transgenic crops and animals and the future promises lot
more.
 It is basically a research-based subject.

Objectives: Upon completion of the course the student shall be able to

1. Understanding the importance of Immobilized enzymes in Pharmaceutical Industries
2. Genetic engineering applications in relation to production of pharmaceuticals
3. Importance of Monoclonal antibodies in Industries
4. Appreciate the use of microorganisms in fermentation technology

Teaching scheme and examination scheme:

Teaching Scheme Evaluation Scheme

Theory Tutorial Practical Total Theory Practical
External Internal External Internal
3 1 0 4 80 20 0 0

Sr No Topics %
weightage
1. a) Brief introduction to Biotechnology with reference to Pharmaceutical 10
Sciences.
b) Enzyme Biotechnology- Methods of enzyme immobilization and
applications.
c) Biosensors- Working and applications of biosensors in Pharmaceutical
Industries.
d) Brief introduction to Protein Engineering.
e) Use of microbes in industry. Production of Enzymes- General consideration
-Amylase, Catalase, Peroxidase, Lipase, Protease, Penicillinase.
f) Basic principles of genetic engineering.
2. a) Study of cloning vectors, restriction endonucleases and DNA ligase. 10
b) Recombinant DNA technology. Application of genetic engineering in
medicine.
c) Application of r DNA technology and genetic engineering in the production
of:i) Interferon ii) Vaccines- hepatitis- B iii) Hormones-Insulin.
d) Brief introduction to PCR
3. Types of immunity- humoral immunity, cellular immunity 10
a) Structure of Immunoglobulins
b) Structure and Function of MHC
c) Hypersensitivity reactions, Immune stimulation and Immune suppressions.
d) General method of the preparation of bacterial vaccines, toxoids, viral
vaccine,antitoxins, serum-immune blood derivatives and other products relative
to immunity.
e) Storage conditions and stability of official vaccines

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 GUJARAT TECHNOLOGICAL UNIVERSITY
Bachelor of Pharmacy
Subject Code: BP505TT
f) Hybridoma technology- Production, Purification and Applications
g) Blood products and Plasma Substituties.
a) Immuno blotting techniques- ELISA, Western blotting, Southern blotting. 8
4. b) Genetic organization of Eukaryotes and Prokaryotes
c) Microbial genetics including transformation, transduction, conjugation,
plasmids and transposons.
d) Introduction to Microbial biotransformation and applications.
e) Mutation: Types of mutation/mutants.
5. a) Fermentation methods and general requirements, study of media, equipments, 7
sterilization methods, aeration process, stirring.
b) Large scale production fermenter design and its various controls.
c) Study of the production of - penicillins, citric acid, Vitamin B12, Glutamic
acid, Griseofulvin,
d) Blood Products: Collection, Processing and Storage of whole human blood,
dried human plasma, plasma Substituties.

Recommended Books (Latest edition):

1. B.R. Glick and J.J. Pasternak: Molecular Biotechnology: Principles and Applications of
Recombinant DNA: ASM Press Washington D.C.
2. RA Goldshy et. al., : Kuby Immunology.
3. J.W. Goding: Monoclonal Antibodies.
4. J.M. Walker and E.B. Gingold: Molecular Biology and Biotechnology by Royal Society of
Chemistry.
5. Zaborsky: Immobilized Enzymes, CRC Press, Degraland, Ohio.
6. S.B. Primrose: Molecular Biotechnology (Second Edition) Blackwell Scientific Publication.
7. Stanbury F., P., Whitakar A., and Hall J., S., Principles of fermentation technology, 2nd edition,
Aditya books Ltd., New Delhi

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