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    Anatomy Kidney

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    Herbie Milby
    The kidneys are located near the spine and each contains an outer cortex and inner medulla. The main functional unit of the kidney is the nephron, which filters blood to remove waste and regulate fluid and electrolyte balance. Nephrons filter small molecules from the bloodstream and reabsorb necessary ones, while excess waste is excreted as urine. The kidneys also function as endocrine glands by releasing hormones that regulate red blood cell production and calcium levels.

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    Anatomy Kidney

    Uploaded by

    Herbie Milby
    34 views1 page
    The kidneys are located near the spine and each contains an outer cortex and inner medulla. The main functional unit of the kidney is the nephron, which filters blood to remove waste and regulate fluid and electrolyte balance. Nephrons filter small molecules from the bloodstream and reabsorb necessary ones, while excess waste is excreted as urine. The kidneys also function as endocrine glands by releasing hormones that regulate red blood cell production and calcium levels.

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    The kidneys are located near the spine and each contains an outer cortex and inner medulla. The main functional unit of the kidney is the nephron, which filters blood to remove waste and regulate fluid and electrolyte balance. Nephrons filter small molecules from the bloodstream and reabsorb necessary ones, while excess waste is excreted as urine. The kidneys also function as endocrine glands by releasing hormones that regulate red blood cell production and calcium levels.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    34 views1 page

    Anatomy Kidney

    Uploaded by

    Herbie Milby
    The kidneys are located near the spine and each contains an outer cortex and inner medulla. The main functional unit of the kidney is the nephron, which filters blood to remove waste and regulate fluid and electrolyte balance. Nephrons filter small molecules from the bloodstream and reabsorb necessary ones, while excess waste is excreted as urine. The kidneys also function as endocrine glands by releasing hormones that regulate red blood cell production and calcium levels.

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    The Human Kidney Structure and Function

    The Anatomy and Physiology of the Kidneys

    One of the most complex, beautifully “engineered” organs of the human body, the kidneys perform several essential tasks including the excretion
    of waste products, the maintenance of homeostatic balance in the body and the release of important hormones. To achieve this, human kidneys
    have a highly developed, superbly refined anatomy and physiology.

    Location and Basic Structure of the Kidneys

    The kidneys are located near the vertebral column at the small of the back; the left kidney lying a little higher than the right. Each is identical in
    structure and function. They are bean-shaped, about 10 cm long and 6.5 cm wide. Each kidney comprises an outer cortex and an inner medulla.
    The kidney is supplied with oxygenated blood via the renal artery and drained of deoxygenated blood by the renal vein. In addition, urine
    produced by the kidney as part of its excretory function, drains out via narrow “tubules” and the ureter, in turn connected to the bladder.

    The Nephron

    The main functional unit of the kidney is the nephron. There are approximately one million nephrons per kidney. The role of nephrons is to make
    urine by:

     Filtering blood of small molecules and ions such as water, salt, glucose and other solutes including urea. Large “macromolecules” like
    proteins are untouched.
     Recycling the required quantities of useful solutes which then re-enter the bloodstream. (A process called reabsorption)
     Allowing surplus or waste molecules/ions to flow from the tubules/ureter as urine.

    Filtration and Reabsorbtion in the Kidneys

    During progress through the nephron, some solutes like sodium chloride, potassium and glucose are reabsorbed, along with water, back into the
    bloodstream. This maintains a correct balance of these chemicals within the blood, assisting blood pressure regulation, for example. The filtration
    and reabsorbtion of glucose within the kidneys also helps to maintain correct levels of vital blood sugars. When this regulation breaks down very
    serious health consequences can follow.

    Urea and uric acid are nitrogen containing waste products from metabolic processes in the body. These substances are potentially toxic and are
    partially excreted by the kidneys to maintain good health. Interestingly, of the filtrate which enters each nephron from the blood, only about 1%
    actually leaves the body as urine because of the various reabsorbtion mechanisms driven by osmosis, diffusion, and active transport.

    Tubular Secretion in the Kidneys

    Another, less familiar, mechanism for urine production in the kidneys is tubular secretion. Specialised cells move solutes directly from the blood
    into the tubular fluid. For example, hydrogen and potassium ions are secreted directly into the tubular fluid. This process is “coupled” or balanced
    by the re-uptake of sodium ions back into the blood.

    Tubular secretion of hydrogen ions, augmented by control of bicarbonate levels, is important in maintaining correct blood pH. When the blood is
    too acidic (acidosis) more hydrogen ions are secreted. If the blood becomes too alkaline (alkalosis), hydrogen secretion is reduced. In maintaining
    blood pH within normal limits (about 7.35–7.45) the kidney can produce urine with pH as low as that of acid rain or as alkaline as baking soda!

    The Kidney as an Endocrine Gland

    In addition to its excretory and homeostatic roles, the kidneys also release two important hormones into the blood. These are:

     Erythropoietin which acts on bone marrow to increase the production of red blood cells
     Calcitriol which promotes the absorption of calcium from food in the intestine and acts directly on bones to shift calcium into the
    bloodstream.

    Finally the kidney produces the enzyme renin, an important regulator of blood pressure

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