Final NLEM 2016 PDF
Final NLEM 2016 PDF
Final NLEM 2016 PDF
ESSENTIAL MEDICINES
NEPAL
(FIFTH REVISION)
2016
GOVERNMENT OF NEPAL
MINISTRY OF HEALTH
DEPARTMENT OF DRUG ADMINISTRATION
Background
Essential medicines are those medicines that satisfy the priority health care needs of the
population. WHO published the first essential medicine list in 1977 and has been updating it
every two years since.
Nepal being a signatory of the Alma Ata declaration (1978) implemented the essential medicine
program with a first ever National List of Essential Medicines, NLEM in 1986.
Since then NLEM revised five times (1992, 1997, 2002, 2011 and 2016) with the support from
WHO Nepal.
Criteria of selection
The main criteria for selection of the medicines in the NLEM are public health relevance (harmonizing
with standard treatment schedule use in primary health care service), efficacy, safety, cost-effectiveness
and access.
Methodology/Process Algorithm
Meeting of Main committee (for technical guidance)
Draft committee working as a coordinating task force
Opinions taken from expert groups (therapeutic experts-clinicians and other stakeholders).
Wider consultation through organizing workshop with resource personnel, clinicians/expert,
draft committee, main committee comprising policy makers and programme managers and other
relevant stakeholders based on STG and Evidences
Draft preparation Closer consultation for minor details and edition
Finalization of draft NLEM.
Agenda of DAC for Recommendation
Approval by the ministry
1
Personnel Involved to coordinate and draft the List
Facilitator
Mr. Santosh K.C., Drug Administrator, DDA
Key resource person for overall guidance
Mr. Narayan Prasad Dhakal, Director General, DDA
NEML Draft committee
Mrs. Sangita Shah, Drug Administrator, LMD
Mr. Gorkha Bahadur DC, Pharmacy Officer, DDA
Mr. Rajesh Shrestha, Pharmacy Officer, DDA
Mr. Bhupendra Poudel, Pharmacy Officer, DDA
Mr. Kiran Bajracharya, Pharmacy Officer, DDA
Mr. Bibek Shrestha, Pharmacy Officer, DDA
There were 321 medicines listed in NLEM 2011. A total of 86 medicines have been added or deleted
from the NLEM 2011in the current list. A total of 62 medicines have been added and a total of 24
medicines have been deleted from the previous list. Among the 62 added medicines 56 were added to the
main list and 6 to the complementary list. The medicines added in the Antitubercular and Antiretroviral
groups are added to match with the National TB programme and HIV AIDS Control Program of
Government of Nepal. The new list of NLEM 2016 thus contains 359 medicines.
2
Comparative Table for Addition and Deletion of Molecules in National List of Essential Medicines,
2016
1 Anaesthetics 14 1 1 16
2 Medicines for Pain and Palliative Care 9 2 8***
3 Antihistaminics and Medicines Used in
6
Anaphylaxis 1 1 1 7
4 Antidotes and Other Substances Used in
13
Poisonings 1 12
5 Antiepileptics / Anticonvulsants 7 1 6
6.1 Anthelmintics 4 4
6.2 Antibacterials 45 1 3 1 48
6.3 Antifungal Medicines 3 3
6.4 Antiviral Medicines 17 1 9 25
6.5 Antiprotozoal Medicines 14 2 12
7 Antimigraine Medicines 3 1 2
8 Antineoplastic, Immunosuppressives 34 1 35
9 Antiparkinsonism Medicines 2 2
10 Medicines Affecting the Blood 9 1 10
11 Blood Products and Plasma Substitutes 4 4
12 Cardiovascular Medicines 25 3 12 34
13 Dermatological Medicines 13 2 1 3 13
14 Diagnostic Agents 5 5
15 Disinfectants and Antiseptics 8 2 6
16 Diuretics 5 1 4
17 Gastrointestinal Medicines 13 3 16
18 Hormones, Other Endocrine Medicines
26
and Contraceptives 1 2 27
19 Immunologicals 22 4 26
20 Muscle Relaxants (Peripherally Acting)
4
and Cholinerase Inhibitors 1 5
21 Ophthalmological, Ear, Nose and
22
Throat Preparations 6 1 29
22 Oxytocics and Antioxytocics 5 1 2 6
23 Peritoneal Dialysis Solution 1 1
24 Psychotherapeutic Medicines 15 1 2 16
25 Medicines Acting on the Respiratory
8 1
Tract 1 6
26 Solution Correcting Water, Electrolyte
8
and Acid Base Disturbances 8
3
27 Vitamins and Minerals 8 2 3 9
28 Specific Medicines for Neonatal care 0 2 2
29 Medicines for Diseases of Joint 0 3***
M* = Main list
C** = Complimentary list
***allopurinol, colchicine and methotrexate shifted to new category 29
4
Table showing addition, deletion and medicines whose dose have been changed or shifted to main or complimentary list
Additio Mol
Li n/Deleti ecul Dosage Streng
S.No. Group Name of Drug Dosage form st on e form th Reason
5
tablet, 400 mg, oral liquid 100 To address Paedriatic
Carbamazepine mg/5ml M Addition 0 1 2 patients
To address Paedriatic
Antiepileptics / Valporic acid oral liquid 200 mg/5 ml M Addition 0 1 1 patients
5
Anticonvulsants
Paraldehyde injection, 500 mg/ml C Deletion 1 1 1 Problem with availability
6.1 Anthelmintics
Niclosamide tablet, 500 mg M Shift 0 0 0
6
Isoniazid +
rifampicin + To address National TB
pyrazinamide tablet, injection M Change 0 0 1 Programme
Isoniazid + To address National TB
rifampicin tablet, injection M Change 0 0 1 Programme
To address National TB
Bedaquiline tablet, 100 mg M Addition 1 1 1 Programme
To address National TB
Pyrazinamide sachet M Change 0 0 1 Programme
Isoniazid +
rifampicin+ Not in WHO model list of
pyrizinamide tablet 30+60+150 M Deletion 1 1 1 essential drugs
Antifungal
6.3
Medicines
7
To address National
Nevirapine capsule 50 mg M Addition 0 1 1 Programme
To address National
Ritonavir tablet 100 mg M Addition 1 1 1 Programme
Abacavir/lamiv To address National
udine tablet 60/30 mg M Addition 1 1 1 Programme
Emtricitabine/t To address National
enofovir tablet, 200/300 mg M Addition 1 1 1 Programme
Lopinavir/riton To address National
avir tablet, 100/25 mg M Addition 1 1 1 Programme
Zidovudine/lam To address National
ivudine tablet, 60/30 mg M Addition 1 1 1 Programme
Zidovudine/lam
ivudine/nevirap To address National
ine tablet, 60/30/50 M Addition 1 1 1 Programme
Diloxanide
Antiprotozoal tablet, 500 mg M Deletion 1 1 1 Problem with availability
6.5
Medicines
Paromomycin
injection, 750 mg M Deletion 1 1 1 Problem with availability
Antimigraine
7 Ergometrine
Medicines tablet 1 mg M Deletion 1 1 1 Not preferred drugs
Etoposide
tablet, 100 mg M Addition 0 1 1 Oral form addition
Antineoplastic,
8 Immunosuppress Methotrexate
ives tablet, 5,10 mg M Addition 0 0 2 Dosage form addition
Procarbazine
tablet, 50 mg M Addition 1 1 1 Increase coverage
8
Bleomycin
powder for injection, 15 mg M Shift 0 0 0
Medicines
10 Affecting the Enoxaparin INR monitoring not
Blood injection 30,60,80 mg M Addition 1 1 3 needed as heparin
Metoprolol
tablet, 12.5/25/50 mg M Addition 1 1 3 Safter than atenolol
Metoprolol
12.5/25/50 mg M Addition 1 1 3 Safter than atenolol
Amiodarone
tablet 100 mg, injection
50mg/ml M Addition 1 2 2 Preferred choice
9
For hypertensive
Labetalol emergencies in
injection, 5 mg/ml M Addition 1 1 1 pregnancies
Enalapril
tablet, 5,10,20 mg M Deletion 1 1 3 Replaced with ramipril
Ramipril
tablet, 2.5, 5 mg M Addition 1 1 2 Replaced for enalapril
Frusemide
tablet, 20/40 mg, injection
10mg/ml M Addition 1 2 3 Preferred choice
Spirolactone
tablet 25 mg M Addition 1 1 1 Preferred choice
10
Formaldehyde
solution 3% M Deletion 1 1 1 Phased out
Ethinylestradiol
+levonorgestrel
20/1000 mcg* M Addition 0 0 1 Low therapeutic dosage
Silicon ring
pessaries M Addition 1 1 1 Preferred choice
Hormones, Other Gibenclamide Not preferred choice of
Endocrine tablet, 2.5, 5 mg M Deletion 1 1 2 drug
18
Medicines and Common Cost effective
Contraceptives Glicazide
tablet, 40, 80 mg M Addition 1 1 2 drug
Metformin
tablet 850 mg M Addition 0 0 1 Increase the range
Levothyroxine
tablet, 25,50,75 mcg M Addition 0 0 3 Increase the range
Diphtheria Request from health
19 Immunologicals
antitoxin M Addition 1 1 1 services
11
Rotavirus Request from health
M Addition 1 1 1 services
21
l, Ear, Nose and
Ofloxacin eye drop 0.3 % To incease antibacterial
Throat C Addition 1 1 1 range
Preparations
Ciprofloxacin drop 0.3% To increase antibacterial
M Addition 1 1 1 range
Isoxsuprine
injection 5mg/ml Safer alternative
Oxytocics and hydrochloride
22 M Deletion 1 1 1 available
Antioxytocics
Nefedipine capsule 10 mg
M Addition 1 1 1 Safer in pregnancy
12
Terbutaline injection, 0.5 mg/ml
M Addition 1 1 1 Common choice
13
Calcium tablet 500 mg M Addition 1 1 1 Single mineral
14
National List of Essential Medicines, 2016
Main List Complementary List Dosage Form
1. Anaesthetics
1.1 General Anaesthetics and Oxygen
Halothane inhalation
Isoflurane inhalation
Ketamine injection, 50 mg/ml (as hydrochloride) in 10-ml
vial
Nitrous oxide inhalation
Oxygen inhalation (medicinal gas)
Thiopental powder for injection, 0.5g, 1.0g (sodium salt) in
ampoule
Propofol injection, 10mg/ml in 20-ml ampoule
Sevoflurane inhalation
1.2 Local Anaesthetics
Bupivacaine injection, 0.25%, 0.5% (hydrochloride) in vial
Lidocaine (lignocaine) injection, 1%, 2% (hydrochloride) in vial;
injection for spinal anaesthesia, 5%
(hydrochloride) in 2-ml ampoule to be mixed
with 7.5% glucose solution
Lidocaine (lignocaine) + epinephrine (adrenaline) injection, lignocaine 2% (hydrochloride) +
epinephrine 1:200 000, in vial
Ephedrine* injection, 30 mg (hydrochloride)/ml in 1-ml
ampoule
*For use in spinal anaesthesia during delivery, to prevent hypotension
1.3 Preoperative Medication and Sedation for Short-term Procedures
Atropine injection, 1 mg (sulfate) in 1-ml ampoule
Diazepam injection, 5mg/ml in 2-ml ampoule
Midazolam injection, 1mg/ml, 5mg/ml with/out preservative
Morphine injection, 10 mg (sulfate or hydrochloride) in 1-
ml ampoule
2 Medicines for Pain and Palliative Care
2.1. Non-opioid Analgesics & NSAIMs
Ibuprofen tablet, 200 mg, 400 mg, Oral liquid, 100 mg/5ml
Paracetamol tablet, 500mg; injection, 150 mg/ml in 2-ml
ampoule, 10 mg/ml in 100 ml bottle; suspension,
125 mg/5ml
Aspirin tablet, 500 mg
Diclofenac Sodium tablet, 50 mg, injection 25 mg/ml
2.2. Opioid Analgesics
Codeine tablet, 30 mg (as phosphate)
Fentanyl injection, 50mcg/ml
Morphine injection, 10 mg (sulfate or hydrochloride) in 1-
ml ampoule; tablet, 10 mg; prolonged release
tablet, 10 mg, 30 mg, 60 mg (sulfate); oral liquid
10 mg/5ml (sulfate)
Pethidine injection, 50 mg (hydrochloride) in 1-ml
ampoule
3 Antihistaminics and Medicines Used in Anaphylaxis
Cetirizine tablet 10 mg,
Dexamethasone injection, 4 mg dexamethasone phosphate (as
disodium salt) in 1-ml ampoule
Epinephrine (adrenaline) injection, 1mg (as hydrochloride or acid tartrate)
in 1-ml ampoule
Hydrocortisone powder for injection, 100 mg (as sodium
succinate) in vial
Pheniramine tablet, 25, 50 mg, injection, 22.75 mg (maleate)
/ml
Prednisolone tablet, 5mg
Fexofenadine oral Solution, 30mg/5 ml
4 Antidotes and Other Substances Used in Poisonings
4.1 Non-Specific
Charcoal, activated powder; oral liquid (sorbitol-base slurry)
4.2 Specific
Atropine injection, 1 mg (sulfate) in ampoule; powder for
injection 50 mg (sulfate) in vial
Dimercaprol injection in oil, 50 mg/ml in 2-ml ampoule
Naloxone injection, 400 mcg (hydrochloride) in 1-ml
ampoule
Pralidoxime injection, 500 mg or 1 g (mesilate, chloride or
iodide) in ampoule
Acetylcysteine injection, 200 mg/ml in 10-ml ampoule
Calcium gluconate injection, 100 mg/ml in 10-ml ampoule
Deferoxamine powder for injection, 500 mg (mesilate) in vial
Methylthioninium chloride injection, 10 mg/ml in 10-ml ampoule
(Methylene blue)
Potassium ferric hexacyano- powder for oral administration
ferrate (II).2H2O (Prussian
blue)
Sodium calcium edetate injection, 200 mg/ml in 5 ml ampoule
Sodium nitrite injection, 30 mg/ml in 10-ml ampoule
5. Antiepileptics / Anticonvulsants
Carbamazepine tablet, 100, 200 mg, 400 mg, Oral liquid
100mg/5ml
Diazepam injection, 5mg/ml in 2- ml ampoule (intravenous
or rectal)
Magnesium sulfate* injection, 500 mg/ml in 2-ml ampoule.
* For use in eclampsia and severe pre-eclampsia and not for other convulsant disorders.
Phenobarbital tablet, 15 mg, 30 mg, injection 200mg/ml
Phenytoin capsule or tablet, 25 mg, 50 mg, 100 mg (sodium
salt); injection, 50 mg /ml (sodium salt) in 5-ml
vial
Valproic acid tablet (enteric coated), 200 mg (sodium salt),
Oral liquid 200mg/5ml
6 Anti-infective Medicines
6.1 Anthelmintics
6.1.1 Intestinal Anthelmintics
Albendazole tablet (chewable), 400 mg
Niclosamide tablet (chewable), 500 mg
Praziquantel tablet, 150 mg, 600 mg
6.1.2 Antifilarials
Diethylcarbamazine tablet, 50 mg, 100 mg (dihydrogen citrate)
6.2 Antibacterials
6.2.1 Beta-lactam medicines
Amoxicillin capsule or tablet, 250 mg, 500 mg (as trihydrate);
dispersible tablet 125 mg (as trihydrate), powder
for oral liquid, 125 mg/1ml
Ampicillin powder for injection, 500 mg (sodium salt)
Benzathine benzylpenicillin powder for injection, 600 000 IU, 1200 000 IU,
2400 000 IU in vial
Benzylpenicillin (Penicillin G) powder for injection, 300 mg (0.5 million IU),
600 mg (1 million IU) (as sodium or potassium
salt) in vial
Cephalexin Capsule 250 mg (as monohydrate), Oral liquid
125/5 ml, 250/5 ml (anhydrous)
Cefixime tablet, 200,400* mg
*only listed for single-dose treatment of uncomplicated ano-genital gonorrhoea
Cloxacillin capsule, 250 mg, 500 mg; powder for oral liquid,
125 mg / 5ml; powder for injection, 500 mg (as
sodium salt) in vial
Phenoxymethylpenicillin (Penicillin V) tablet, 250 mg (as potassium salt); powder for
oral liquid, 250 mg/5 ml (as potassium salt)
Procaine benzylpenicillin powder for injection, 300,000 IU in vial
Cefazolin* powder for injection, 1g (as sodium salt) in vial
*For surgical prophylaxis
Ceftriaxone powder for injection, 250 mg (as sodium salt) in
vial
6.2.2 Other Antibacterials
Azithromycin capsule or tablet 250 mg, 500 mg; oral liquid,
200 mg /5ml.
Chloramphenicol capsule, 250 mg, 500 mg; oral liquid, 125 mg /
5ml (as palmitate); powder for injection, 1g (as
sodium succinate) in vial
Ciprofloxacin tablet, 250 mg, 500 mg (as hydrochloride)
Doxycycline capsule, 100 mg (as hydrochloride)
Gentamicin injection, 10 mg, 40 mg / ml (as sulfate) in 2-ml
vial
Metronidazole tablet, 200 mg, 400 mg; injection, 500 mg in
100-ml bottle; oral liquid, 100 mg, 200 mg (as
benzoate) / 5ml
Nitrofurantoin tablet, 100 mg
Sulfamethoxazole+Trimethoprim dispersible tablet, 100mg+20 mg, 200 mg+ 40
mg; tablet 400 mg + 80 mg, 800 mg + 160 mg;
oral liquid, 200mg + 40mg /5ml
Erythromycin tablet, 250 mg (stearate); oral liquid, 250 mg /
5ml (stearate)
Nalidixic acid tablet, 250 mg, 500 mg
Tetracycline capsule 250 mg, 500 mg (as hydrochloride)
Vancomycin powder for inj. 250 mg (as hydrochloride) in vail
6.2.3 Antileprosy Medicines
Clofazimine capsule, 50 mg, 100 mg
Dapsone tablet, 50 mg, 100 mg
Rifampicin capsule or tablet 150 mg, 300 mg
(For the treatment of leprosy, combination therapy is essential to prevent the emergence of drug
resistance)
6.2.4 Antitubercular Medicines
Ethambutol tablet, 100 mg, 400 mg, 600 mg (hydrochloride)
Ethambutol + Isoniazid tablet, 400mg + 150mg
Ethambutol + Rifampicin +Isoniazid tablet, 275 mg + 150 mg+ 75 mg
Ethambutol + Rifampicin +Isoniazid+ Pyrazinamide tablet, 275 mg+150 mg+ 75 mg + 400 mg
Isoniazid tablet, 50mg, 100 mg, 300 mg
Isoniazid + Rifampicin tablet, 60 mg+60 mg, 50 mg+75mg, 75 mg +
150mg
Isoniazid + Rifampicin + Pyrazinamide tablet, 30 mg+ 60 mg+150 mg, 50 mg+75
mg+150 mg
Rifampicin capsule or tablet, 150mg, 300mg, 450 mg
Streptomycin powder for injection, 1 g (as sulfate) in vial
Complementary list: Second-line medicines for the treatment of multi-drug resistant tuberculosis (MDR-
TB) – to be made available only in specialised centres adhering to standard treatment protocol.
Amoxicillin + Clavulanic tablet, 500 mg + 125 mg, 875 mg+125 mg
acid
Bedaquiline tablet, 100mg
Capreomycin powder for injection, 1 g in vial
Clofazimine capsule, 100 mg
Cycloserine capsule, 250 mg
Ethionamide tablet, 125, 250 mg
Kanamycin powder/solution for injection 1 g in vial/
ampoule
Levofloxacin* tablet, 250 mg, 500 mg
Linezolid tablet 300 mg
Moxifloxacin* tablet, 400 mg
Ofloxacin* tablet, 200 mg
*To be decided based on availability and programme considerations.
P-aminosalicylic acid (PAS) granules, 4 g, 9.2 g in sachet; tablet 500 mg
Pyrazinamide tablet, 150 mg, 400 mg, 500 mg
6.3 Antifungal Medicines
Clotrimazole cream, 1%; pessary 100 mg, mounth paint
1%w/v
Fluconazole capsule or tablet, 150 mg
Nystatin oral liquid 50 mg/5 ml, 100000IU/ml mouth
paint
6.4 Antiviral Medicines
6.4.1 Antiherpes Medicines
Aciclovir powder for injection 250 mg (as sodium salt) in
vials; tablet 200/400/800 mg
6.4.2 Antiretrovirals
6.4.2.1 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors
Abacavir (ABC) tablet, 300 mg (as sulfate); oral liquid, 100 mg
(as sulfate)/5ml
Lamivudine (3TC) tablet, 150 mg; oral liquid 50 mg/5ml
Stavudine (d4T) capsule, 15 mg, 20 mg, 30 mg; powder for oral
liquid, 5 mg/5ml
Tenofovir disoproxil fumarate (TDF) tablet, 300 mg (equivalent to 245 mg tenofovir
disoproxil)
Zidovudine (ZDV or AZT) capsule, 100 mg; tablet 300 mg; oral liquid 50
mg/ 5ml
6.4.2.2 Non-nucleoside Reverse Transcriptase Inhibitors
Efavirenz (EFV or EFZ) capsule, 200 mg; tablet, 600 mg
Nevirapine (NVP) tablet, 200 mg; oral liquid, 50 mg/5ml, 50 MG
6.4.2.3 Protease Inhibitors
Indinavir (IDV) capsule, 400 mg (as sulfate)
Lopinavir + Ritonavir (LPV/r) capsule 200 mg + 50 mg
Nelfinavir (NFV) tablet, 250 mg (as mesilate)
Ritonavir tablet100 mg
Saquinavir (SQV) +Ritonavir oral dosage form, 1g+100 mg
6.4.2.4 Fixed-dose Combination
Abacavir + Lamivudine tablet, 60mg + 30 mg
Emtricitabine + Tenofovir tablet, 200mg + 300 mg
Lamivudine + Stavudine tablet, 150 mg + 30 mg
Lopinavir + Ritonavir tablet, 100 mg + 25 mg
Stavudine + Lamivudine + Nevirapine tablet, 30 mg + 150 mg + 200 mg
Zidovudine + Lamivudine tablet, 60 mg + 30 mg, 300 mg + 150 mg
Zidovudine + Lamivudine + Nevirapine tablet, 60 mg + 30 mg + 50 mg, 300 mg + 150
mg + 200 mg
6.4.3 Other antiviral
Entecavir tablet 0.5, 1 mg
Oseltamivir Capsule, 30/45/75 mg as phosphate, Oral powder
6 mg/ml
Sofosbuvir tablet 400 mg
6.5 Antiprotozoal Medicines
6.5.1 Antiamoebic and Antigiardiasis Medicines
Metronidazole tablet, 200mg, 400mg; oral liquid, 200 mg (as
benzoate) / 5 ml.
Tinidazole tablet, 500mg
6.5.2 Antileishmaniasis Medicines
Miltefosine capsule, 50 mg
Amphotericin B powder for injection, 50 mg in vial (as
deoxycholate or liposomal)
Sodium stibogluconate injection, 100mg/ml
6.5.3 Antimalarial Medicines
Artemether* oily injection, 80 mg/ml in 1-ml ampoule.
* For use in the management of severe malaria.
Artemether+lumefantrine* tablet, 20 mg+ 120 mg
* Not recommended in the first trimester of pregnancy or in children below 5 kg.
Artesunate injection, ampoules, containing 60 mg anhydrous
artesunic acid with a separate ampoule of 5%
sodium bicarbonate solution; tablet 50 mg
(To be used in combination with Sulfadoxine + Pyrimethamine.)
Chloroquine tablet, 150 mg base (as phosphate or sulfate);
oral liquid, 50 mg / 5ml (as phosphate or sulfate);
injection, 40mg /ml in 5- ml ampoule (as
phosphate, sulfate or hydrochloride)
Primaquine tablet, 7.5 mg, 15 mg (as diphosphate)
Sulfadoxine + Pyrimethamine tablet, 500 mg + 25 mg
(To be used only in combination with Artesunate.)
Quinine tablet, 300 mg (as bisulfate or sulfate); injection,
300 mg (as dihydrochloride)/ ml in 2-ml
ampoule.
7 Antimigraine Medicines
7.1 For Treatment of Acute Attack
Paracetamol tablet, 500 mg
7.2 For Prophylaxis
Propranolol tablet 20 mg, 40 mg (hydrochloride)
8 Antineoplastic, Immunosuppressives and Medicines Used in Palliative Care
8.1 Immunosuppressive Medicines
Cyclosporin capsule 25 mg
8.2 Cytotoxic Medicines
Calcium folinate (Calcium leucovorin) tablet, 15 mg
Chlorambucil tablet, 2 mg, 5 mg
Cisplatin powder for injection, 10 mg, 50 mg in vial.
Cyclophosphamide tablet, 25 mg; powder for injection, 200 mg, 500
mg, 1 g in vial
Cytarabine injection 100 mg, 500 mg in vial
Dacarbazine powder for injection, 100 mg in vial
Dactinomycin powder for injection, 500 mcg in vial
Daunorubicin powder for injection 20 mg (as hydrochloride) in
vial
Doxorubicin powder for injection, 10 mg, 50 mg in vial
Epirubicin injection, 10 mg, 50 mg (hydrochloride) in vial
Etoposide tablet, 100 mg, injection 20 mg/ml in 5-ml
ampoule
Fluorouracil injection 50 mg/ml in 5-ml, 10-ml ampoule
Hydroxy urea capsule 500 mg
Ifosfamide + Mesna injection, 1g + 200 mg, in vial
Lomustine capsule, 40 mg
Melphalan tablet, 2 mg, 5 mg; powder for injection, 50mg in
vial
Mercaptopurine tablet, 50 mg
Methotrexate tablet, 2.5/5/10 mg (as sodium salt); powder for
injection 15 mg, 50 mg (as sodium salt) in vial
Mitomycin powder for injection, 2mg, 10mg, 20mg in vial
Mitoxantrone injection, 2 mg/ml in 10ml ampoule
Procarbazine capsule 50 mg (as hydrochloride)
Vinblastine powder for injection 10 mg (sulfate) in vial
Vincristine powder for injection, 1 mg (sulfate) in vial
Bleomycin powder for injection, 15mg (as sulfate) in vial
Carboplatin injection 150 mg, 450 mg in vial
8.3 Hormones and Antihormones
Hydrocortisone powder for injection, 100 mg (as sodium
succinate) in vial
Tamoxifen tablet, 20 mg (as citrate)
Bicalitumide tablet or capsule 50 mg
Dexamethasone Dexamethasone phosphate 4 mg /ml (as sodium
salt) in 2-ml ampoule
Prednisolone tablet, 5 mg, 10 mg, 20 mg
8.4 Miscellaneous
Granulocyte Colony Stimulating Factor (GCSF) injection, 30 million unit in vial
Interferon injection, 5 million units/ml in vial
L-Asparaginase injection, 5 000 IU, 10 000 IU in vial
Ondansetron injection, 2 mg/ml (as hydrochloride) in 2-ml, 4-
ml vial; tablet 2mg, 4mg (as hydrochloride)
9 Antiparkinsonism Medicines
Levodopa + Carbidopa tablet, 100 mg + 10 mg, 250 mg + 25 mg
Trihexyphenidyl (benzhexol) tablet, 2 mg (hydrochloride)
10 Medicines Affecting the Blood
10.1 Antianaemia Medicines
Ferrous sulfate* tablet, equivalent to 60 mg iron; oral liquid,
equivalent to 25 mg iron/ ml
Ferrous sulfate*+Folic acid tablet, equivalent to 60 mg Iron+ 400 mcg Folic
acid, oral drop.
*Ferrous fumarate may be used
Folic acid tablet, 5mg
Iron Dextran injection, equivalent to 50 mg iron/ml in 2-ml
ampoule
10.2 Medicines Affecting Coagulation
Enoxaparin injection 30mg/0.3ml, 60mg/0.6ml, 80mg/0.8ml
Heparin sodium injection, 1000 IU/ml, 5000 IU/ml,20000IU/ml
in 1-ml ampoule
Phytomenadione injection, 10mg /ml in 5-ml ampoule; tablet 10
mg
Protamine sulfate injection, 10mg/ml in 5-ml ampoule
Warfarin tablet, 1 mg, 2 mg, 5 mg (sodium salt)
Acenocoumarol tablet, 1mg
11 Blood Products and Plasma Substitutes
11.1 Plasma Substitutes
Albumin, human injectable solution, 20 or 25%
Polygeline injectable solution, 3.5%
11.2 Plasma Fractions For Specific Use
Factor VIII Concentrate dried concentrate
Factor IX complex dried concentrate
12 Cardiovascular Medicines
12.1 Antianginal Medicines
Glyceryl trinitrate tablet (sublingual), 500 mcg
Isosorbide dinitrate tablet (sublingual), 5 mg, 10 mg
Metoprolol tablet, 12.5,25,50 mg
Verapamil tablet, 40 mg, 80 mg (hydrochloride); injection,
2.5 mg / ml in 2-ml ampoule
12.2 Antiarrhythmic Medicines
Amiodarone tablet 100 mg, injection 50mg/ml
Digoxin tablet, 62.5 mcg, 250 mcg; oral liquid, 50 mcg /
ml; injection, 250 mcg / ml in 2-ml ampoule
Epinephrine (Adrenaline) 100 mcg/ml (as acid tartrate or hydrochloride) in
10 ml ampoule
Isoprenaline injection, 1 mg (hydrochloride)/ml in vial
Lidocaine (Lignocaine preservative free) injection 2 % (hydrochloride) in vial
Metoprolol tablet, 12.5,25,50 mg
Disopyramide capsule, 100 mg, 150 mg
Procainamide tablet, 250 mg (hydro- chloride); injection, 100
mg /ml in 10-ml ampoule
12.3 Antihypertensive Medicines
Amlodipine tablet 2.5, 5 mg
Atenolol tablet 25, 50,100 mg
Enalapril tablet, 5 mg, 10 mg, 20 mg
Hydralazine injection 20 mg
Hydrochlorothiazide tablet, 25 mg, 50 mg
Labetalol injection 5 mg/ml 20 ml
Losartan tablet, 25, 50mg
Methyldopa* tablet, 250 mg
* Listed for the use in the management of pregnanacy induced hypertention only
Nifedipine sustained release tablet, 10 mg, 20 mg
Prazosin sustained release tablet 500 mcg, 1mg (mesilate)
Sodium nitroprusside powder for infusion, 50 mg in ampoule
12.4 Medicines Used in Heart Failure
Digoxin tablet, 62.5 mcg, 250 mcg; oral liquid, 50 mcg /
ml; injection, 250 mcg / ml in 2-ml ampoule
Furosemide injection, 10 mg/ml in 2ml ampoule. tablet, 20,
40 mg
Ramipril tablet 2.5, 5 mg
Spironolactone tablet, 25 mg
Dobutamine injection, 12.5 mg/ml (as hydrochloride) in 20-
ml ampoule
Dopamine injection 40mg/ml (hydrochloride) in 5- ml vial
12.5 Antithrombotic Medicines
Aspirin tablet, 50mg, 75 mg, 100mg
Clopidogrel tablet 75 mg
Streptokinase injection 750000 IU, 1500 000 IU in vial
12.6 Lipid Lowering Agent
Atorvastatin tablet, 10 mg, 20 mg (as calcium trihydrate)
Fenofibirate tablet, 80, 160 mg
13 Dermatological Medicines
13.1 Antifungal Medicines
Benzoic acid + Salicylic acid ointment or cream, 6% + 3%
Clotrimazole cream, 1%
Fluconazole capsule 150 mg
13.2 Anti-infective Medicines
Mupirocin 2 % cream/ont
Povidone iodine solution, 5%
Silver sulfadiazine cream, 0.2%
Gentian violet
(Methylrosanilinium
chloride) aqueous solution 1%
13.3 Anti-inflammatory and Antipruritic Medicines
Betamethasone ointment or cream, 0.1% (as valerate)
Calamine lotion lotion, 15%
Hydrocortisone ointment or cream, 1% (acetate)
13.4 Medicines Affecting Skin Differentiation and Proliferation
Benzoyl peroxide cream or lotion, 5%
Salicylic acid cream10, 20, 40%
13.5 Scabicides and Pediculicides
Permethrin lotion 1%, cream 5%
14 Diagnostic Agents
14.1 Ophthalmic Medicines
Fluorescein eye drops, 1%, 2% (sodium salt); injection, 10%,
20% (sodium salt) in 5-ml ampoule
14.2 Radiocontrast Media
Amidotrizoate injection, 140-420 mg iodine/ml (as sodium or
meglumine salt) in 20, 50 ml ampoule
Barium sulfate 100-250% w/v in aqueous suspension
Iohexol injection, 140-350 mg iodine/ml in 10/20 ml
ampoule
Meglumine iotroxate solution, 5-8 g iodine in 100-250 ml
15 Disinfectants and Antiseptics
15.1 Antiseptics
Chlorhexidine solution, 5% (digluconate) for dilution, solution*
or ointment, 4 %
*Only for umbilical cord stump care
Gentian violet (Methylrosanilinium chloride) aqueous solution, 1%
(Powder may be supplied for preparation of solution at the health facility)
Povidone iodine solution, 5%, 10 % w/v
Rectified spirit liquid (90 % v/v)
15.2 Disinfectants
Chlorine based compound powder, (0.1% available chlorine) for solution
Glutaraldehyde solution, 2%
16 Diuretics
Furosemide tablet, 40 mg; injection, 10 mg/ml in 2-ml
ampoule
Hydrochlorothiazide tablet, 25mg, 50 mg
Mannitol injectable solution, 10%, 20%
Spironolactone tablet, 25 mg, 100 mg
17 Gastrointestinal Medicines
17.1 Antacids and Other Anti-ulcer Medicines
Dried aluminium hydroxide gel + Magnesium tablet, 250 mg + 250 mg
hydroxide*
(*Tablet containing Magnesium trisilicate 500 mg may be used.)
Ranitidine tablet, 150 mg, 300 mg (as hydrochloride);
injection 25 mg/ml in 2-ml ampoule
Omeprazole capsule, 20 mg
17.2 Antiemetic Medicines
Granisetron tablet 1, 2 mg
Metoclopramide tablet, 10 mg (hydrochloride); injection, 5 mg
(hydrochloride)/ml in 2-ml ampoule
Promethazine tablet, 25 mg (theoclate); oral liquid, 5 mg
(hydrochloride)/ 5ml;injection, 25 mg
(hydrochloride) / ml in 2-ml ampoule
17.3 Anti-inflammatory Medicines
Sulfasalazine tablet, 500 mg
17.4 Laxatives
Lactulose solution, 3.35 mg / 5ml
Magnesium sulfate powder, 500 g
Bisacodyl tablet, 10 mg
Ispaghula husk oral powder
17.5 Medicines Used in Diarrhoea
17.5.1 Oral Rehydration
Oral rehydration salts* sachet containing: Dextrose, anhydrous 13.5 g,
Sodium chloride 2.6 g, Potassium chloride 1.5 g,
Trisodium citrate dihydrate 2.9g, appropriate
flavour q.s. Dissolved to produce 1 litre,
provides dextrose 75mEq, sodium 75 mEq or
mmol/l, chloride 65 mEq or mmol/l, potasium 20
mEq or mmol/l, citrate 10 mmol/l and osmolarity
245 mOsm/l
* In case of cholera a higher concentration of sodium may be required.
17.5.2 Medicine for Diarrhoea in Children
Zinc sulfate* dispersible tablet, equivalent to Zinc 10 mg, 20
mg (scored)
* In acute diarrhoea, zinc sulfate should be used as an adjunct to oral rehydration salts
Zinc sulfate oral solution, 10 mg/5ml in 50- ml bottle
17.6 Antispasmodic Medicines
Hyoscine butylbromide tablet, 10 mg, 20 mg; injection, 20 mg/ml in 1-ml
ampoule
Drotaverine hydrochloride tablet 40/80 mg
18.3 Contraceptives
18.3.1 Oral Harmonal Contraceptives
Ethinylestradiol + Levonorgestrel tablet, 30 mcg +150 mcg, 20 mcg +1.0 mg.
Ethinylestradiol + Norethisterone tablet, 35 mcg + 1.0 mg,
Levonorgestrel tablet, 750 mcg (pack of two), 1.5 mg)
18.3.2 Injectable Hormonal Contraceptive
Medroxyprogesterone acetate depot injection, 150 mg / ml in 1-ml vial
18.3.3 Intrauterine Devices
Copper-containing devices
18.3.4 Barrier Methods
Condoms
18.3.5 Implantable Contraceptives
Hormoal intrauterine device – multiple advantages
Intrauterine device with progestogen
Levonorgestrel-releasing implant two-rod levonorgestrel-releasing implant, each
rod containing 75 mg of levonorgestrel (150 mg
total)
18.3.6 Miscellaneous
Ring pessary
Silicon ring pessary
18.4 Estrogens
Ethinylestradiol tablet, 50 mcg
18.5 Insulins and Other Antidiabetic Agents
Gliclazide tablet 40,80 mg
Insulin (soluble injection, 40 IU / ml in 10- ml vial
Intermediate acting insulin injection, 40 IU / ml in 10- ml vial (as compound
insulin zinc suspension or isophane insulin)
Metformin tablet, 500 mg (hydrochloride), 850 mg
Glipizide tablet, 2.5 mg, 5 mg