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Final NLEM 2016 PDF

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NATIONAL LIST OF

ESSENTIAL MEDICINES
NEPAL
(FIFTH REVISION)
2016

GOVERNMENT OF NEPAL
MINISTRY OF HEALTH
DEPARTMENT OF DRUG ADMINISTRATION
Background
 Essential medicines are those medicines that satisfy the priority health care needs of the
population. WHO published the first essential medicine list in 1977 and has been updating it
every two years since.
 Nepal being a signatory of the Alma Ata declaration (1978) implemented the essential medicine
program with a first ever National List of Essential Medicines, NLEM in 1986.
 Since then NLEM revised five times (1992, 1997, 2002, 2011 and 2016) with the support from
WHO Nepal.

Criteria of selection
The main criteria for selection of the medicines in the NLEM are public health relevance (harmonizing
with standard treatment schedule use in primary health care service), efficacy, safety, cost-effectiveness
and access.

Methodology/Process Algorithm
 Meeting of Main committee (for technical guidance)
 Draft committee working as a coordinating task force
 Opinions taken from expert groups (therapeutic experts-clinicians and other stakeholders).
 Wider consultation through organizing workshop with resource personnel, clinicians/expert,
draft committee, main committee comprising policy makers and programme managers and other
relevant stakeholders based on STG and Evidences
 Draft preparation Closer consultation for minor details and edition
 Finalization of draft NLEM.
 Agenda of DAC for Recommendation
 Approval by the ministry

Main committee (technical guidance)


 Honorable Health Minister (MOH)
 Secretary, Ministry of Health (MOH)
 Chief, Policy, Planning and International Cooperation Division (MOH)
 Chief, Public Health Administration, Monitoring and Evaluation Division (MOH)
 Chief, Curative division (MOH)
 Director, Department of Health Services (DoHS)
 Director, Logistic Management Division (DoHS)
 Director, Primary Health Care Revitalization Division (DoHS)
 Director, National Tuberculosis Center (DoHS)
 Director, National AIDs and STD Control Centre (DoHS)
 Director, Epidemiology and Disease Control Division, (DoHS)
 Director, Child Health Division (DoHS)
 Director, National Medicine Laboratory (MOH)
 Director, Leprosy Control Section (DoHS)
 Director, Family Health Division (DoHS)
 Director, Management Division (DoHS)
 Director, Department of Ayurveda
 Chairperson, Nepal Medical Council
 WR/WHO

1
Personnel Involved to coordinate and draft the List
Facilitator
 Mr. Santosh K.C., Drug Administrator, DDA
Key resource person for overall guidance
 Mr. Narayan Prasad Dhakal, Director General, DDA
NEML Draft committee
 Mrs. Sangita Shah, Drug Administrator, LMD
 Mr. Gorkha Bahadur DC, Pharmacy Officer, DDA
 Mr. Rajesh Shrestha, Pharmacy Officer, DDA
 Mr. Bhupendra Poudel, Pharmacy Officer, DDA
 Mr. Kiran Bajracharya, Pharmacy Officer, DDA
 Mr. Bibek Shrestha, Pharmacy Officer, DDA

Criteria for inclusion of a medicine in NLEM will be as follows:


 Approved/licensed medicine in the country
 Relevance for disease posing public health problem (morbidity)
 Proven efficacy and safety profile based on valid scientific evidence (evidence-based)
 Cost effective
 Aligned with STG (the current treatment guidelines under public health program)
 Stable under the storage conditions
 Preference on relative safety, efficacy, cost-effectiveness (in case there are more than one
alternative)
 Fixed Dose Combinations (FDCs) with unequivocally proven advantage over Single (in terms of
increasing efficacy, reducing adverse effects and/or improving compliance)
 Access, free drug, SHI

Criteria for deletion of a medicine from NLEM will be as follows:


 Banned in Nepal
 Reports of concerns on the safety profile of a medicine
 If better efficacy or favorable safety profiles and better cost-effectiveness is available.
 Irrelevant to public health disease burden
 Antimicrobial resistance pattern (In case of antimicrobials, if the resistance pattern has rendered a
medicine ineffective in Nepalese and international context)
 Medicine with abuse and misuse potential

There were 321 medicines listed in NLEM 2011. A total of 86 medicines have been added or deleted
from the NLEM 2011in the current list. A total of 62 medicines have been added and a total of 24
medicines have been deleted from the previous list. Among the 62 added medicines 56 were added to the
main list and 6 to the complementary list. The medicines added in the Antitubercular and Antiretroviral
groups are added to match with the National TB programme and HIV AIDS Control Program of
Government of Nepal. The new list of NLEM 2016 thus contains 359 medicines.

2
Comparative Table for Addition and Deletion of Molecules in National List of Essential Medicines,
2016

S.No. Therapeutic Category Total Deleted Added Total


(NLEM (NLEM
2011) 2016)
M* C** M* C**

1 Anaesthetics 14 1 1 16
2 Medicines for Pain and Palliative Care 9 2 8***
3 Antihistaminics and Medicines Used in
6
Anaphylaxis 1 1 1 7
4 Antidotes and Other Substances Used in
13
Poisonings 1 12
5 Antiepileptics / Anticonvulsants 7 1 6
6.1 Anthelmintics 4 4
6.2 Antibacterials 45 1 3 1 48
6.3 Antifungal Medicines 3 3
6.4 Antiviral Medicines 17 1 9 25
6.5 Antiprotozoal Medicines 14 2 12
7 Antimigraine Medicines 3 1 2
8 Antineoplastic, Immunosuppressives 34 1 35
9 Antiparkinsonism Medicines 2 2
10 Medicines Affecting the Blood 9 1 10
11 Blood Products and Plasma Substitutes 4 4
12 Cardiovascular Medicines 25 3 12 34
13 Dermatological Medicines 13 2 1 3 13
14 Diagnostic Agents 5 5
15 Disinfectants and Antiseptics 8 2 6
16 Diuretics 5 1 4
17 Gastrointestinal Medicines 13 3 16
18 Hormones, Other Endocrine Medicines
26
and Contraceptives 1 2 27
19 Immunologicals 22 4 26
20 Muscle Relaxants (Peripherally Acting)
4
and Cholinerase Inhibitors 1 5
21 Ophthalmological, Ear, Nose and
22
Throat Preparations 6 1 29
22 Oxytocics and Antioxytocics 5 1 2 6
23 Peritoneal Dialysis Solution 1 1
24 Psychotherapeutic Medicines 15 1 2 16
25 Medicines Acting on the Respiratory
8 1
Tract 1 6
26 Solution Correcting Water, Electrolyte
8
and Acid Base Disturbances 8

3
27 Vitamins and Minerals 8 2 3 9
28 Specific Medicines for Neonatal care 0 2 2
29 Medicines for Diseases of Joint 0 3***
M* = Main list
C** = Complimentary list
***allopurinol, colchicine and methotrexate shifted to new category 29

4
Table showing addition, deletion and medicines whose dose have been changed or shifted to main or complimentary list
Additio Mol
Li n/Deleti ecul Dosage Streng
S.No. Group Name of Drug Dosage form st on e form th Reason

Sevoflurane inhalation C Addition 1 1 1 Recovery is fast


1 Anesthetics

Increased potency and


Midazolam injection, 1 mg/ml, 5 mg/ml M Addition 1 1 2 faster recovery

Ibuprofen oral liquid, 200 mg/5ml M Addition 0 1 1 For Paedriatic patients


300 mg is Low
therapeutic dose for
analgesic and antipyretic
Medicines for Aspirin tablet, 500 mg C Change 0 0 1 action
2 pain and
Codeine Good for severe pain and
palliative care
phosphate tablet, 30 mg M Addition 1 1 1 post operative pain

Paracetamol oral drop 100 mg/ml M Change 0 1 1 For Paedriatic patients


50 to 100 times stronger
Fentanyl injection, 50mcg/ml M Addition 1 1 1 analgesic than morphine
Common Cost effective
Cetrizine tablet 10 mg
Antihistaminics M Addition 1 1 1 drug
and Medicine Chlopheniramin
3 tablet 4 mg
used in e maleate M Deletion 1 1 1 Problem with availability
Anaphylaxis Effective for Paedriatic
Fexofenadine oral liquid 30mg/5ml
C Addition 1 1 1 patients
Antidotes and
Other
4
Substances Used
in Poisonings Ethyl alcohol injection M Deletion 1 1 1 Problem with availability

5
tablet, 400 mg, oral liquid 100 To address Paedriatic
Carbamazepine mg/5ml M Addition 0 1 2 patients
To address Paedriatic
Antiepileptics / Valporic acid oral liquid 200 mg/5 ml M Addition 0 1 1 patients
5
Anticonvulsants
Paraldehyde injection, 500 mg/ml C Deletion 1 1 1 Problem with availability

tablet 60 mg, injection, 200 To address Paedriatic


Phenobarbital mg/ml M Addition 0 2 2 patients

6.1 Anthelmintics
Niclosamide tablet, 500 mg M Shift 0 0 0

dt 250 mg, powder for oral To address Paedriatic


Amoxicillin liquid M Addition 0 2 2 patients

capsule 250mg, dry syrup To increase microbial


6.2 Antibacterials
Cephalexin 125/250/5 ml M Addition 1 2 3 coverage

500 mg, dry powder for First line treatment for


Vancomycin injection C Addition 1 1 1 complicated infections
To address National TB
Linezolid tablet, 300 mg M Addition 1 1 1 Programme
Streptomycin inj. 75 g M Deletion 0 1 1 Problem with availability

6
Isoniazid +
rifampicin + To address National TB
pyrazinamide tablet, injection M Change 0 0 1 Programme
Isoniazid + To address National TB
rifampicin tablet, injection M Change 0 0 1 Programme
To address National TB
Bedaquiline tablet, 100 mg M Addition 1 1 1 Programme
To address National TB
Pyrazinamide sachet M Change 0 0 1 Programme
Isoniazid +
rifampicin+ Not in WHO model list of
pyrizinamide tablet 30+60+150 M Deletion 1 1 1 essential drugs

For the treatment of oral


Clotrimazole mouth paint 1% w/v M Addition 0 1 1 infections

Antifungal
6.3
Medicines

oral liquid 50 mg/5ml, 100000 For the treatment of oral


Nystatin iu/ml, mouth paint M Addition 0 2 2 infections

tablet, 30,45,75 mg, oral To address the national


Antiviral
6.4 Oseltamivir powder 6mg/ml M Addition 1 2 4 programme
Medicines

Acyclovir tablet, 400/800 mg M Addition 0 0 2 Low therapeutic dosage

Didanosine capsule 250/400 mg M Deletion 1 1 2 Phased out

7
To address National
Nevirapine capsule 50 mg M Addition 0 1 1 Programme
To address National
Ritonavir tablet 100 mg M Addition 1 1 1 Programme
Abacavir/lamiv To address National
udine tablet 60/30 mg M Addition 1 1 1 Programme
Emtricitabine/t To address National
enofovir tablet, 200/300 mg M Addition 1 1 1 Programme
Lopinavir/riton To address National
avir tablet, 100/25 mg M Addition 1 1 1 Programme
Zidovudine/lam To address National
ivudine tablet, 60/30 mg M Addition 1 1 1 Programme
Zidovudine/lam
ivudine/nevirap To address National
ine tablet, 60/30/50 M Addition 1 1 1 Programme

Entecavir To increase antiviral


tablet, 0.5, 1 mg M Addition 1 1 2 coverage

Sofosbuvir To increase antiviral


tablet, 400mg M Addition 1 1 1 coverage

Diloxanide
Antiprotozoal tablet, 500 mg M Deletion 1 1 1 Problem with availability
6.5
Medicines
Paromomycin
injection, 750 mg M Deletion 1 1 1 Problem with availability
Antimigraine
7 Ergometrine
Medicines tablet 1 mg M Deletion 1 1 1 Not preferred drugs

Etoposide
tablet, 100 mg M Addition 0 1 1 Oral form addition
Antineoplastic,
8 Immunosuppress Methotrexate
ives tablet, 5,10 mg M Addition 0 0 2 Dosage form addition

Procarbazine
tablet, 50 mg M Addition 1 1 1 Increase coverage

8
Bleomycin
powder for injection, 15 mg M Shift 0 0 0
Medicines
10 Affecting the Enoxaparin INR monitoring not
Blood injection 30,60,80 mg M Addition 1 1 3 needed as heparin

Atenolol Other safer alternative


tablet, 50 mg, 100 M Deletion 1 1 2 available

Aspirin Addition of approved


tablet 150, 300 mg M Addition 0 1 2 doses

Metoprolol
tablet, 12.5/25/50 mg M Addition 1 1 3 Safter than atenolol

Metoprolol
12.5/25/50 mg M Addition 1 1 3 Safter than atenolol

Atenolol Not preferred choice of


Cardiovascular tablet 25,50,100 mg M Deletion 1 1 3 drug
12
Medicines

Amiodarone
tablet 100 mg, injection
50mg/ml M Addition 1 2 2 Preferred choice

Hydralazine For hypertensive


injection, 20 mg M Addition 1 1 1 emergencies

Amlodipine Common Cost effective


tablet, 2 .5, 5 mg M Addition 1 1 2 drug

Losartan Common Cost effective


tablet, 25, 50 mg M Addition 1 1 2 drug

Atenolol Common Cost effective


tablet 25 mg M Addition 0 0 1 drug

9
For hypertensive
Labetalol emergencies in
injection, 5 mg/ml M Addition 1 1 1 pregnancies

Enalapril
tablet, 5,10,20 mg M Deletion 1 1 3 Replaced with ramipril

Ramipril
tablet, 2.5, 5 mg M Addition 1 1 2 Replaced for enalapril

Frusemide
tablet, 20/40 mg, injection
10mg/ml M Addition 1 2 3 Preferred choice

Spirolactone
tablet 25 mg M Addition 1 1 1 Preferred choice

Clopidogrel Common Cost effective


tablet, 75 mg M Addition 1 1 1 drug

Fenofibirate Common Cost effective


tablet 80, 160 mg M Addition 1 1 2 drug
Selenium Frequently causes
sulfide suspension 2% C Deletion 1 1 1 irritations

Fluconazole Common Cost effective


capsule, 150 mg M Addition 1 1 1 drug
13
Dermatological
Mupirocin Increase coverage due to
Medicines cream/oint 2% M Addition 1 1 1 broad spectrum coverage

Salisylic acid Common Cost effective


cream 10,20,40% M Addition 1 1 3 drug
Not preferred choice of
Coal tar
solution 5% M Deletion 1 1 1 drug
Lindane lotion 1% M Deletion 1 1 1 Phased out
Disinfectants Permethrin 5 % lotion M Shift 0 0 0
15
and Antiseptics Common Cost effective
Povidine iodine
solution 10% M Addition 0 0 1 drug

10
Formaldehyde
solution 3% M Deletion 1 1 1 Phased out

Cetrimide Not preferred choice of


solution 20% M Deletion 1 1 1 drug

16 Diuretics Triamterene Not preferred choice of


tablet, 50 mg M Deletion 1 1 1 drug

Granisetron Antiemetics for cancer


tablet, 1, 2 mg M Addition 1 1 2 patients

Gastrointestinal Isobgol husk


17 oral powder M Addition 1 1 1 Common laxatives
Medicines
Drotaverine
hydrochloride Common Cost effective
tablet 40/80 mg C Addition 1 1 2 drug

Ethinylestradiol
+levonorgestrel
20/1000 mcg* M Addition 0 0 1 Low therapeutic dosage
Silicon ring
pessaries M Addition 1 1 1 Preferred choice
Hormones, Other Gibenclamide Not preferred choice of
Endocrine tablet, 2.5, 5 mg M Deletion 1 1 2 drug
18
Medicines and Common Cost effective
Contraceptives Glicazide
tablet, 40, 80 mg M Addition 1 1 2 drug

Metformin
tablet 850 mg M Addition 0 0 1 Increase the range

Levothyroxine
tablet, 25,50,75 mcg M Addition 0 0 3 Increase the range
Diphtheria Request from health
19 Immunologicals
antitoxin M Addition 1 1 1 services

11
Rotavirus Request from health
M Addition 1 1 1 services

Pneumococcal Request from health


M Addition 1 1 1 services
To cover the national
Hpv M Addition 1 1 1 programme
Muscle
Relaxants
(Peripherally
20
Acting) and
Cholinerase powder for injection,
Inhibitors Atracurium 25,50,100 mg C Addition 1 1 3 To increase the range

Fluconazole eye drop, 0.3 % M Addition 1 1 1 To cover antifungal range

Propacaine eye drop, 0.5 % M Addition 1 1 1 Not in Formal list

Clotrimazole ear drops 1%


Ophthalmologica M Addition 1 1 1 To cover antifungal range

21
l, Ear, Nose and
Ofloxacin eye drop 0.3 % To incease antibacterial
Throat C Addition 1 1 1 range
Preparations
Ciprofloxacin drop 0.3% To increase antibacterial
M Addition 1 1 1 range

Betamethasone ear drops 0.5 %


M Addition 1 1 1 Common choice

Benzocaine solution 20% Local anesthetics for


M Addition 1 1 1 Dental not in formal list

Isoxsuprine
injection 5mg/ml Safer alternative
Oxytocics and hydrochloride
22 M Deletion 1 1 1 available
Antioxytocics
Nefedipine capsule 10 mg
M Addition 1 1 1 Safer in pregnancy

12
Terbutaline injection, 0.5 mg/ml
M Addition 1 1 1 Common choice

Chlorpromazine injection, 25mg/ml


M Deletion 1 1 Not easily available

Olanzapine tablet, 2.5,5,10 mg


Psychotherapeuti M Addition 1 1 1 Relatively safer
24
c Medicines Safer alternative
Alprazolam tablet 0.25, 0.5, 1 mg
M Deletion 1 1 3 available

Lorazepam tablet, 1,2 mg Longer duration of action


M Addition 1 1 2 than Diazepam
Chromoglicic
acid inhalation, 5 mg, 20 mg M Deletion 1 1 2 Not common
Medicines
Safer alternative
Acting on the
25 Theophylline tablet, 300 mg C Deletion 1 1 1 available
Respiratory
Tract
Sodiumbicarbo
nate injection, 7.5% solution M Change 0 0 0

Ascorbic acid tablet, 500 mg M Change 0 0 0


Vitamin B
complex M Deletion 1 1 1 Not essential

Vitamins and Thiamine tablet, 100 mg M Addition 1 1 1 Single vitamin


27
Minerals
Cynocobalamin injection, 30 mcg/ml M Addition 1 1 1 Single vitamin
retinol (as palmitate)+dl-alpha-
tocopherol or tocopheryl
Retinol + DL- acetate, soft gel capsule, 200
alpha- 000 iu+ 40 iu, 100 000 iu+ 20 Vitamin E not in
tocopherol iu, 50 000 iu+ 20 iu M Deletion 1 1 1 therapeutic dose

13
Calcium tablet 500 mg M Addition 1 1 1 Single mineral

Caffine citrate injection, 20 mg/ml M Addition 1 1 1 For Paedriatic patients


Specific
28 Medicines for Chlorohexidine solution/ gel 7.1 % M Addition 1 1 1 For Paedriatic patients
Neonatal care Allopurinol 300 mg Addition 0 0 1 Increase the range
Medicines for
29
Diseases of Joint
total 86 106 158

14
National List of Essential Medicines, 2016
Main List Complementary List Dosage Form
1. Anaesthetics
1.1 General Anaesthetics and Oxygen
Halothane inhalation
Isoflurane inhalation
Ketamine injection, 50 mg/ml (as hydrochloride) in 10-ml
vial
Nitrous oxide inhalation
Oxygen inhalation (medicinal gas)
Thiopental powder for injection, 0.5g, 1.0g (sodium salt) in
ampoule
Propofol injection, 10mg/ml in 20-ml ampoule
Sevoflurane inhalation
1.2 Local Anaesthetics
Bupivacaine injection, 0.25%, 0.5% (hydrochloride) in vial
Lidocaine (lignocaine) injection, 1%, 2% (hydrochloride) in vial;
injection for spinal anaesthesia, 5%
(hydrochloride) in 2-ml ampoule to be mixed
with 7.5% glucose solution
Lidocaine (lignocaine) + epinephrine (adrenaline) injection, lignocaine 2% (hydrochloride) +
epinephrine 1:200 000, in vial
Ephedrine* injection, 30 mg (hydrochloride)/ml in 1-ml
ampoule
*For use in spinal anaesthesia during delivery, to prevent hypotension
1.3 Preoperative Medication and Sedation for Short-term Procedures
Atropine injection, 1 mg (sulfate) in 1-ml ampoule
Diazepam injection, 5mg/ml in 2-ml ampoule
Midazolam injection, 1mg/ml, 5mg/ml with/out preservative
Morphine injection, 10 mg (sulfate or hydrochloride) in 1-
ml ampoule
2 Medicines for Pain and Palliative Care
2.1. Non-opioid Analgesics & NSAIMs
Ibuprofen tablet, 200 mg, 400 mg, Oral liquid, 100 mg/5ml
Paracetamol tablet, 500mg; injection, 150 mg/ml in 2-ml
ampoule, 10 mg/ml in 100 ml bottle; suspension,
125 mg/5ml
Aspirin tablet, 500 mg
Diclofenac Sodium tablet, 50 mg, injection 25 mg/ml
2.2. Opioid Analgesics
Codeine tablet, 30 mg (as phosphate)
Fentanyl injection, 50mcg/ml
Morphine injection, 10 mg (sulfate or hydrochloride) in 1-
ml ampoule; tablet, 10 mg; prolonged release
tablet, 10 mg, 30 mg, 60 mg (sulfate); oral liquid
10 mg/5ml (sulfate)
Pethidine injection, 50 mg (hydrochloride) in 1-ml
ampoule
3 Antihistaminics and Medicines Used in Anaphylaxis
Cetirizine tablet 10 mg,
Dexamethasone injection, 4 mg dexamethasone phosphate (as
disodium salt) in 1-ml ampoule
Epinephrine (adrenaline) injection, 1mg (as hydrochloride or acid tartrate)
in 1-ml ampoule
Hydrocortisone powder for injection, 100 mg (as sodium
succinate) in vial
Pheniramine tablet, 25, 50 mg, injection, 22.75 mg (maleate)
/ml
Prednisolone tablet, 5mg
Fexofenadine oral Solution, 30mg/5 ml
4 Antidotes and Other Substances Used in Poisonings
4.1 Non-Specific
Charcoal, activated powder; oral liquid (sorbitol-base slurry)
4.2 Specific
Atropine injection, 1 mg (sulfate) in ampoule; powder for
injection 50 mg (sulfate) in vial
Dimercaprol injection in oil, 50 mg/ml in 2-ml ampoule
Naloxone injection, 400 mcg (hydrochloride) in 1-ml
ampoule
Pralidoxime injection, 500 mg or 1 g (mesilate, chloride or
iodide) in ampoule
Acetylcysteine injection, 200 mg/ml in 10-ml ampoule
Calcium gluconate injection, 100 mg/ml in 10-ml ampoule
Deferoxamine powder for injection, 500 mg (mesilate) in vial
Methylthioninium chloride injection, 10 mg/ml in 10-ml ampoule
(Methylene blue)
Potassium ferric hexacyano- powder for oral administration
ferrate (II).2H2O (Prussian
blue)
Sodium calcium edetate injection, 200 mg/ml in 5 ml ampoule
Sodium nitrite injection, 30 mg/ml in 10-ml ampoule
5. Antiepileptics / Anticonvulsants
Carbamazepine tablet, 100, 200 mg, 400 mg, Oral liquid
100mg/5ml
Diazepam injection, 5mg/ml in 2- ml ampoule (intravenous
or rectal)
Magnesium sulfate* injection, 500 mg/ml in 2-ml ampoule.
* For use in eclampsia and severe pre-eclampsia and not for other convulsant disorders.
Phenobarbital tablet, 15 mg, 30 mg, injection 200mg/ml
Phenytoin capsule or tablet, 25 mg, 50 mg, 100 mg (sodium
salt); injection, 50 mg /ml (sodium salt) in 5-ml
vial
Valproic acid tablet (enteric coated), 200 mg (sodium salt),
Oral liquid 200mg/5ml
6 Anti-infective Medicines
6.1 Anthelmintics
6.1.1 Intestinal Anthelmintics
Albendazole tablet (chewable), 400 mg
Niclosamide tablet (chewable), 500 mg
Praziquantel tablet, 150 mg, 600 mg
6.1.2 Antifilarials
Diethylcarbamazine tablet, 50 mg, 100 mg (dihydrogen citrate)
6.2 Antibacterials
6.2.1 Beta-lactam medicines
Amoxicillin capsule or tablet, 250 mg, 500 mg (as trihydrate);
dispersible tablet 125 mg (as trihydrate), powder
for oral liquid, 125 mg/1ml
Ampicillin powder for injection, 500 mg (sodium salt)
Benzathine benzylpenicillin powder for injection, 600 000 IU, 1200 000 IU,
2400 000 IU in vial
Benzylpenicillin (Penicillin G) powder for injection, 300 mg (0.5 million IU),
600 mg (1 million IU) (as sodium or potassium
salt) in vial
Cephalexin Capsule 250 mg (as monohydrate), Oral liquid
125/5 ml, 250/5 ml (anhydrous)
Cefixime tablet, 200,400* mg
*only listed for single-dose treatment of uncomplicated ano-genital gonorrhoea
Cloxacillin capsule, 250 mg, 500 mg; powder for oral liquid,
125 mg / 5ml; powder for injection, 500 mg (as
sodium salt) in vial
Phenoxymethylpenicillin (Penicillin V) tablet, 250 mg (as potassium salt); powder for
oral liquid, 250 mg/5 ml (as potassium salt)
Procaine benzylpenicillin powder for injection, 300,000 IU in vial
Cefazolin* powder for injection, 1g (as sodium salt) in vial
*For surgical prophylaxis
Ceftriaxone powder for injection, 250 mg (as sodium salt) in
vial
6.2.2 Other Antibacterials
Azithromycin capsule or tablet 250 mg, 500 mg; oral liquid,
200 mg /5ml.
Chloramphenicol capsule, 250 mg, 500 mg; oral liquid, 125 mg /
5ml (as palmitate); powder for injection, 1g (as
sodium succinate) in vial
Ciprofloxacin tablet, 250 mg, 500 mg (as hydrochloride)
Doxycycline capsule, 100 mg (as hydrochloride)
Gentamicin injection, 10 mg, 40 mg / ml (as sulfate) in 2-ml
vial
Metronidazole tablet, 200 mg, 400 mg; injection, 500 mg in
100-ml bottle; oral liquid, 100 mg, 200 mg (as
benzoate) / 5ml
Nitrofurantoin tablet, 100 mg
Sulfamethoxazole+Trimethoprim dispersible tablet, 100mg+20 mg, 200 mg+ 40
mg; tablet 400 mg + 80 mg, 800 mg + 160 mg;
oral liquid, 200mg + 40mg /5ml
Erythromycin tablet, 250 mg (stearate); oral liquid, 250 mg /
5ml (stearate)
Nalidixic acid tablet, 250 mg, 500 mg
Tetracycline capsule 250 mg, 500 mg (as hydrochloride)
Vancomycin powder for inj. 250 mg (as hydrochloride) in vail
6.2.3 Antileprosy Medicines
Clofazimine capsule, 50 mg, 100 mg
Dapsone tablet, 50 mg, 100 mg
Rifampicin capsule or tablet 150 mg, 300 mg
(For the treatment of leprosy, combination therapy is essential to prevent the emergence of drug
resistance)
6.2.4 Antitubercular Medicines
Ethambutol tablet, 100 mg, 400 mg, 600 mg (hydrochloride)
Ethambutol + Isoniazid tablet, 400mg + 150mg
Ethambutol + Rifampicin +Isoniazid tablet, 275 mg + 150 mg+ 75 mg
Ethambutol + Rifampicin +Isoniazid+ Pyrazinamide tablet, 275 mg+150 mg+ 75 mg + 400 mg
Isoniazid tablet, 50mg, 100 mg, 300 mg
Isoniazid + Rifampicin tablet, 60 mg+60 mg, 50 mg+75mg, 75 mg +
150mg
Isoniazid + Rifampicin + Pyrazinamide tablet, 30 mg+ 60 mg+150 mg, 50 mg+75
mg+150 mg
Rifampicin capsule or tablet, 150mg, 300mg, 450 mg
Streptomycin powder for injection, 1 g (as sulfate) in vial
Complementary list: Second-line medicines for the treatment of multi-drug resistant tuberculosis (MDR-
TB) – to be made available only in specialised centres adhering to standard treatment protocol.
Amoxicillin + Clavulanic tablet, 500 mg + 125 mg, 875 mg+125 mg
acid
Bedaquiline tablet, 100mg
Capreomycin powder for injection, 1 g in vial
Clofazimine capsule, 100 mg
Cycloserine capsule, 250 mg
Ethionamide tablet, 125, 250 mg
Kanamycin powder/solution for injection 1 g in vial/
ampoule
Levofloxacin* tablet, 250 mg, 500 mg
Linezolid tablet 300 mg
Moxifloxacin* tablet, 400 mg
Ofloxacin* tablet, 200 mg
*To be decided based on availability and programme considerations.
P-aminosalicylic acid (PAS) granules, 4 g, 9.2 g in sachet; tablet 500 mg
Pyrazinamide tablet, 150 mg, 400 mg, 500 mg
6.3 Antifungal Medicines
Clotrimazole cream, 1%; pessary 100 mg, mounth paint
1%w/v
Fluconazole capsule or tablet, 150 mg
Nystatin oral liquid 50 mg/5 ml, 100000IU/ml mouth
paint
6.4 Antiviral Medicines
6.4.1 Antiherpes Medicines
Aciclovir powder for injection 250 mg (as sodium salt) in
vials; tablet 200/400/800 mg
6.4.2 Antiretrovirals
6.4.2.1 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors
Abacavir (ABC) tablet, 300 mg (as sulfate); oral liquid, 100 mg
(as sulfate)/5ml
Lamivudine (3TC) tablet, 150 mg; oral liquid 50 mg/5ml
Stavudine (d4T) capsule, 15 mg, 20 mg, 30 mg; powder for oral
liquid, 5 mg/5ml
Tenofovir disoproxil fumarate (TDF) tablet, 300 mg (equivalent to 245 mg tenofovir
disoproxil)
Zidovudine (ZDV or AZT) capsule, 100 mg; tablet 300 mg; oral liquid 50
mg/ 5ml
6.4.2.2 Non-nucleoside Reverse Transcriptase Inhibitors
Efavirenz (EFV or EFZ) capsule, 200 mg; tablet, 600 mg
Nevirapine (NVP) tablet, 200 mg; oral liquid, 50 mg/5ml, 50 MG
6.4.2.3 Protease Inhibitors
Indinavir (IDV) capsule, 400 mg (as sulfate)
Lopinavir + Ritonavir (LPV/r) capsule 200 mg + 50 mg
Nelfinavir (NFV) tablet, 250 mg (as mesilate)
Ritonavir tablet100 mg
Saquinavir (SQV) +Ritonavir oral dosage form, 1g+100 mg
6.4.2.4 Fixed-dose Combination
Abacavir + Lamivudine tablet, 60mg + 30 mg
Emtricitabine + Tenofovir tablet, 200mg + 300 mg
Lamivudine + Stavudine tablet, 150 mg + 30 mg
Lopinavir + Ritonavir tablet, 100 mg + 25 mg
Stavudine + Lamivudine + Nevirapine tablet, 30 mg + 150 mg + 200 mg
Zidovudine + Lamivudine tablet, 60 mg + 30 mg, 300 mg + 150 mg
Zidovudine + Lamivudine + Nevirapine tablet, 60 mg + 30 mg + 50 mg, 300 mg + 150
mg + 200 mg
6.4.3 Other antiviral
Entecavir tablet 0.5, 1 mg
Oseltamivir Capsule, 30/45/75 mg as phosphate, Oral powder
6 mg/ml
Sofosbuvir tablet 400 mg
6.5 Antiprotozoal Medicines
6.5.1 Antiamoebic and Antigiardiasis Medicines
Metronidazole tablet, 200mg, 400mg; oral liquid, 200 mg (as
benzoate) / 5 ml.
Tinidazole tablet, 500mg
6.5.2 Antileishmaniasis Medicines
Miltefosine capsule, 50 mg
Amphotericin B powder for injection, 50 mg in vial (as
deoxycholate or liposomal)
Sodium stibogluconate injection, 100mg/ml
6.5.3 Antimalarial Medicines
Artemether* oily injection, 80 mg/ml in 1-ml ampoule.
* For use in the management of severe malaria.
Artemether+lumefantrine* tablet, 20 mg+ 120 mg
* Not recommended in the first trimester of pregnancy or in children below 5 kg.
Artesunate injection, ampoules, containing 60 mg anhydrous
artesunic acid with a separate ampoule of 5%
sodium bicarbonate solution; tablet 50 mg
(To be used in combination with Sulfadoxine + Pyrimethamine.)
Chloroquine tablet, 150 mg base (as phosphate or sulfate);
oral liquid, 50 mg / 5ml (as phosphate or sulfate);
injection, 40mg /ml in 5- ml ampoule (as
phosphate, sulfate or hydrochloride)
Primaquine tablet, 7.5 mg, 15 mg (as diphosphate)
Sulfadoxine + Pyrimethamine tablet, 500 mg + 25 mg
(To be used only in combination with Artesunate.)
Quinine tablet, 300 mg (as bisulfate or sulfate); injection,
300 mg (as dihydrochloride)/ ml in 2-ml
ampoule.
7 Antimigraine Medicines
7.1 For Treatment of Acute Attack
Paracetamol tablet, 500 mg
7.2 For Prophylaxis
Propranolol tablet 20 mg, 40 mg (hydrochloride)
8 Antineoplastic, Immunosuppressives and Medicines Used in Palliative Care
8.1 Immunosuppressive Medicines
Cyclosporin capsule 25 mg
8.2 Cytotoxic Medicines
Calcium folinate (Calcium leucovorin) tablet, 15 mg
Chlorambucil tablet, 2 mg, 5 mg
Cisplatin powder for injection, 10 mg, 50 mg in vial.
Cyclophosphamide tablet, 25 mg; powder for injection, 200 mg, 500
mg, 1 g in vial
Cytarabine injection 100 mg, 500 mg in vial
Dacarbazine powder for injection, 100 mg in vial
Dactinomycin powder for injection, 500 mcg in vial
Daunorubicin powder for injection 20 mg (as hydrochloride) in
vial
Doxorubicin powder for injection, 10 mg, 50 mg in vial
Epirubicin injection, 10 mg, 50 mg (hydrochloride) in vial
Etoposide tablet, 100 mg, injection 20 mg/ml in 5-ml
ampoule
Fluorouracil injection 50 mg/ml in 5-ml, 10-ml ampoule
Hydroxy urea capsule 500 mg
Ifosfamide + Mesna injection, 1g + 200 mg, in vial
Lomustine capsule, 40 mg
Melphalan tablet, 2 mg, 5 mg; powder for injection, 50mg in
vial
Mercaptopurine tablet, 50 mg
Methotrexate tablet, 2.5/5/10 mg (as sodium salt); powder for
injection 15 mg, 50 mg (as sodium salt) in vial
Mitomycin powder for injection, 2mg, 10mg, 20mg in vial
Mitoxantrone injection, 2 mg/ml in 10ml ampoule
Procarbazine capsule 50 mg (as hydrochloride)
Vinblastine powder for injection 10 mg (sulfate) in vial
Vincristine powder for injection, 1 mg (sulfate) in vial
Bleomycin powder for injection, 15mg (as sulfate) in vial
Carboplatin injection 150 mg, 450 mg in vial
8.3 Hormones and Antihormones
Hydrocortisone powder for injection, 100 mg (as sodium
succinate) in vial
Tamoxifen tablet, 20 mg (as citrate)
Bicalitumide tablet or capsule 50 mg
Dexamethasone Dexamethasone phosphate 4 mg /ml (as sodium
salt) in 2-ml ampoule
Prednisolone tablet, 5 mg, 10 mg, 20 mg
8.4 Miscellaneous
Granulocyte Colony Stimulating Factor (GCSF) injection, 30 million unit in vial
Interferon injection, 5 million units/ml in vial
L-Asparaginase injection, 5 000 IU, 10 000 IU in vial
Ondansetron injection, 2 mg/ml (as hydrochloride) in 2-ml, 4-
ml vial; tablet 2mg, 4mg (as hydrochloride)
9 Antiparkinsonism Medicines
Levodopa + Carbidopa tablet, 100 mg + 10 mg, 250 mg + 25 mg
Trihexyphenidyl (benzhexol) tablet, 2 mg (hydrochloride)
10 Medicines Affecting the Blood
10.1 Antianaemia Medicines
Ferrous sulfate* tablet, equivalent to 60 mg iron; oral liquid,
equivalent to 25 mg iron/ ml
Ferrous sulfate*+Folic acid tablet, equivalent to 60 mg Iron+ 400 mcg Folic
acid, oral drop.
*Ferrous fumarate may be used
Folic acid tablet, 5mg
Iron Dextran injection, equivalent to 50 mg iron/ml in 2-ml
ampoule
10.2 Medicines Affecting Coagulation
Enoxaparin injection 30mg/0.3ml, 60mg/0.6ml, 80mg/0.8ml
Heparin sodium injection, 1000 IU/ml, 5000 IU/ml,20000IU/ml
in 1-ml ampoule
Phytomenadione injection, 10mg /ml in 5-ml ampoule; tablet 10
mg
Protamine sulfate injection, 10mg/ml in 5-ml ampoule
Warfarin tablet, 1 mg, 2 mg, 5 mg (sodium salt)
Acenocoumarol tablet, 1mg
11 Blood Products and Plasma Substitutes
11.1 Plasma Substitutes
Albumin, human injectable solution, 20 or 25%
Polygeline injectable solution, 3.5%
11.2 Plasma Fractions For Specific Use
Factor VIII Concentrate dried concentrate
Factor IX complex dried concentrate
12 Cardiovascular Medicines
12.1 Antianginal Medicines
Glyceryl trinitrate tablet (sublingual), 500 mcg
Isosorbide dinitrate tablet (sublingual), 5 mg, 10 mg
Metoprolol tablet, 12.5,25,50 mg
Verapamil tablet, 40 mg, 80 mg (hydrochloride); injection,
2.5 mg / ml in 2-ml ampoule
12.2 Antiarrhythmic Medicines
Amiodarone tablet 100 mg, injection 50mg/ml
Digoxin tablet, 62.5 mcg, 250 mcg; oral liquid, 50 mcg /
ml; injection, 250 mcg / ml in 2-ml ampoule
Epinephrine (Adrenaline) 100 mcg/ml (as acid tartrate or hydrochloride) in
10 ml ampoule
Isoprenaline injection, 1 mg (hydrochloride)/ml in vial
Lidocaine (Lignocaine preservative free) injection 2 % (hydrochloride) in vial
Metoprolol tablet, 12.5,25,50 mg
Disopyramide capsule, 100 mg, 150 mg
Procainamide tablet, 250 mg (hydro- chloride); injection, 100
mg /ml in 10-ml ampoule
12.3 Antihypertensive Medicines
Amlodipine tablet 2.5, 5 mg
Atenolol tablet 25, 50,100 mg
Enalapril tablet, 5 mg, 10 mg, 20 mg
Hydralazine injection 20 mg
Hydrochlorothiazide tablet, 25 mg, 50 mg
Labetalol injection 5 mg/ml 20 ml
Losartan tablet, 25, 50mg
Methyldopa* tablet, 250 mg
* Listed for the use in the management of pregnanacy induced hypertention only
Nifedipine sustained release tablet, 10 mg, 20 mg
Prazosin sustained release tablet 500 mcg, 1mg (mesilate)
Sodium nitroprusside powder for infusion, 50 mg in ampoule
12.4 Medicines Used in Heart Failure
Digoxin tablet, 62.5 mcg, 250 mcg; oral liquid, 50 mcg /
ml; injection, 250 mcg / ml in 2-ml ampoule
Furosemide injection, 10 mg/ml in 2ml ampoule. tablet, 20,
40 mg
Ramipril tablet 2.5, 5 mg
Spironolactone tablet, 25 mg
Dobutamine injection, 12.5 mg/ml (as hydrochloride) in 20-
ml ampoule
Dopamine injection 40mg/ml (hydrochloride) in 5- ml vial
12.5 Antithrombotic Medicines
Aspirin tablet, 50mg, 75 mg, 100mg
Clopidogrel tablet 75 mg
Streptokinase injection 750000 IU, 1500 000 IU in vial
12.6 Lipid Lowering Agent
Atorvastatin tablet, 10 mg, 20 mg (as calcium trihydrate)
Fenofibirate tablet, 80, 160 mg
13 Dermatological Medicines
13.1 Antifungal Medicines
Benzoic acid + Salicylic acid ointment or cream, 6% + 3%
Clotrimazole cream, 1%
Fluconazole capsule 150 mg
13.2 Anti-infective Medicines
Mupirocin 2 % cream/ont
Povidone iodine solution, 5%
Silver sulfadiazine cream, 0.2%
Gentian violet
(Methylrosanilinium
chloride) aqueous solution 1%
13.3 Anti-inflammatory and Antipruritic Medicines
Betamethasone ointment or cream, 0.1% (as valerate)
Calamine lotion lotion, 15%
Hydrocortisone ointment or cream, 1% (acetate)
13.4 Medicines Affecting Skin Differentiation and Proliferation
Benzoyl peroxide cream or lotion, 5%
Salicylic acid cream10, 20, 40%
13.5 Scabicides and Pediculicides
Permethrin lotion 1%, cream 5%
14 Diagnostic Agents
14.1 Ophthalmic Medicines
Fluorescein eye drops, 1%, 2% (sodium salt); injection, 10%,
20% (sodium salt) in 5-ml ampoule
14.2 Radiocontrast Media
Amidotrizoate injection, 140-420 mg iodine/ml (as sodium or
meglumine salt) in 20, 50 ml ampoule
Barium sulfate 100-250% w/v in aqueous suspension
Iohexol injection, 140-350 mg iodine/ml in 10/20 ml
ampoule
Meglumine iotroxate solution, 5-8 g iodine in 100-250 ml
15 Disinfectants and Antiseptics
15.1 Antiseptics
Chlorhexidine solution, 5% (digluconate) for dilution, solution*
or ointment, 4 %
*Only for umbilical cord stump care
Gentian violet (Methylrosanilinium chloride) aqueous solution, 1%
(Powder may be supplied for preparation of solution at the health facility)
Povidone iodine solution, 5%, 10 % w/v
Rectified spirit liquid (90 % v/v)
15.2 Disinfectants
Chlorine based compound powder, (0.1% available chlorine) for solution
Glutaraldehyde solution, 2%
16 Diuretics
Furosemide tablet, 40 mg; injection, 10 mg/ml in 2-ml
ampoule
Hydrochlorothiazide tablet, 25mg, 50 mg
Mannitol injectable solution, 10%, 20%
Spironolactone tablet, 25 mg, 100 mg
17 Gastrointestinal Medicines
17.1 Antacids and Other Anti-ulcer Medicines
Dried aluminium hydroxide gel + Magnesium tablet, 250 mg + 250 mg
hydroxide*
(*Tablet containing Magnesium trisilicate 500 mg may be used.)
Ranitidine tablet, 150 mg, 300 mg (as hydrochloride);
injection 25 mg/ml in 2-ml ampoule
Omeprazole capsule, 20 mg
17.2 Antiemetic Medicines
Granisetron tablet 1, 2 mg
Metoclopramide tablet, 10 mg (hydrochloride); injection, 5 mg
(hydrochloride)/ml in 2-ml ampoule
Promethazine tablet, 25 mg (theoclate); oral liquid, 5 mg
(hydrochloride)/ 5ml;injection, 25 mg
(hydrochloride) / ml in 2-ml ampoule
17.3 Anti-inflammatory Medicines
Sulfasalazine tablet, 500 mg
17.4 Laxatives
Lactulose solution, 3.35 mg / 5ml
Magnesium sulfate powder, 500 g
Bisacodyl tablet, 10 mg
Ispaghula husk oral powder
17.5 Medicines Used in Diarrhoea
17.5.1 Oral Rehydration
Oral rehydration salts* sachet containing: Dextrose, anhydrous 13.5 g,
Sodium chloride 2.6 g, Potassium chloride 1.5 g,
Trisodium citrate dihydrate 2.9g, appropriate
flavour q.s. Dissolved to produce 1 litre,
provides dextrose 75mEq, sodium 75 mEq or
mmol/l, chloride 65 mEq or mmol/l, potasium 20
mEq or mmol/l, citrate 10 mmol/l and osmolarity
245 mOsm/l
* In case of cholera a higher concentration of sodium may be required.
17.5.2 Medicine for Diarrhoea in Children
Zinc sulfate* dispersible tablet, equivalent to Zinc 10 mg, 20
mg (scored)
* In acute diarrhoea, zinc sulfate should be used as an adjunct to oral rehydration salts
Zinc sulfate oral solution, 10 mg/5ml in 50- ml bottle
17.6 Antispasmodic Medicines
Hyoscine butylbromide tablet, 10 mg, 20 mg; injection, 20 mg/ml in 1-ml
ampoule
Drotaverine hydrochloride tablet 40/80 mg

18 Hormones, Other Endocrine Medicines and Contraceptives


18.1 Adrenal Hormones and Synthetic Substitutes
Dexamethasone tablet, 500 mcg; injection, 4 mg/ml
dexamethasone phosphate (as sodium phosphate)
in 1-ml ampoule
Hydrocortisone powder for injection, 100 mg (as sodium
succinate) in vial; tablet, 10 mg, 20 mg
Prednisolone tablet, 5 mg, 10 mg
Fludrocortisone tablet, 100 mcg (acetate)
18.2 Androgens
Testosterone injection, 200 mg in 1-ml ampoule

18.3 Contraceptives
18.3.1 Oral Harmonal Contraceptives
Ethinylestradiol + Levonorgestrel tablet, 30 mcg +150 mcg, 20 mcg +1.0 mg.
Ethinylestradiol + Norethisterone tablet, 35 mcg + 1.0 mg,
Levonorgestrel tablet, 750 mcg (pack of two), 1.5 mg)
18.3.2 Injectable Hormonal Contraceptive
Medroxyprogesterone acetate depot injection, 150 mg / ml in 1-ml vial
18.3.3 Intrauterine Devices
Copper-containing devices
18.3.4 Barrier Methods
Condoms
18.3.5 Implantable Contraceptives
Hormoal intrauterine device – multiple advantages
Intrauterine device with progestogen
Levonorgestrel-releasing implant two-rod levonorgestrel-releasing implant, each
rod containing 75 mg of levonorgestrel (150 mg
total)
18.3.6 Miscellaneous
Ring pessary
Silicon ring pessary
18.4 Estrogens
Ethinylestradiol tablet, 50 mcg
18.5 Insulins and Other Antidiabetic Agents
Gliclazide tablet 40,80 mg
Insulin (soluble injection, 40 IU / ml in 10- ml vial
Intermediate acting insulin injection, 40 IU / ml in 10- ml vial (as compound
insulin zinc suspension or isophane insulin)
Metformin tablet, 500 mg (hydrochloride), 850 mg
Glipizide tablet, 2.5 mg, 5 mg

18.6 Ovulation Inducers


Clomifene tablet, 50 mg (citrate)
18.7 Progestogens
Norethisterone tablet, 5 mg
Medroxyprogesterone acetate tablet, 5 mg
18.8 Thyroid Hormones and Antithyroid Medicines
Carbimazole tablet, 5 mg
Levothyroxine tablet,25, 50,75,100 mcg (sodium salt)
Lugol's Iodine oral solution (Iodine 5%+Potassium iodide 10%)
18.9 Posterior Pituitary Hormone
Desmopressin injection, 4 mcg/ml; nasal spray 10 mcg /
metered spray
19 Immunologicals
19.1 Diagnostic Agents
Tuberculin, purified protein derivative (PPD) injection
19.2 Sera and Immunoglobulins
Anti-D immunoglobulin (human) injection, 250 mcg in single dose vial
Antirabies hyperimmune serum injection, 1000 IU in 5-ml ampoule
Polyvenum antisnake serum injection in vial
Tetanus antitoxin injection, 1 000 IU/ml, 3000 IU/ml in vial
Tetanus immunoglobulin (human) injection, 500 IU in vial
19.3 Vaccines
19.3.1 For Universal Immunization
BCG vaccine
Diphtheria, Tetanus, Pertussis, Hepatitis B vaccine
Diphtheria, Tetanus, Pertussis, Hepatitis B, vaccine
Haemophilus influenzae type b
Measles vaccine (live attenuated)
Poliomyelitis (oral) vaccine
Tetanus toxoid vaccine
19.3.2 For Specific Groups of Individuals
Diphtheria Antitoxin vaccine
Hepatitis A vaccine
Hepatitis B vaccine
Human papiloma vaccine (HPV) vaccine
Influenza vaccine
Japanese Encephalitis SA 14-14-2 strain live attenuated vaccine
Meningococcal meningitis vaccine
Mumps vaccine
Rubella vaccine
Typhoid vaccine
Yellow fever vaccine vaccine
Rabies vaccine, freeze-dried vaccine
20 Muscle Relaxants (Peripherally Acting) and Cholinesterase Inhibitors
Neostigmine tablet, 15 mg (bromide); injection 500 mcg, 2.5
mg (metilsulfate) in 5-ml ampoule
Pancuronium bromide injection, 2 mg / ml in 2-ml ampoule
Suxamethonium chloride injection, 50mg /ml in 10 vail
Vecuronium bromide powder for injection 10 mg in vial
Atracurium powder for injection, 25,50, 100 mg injection
21 Ophthalmological, Ear, Nose and Throat Preparations
21.1 Ophthalmological Preparations
21.1.1 Anti-infective Agents
Aciclovir ointment, 3%
Fluconazole 0.3% eye drop
Gentamicin solution (eye drops), 0.3% (sulfate)
Chloramphenicol applicap, 1%
Ciprofloxacin eye/ear drops, 0.3% (as hydrochloride); eye
ointment, 0.3%
Ofloxacin eye drop 0.3 %
Tetracycline eye ointment, 1% (hydrochloride)
21.1.2 Anti-inflammatory agents
Prednisolone solution (eye drops), 0.5%
21.1.3 Local Anaesthetics
Lidocaine (Lignocaine) injection, 2%, 4% (topical)
Proparacaine solution (eye drops),0.5%
Tetracaine solution (eye drops), 0.5%
21.1.4 Miotics and antiglaucoma medicines
Acetazolamide tablet, 250 mg
Pilocarpine solution (eye drops), 2%, 4% (hydrochloride)
Timolol solution (eye drops), 0.5 % (maleate)
21.1.5 Mydriatics
Atropine solution (eye drops), 1% (sulfate)
Tropicamide solution (eye drop), 0.5%
21.2 Ear, Nose and Throat Preparations
Betamethasone ear drops/cream0.05 %
Bismuth Iodoform Paraffin solution, 70%
Chloramphenicol ear drops, 5%
Ciprofloxacin 0.3% drops (as hydrocholoride)
Clotrimazole ear drops 1%
Ichthammol + Glycerin, ear drop, 10%+5%
Lidocaine (Lignocaine) topical (viscous), 2%, 4%
Oxymetazoline solution (nasal drops), 0.025%, 0.05%
Sodium bicarbonate + Glycerin ear drops, 1%+5%
21.3 Dental
Benzocaine solution 20%
Chlorhexidine solution, 0.2% (gluconate)
Clove oil oil
Zinc oxide powder
22 Oxytocics and Antioxytocics
22.1 Oxytocics
Methylergometrine injection, 200 mcg (maleate) /ml in ampoule
Oxytocin injection, 5 IU/ml in1-ml ampoule
Mifepristone*+Misoprostol tablet, 200mg+200 mcg
*Combi-pack, containing 1 tablet of mifepristone and 4-tablet of misoprostol. Requires close medical
supervision. Approved for abortion services only in listed sites.
Misoprostol tablet, 200 mcg, vaginal tablet, 25 mcg
22.2 Anti-oxytocics
Nifedipine capsule 10 mg
Terbutaline injection 0.5 mg/ml
23 Peritoneal Dialysis Solution
Intraperitoneal dialysis solution parenteral solution of appropriate composition
24 Psychotherapeutic Medicines
24.1 Medicines Used in Psychotic Disorders
Chlorpromazine tablet, 50 mg, 100 mg (hydrochloride); oral
liquid, 25 mg (hydrochloride) / 5ml;
Fluphenazine injection, 25 mg (decanoate or enantate) in 1-ml
ampoule.
Haloperidol tablet 2 mg, 5 mg; injection, 5 mg in 1-ml
ampoule
Olanzapine tablet 2.5, 5, 10 mg
Resperidone tablet, 1 mg, 2mg
Thioridazine tablet, 10mg, 25mg, 100mg
24.2 Medicines Used in Mood Disorders
24.2.1 Medicines used in depressive disorders
Amitriptyline tablet, 10 mg, 25 mg, 75 mg (hydrochloride)
Fluoxetine capsule or tablet, 20 mg (as hydrochloride)

24.2.2 Medicines Used in Bipolar Disorders


Lithium carbonate capsule or tablet, 300 mg (sustained release)
24.3 Medicines Used in Generalised Anxiety and Sleep Disorders
Chlordiazepoxide tablet, 10 mg, 25 mg
Diazepam tablet 2 mg, 5 mg
Lorazepam tablet, 1, 2 mg
24.4 Medicines Used for Obsessive Compulsive Disorders and Panic Attacks
Clomipramine capsules, 10 mg, 25 mg (hydrochloride)
24.5 Medicines Used in Substance Dependence Programmes
Methadone* concentrate for oral liquid, 5 mg/ml, 10 mg/ml
(hydrochloride), oral liquid, 5 mg/5ml, 10 mg/5
ml, tablet 5 mg
Buprenorphine* sublingual tablet, 200 mcg
*The medicines should only be used within an established support programme.
Disulfiram tablet, 200 mg
25 Medicines Acting on the Respiratory Tract
25.1 Antiasthmatic and Medicines for Chronic Obstructive Pulmonary Disease
Aminophylline injection, 25 mg/ml
Epinephrine (Adrenaline) injection, 1 mg (as hydrochloride or acid tartrate)
in 1-ml ampoule.
Hydrocortisone injection (sodium succinate) 100 mg, 200 mg in
vial; tablet, 10 mg
Ipratropium bromide inhalation, 20 mcg/ dose
Salbutamol tablet, 2 mg, 4 mg (as sulfate); inhalation 100
mcg/dose, rotacap 200 mcg (as sulfate) per dose;
oral liquid, 2mg (as sulfate)/5ml; injection
50mcg /ml in 5-ml ampoule
Beclomethasone inhalation (aerosol), 50mcg (as dipropionate) per
dose
26 Solution Correcting Water, Electrolyte and Acid Base Disturbances
26.1 Oral
Oral rehydration salts sachet containing: Dextrose, anhydrous 13.5 g,
Sodium chloride 2.6 g, Potassium chloride 1.5 g,
Trisodium citrate dihydrate 2.9 g, appropriate
flavour q.s. Dissolved to produce 1 litre,
provides Dextrose 75 mEq, sodium 75 mEq or
mmol/l, chloride 65 mEq or mmol/l, potasium 20
mEq or mmol/l, citrate 10 mmol/l and osmolarity
245 mOsm/l
26.2 Parenteral
Compound solution of Sodium lactate (Ringer's injectable solution
Lactate)
Glucose injectable solution, 5% isotonic, 50% hypertonic
Glucose with Sodium chloride injectable solution, 5% glucose, 0.9% sodium
chloride
Potassium chloride injection, 15% in 20ml ampoule
Sodium chloride injectable solution, 0.9% isotonic
Sodium bi-carbonate injectable solution 7.5 % solution in 10-ml
ampoule
26.3 Miscellaneous
Water for injection 5-ml, 10-ml ampoule
27 Vitamins and Minerals
Ascorbic acid tablet, 500 mg
Calcium gluconate injection, 100 mg / ml in 10-ml ampoule
Cynocomalamin injection 30 mcg/ml
Ergocalciferol capsule or tablet, 1.25 mg (50 000 IU) oral
solution, 250 mcg/ ml) (10000 IU / ml)
Pyridoxine tablet, 25 mg (hydrochloride)
Retinol tablet (sugar coated), 10000 IU; capsule, 20000
IU (as palmitate); oral oily solution, 100 000 IU/
ml in multi-dose dispenser; water miscible
injection, 100 000 IU (as palmitate) in 2-ml
ampoule
Retinol +DL-alpha-tocopherol Retinol (as palmitate)+DL-alpha-tocopherol or
tocopheryl acetate, soft gel capsule, 200 000 IU+
40 IU, 100 000 IU+ 20 IU, 50 000 IU+ 20 IU
Riboflavin tablet, 5 mg
Thiamine tablet, 100 mg (as hydrochloride)
28 Specific Medicines for Neonatal Care
28.1 Medicines administered to the neonate
Caffine citrate Injection, 20mg/ml (equivalent to 10 mg caffine
base/ml); Oral liquid: 20 mg/ml (equivalent to 10
mg caffine base/ml)
Chlorhexidine Solution or gel: 7.1% (digluconate) delivering
4% chlorhexidine (for umbilical cord care)
29 Medicines for Diseases of Joints
29.1. Medicines Used to Treat Gout
Allopurinol tablet, 100 mg, 300 mg
Colchicine tablet, 500 mcg
29.2 Disease Modifying Agents Used in Rheumatic Disorders (DMARDs)
Methotrexate tablet, 2.5 mg (as sodium salt)

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