X.

DRUG STUDY
Ceftriaxone
Generic Brand Classification Dosage Mechanism of Indication Contra- Adverse Nursing
Name Name Action indication Reaction Consideration
Ceftriaxone Keptrix Cephalosporins 850 mg Inhibits Treatment Hypersensitivity Rash Assessment:
bacterial cell for to Diarrhea 1. Assess patient
OD wall synthesis, susceptible Cephalosporins. G.I. sensitivity to
rendering cell infection. disturbances Cephalosporins
IV wall osmotically Treatment Nausea
Unstable, of LRTI. Planning:
leading to cell 1. Discuss all
death. aspect of the
drug therapy to
the primary
care giver.

Implementation:
1. Instruct the
primary care
giver to report
signs of
adverse
reaction.

Evaluation:

Absence of signs and

symptoms of infection.

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 Clindamycin
Generic Brand Classification Dosage Mechanism of Indication Contra- Adverse Nursing
Name Name Action indication Reaction Consideration
Clindamycin Dalacin Lincosamides 2 ml Inhibits Serious Hypersensitivity Gastro- Assessment:
bacterial cell anaerobic To Intestinal Assess for allergic
OD wall protein infection lincosamides disorder reaction.
synthesis by especially Nausea
Route: binding to the those Diarrhea Planning:
P.O. 50s subunits of caused by Give before meals..
ribosome Bacteroides
Fragilis
Implementation:
Advise the primary
care giver to report
any adverse reaction.

Evaluation:

Absence of signs and

symptoms of infection.

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 Amikacin

Generic Brand Classification Dosage Mechanism of Indication Contra- Adverse Nursing

Name Name Action indication Reaction Consideration
Amikacin Amikacide Aminoglycoside 125 mg Binds to Treatment of Hypersensitivity Oliguria Assessment:
s bacterial infection To amikacin. Hearing loss Assess for history of
OD ribosomal caused by allergic reaction to
subunit to susceptible medicines.
Route: cause strains of
I.V misreading of microorganism. Planning:
the genetic Discuss all aspect of
code which the drug therapy to
leads to the primary care
inaccurate giver.
peptide
sequence of
protein Implementation:
synthesis and Advise the primary
bacteria deat care giver to report
any adverse
reaction.

Evaluation:

Absence of signs
and symptoms of
infection.

Isoniazid

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Generic Brand Classification Dosage Mechanism Indication Contra- Adverse Nursing
Name Name of Action indication Reaction Consideration
Isoniazid Isonicotinic Anti- 1.8 ml Inhibits RNA Pulmonary and Should not be Fever Assessment:
tuberculosis synthesis, extrapulmonary given for G.I. Assess for history of
OD decreases Tuberculosis patient with disturbances allergic reaction to
tubercle bacilli drug induced Vomiting medicines.
Route: replication. liver disease.
P.O. Planning:
Give 30 minutes
before milk intake

Implementation:
Advise the primary
care giver to report
any adverse
reaction.

Evaluation:

Decreased
symptoms of
Tuberculosis.

Rifampin Forte
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Generic Brand Classification Dosage Mechanism Indication Contra- Adverse Nursing
Name Name of Action indication Reaction Consideration
Rifampin Rifampicin Anti- 1.8 ml Inhibits DNA- Maintenance Should not be G.I Assessment:
Forte tuberculosis dependent phase given for disturbances Assess
OD polymerase, treatment of patient with Nausea knowledge/teach
decreases pulmonary and drug induced vomiting patient possible side
Route: replication. extra- liver disease. effects and adverse
P.O. pulmonary symptoms to report.
tuberculosis.
Planning:
Give 30 minutes
before milk intake.

Implementation:
Advise the primary
care giver to report
any adverse
reaction.

Evaluation:

Decreased
symptoms of
Tuberculosis.

Pyrazinamide

Generic Brand Name Classification Dosage Mechanism of Indication Contra- Adverse Nursing
Name Action indication Reaction Consideration
35
Pyrazinamid Pyrazinamid Anti- 1.8 ml Mechanism Treatment od Active liver Nausea Assessment:
e e tuberculosis unknown, Active disease vomiting Assess
O.D highly specific tuberculosis knowledge/teach
and patient possible
Route: bactericidal for side effects and
P.O Mycobacterium adverse symptoms
Tuberculosis. to report.

Planning:
Give with meals to
decrease gastric
symptoms

Implementation:
Advise the primary
care giver to report
any adverse
reaction.

Evaluation:

Resolution/control
of Tuberculosis
infection supported
by absence of
signs and
symptoms of TB.

Paracetamol

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 Generic Brand Classification Dosage Mechanism of Indication Contra- Adverse Nursing
Name Name Action indication Reaction Consideration
Paracetamol Calpol Para- 1 ml Decreases fever Treatment Hypersensitivity; Stimulation, Assessment:
drops aminophenol by inhibiting the of fever. intolerance to drowsiness, Assess allergic
derivatives/ant PRN effects of tartrazine, nausea, reaction
i pyrogens on alcohol, table vomiting,
Pyretic Q4 hypothalamic sugar, abdominal Planning:
T>37.8 heat regulating saccharin. pain. Give with food to
Celsius center and by reduce gastric
hypothalamic symptom
action leading to
sweating and Implementation:
vasodilations. Advice the primary
Reliefs pain by care giver to report
inhibiting signs of adverse
prostaglandin reaction.
synthesis at the
CNS but do not Evaluation:
have anti-
inflammatory Decrease fever.
action because
of its minimal
effect on
peripheral
prostaglandin
synthesis.

Mupirocin

37
Generic Name Brand Classification Dosage Mechanism of Indication Contra- Adverse Nursing
Name Action indication Reaction Consideration
Mupirocin Bactroban Dermatological Small Binds to Prophylaxis Hypersensitivity Localized Assessment:
s amount on bacterial to prevent burning, 1. Assess for
Anti-bacterials affected isoleucyl bacterial stinging and allergic reaction
area three transfer RNA contamination itching Planning:
times daily synthetase, of small cuts 1. Apply enough
which results and wounds, medication to
in inhibition of abrasions, cover lesions
bacterial incisions, and completely.
protein other clean 2. Apply after
synthesis. lesions. cleansing with
soap, water
before each
application. Dry
well.
Implementation:
1. Instruct the
primary care
giver to report
failure to
improve
condition/infecti
on of skin after
3-5 days.
Evaluation:
Healing of lesions

Salbutamol

38
 Generic Brand Classification Dosage Mechanism of Indication Contra- Adverse Nursing
Name Name Action indication Reaction Consideration
Salbutamol Asmalin Respiratory Drug 1 nebule Stimulates beta-2 Relief of Hypersensitivity Palpitations, Assessment:
Sympathomimetics q8h receptors of bronchospasm tachycardia, 1. Monitor for
bronchioles by in bronchial hypertension, evidence of
increasing levels asthma, nausea, allergic
of cAMP which chronic vomiting, reactions
relaxes the bronchitis. bronchospasm
smooth muscles , cough, Implementation:
to produce heartburn 2. Tell the
bronchodilatation primary care
. giver to stop
drug
immediately if
bronchospas
m occurs.

Evaluation:
Improved airway
exchange

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