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IAH AC Introduction To Homotoxicology

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Introduction to Homotoxicology

IAH AC Introduction to Homotoxicology

© IAH 2007

Homotoxicology, developed by the German doctor Hans-Heinrich Reckeweg, is


the scientific concept behind antihomotoxic medicine. It is a different way of
approaching the patient and his disease.

In regular medicine the concept of the ‘terrain of the patient’ is not known and
therefore it often looks as if the patient is purely treated according to the
symptoms he presents.

1
Objectives

• To understand the basic principles of homotoxicology


• Disease and health
• The homotoxin
• The origin and history of the six phase table
• The dynamic of a disease in the six phase table
• The principle of disease evolution

© IAH 2007 2

Many aspects in antihomotoxic medicine is different from regular medicine.


Although the same terminology is often used, other matters are meant. Therefore
it is important to well understand what disease and health means in
homotoxicology.

In homotoxicology the causes of disease are seen as the homotoxins. Therefore


we should be able to define them. More specific information on homotoxins can
be found in the lecture ‘IAH AC Homotoxins’

As we will see in detail in other lectures the Disease Evolution Table (DET) is a
dynamic instrument to evaluate the evolution of the disease of the patient. It is an
essential instrument in the antihomotoxic approach of the patient. The fact that in
time the patient will evolve or the type of his disease will change on the table is
extremely important as it will direct our decision how to treat the patient and what
medication is appropriate to do so in a correct homotoxicological way

2
The father of Homotoxicology:
Dr. H-H Reckeweg

© IAH 2007

Dr. Hans-Heinrich Reckeweg was the father of Homotoxicology. Due to his


immense work and publications homotoxicology became a worldwide
disseminated approach in medicine. Not only the theory, but also the daily use of
antihomotoxic medications is present in more than 70 countries all over the world.
Today experts in homotoxicology worldwide do further research in this matter and
made out of homotoxicology an acceptable approach in modern medicine

Dr. Reckeweg’s conviction brought many medical doctors to treat their patients in
a different way. Still now, and even more, more than 20 years after his death,
homotoxicology is a well appreciated concept in complementary medicine and
becomes more and more an eye opener in conventional medicine. In this way,
Dr. Reckeweg succeeded to accomplish his dream: to built a bridge between
conventional and complementary medicine.

3
“I would like one day to merge homeopathy with
mainstream medicine”

H.-H. Reckeweg 1905-1985

© IAH 2007 4

As indeed, homotoxicology is a very understandable concept, for the


complementary medicine practitioner as well as for the conventional medicine
doctor. Even though it sometimes seems as if both kinds of medicine are
opposite, today we see that conventional trained MD’s are more and more open
for antihomotoxic medicine and homeopaths are less strictly bound to classical
singular remedy medicine. This is due to the advances in molecular biology which
makes the working mechanism of antihomotoxic medicine more apparent.

Dr. Reckeweg indeed did build a bridge between conventional and


complementary medicine and by this created an integrative platform in medicine
that finds its way easily into daily medical practice.

4
What is Homotoxicology?

© IAH 2007

Let us study now the basic principles of homotoxicology more in depth. What is
homotoxicology and in which way does it deviates from the conventional medical
approach of the patient and his disease?

5
HOMO TOXICO LOGY

Human Toxin Study

© IAH 2007 6

The term Homotoxicology is derived from three words ; “homo” meaning man,
“toxico” derived from toxin or poison, and finally “logy”, derived from the Greek
‘logos’, meaning study.
To summarize, we can describe Homotoxicology as the study of the influence of
toxic substances on humans.

6
Homotoxicology is the study of the
influence of homotoxins on the
human organism.

Homotoxicology is a bridge between


complementary and conventional
medicine

© IAH 2007

In homotoxicology we study the way the presence of homotoxins will influence


the functions of the cell and by this the function of the whole human organism.
The reaction or rigidity of the defense mechanism against the homotoxin will
define the clinical status the patient is in. Symptoms are an expression of the
body’s effort to get away with the toxins.

As the approach in homotoxicology remains clinical, research has been done on


the mode of action of this type of medications. Homotoxicology is very relied to
conventional medicine and very acceptable for ‘open minded’ conventional
medical doctors as the working mechanisms behind antihomotoxic medication
can be explained in terms of the molecular biological models of this conventional
medicine. On the other hand, and this in contrast to conventional medications,
most antihomotoxic medications contain a micro doses or even nano doses of
active components and are therefore non-toxic. Few side effects and contra-
indications, no interactions with other medications, safe and effective, classify
homotoxicology to complementary ‘gentle’ medicine. In this way homotoxicology
is building a bridge between both conventional and complementary medicine.
The bridge refers to the strong conventional medical diagnosis and the gentle,
non toxic treatment of complementary medicine.

7
Homotoxicological definition of illness

• Diseases are the expression of biologically purposeful defense


mechanisms against endogenous and exogenous homotoxins,
or the expression of the organism’s effort to compensate for
toxic damage it has sustained.

© IAH 2007 8

From a homotoxicological point of view, illness is caused by the body’s reaction


to the presence of disruptive homotoxins. What we recognize as the clinical
symptoms of illness is what surfaces after the defense system has reacted to the
threat.
This means that illness is not the presence of symptoms as such, since these
should only be seen as proof of ongoing defense activity.
As long as clinical symptoms are only viewed as a threat to the quality of life of
the patient and the entire treatment is geared to the removal of these symptoms,
the results will be superficial and we are actually mortgaging the patient’s long-
term health.
A biotherapeutic treatment takes into account the causative homotoxins and, by
stimulating the body’s own defense system, will affect the actual causes of the
illness. Biotherapy is always a regulation therapy, and never a suppression
therapy.

8
Homotoxicological definition of illness

• Diseases are the expression of biologically purposeful defense


mechanisms against endogenous and exogenous homotoxins,
or the expression of the organism’s effort to compensate for
toxic damage it has sustained.

© IAH 2007 9

Expression : What we see is not what we get. The symptoms are only the result
of a defense activity of the organism against toxic burdens. If for example an
inflammation is there, causal treatment means that we will have to do something
about the inflammation triggering homotoxins, which can be done by the
regulation of the defense activity. Just a suppression of the symptoms is
comparable with pushing an iceberg under the water, hoping that it will never
appear again. Stopping the pushing will make the iceberg reappear. This
phenomenon explains the recurrence of diseases in conventional medicine.
Another comparison can be made. Clinical symptoms are only an expression of
something deeper like the words someone speaks are only an expression of his
thoughts. Suppression of words, a ban on speaking, can never change the cause
of talking, which are the thoughts in the mind of the speaker. Treatment of the
mind, as in psychotherapy, will automatically result in different expressions.
In the same way the suppression of fever in viral infections will seem to be
effective in the short term. In the long term it will only increase the proliferation of
the virus as fever has a microstatic effect as cytokines work the best at these
higher temperatures.

9
Homotoxicological definition of illness

• Diseases are the expression of biologically purposeful defense


mechanisms against endogenous and exogenous homotoxins,
or the expression of the organism’s effort to compensate for
toxic damage it has sustained.

© IAH 2007 10

Biologically: “Bios” means “life”, “logos” means “word”, “study" or even “rule".
"Biological" means "in accordance to the rules of life". Every therapeutic action
that goes in against this biological fact, goes in against the basics of life. If we
suppress an inflammation and this inflammation process was meant to eliminate
homotoxines and their negative influences on the tissues, we stop a cleansing
process and remain with the intoxication effects. By blocking the cleansing effect
of an inflammation process we take a measure against life as the homotoxins
remain and will on long term intoxicate more in depth, what means the effects of
the homotoxins will be more seen into the cell instead of in the extra cellular
matrix.

10
Homotoxicological definition of illness

• Diseases are the expression of biologically purposeful defense


mechanisms against endogenous and exogenous homotoxins,
or the expression of the organism’s effort to compensate for
toxic damage it has sustained.

© IAH 2007 11

Purposeful : This term is extremely important in the homotoxicological definition


of disease. It means that the reaction of the defense system will be in proportion
to the needs to reach the target. This encompasses every regulation aspect
homotoxicology is referring to. Mobilization of defense will be at the level that is
needed to reach the target which in most cases is the elimination of the
homotoxin and his negative interactive activity with the cell and his environment
and to restore homeostasis. The regulation of the level of activity is done over a
complex mechanism of autoregulating systems, interacting one another and this
over many different mediators and feedback systems.

Most reactions of the defense system are purposeful, but inappropriate reactions
(unpurposeful) can occur and create diseases on their own. Auto-immune
diseases for example are an inappropriate reaction of the defense system. The
immune system is attacking body own tissues which under normal conditions
would be tolerated instead of attacked. The same is true for allergic reactions
such as hay fever. The reaction of the defense system is not in relationship to the
danger of the aggressor (the dust or the pollen) and therefore not purposeful.

11
Homotoxicological definition of illness

• Diseases are the expression of biologically purposeful defense


mechanisms against endogenous and exogenous homotoxins,
or the expression of the organism’s effort to compensate for
toxic damage it has sustained.

© IAH 2007 12

The defense mechanism is there to protect the organism from toxic burden. It is
not only functional when antigen is intruding into the system. The defense
mechanism should be a standby system at all times. In case of disruption of
homeostasis it can thus mount the appropriate response; be it immunological,
hormonal or enzymatic, etc… Only by being standby and alert all of the time an
effective and purposeful defense is possible. Failure of the system will result in
intoxication.
Regulation mechanisms are tightly controllers via positive and negative feedback
systems. Blocking or bypassing these feedback systems prevent regulation and
will lead to chronic diseases.

12
Homotoxicological definition of illness

• Diseases are the expression of biologically purposeful defense


mechanisms against endogenous and exogenous homotoxins,
or the expression of the organism’s effort to compensate for
toxic damage it has sustained.

© IAH 2007 13

We define a homotoxin as ANY substance that is toxic for the human organism (homo=man,
toxic=poison). The toxicity can be a direct biochemical molecular effect, a physical blocking effect
or even a disturbing interactive effect. So not only the homotoxin itself is of interest for us but also,
and maybe even more, the effects it creates (even on distance) on the cell.

We differentiate between endogenous and exogenous homotoxins.

Exogenous homotoxins are substances that are by definition already toxic for the human
organism in certain conditions (see preceding slide). Some of them are very well known by the
leman (tobacco, alcohol, drugs in many ways) others are lesser known (aromatics, colorants,
sweeters in food) or not known at all by (cadmium, evaporation of glues, gasses, radiations,…).
Endogenous homotoxins are created in the body itself. Mostly they are intermediate or waste
products of metabolic processes (e.g. CO2). Other endogenous homotoxins are the result of an
imbalance of hormonal secretion (e.g. oestrogen/progesterone), an inhibited or absent mediator or
intermediate substance secretion (e.g. insulin in diabetes, serotonin in depression) or to fast
reuptake (e.g. of to low levels of serotonin in depression) or just in contrary a to increased
repeated stimulation by exaggerated mediator supply (e.g. thyroid hormone in hyperthyroid
dysfunction).
Essential is the interfering or blocking activity of the homotoxin on normal functioning of the organ
systems or interactive steering or regulating systems (hormonal system, nervous system,…)
For more detailed information on homotoxins see the lecture ‘IAH AC Drainage and Detoxification’

13
© IAH 2007 14

The Disease Evolution Table (Formerly called the six-phase-table) is an


instrument to evaluate the evolution of the patient’s disease. A proper use of it in
practice gives not only an idea of the severity of the patient's disease, but will
also help the practitioner in setting up an effective therapy plan.

The table on the picture was the first original Disease Evolution Table or six
phase table of Reckeweg, translated from German into English (German version
1957).

14
© IAH 2007 15

On the horizontal axis we see six phases on this initial version. The inflammation
phase (current name) was called ‘reaction phase’ because of the body reacting to
the homotoxin. The current dedifferentiation phase (inverse of embryological
differentiation of cells) was called ‘neoplasma phase’ because of the new building
of tissue in tumors.

Interesting is also the fact that there were 2 blocs of 3 phases each, divided by a
biological division. On the left side of this division all the diseases occur where
the causal homotoxins or their effect are extracellular. On the right side of it the
presence or effect of the homotoxin is mainly intracellular.
The reference to the extra cellular matrix, or even Living Matrix, as we know it
now in modern histology today, was not existing at the time this table (1957) was
created as this concept was not known yet (Ground Regulation System,
Pischinger, 1975). Although Reckeweg referred to it by including the
mesenchymal level as a separate level (mesenchym should be under the
mesodermal layer) the matrix only became important in a new six phase table
early 90ties. Today we know that the Living Matrix has three levels which interact
with each other: the extra cellular matrix, the intra cellular matrix and the intra
nuclear matrix. We will discuss this later on in this lecture and even more in detail
in the lecture ‘IAH AC Living Matrix, Histology and Physiology’

As Dr. Reckeweg was strongly interested in toxicology only few references are
taken up on mind related diseases. Also this is completely different in the latest
version of the table.

15
© IAH 2007 16

On the vertical axis we recognize the 3 embryological layers: the ectoderm,


entoderm and mesoderm. As mentioned in the former slide the mesenchym
refers to the prestage of what is called later on the extra cellular matrix. From a
pure embryological point of view it should be classified under the mesoderm and
not occur as a separated tissue differentiation.

Important is the order in which the phases and the embryonic layers (and
resulting tissues) are classified. Reckeweg clearly was inspired there by Hering
as both are referring to Hering’s law in homeopathy. Hering’s law states that
diseases will evolve in time from the outside to the inside, from lesser important
organs and tissues to more important ones, from non cellular to cellular diseases.

16
Second table of homotoxicoses

Health Diseases

Humoral Matrix Cellular


phases phases phases

Tissues Excretion Inflamma- Deposition B Impregna- Degene- Dedifferen-


tion I tion ration tiation
O
L
O
Ectoderm G
I
C
Entoderm A
L

Mesenchym D
I
V
Mesoderm I
S
Intercellular I
O
Intracellular
N

© IAH 2007 17

In the end of the 80’s fundamental changes where done to the existing table. To
understand them we have to remind on certain histological aspects that where
discovered and implemented in that time. The main feature was that the matrix
phases were added to the existing concept of Reckeweg.

17
The terrain of the patient

• «La bactérie n’est rien, c’est le terrain qui fait tout.»

• “Bacteria are nothing,


the terrain is everything”

Claude Bernard
19th century

© IAH 2007 18

In the 19th century the French histologist Claude Bernard developed the
terminology ‘internal terrain’ or internal environment. He was referring to the
direct environment of the cell, structural an physiological. The life quality of the
cell is directly related to the purity of his direct environment as that is the area
where it takes his nutrition and energy from and deposits his waste products in.
Even Louis Pasteur, the discoverer of micro-organisms in modern medicine,
referred to Claude Bernard mentioning that a bacterial infection is more related to
a changed internal terrain of the patient rather than to the presence of a the
bacteria or other micro-organism.
The bacteria is not the cause of a bacterial infection, but the internal terrain of the
patient which became a culture medium that benefited the proliferation of the
micro organism. That is why antibiotics, from his point of view, are not a causal
treatment for all the patients (individual terrain) in the same way. In a very good
terrain an antibiotic can be a pure symptomatologic treatment due to the fact that
it was not necessary to give one.
Antibiotics are directly inhibiting the bacteria’s proliferation. Causal treatment
would be to cleanse the terrain in such a way that it becomes a poor breeding
ground for the bacteria and his proliferation is inhibited by deprivation. That
benefits the defense system that in the same time delay has to eliminate less
aggressors and above all: a clean and accurate terrain will give lesser chance for
recurrence.

18
Virchow

The Pischinger System

Pischinger

© IAH 2007 19

The internal terrain of Claude Bernard is a histological fact. In modern histology it


is called today the Living Matrix (LM), composed out of different levels or
components (extra-, intra cellular and intra nuclear). The extra cellular matrix is a
transmission area between all the regulative systems and the cell. Nerves,
capillaries, lymph vessels,… they all end or start in the ECM. None of them ends
or originates in the cell. Interactions between the different systems (nerve
system, blood stream, defense system, basic structure,…) take place over the
exchanges of highly differentiated mediators that will steer over the extra cellular
matrix (ECM). In this way the cell is directly related to the extra cellular matrix
and the quality of function and facilities is depending on the purity of the ECM
matrix and its transmission qualities.

For detailed information on this please consult the lecture ‘IAH AC Living Matrix
Histology and Physiology’.

19
© IAH 2007 20

The extra cellular matrix itself is built out of a fine meshed three dimensional web
of proteoglycans and glycosaminaglycans (mucopolysaccharides). A
proteoglycan is built out of a hyaluronic acid molecule, on which, connected
through binding proteins, the core protein is fixed. Horizontally, in tree-like
structure, transverse proteins are fixed that carry sugar complexes
(glycosaminoglycans, e.g., chondroitin sulphate).

For more detailed information on the matrix structure see also here the lecture
‘IAH AC Living Matrix Histology and Physiology)

20
Second table of homotoxicoses

Health Diseases

Humoral Matrix Cellular


phases phases phases

Tissues Excretion Inflamma- Deposition B Impregna- Degene- Dedifferen-


tion I tion ration tiation
O
L
O
Ectoderm G
I
C
Entoderm A
L

Mesenchym D
I
V
Mesoderm I
S
Intercellular I
O
Intracellular
N

© IAH 2007 21

The main reason why in the 1980’s the matrix was incorporated into the six
phase table was because of the fact that in that time homotoxicologists thought
that deposition of homotoxins was thought to take place in the matrix. Of course
today we query this fact.
In this version of the table t as well he embryological classification of the tissues
remained (as in Dr. Reckeweg’s table) but the phases where classified in 3
blocks of 2 phases. From an initial division of the table in two blocks (humoral
and cellular phases) the table was divided into 3 blocks, integrating the matrix as
a histological fact (humoral, matrix and cellular phases)

To be more correct in the nomination of the phases the ‘Reaction phase’ became
‘Inflammation’ phase as the reaction of the defense system is an inflammation in
the second phase. The ‘Neoplasma phase’ became ‘Dedifferentiation phase’ due
to the characteristic of the omnipotent facilities of the dedifferentiating cell (the
opposite of the embryological differentiating cell).

21
Six phases of homotoxicoses

• Excretion: expulsion of toxic products


• Inflammation: initiated cleaning by activating defense system
• Deposition: storage of toxic products in the extra-cellular space
• Impregnation: the main effect of intoxication becomes intra
cellular. Affection of enzyme systems starts
• Degeneration: intoxication destroys the cell
• Dedifferentiation phases: the cell dedifferentiates into an
undedifferentiated cell, neoplasma’s are created

© IAH 2007 22

Here we see the main characteristics of the six phases on the table. We will go
more in detail on the characteristics of each phase later on.

22
The biological division marks the
difference between extra-cellular and
intra-cellular intoxication.

From an organic point of view the


biological division is often the point
of no return.

© IAH 2007

The biological division is the imaginary line that divides the deposition and
impregnation phases in the former Dr. Reckeweg’s six-phase table. This means
that it runs down the centre of the six-phase table and through the middle of the
matrix phases. It is not simply a dividing line. It is symbolic and its strategic
therapeutic value is enormous.
Every intoxicating effect that crosses the biological division incurs often
irreparable damage to the cell. Or the homotoxin itself, or his effect will endanger
the cell’s health as destructive impact at cell nucleus and intercellular structures
will occur.
This is why the biological division is the dividing line between diseases with a
good prognosis and diseases with a dubious prognosis, between relative
intracellular purity and intact condition and an intracellular intoxication or
deficiency status, between reparable inhibition of function and irreparable
damage. In general terms, it can also be said to form the dividing line between
largely acute and largely chronic pathologies.
When the biological division is crossed, therapy will have to be more in depth.
After all, the phases to the left of the division can show full recovery if the body’s
own defense mechanism is properly stimulated and adequate drainage and
detoxification is achieved. Not only will the clinical symptoms disappear but the
terrain of the patient will give lesser chance to new aggressions and intoxications.
On the right side of the division the cell is involved, even damaged. This is where
the 3 pillars of homotoxicology will have to be integrated into the therapy strategy.
These 3 pillars are: 1. drainage and detoxification, 2. immunomodulation and 3.
cellular activation and organ regulation.

23
The biological division marks the
difference between extra-cellular and
intra-cellular intoxication or its
effect, between self regulation and
compensation.

From an organic point of view the


biological division is the point of
no return.

© IAH 2007

To the right of the biological division, treatment will have to be focused on stopping the
intracellular dysfunction due to intoxicating processes created by intra cellular presence of
homotoxins or extracellular presence of homotoxins with an intracellular destabilizing effect (e.g.
by stimulating cell respiration, using catalysts from the citric acid cycle or giving organ support by
the onset of composita preparations), ‘purifying’ the interstitial space (drainage) and compensating
for the permanent cellular damage resulting from the advanced intracellular intoxication (as far as
possible). Beside that often immunomodulating therapeutic measures must be taken (e.g.
inflammation regulating drugs) and drainage and detoxification measures (conform the 3 pillars of
homotoxicology). At the end we will try to bring the organism back to self regulation again.
The phases that touch the biological division on the left and right of the table are both
characterized by latent periods of freedom of symptoms, and this allows an organism to evolve
unobtrusively across the division. This is why treatment of the deposition phases and
impregnation phases is most difficult for the biotherapist as the symptoms not always express the
severity of the disease.
The opportunities for therapeutic evaluation in these middle phases are often vague, masked by a
lack of symptoms. In addition, the patient will also have to be treated even when he/she is
showing no clinical symptoms at all, something that some people consider to be completely
unnecessary. After all, there is no need to treat someone who does not feel ill !
In addition to activating the defense mechanisms at the level of the extracellular space, drainage
is also a crucial factor. Sometimes inflammation processes may even be encouraged in order to
achieve fast ‘purification’ of the intoxicated tissues. This inflammation may also appear
spontaneously as a facet of the healing process. We call this a forced or spontaneous ‘health
evolution’ or symptom displacement in the good sense.

24
H U M O R A L P H A S E S M A T R I X P H A S E S C E L L U L A R P H A S E S
Organ system Excretion Phases Inflammation Phases Deposition Phases Impregnation Phases Degeneration Phases Dedifferentiation Phases

Skin Episodes of sweating Acne Naevi Allergy Scleroderma Melanoma

Nervous system Difficulty concentrating Meningitis Cerebrosclerosis Migraine Alzheimer’s disease Gliosarcoma

Sensory System Tears, otorrhea Conjunctivitis, otitis Chalazion, cholesteatoma Iridocyclitis, tinnitus Macular degeneration, Amaurosis, malignant

N
media anosmia tumor

O
Locomotor Joint pains Epicondylitis Exostosis Chronic rheumatoid Spondylosis Sarcoma, chondroma
System arthritis

I
Respiratory Cough, expectoration Bronchitis, acute Silicosis, smoker’s lung Chronic (obstructive) Bronchiectasia, Bronchial carcinoma

S
Tract bronchitis emphysema

V I
Cardiovascular Functional heart Endocarditis, Coronary heart disease Heart failure Myocardial infarction Endothelioma
System complaint pericarditis, myocarditis

D I
Gastrointestinal Heartburn Gastroenteritis, gastritis Hyperplastic gastritis Chronic gastritis, Atrophic gastritis, liver Stomach cancer, colon
System malabsorption cirrhosis cancer

Urogenital Polyuria Urinary tract infection Bladder stones, kidney Chronic urinary tract Renal atrophy Cancer
System stones infection

C A L
Blood Reticulocytosis Leucocytosis, Polycythaemia, Aggregation disturbance Anemia, Leukemia
suppuration thrombocytosis thrombocytopenia

Lymph System Lymphedema Lymphangitis, tonsillitis, Lymph-node swelling Insufficiency of the Fibrosis Lymphoma, Hodgkin-/ non-
lymphadenitis lymph system Hodgkin-lymphoma

I
Metabolism Electrolyte shift Lipid metabolism Gout, obesity Metabolic syndrome Diabetes mellitus Slow reactions
disturbance

© 2000 by Biologische Heilmittel Heel GmbH


Hormone Globus sensation Thyroiditis Goitre, adenoma Hyperthyroidism, Menopausal symptoms Thyroid cancer

O
System glucose intolerance

L
Immune System Susceptibility to infection Weak immune system, Weak reactions Autoimmune disease, AIDS Slow reactions
acute infection immunodeficiency,

O
chronic infections

B I
Alteration* Reaction* Fixation* Chronic Forms* Deficits* Decoupling*

Psyche Functional psychological Reactive depressive Psychosomatic Endogenous Schizophrenic defective Mania, catatonia
disturbance, syndromes, manifestation, neuroses, depression, psychosis, states, mental
“nervousness“ hyperkinetic syndrome phobias, neurotic anxiety neurosis, deficiency
depression organic
psychosyndrome
*Phase nomenclature in
psychology.

© IAH 2007 25

The body deals with homotoxins in 6 different ways. Dr. H.-H. Reckeweg
classified the homotoxicosis (diseases) in this dynamic framework, i.e. the six-
phase table of homotoxicosis as he called it. In time a disease can evolve from
the excretion through the inflammation (formerly the reaction phases) to the
deposition phases. Subsequently there is an evolution from the impregnation
through the degeneration to the dedifferentiation phases (formerly the neoplasm
phases). The body may skip certain phases, i.e. evolution can take place without
symptoms from these phases appearing.
The six-phase table system not only allows us to understand the severity of a
disease (level of intoxication and the body’s reaction to this intoxication), but also
to make therapeutic forecasts (prognosis).
The six-phase table gives the practitioner a clear classification of diseases and
allows him to interpret any shift of symptoms correctly. In addition to its value as
an evaluation or assessment tool for the therapist, it is also of fundamental
importance for determining the actual antihomotoxic preparations (most products
are directly related to a certain status of the organism) in order to stimulate
favourable evolution in the shortest possible time.
The six phases in question are assigned to three groups of two (the humoral, the
matrix and the cellular phases), which are divided halfway through the matrix
phases by the biological division. Once this division is crossed, this indicates that
the homotoxins or their effects are evolving from extracellular to intracellular ; in
other words the homotoxins that were initially outside the cell can evolve into the
cell or the homotoxin is physically outside the cell but the intoxicating effect
occurs mainly in the cell.

25
H U M O R A L P H A S E S M A T R I X P H A S E S C E L L U L A R P H A S E S
Organ system Excretion Phases Inflammation Phases Deposition Phases Impregnation Phases Degeneration Phases Dedifferentiation Phases

Skin Episodes of sweating Acne Naevi Allergy Scleroderma Melanoma

Nervous system Difficulty concentrating Meningitis Cerebrosclerosis Migraine Alzheimer’s disease Gliosarcoma

Sensory System Tears, otorrhea Conjunctivitis, otitis Chalazion, cholesteatoma Iridocyclitis, tinnitus Macular degeneration, Amaurosis, malignant

N
media anosmia tumor

O
Locomotor Joint pains Epicondylitis Exostosis Chronic rheumatoid Spondylosis Sarcoma, chondroma
System arthritis

I
Respiratory Cough, expectoration Bronchitis, acute Silicosis, smoker’s lung Chronic (obstructive) Bronchiectasia, Bronchial carcinoma

S
Tract bronchitis emphysema

V I
Cardiovascular Functional heart Endocarditis, Coronary heart disease Heart failure Myocardial infarction Endothelioma
System complaint pericarditis, myocarditis

D I
Gastrointestinal Heartburn Gastroenteritis, gastritis Hyperplastic gastritis Chronic gastritis, Atrophic gastritis, liver Stomach cancer, colon
System malabsorption cirrhosis cancer

Urogenital Polyuria Urinary tract infection Bladder stones, kidney Chronic urinary tract Renal atrophy Cancer
System stones infection

C A L
Blood Reticulocytosis Leucocytosis, Polycythaemia, Aggregation disturbance Anemia, Leukemia
suppuration thrombocytosis thrombocytopenia

Lymph System Lymphedema Lymphangitis, tonsillitis, Lymph-node swelling Insufficiency of the Fibrosis Lymphoma, Hodgkin-/ non-
lymphadenitis lymph system Hodgkin-lymphoma

I
Metabolism Electrolyte shift Lipid metabolism Gout, obesity Metabolic syndrome Diabetes mellitus Slow reactions
disturbance

© 2000 by Biologische Heilmittel Heel GmbH


Hormone Globus sensation Thyroiditis Goitre, adenoma Hyperthyroidism, Menopausal symptoms Thyroid cancer

O
System glucose intolerance

L
Immune System Susceptibility to infection Weak immune system, Weak reactions Autoimmune disease, AIDS Slow reactions
acute infection immunodeficiency,

O
chronic infections

B I
Alteration* Reaction* Fixation* Chronic Forms* Deficits* Decoupling*

Psyche Functional psychological Reactive depressive Psychosomatic Endogenous Schizophrenic defective Mania, catatonia
disturbance, syndromes, manifestation, neuroses, depression, psychosis, states, mental
“nervousness“ hyperkinetic syndrome phobias, neurotic anxiety neurosis, deficiency
depression organic
psychosyndrome
*Phase nomenclature in
psychology.

© IAH 2007 26

The humoral phases are the excretion and the inflammation phases. They are
characterised by repeated attempts by the body to achieve spontaneous
detoxification (elimination). The intracellular structures always remain intact,
although we will see that numerous cells may be lost in the inflammation process
but will be replaced by intact, healthy cells afterwards. There is a spontaneous
trend towards improvement. This means that if further intoxication is prevented
and the patient is brought to a situation where elimination is promoted (e.g.
rest !), the disease will disappear, provided there are no mechanical obstacles
(e.g. blocked sinus in sinusitis). The prognosis for diseases in the humoral
phases is generally favourable and the recuperation process can be sped up
significantly by treatment with antihomotoxic preparations, with only a negligible
risk of side effects.

26
H U M O R A L P H A S E S M A T R I X P H A S E S C E L L U L A R P H A S E S
Organ system Excretion Phases Inflammation Phases Deposition Phases Impregnation Phases Degeneration Phases Dedifferentiation Phases

Skin Episodes of sweating Acne Naevi Allergy Scleroderma Melanoma

Nervous system Difficulty concentrating Meningitis Cerebrosclerosis Migraine Alzheimer’s disease Gliosarcoma

Sensory System Tears, otorrhea Conjunctivitis, otitis Chalazion, cholesteatoma Iridocyclitis, tinnitus Macular degeneration, Amaurosis, malignant

N
media anosmia tumor

O
Locomotor Joint pains Epicondylitis Exostosis Chronic rheumatoid Spondylosis Sarcoma, chondroma
System arthritis

I
Respiratory Cough, expectoration Bronchitis, acute Silicosis, smoker’s lung Chronic (obstructive) Bronchiectasia, Bronchial carcinoma

S
Tract bronchitis emphysema

V I
Cardiovascular Functional heart Endocarditis, Coronary heart disease Heart failure Myocardial infarction Endothelioma
System complaint pericarditis, myocarditis

D I
Gastrointestinal Heartburn Gastroenteritis, gastritis Hyperplastic gastritis Chronic gastritis, Atrophic gastritis, liver Stomach cancer, colon
System malabsorption cirrhosis cancer

Urogenital Polyuria Urinary tract infection Bladder stones, kidney Chronic urinary tract Renal atrophy Cancer
System stones infection

C A L
Blood Reticulocytosis Leucocytosis, Polycythaemia, Aggregation disturbance Anemia, Leukemia
suppuration thrombocytosis thrombocytopenia

Lymph System Lymphedema Lymphangitis, tonsillitis, Lymph-node swelling Insufficiency of the Fibrosis Lymphoma, Hodgkin-/ non-
lymphadenitis lymph system Hodgkin-lymphoma

I
Metabolism Electrolyte shift Lipid metabolism Gout, obesity Metabolic syndrome Diabetes mellitus Slow reactions
disturbance

© 2000 by Biologische Heilmittel Heel GmbH


Hormone Globus sensation Thyroiditis Goitre, adenoma Hyperthyroidism, Menopausal symptoms Thyroid cancer

O
System glucose intolerance

L
Immune System Susceptibility to infection Weak immune system, Weak reactions Autoimmune disease, AIDS Slow reactions
acute infection immunodeficiency,

O
chronic infections

B I
Alteration* Reaction* Fixation* Chronic Forms* Deficits* Decoupling*

Psyche Functional psychological Reactive depressive Psychosomatic Endogenous Schizophrenic defective Mania, catatonia
disturbance, syndromes, manifestation, neuroses, depression, psychosis, states, mental
“nervousness“ hyperkinetic syndrome phobias, neurotic anxiety neurosis, deficiency
depression organic
psychosyndrome
*Phase nomenclature in
psychology.

© IAH 2007 27

The matrix phases are the deposition and impregnation phases. The diseases in these phases
occur at the basic substance level, the basic bio regulation system (BBRS) or the so-called
Pischinger space or Ground Regulation System according to Pischinger. All those terms are
synonims.
The matrix phases are crucial in patient’s history as since it is in these phases that the actual step
from extracellular to intracellular homotoxin presence or effect occurs. The importance of a
properly functioning, i.e. not intoxicated, basic bioregulation system is fundamental to the
protection of the body against chronic degenerative diseases.
The cellular phases are the degeneration and neoplasm phases or dedifferentiation phases. They
are on the other side of the biological division. This means that intoxication has taken place not
only between the cells but also inside the cells or that extracellular intoxication has intracellular
effects. Slowly but surely the cell’s functions are inhibited up to the point of destruction. Self
regulation mechanisms fail and the body tries to compensate. Cell clearance over apoptosis
and/or the activity of the large granular lymphocytes (LGL’s) : natural Killer cells (NK-cells) and
cytotoxic cells (cT-cells) is unsatisfactory.
Condensation or the deposition of homotoxins in the cell is the main principle of the cellular
phases. As mentioned before it can be the presence of an intracellular homotoxin or the presence
of an extracellular one having an intracellular effect. Already the disturbance of a normal passage
of mediators to the cell might cause intracellular dysfunction. So, nevertheless intoxication of the
cell environment and disabled cell oxygenation can also cause cell death or dysfunction. The
intracellular structures can be irretrievably damaged. There is a spontaneous tendency towards a
worsening of the symptoms (if we give no treatment the patient’s condition will deteriorate -for
example, an arthrosis patient who has stopped moving and receives no therapeutic support) and
the prognosis is generally bad. Even in the case of complete drainage (insofar as this is possible)
of the homotoxins, the patient remains latently sick. The intracellular damage continues to exist,
even though a patient may no longer show clinical symptoms.

27
H U M O R A L P H A S E S M A T R I X P H A S E S C E L L U L A R P H A S E S
Organ system Excretion Phases Inflammation Phases Deposition Phases Impregnation Phases Degeneration Phases Dedifferentiation Phases

Skin Episodes of sweating Acne Naevi Allergy Scleroderma Melanoma

Nervous system Difficulty concentrating Meningitis Cerebrosclerosis Migraine Alzheimer’s disease Gliosarcoma

Sensory System Tears, otorrhea Conjunctivitis, otitis Chalazion, cholesteatoma Iridocyclitis, tinnitus Macular degeneration, Amaurosis, malignant

N
media anosmia tumor

O
Locomotor Joint pains Epicondylitis Exostosis Chronic rheumatoid Spondylosis Sarcoma, chondroma
System arthritis

I
Respiratory Cough, expectoration Bronchitis, acute Silicosis, smoker’s lung Chronic (obstructive) Bronchiectasia, Bronchial carcinoma

S
Tract bronchitis emphysema

I
Cardiovascular Functional heart Endocarditis, Coronary heart disease Heart failure Myocardial infarction Endothelioma

V
System complaint pericarditis, myocarditis

D I
Gastrointestinal Heartburn Gastroenteritis, gastritis Hyperplastic gastritis Chronic gastritis, Atrophic gastritis, liver Stomach cancer, colon
System malabsorption cirrhosis cancer

Urogenital Polyuria Urinary tract infection Bladder stones, kidney Chronic urinary tract Renal atrophy Cancer
System stones infection

C A L
Blood Reticulocytosis Leucocytosis, Polycythaemia, Aggregation disturbance Anemia, Leukemia
suppuration thrombocytosis thrombocytopenia
Lymph System Lymphedema Lymphangitis, tonsillitis, Lymph-node swelling Insufficiency of the Fibrosis Lymphoma, Hodgkin-/ non-
lymphadenitis lymph system Hodgkin-lymphoma

I
Metabolism Electrolyte shift Lipid metabolism Gout, obesity Metabolic syndrome Diabetes mellitus Slow reactions
disturbance

G
Hormone Globus sensation Thyroiditis Goitre, adenoma Hyperthyroidism, Menopausal symptoms Thyroid cancer

O
System glucose intolerance

L
Immune System Susceptibility to infection Weak immune system, Weak reactions Autoimmune disease, AIDS Slow reactions
acute infection immunodeficiency,

O
chronic infections

B I
Alteration* Reaction* Fixation* Chronic Forms* Deficits* Decoupling*

Psyche Functional psychological Reactive depressive Psychosomatic Endogenous Schizophrenic defective Mania, catatonia
disturbance, syndromes, manifestation, neuroses, depression, psychosis, states, mental
“nervousness“ hyperkinetic syndrome phobias, neurotic anxiety neurosis, deficiency
depression organic
psychosyndrome
*Phase nomenclature in
psychology.

© IAH 2007 28

From a homotoxicological point of view the patient’s symptoms can be fully


relieved but he/she often cannot be totally cured. Intracellular damage and cell
death is irreversible, cicatrisation after lesion will remain there for ever. Above
that every new significant intoxication in the affected area or organ will result in
the accelerated creation of a new progressing cellular phase. This means that the
chance is great that an arthrosis patient always remains an arthrosis patient at
cellular level even if he/she gets free of symptoms, a better mobility, etc... We
can ameliorate his state tremendously, at cellular level the witnesses of
degeneration will remain.
Leaving out the mental pathologies, this table provides a surprisingly simple
homotoxicological classification of diseases. The new table differentiates in terms
of the various organs and organ systems. It includes also the psychological
diseases, as was already done for the first time by the Italian internist and
homotoxicologist Dr. Ivo Bianchi.
The table provides several examples of homotoxicosis per ‘quadrant’. Classifying
all the thousands of diseases in this table, in this font, would probably result in a
six-phase table as big as a tennis court. The table is intended to be an aid to
reasoning, not an encyclopaedia. Diseases can be positioned correctly in the
table by analogy. The table contains no symptoms because it is possible for the
same symptom to appear in various diseases. For example, pain can be part of
an inflammation phase (e.g. in arthritis), a deposition phase (e.g. stone
formation), an impregnation phase (e.g. angina pectoris), a degeneration phase
(e.g. arthrosis) or a dedifferentiation phase (e.g. cancer of the bowel).

28
H U M O R A L P H A S E S M A T R I X P H A S E S C E L L U L A R P H A S E S
Organ system Excretion Phases Inflammation Phases Deposition Phases Impregnation Phases Degeneration Phases Dedifferentiation Phases

Skin Episodes of sweating Acne Naevi Allergy Scleroderma Melanoma

Nervous system Difficulty concentrating Meningitis Cerebrosclerosis Migraine Alzheimer’s disease Gliosarcoma

Sensory System Tears, otorrhea Conjunctivitis, otitis Chalazion, cholesteatoma Iridocyclitis, tinnitus Macular degeneration, Amaurosis, malignant

N
media anosmia tumor

O
Locomotor Joint pains Epicondylitis Exostosis Chronic rheumatoid Spondylosis Sarcoma, chondroma
System arthritis

I
Respiratory Cough, expectoration Bronchitis, acute Silicosis, smoker’s lung Chronic (obstructive) Bronchiectasia, Bronchial carcinoma

S
Tract bronchitis emphysema

I
Cardiovascular Functional heart Endocarditis, Coronary heart disease Heart failure Myocardial infarction Endothelioma

V
System complaint pericarditis, myocarditis

D I
Gastrointestinal Heartburn Gastroenteritis, gastritis Hyperplastic gastritis Chronic gastritis, Atrophic gastritis, liver Stomach cancer, colon
System malabsorption cirrhosis cancer

Urogenital Polyuria Urinary tract infection Bladder stones, kidney Chronic urinary tract Renal atrophy Cancer
System stones infection

C A L
Blood Reticulocytosis Leucocytosis, Polycythaemia, Aggregation disturbance Anemia, Leukemia
suppuration thrombocytosis thrombocytopenia
Lymph System Lymphedema Lymphangitis, tonsillitis, Lymph-node swelling Insufficiency of the Fibrosis Lymphoma, Hodgkin-/ non-
lymphadenitis lymph system Hodgkin-lymphoma

I
Metabolism Electrolyte shift Lipid metabolism Gout, obesity Metabolic syndrome Diabetes mellitus Slow reactions
disturbance

G
Hormone Globus sensation Thyroiditis Goitre, adenoma Hyperthyroidism, Menopausal symptoms Thyroid cancer

O
System glucose intolerance

L
Immune System Susceptibility to infection Weak immune system, Weak reactions Autoimmune disease, AIDS Slow reactions
acute infection immunodeficiency,

O
chronic infections

B I
Alteration* Reaction* Fixation* Chronic Forms* Deficits* Decoupling*

Psyche Functional psychological Reactive depressive Psychosomatic Endogenous Schizophrenic defective Mania, catatonia
disturbance, syndromes, manifestation, neuroses, depression, psychosis, states, mental
“nervousness“ hyperkinetic syndrome phobias, neurotic anxiety neurosis, deficiency
depression organic
psychosyndrome
*Phase nomenclature in
psychology.

© IAH 2007 29

By the description of the ground regulation system by Prof. Alfred Pischinger the
importance of the extra cellular space became apparent. That is why it was
integrated into the 6 phase table. As deposition of toxins and impregnation of
toxins or their effects from a distance on the cell both have to do with the location
of the homotoxins (present in the ECM) both phases were called matrix phases.

Dysregulation in the matrix has a direct effect on the intracellular and intranuclear
matrix. If repair mechanisms ans regulatory mechanisms cannot compensate any
more for the effect of the toxins in the matrix, diseases ensues on a cellular level.
This is why diseases which only affects the regulatory enzymes and cause
deposition in the extracellular matrix are called the deposition hases and
impregnation phases respectively.

In this way, 3 blocs of 2 phases each were created instead of the 2 blocs of 3
phases like it was in the original six phase table of Dr. Reckeweg.

For more information on the ECM study course IAH AC Matrix Histology and
Physiology.

29
Disease Evolution
Table
DET
Anno 2007

© IAH 2007 30

In the 1990’s version of the six phase table the different tissues where not named
in accordance to their embryological origin. The names of the tissue referred to
the nomenclature which is used in modern medicine. Due to this the importance
of the embryological origin of the tissue was lost. There was a strong need to
combine the precision of the embryological origin and the modern tissue
terminology as is used in daily practice. That is why anno 2006 homotoxicological
experts worked together to create this new six phase table, now called the
Disease Evolution Table or DET. A lot has changed compared to the former
tables. Also the examples of diseases occurring in the table are actualized.

The present table includes or classifies the tissues to their embryological origin
again, referring to their most plausible vicariations into the same embryological
layer. The principle of the six phases remains the same although a colouring is
added to symbolize from white to black the purity of an excreting organism and
the sombre prognosis of cell death and dedifferentiation. In contrary to Dr.
Reckeweg’s original table the mesenchym is classified under the mesoderm as
embryological it originates from there. That is no more than histological correct to
do so.

Accordingly the homeopathic approach of the patient and referring to the materia
medica, the ‘mind’ is at the top of the table and no longer at the bottom.

30
Ectodermal

© IAH 2007 31

First of all we see that the classification of humoral, matrix and cellular at the top
of the table has disappeared. The reason for that is to make very clear that in no
way this table wants to refer to the topographic position of the homotoxin in the
body but only to the place of his main effect and the reaction of the body to that
effect. As most phases fade into each other like also the living matrix levels are
fading into each other, every reference to a topographic position of the homotoxin
itself might lead to false conclusions as a disease might occur due to the effect of
a homotoxin far away from where the homotoxin itself is hosted.

The main tissues originating from the ectodermal layer are the skin, the upper
respiratory pathway, the nerve system, the eye and the autonome nerve system.
Diseases related to these tissues will be found in this part of the six phase table.

31
Endodermal

© IAH 2007 32

The endodermal tissues are the lower respiratory tract, the intestinal tract and the
urogenital tract (not the kidneys). Beside those tissues we also find here the
exocrine tissues (sexual, digestive and respiratory) and the endocrine system
with its glands. Diseases related to these tissues will be found in this part of the
six phase table.

32
Mesodermal

© IAH 2007 33

The biggest part of the table is taken up by the deeper tissues. As mentioned
before, and in contrast to Dr. Reckeweg’s classification, the mesenchym (old
name for connective tissue) belongs to the mesodermal layer. The tissues that
originate from the mesodermal layer are the connective tissue, the bone tissue,
the blood, the cardiovascular system, the lymph system, the joints (intra articular
structure), the kidneys, the serous tissue, the germinal tissues (both genders)
and the muscles.

Diseases related to these tissues will be found in this part of the six phase table.

33
Di
se
as
e ev
ol
ut
io
n

© IAH 2007 34

Dr. H.-H. Reckeweg was trained in traditional homeopathy. One of the


cornerstones of teaching in this form of medicine is Hering’s Law.
This states that a disease evolving to recovery of health will do this from the
inside out, from vital to less vital organs, from the torso to the extremities
(centrifugally). A disease that is suppressed or becomes chronic tends to move to
deeper lying (organ) tissues (centripetally).
Dr. Reckeweg incorporated this law, this idea, into his Homotoxicology, as
defined in his six-phase table. He called the displacement of symptoms
‘vicariation’. Nowadays the term vicariation is left due to his etymological origin.
The former terminology ‘progressive vicariation’ is called ‘disease evolution’ now.
Disease evolution says what it really is: a movement of the accents of intoxication
from the left to the right and from the top to the bottom of the table.

34
Di
se
as
e ev
ol
ut
io
n

© IAH 2007 35

Disease evolution
The progress of a disease in time, whereby the movement is from a left-hand phase to a right-
hand phase in the six-phase table, is called disease evolution. For the patient this means a
worsening of the situation, as the homotoxins are tending towards a deposition phase, possibly
from extracellular to intracellular, instead of being processed and eliminated. Again we want to put
an accent on the fact that not the topographic position of the homotoxin is crucial, but the effect it
has. In a disease evolution the effects of intoxication will move from the left to the right on the
table, and from the top to the bottom.
Disease evolution induces chronic conditions. Often a suppressive treatment is behind this
evolution. When an acute condition is treated suppressively, the homotoxins might condense or
bound into the extra cellular matrix. After some time the toxins might disturb interactive regulation
processes at the level of the ECM, intrude into the cell or disturb the cell function from outside and
interfere with cell to matrix and cell to cell communication, leading to cellular disease and even
genotoxicity which results in cancer.
If, for example, eczema is suppressed (e.g. by using a corticoid ointment locally), the homotoxins
that cause the eczema – the eczema is the biologically efficient defense against homotoxins
expressed at the level of the skin – will be moved by the body to an alternative elimination
channel. This may be over the BBRS, the blood circulation or the lymphatic system. If these
homotoxins are deposited in the bronchial cells with the intention of eliminating them via the
respiratory tract, they will affect the respiratory system and can, for example cause bronchial
asthma.
Disease evolution can last for decades. This means that years of apparent health can lie between
two phases of disease. This is because the deposition phases nearly always pass unnoticed.
Many apparently innocent illnesses such as flu, viral childhood diseases, herpes labialis, etc. are
more serious in homotoxicological terms than apparently severe, acute inflammatory diseases in
traditional medicine, such as arthritis, nephritis or purulent inflammation of the bladder. The first
group is, after all, viral and so immediately crosses the cellular wall, causing intracellular
intoxication that involves a very real risk of irreparable cellular damage. The second group
includes all phases of inflammation, which may be accompanied by pain and appear more serious
but in which the intoxication is between the cells. The intracellular structures are in no danger of
damage unless there are complications.

35
Di
se
as
e ev
ol
ut
io
n

© IAH 2007 36

The above comparison clearly shows the need to take a different attitude if the
result is to be a correct homotoxicological evaluation of the severity of the
disease. We must not concentrate simply on the subjective complaints of the
patient, but must also determine his/her position in the disease evolution table
and, even more importantly, the extent to which this disease is likely to move to
the right or the left in this table.
Suppression of biologically purposeful body defense mechanisms, such as fever
in case of viral infections, is only acceptable if the situation really seems to be
getting out of hand. Suppression should never be the response to the first
symptoms. This type of therapeutic approach is under no circumstances
recommended for prevention. The possible bacterial complication of a viral
rhinitis rarely merits a broad-spectrum antibiotic. Nevertheless many general
practitioners prescribe these as a matter of course. Homotoxicologically
speaking, this is a catastrophe !
If we reserve symptom suppression treatments (antibiotics, corticosteroids, fever
reducing preparations, etc.) for life threatening situations, they will work very well
in those moments. If we have already used them extensively on a patient, they
will be found to have lost their efficacy when a serious pathology arises and it will
be necessary to raise the (toxic) dose considerably.

36
He
alt
h
ev
ol
ut
io
n

© IAH 2007 37

Diseases that move from right to left on the disease evolution table are called health evolutions.
The former terminology was ‘regressive vicariation’. This terminology is removed due to the
etymological origin that doesn’t say anything about what essentially is going on in the body. Health
evolutions occur in a ‘recovering’ body and serve only one purpose: elimination.
The patient referred to above, with his bronchial asthma, who has no further attacks after a while
but who does develop eczema, is undergoing health evolution. The homotoxins are evolving from
deeper tissues to the surface. The homotoxicologist will try to treat the eczema biotherapeutically,
so that the defense mechanisms are encouraged locally in the ECM and the homotoxins are
rendered harmless and eliminated.
Health evolution is not always more pleasant for the patient than the existing condition. Arthritis is
more painful than arthrosis, eczema is visible, asthma is not always apparent, diarrhoea following
chronic constipation may be a blessing in homotoxicological terms, but hell for the patient.
It is therefore essential to provide the patient with adequate support, to motivate and to explain
why the reaction and elimination phases are so important. In any case, suppressive treatment of
the symptoms resulting from health evolution is absolutely contra-indicated for the reasons
already explained. We need to support the body’s mechanisms biotherapeutically and not try to
control them. The latter could possibly mean that we would be acting against the body’s own
purposeful defense mechanisms, something that is to be avoided at all costs.

37
How to classify diseases into the
Disease Evolution Table?

Decision tree

© IAH 2007

In this part of the lecture the characteristics of each phase are looked at in detail.
At the end a decision tree is presented by which, over simple questions, the right
phase of the present disease is selected.

As the antihomotoxic therapy depends on the phase the patient is in a right


classification of diseases by the student is mandatory.

38
• The disease evolution table is a
dynamic homotoxicologic
classification of diseases. The six
phases are referring to the way
the organism deals in the different
tissues with the presented
homotoxins.

© IAH 2007 39

The main character of the disease evolution table is that it takes in consideration
the dynamic aspect of a disease. The same homotoxin can by the evolution of
time create diseases in different phases. To evaluate our patient today we must
be able to look at the evolutions of disease done in the past (patient history) and
the evolutions of disease that might probably follow (prophylactic approach).

The reaction of the body on the presence of homotoxins determines the phase
the patient’s disease is in. So, not the homotoxin itself but the way the organism
deals with it is the main parameter

39
Excretion phases
• The organism is in a status of
hyperexcretion, without any
mobilization of defense.
• Beside an increased excretion
there is no clinical sign of disease

© IAH 2007 40

Excretion phases cover all the hypersecretions (endocrine) and hyperexcretions


the patient makes in his different organs and tissues. As those secretions and
excretions are increased in comparison to the normal standards in the population,
they should be seen as a first state of disease. Of course the presence of
homotoxins is a dormant danger and elimination and detoxification is needed but
in normal conditions detoxifying organs and excretion systems will eliminate them
without any clinical symptoms shown.

Although there is a charge of intoxication by the normal way of living, the body
deals with it without causing any manifestation of defense. Thus elimination of
toxins goes over a normal increased excretion process and the patient has no
other clinical complaints at all.

40
Inflammation phases
• Mobilization of defense
• The process of inflammation is a
cleanse of the ECM
• -itis

© IAH 2007 41

Once homotoxins get accumulated at the level of the ECM defense will be
mobilized to counter the intoxication status. A local manifestation of defense is
called ‘inflammation’, the reason why in acute inflammations the patient is in an
inflammation phase. All acute inflammations are classified in this phase.

Important is that we see this inflammation as a trial of the organism to get away
with the toxins. Phagocytosis may be seen as the first step of detoxification.

All characteristics of inflammation might be present: swelling, redness, pain,


temperature increase an loss of the affected tissue.

Inflammation should be seen as a ‘turbo-cleaning’ of the matrix. The cell is not


involved although inflammation processes can damage the cell (e.g. free radicals
released by frustrated neutrophiles).

41
Deposition phases
• Homotoxins are stored in the
ECM
• No severe clinical symptoms, few
complaints
• Severe risk of disturbance of the
cell function and intoxication in
the long term by storage nearby
the cell

© IAH 2007 42

If inflammation pathways are blocked or the amount of homotoxins gets out of


hand the organism will chose a process of (temporary) storage or deposition of
the homotoxins. In first resort this will be done at the level of the ECM. Literarily
homotoxins are bound into the three dimensional web of proteglycans. Thus a
quite dangerous situation appears as few clinical signs are seen in deposition
phases with very few complaints (in the beginning) from the patient but at the
same time the storage of this toxic burden will threaten the living cell and
endanger adequate functioning. It is only a question of time before the
homotoxins will impregnate into the cell or from outside the cell interfere in the
cell function where they can have many effects on cell functions

42
Impregnation phases
• The homotoxins impregnate into
the cell or remain extracellular
but have intracellular intoxicating
effects
• Illnesses appears often in
attacks with great periods of
latency
• Acute life threatening situations
possible

© IAH 2007 43

Once the homotoxins impregnate from the ECM into the cell or have intracellular
effects, diseases of the impregnation phases appear. Cell by cell gets more or
less intracellularly obstructed in his metabolic processes. We see appear less
adequate functioning of the cell and the reactions of the organism towards the
homotoxins is often not purposeful anymore. Often we see great periods of
latency whereas a minimal load of a specific homotoxin gives an overreacting of
the organism’s defense (asthma, hay fever, migraine, gastric ulcer,…)

Impregnation phases can be reached in a very short time span. It depends on the
characteristic of the homotoxins. Most viruses will try to get into a host cell to
proliferate. It happens fast and although the organism will try to develop a specific
defense (Ig) and eliminate the infected cells (T cell activity and NK cell induced
elimination) the acute situation is an impregnation phase due to the intra cellular
presence of the homotoxin. Even if afterwards there is a fully restoration of the
tissue and the lost cells are replaced, the viral condition remains an impregnation
phase for the time the virus is present as the virus gets incorporated into the
genetic material of the cell. In post viral syndromes this situation might even last
for a long time, even for years.

43
Degeneration phases
• The cell dies by intoxication
• Degenerative disorders
• -oses
• Loss of tissue and hardening of
tissue

© IAH 2007 44

The intra cellular intoxication by the homotoxins or their intracellular intoxication


effect is at that level that the cell dies. The progressing of the intoxication causes
function loss of the affected cell till it dies. In the long term we see tissue loss and
limited function of the whole affected tissue.

By definition degeneration phases accommodate chronic degenerative diseases,


most of them irreversible in time.

44
Dedifferentiation phases
• Uncontrolled cell growth
• Omnipotence of new cells (back
to origin before differentiation)
• Cancer, tumors
• Loss of tissue functions

© IAH 2007 45

The dedifferentiation phases accommodate all diseases in which cell proliferation


(tissue growth) is the main characteristic. Cells lose their specificity and
dedifferentiate to omnipotent cells (inversed embryological specificity) that can
easily migrate to other locations in the body (metastases). All malignant tumors,
cancers, are classified here.

45
© IAH 2007 46

In the following slides we will discuss a few question by which it becomes more
easy to classify a patient’s disease into the disease evolution table. The decision
tree is not always conclusive but in most cases it will be of a great help.

Starting from the clinical data the questions can be answered and the
classification in the right phase can be done. As we will see in other lectures the
classification of the patient’s disease in the table has consequences as well as for
the severity of his disease as for the therapy plan that needs to be made to treat
the current status.

46
Decision tree

Features Phase characteristics Therapy

© IAH 2007 47

We first will have to look at the features the patient is presenting, compare them
to the characteristics of the phases of the Disease Evolution Table and pull out of
this conclusions for the structure of our therapy. Not all the phases will be treated
in the same way and therefore this decision tree is made.

47
Yes:
Chromosomal damage, Malignancy present
Treatment
atypical cells, Pre-malignancy present
frank malignancy
PPG, MPG;
NO CPG, ORPG

Yes:
Tissue destruction Degeneration present Treatment

PPG, MPG;
CPG, ORPG
NO

Enzyme damage,
functional damage Yes:
Functional disturbance
Exacerbations with Treatment
on
periods of normality
a tissue level
PPG, MPG;
CPG, ORPG

© IAH 2007 48

In the decision tree we start from the worst case scenario to the best.

First we look from a pure conventional medical approach if there is malignancy or pre-malignancy
present. At the level of the cell this means that there is chromosomal damage, that there might be
atypical cells or pure frank malignancy. If this is the case we are in the dedifferentiation phase and
the treatment will be the full 3 pillars of homotoxicology which are 1. drainage and detoxification,
2. immunomodulation and 3. cell and organ support. These 3 pillars are filled in with medications
containing plant preparation groups (PPG), mineral preparation groups (MPG), catalysts
preparation groups (CPG) and organ preparation groups (ORPG).

If no malignancy is present we go down the tree to the next phase and look if degeneration is
present. Clinically we will find tissue destruction. If this is the case we are in the degeneration
phase and again the 3 pillar approach is necessary as beside the ECM treatment the defense
system needs to regain his regulation capabilities and cell support and organ support should
compensate for the cell damage.

If also no degeneration is present we will search for a functional disturbance on a tissue level. We
might discover enzyme damage, functional damage, exacerbations with periods of normality. If
this is the case the patient is in the impregnation phase and the 3 pillars of homotocicological
treatment should be involved in the therapy protocol.

48
Tissues aggregated in Yes:
abnormal benign growths Deposition present Treatment
or substances have
aggregated into
deposition PPG, MPG
NO

Yes:
Inflammatory process
Acute inflammation present Treatment
a once off process

PPG, MPG
NO

Increased secretion
of a normal physiological Yes:
Increased excretion
Process in view Treatment
of fluids,
of a homotoxin
neurotransmitters
PPG, MPG

© IAH 2007 49

If no enzyme damage or tissue damage is present we will look if deposition is


present. Clinically we might find tissues aggregated in abnormal benign growths
or substances that have aggregated into deposition. If this is the case the patient
is in deposition phase and needs to be treated with the 2 first pillars (drainage
and detoxification on one hand and immunomodulation on the other hand. No
organ preparation groups or catalysts preparation groups are used.

If there is no deposition we look after acute inflammation. Clinically we should


find a once off process of inflammation. If this is the case the patient is in the
inflammation phase. Also here the first two pillars of homotoxicological treatment
are needed.

If no inflammation is present but we see increased excretion of fluids,


neurotransmitters or other body own substances the patient deals with an
excretion phase. In this case mostly the first pillar of homotoxicological treatment
will do (drainage should be sufficient to support the patient). In some cases
immunomodulation might be interesting to speed up the process of cleanse and
to avoid reccurence.

49
Three Pillars of Homotoxicology:
Time Frames of Treatment

DETOXIFICATION IMMUNO- CELLULAR ACTIVATION


MODULATION AND ORGAN
REGULATION

© IAH 2007 50

Once right of the Regulation/Compensation Division on the Disease Evolution


Table we have to understand that a simple drainage, even in combination with an
immunomodulating therapy will not be sufficient due to the cellular character of
the disease. Right of the division the cell is intracellularly involved. To avoid
further damage to cell (and tissue, thus also organ) an additive cell and organ
support is needed.

In antihomotoxic medicine organ support is done by application of compositum


preparations. Cell support is mostly achieved by the application of catalysts
(isolated or incorporated into compositum preparations).

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Basic homotoxicologic questions (1)

• What is the clinical diagnosis today?


• Where would I put that diagnosis on the disease evolution table?
• What clinical data gives me the patient’s history?
• Is the current diagnosis probably related to one or more of the
historical data?

© IAH 2007 51

The questions on the next slides must help us to be able to set up a therapeutic
approach, starting from the patient’s history and his current position and former
evolutions on the disease evolution table.

The logical succession of the questions must lead to the proper choice of the
type of antihomotoxic medications that should figure in the final therapeutic
protocol.

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Basic homotoxicologic questions (2)

• If related, what type of disease or health evolution is going on in


this patient?
• What are the therapeutically consequences of this evolution?
• How will they be integrated in the protocol for the treatment of
the current disease?

© IAH 2007 52

52
Basic homotoxicologic questions (3)

• Which medications must be taken into consideration?


• Drainage medications
• Inflammation regulating drugs
• Cell support
• Organ function support
• Life quality
• Symptomatology
• How does the final protocol look like?

© IAH 2007 53

53
Backup library

© IAH 2007

54
Hans-Heinrich Reckeweg

• Born on 9 May 1905 in Herford


• 1924-1930 Studied medicine in Würzburg,
Berlin, Münster and then Berlin again
• 1930 Earned doctorate with a thesis on the
dietetic treatment of stomach ulcer
• 1930-1932 Junior doctor in Völklingen and
Harburg

© IAH 2007 55

Born in Herford, Westphalia, Germany, in 1905, Hans-Heinrich was the eldest of


a family of five children. He was very diverse in his interests. Hans-Heinrich had
musical (piano) interests that he kept as an adult and practiced to an expertise
that gave him many times the appreciation of his occasional audience. Later he
started painting in his freetime. His father, Heinrich-Friedrich Reckeweg was a
school teacher but became an homeopath at later age. He was very pleased his
eldest son choose for medicine that he studied at the universities of Würzburg,
Berlin, Münster to finalize in Berlin. During his medical studies already he was
very interested in toxicology and natural medicine. Especially the colleges of Prof.
August Bier brought him to the insight that gentle medicine was where he would
stand for. In these years he would go deeply into the study of homeopathy.

His first practice experiences as an MD where in the 2 years he was a junior


doctor in Völklingen and Harburg.

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Hans-Heinrich Reckeweg

• 1 May 1935 Started his first practice in


Berlin as a doctor with dispensing rights
• 1936 Founded Heel (Herba est ex luce)
• 26 own products: Heel’s Drops
• 1948-1949 Developed the theory of
homotoxins

© IAH 2007 56

After his 2 years as junior doctor he started his own practice in 1935. As usual in
that time he had also dispensing rights. As he was using his own homeopathic
formulas he needed a laboratory to have them at his disposition. That is why in
1936 he founded Heel. The name is an abbreviation of Herba Est Ex Luce which
means: the plant comes out of the light. Initially he created 26 products he called
‘Heel’s Tropfen’, which is German for ‘Heel’s drops’. Later the range became
much more extended to the variety of products we still know today.

In 1948 and 1949 the theory of homotoxins, leading to disease, took form.
Although there where already earlier articles and lectures about the basic
principles of homotoxicology, it took till 1955 before his basic work on
Homotoxicology, “Homotoxins and homotoxicoses – Principles of a synthesis in
medicine” came on the market.

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Hans-Heinrich Reckeweg

• 1945-1955 Practiced in Triberg


• 1952 Publication in the Münchener
Medizinische Wochenschrift
• “Homotoxins and the options for
treating homotoxicoses”
• 1955 “Homotoxins and homotoxicoses –
Principles of a synthesis in medicine”

© IAH 2007 57

Dr Reckeweg was a great lecturer and was able to convince many people out of
his audiences to follow the pathway of integrative gentle medicine he was
standing for. After years of practice, many lectures and articles, he finally
published his integrative approach in a book in 1955. Still today this basic work
inspires many students in gaining more in-depth knowledge on homotoxicology.

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Hans-Heinrich Reckeweg

• 1955 Moved to Baden-Baden


• 1961 Founded the International Society of
Homotoxicology
• 1962 “Homotoxin-Journal”
• Founded the International Society of
Biological Medicine
• 1972 Started the periodical “Biologische
Medizin” (Biological Medicine)

© IAH 2007 58

Once moved to Baden-Baden, Germany, the expansion of the Heel remedies


was a fact. Over there the facilities were growing fast.

In 1961 dr. Reckeweg founded the International Society of Homotoxicology to


group the homotoxicological practitioners, first only on German soil, later also
abroad. The Homotoxin journal was an instrument to inform the practitioners
about new insights into homotoxicology, successful protocols, congresses, etc…
In 1972 the Homotoxin journal disappeared and was replaced by the medical
journal ‘Biologische Medizin’ (Biological Medicine).

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Hans-Heinrich Reckeweg

• 1976 “Homotoxicology, comprehensive


vision of a synthesis in medicine”
• 1978 “Cancer problems”
• 1977 and 1981 “Homeopathia
Antihomotoxica”
• 1978 Sold the company Heel to Quandt
• 1978 Emigrated to the USA

© IAH 2007 59

In the years that followed Dr. Reckeweg was very productive in publishing books
on different homotoxicological themes. He even published a materia medica and
a repertory dedicated purely to the components he was using in his formulas.

In 1978 Dr. Reckeweg sold his company, that till than had been a family
company, to Delton with main shareholder Stefan Quandt. By these huge
investments into the Laboratoria Heel became possible and in the years that
followed Heel became available for the patient in more than 70 countries
worldwide.

Dr. Reckeweg and his family moved to the states where in Albuquerque, in the
state New Mexico, he founded a new company BHI (Biological Homeopathic
Industries) to conquer the USA with homotoxicology. He created a range of 52
new products, known as the BHI-products. Today also this company became a
full property and subsidiary of Ergo-Pharm, a pharmaceutical branch of the
financial holding ‘Delton’, property of Stefan Quandt. BHI is now renamed Heel
Inc.

59
Hans-Heinrich Reckeweg

• 1978 Founded BHI, developed 52 new


homeopathic drugs
• 13 June 1985 Died in Bircher-Benner
Hospital, Zürich

© IAH 2007 60

In the beginning of the 1980s Dr. Reckeweg suffered a stroke which he never
fully recovered from. He transferred ownership of his American company to his
daughter Monica Doerper-Reckeweg and his son in law Friedrich Doerper.

At 80 years of age Dr. Hans-Heinrich Reckeweg died in Zurich, Switzerland. In


the meanwhile the company he founded became the worldwide number 2 in
complementary medicine. Homotoxicology now is a concept in medicine that is
studied and followed by thousands of general practitioners and specialists all
over the world. Every second complex homeopathic medication used worldwide
is one of Heel.

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