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    Pex 06 04

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    Alvin Phen
    The document summarizes a lab report on the effects of chemical modifiers on heart rate. A group of three students - Noor, Anindya, and Alvin - completed pre-lab quizzes, made predictions, and recorded data on how different chemicals affected heart rate. Pilocarpine, a cholinergic agonist, decreased heart rate as predicted. Atropine, a cholinergic antagonist, increased heart rate. Epinephrine increased heart rate, while digitalis decreased it. In their conclusions, the students accurately described how each chemical modifier affected heart rate.

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    © All Rights Reserved
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    Pex 06 04

    Uploaded by

    Alvin Phen
    76 views5 pages
    The document summarizes a lab report on the effects of chemical modifiers on heart rate. A group of three students - Noor, Anindya, and Alvin - completed pre-lab quizzes, made predictions, and recorded data on how different chemicals affected heart rate. Pilocarpine, a cholinergic agonist, decreased heart rate as predicted. Atropine, a cholinergic antagonist, increased heart rate. Epinephrine increased heart rate, while digitalis decreased it. In their conclusions, the students accurately described how each chemical modifier affected heart rate.

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    PEX-06-04(1)

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    The document summarizes a lab report on the effects of chemical modifiers on heart rate. A group of three students - Noor, Anindya, and Alvin - completed pre-lab quizzes, made predictions, and recorded data on how different chemicals affected heart rate. Pilocarpine, a cholinergic agonist, decreased heart rate as predicted. Atropine, a cholinergic antagonist, increased heart rate. Epinephrine increased heart rate, while digitalis decreased it. In their conclusions, the students accurately described how each chemical modifier affected heart rate.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    76 views5 pages

    Pex 06 04

    Uploaded by

    Alvin Phen
    The document summarizes a lab report on the effects of chemical modifiers on heart rate. A group of three students - Noor, Anindya, and Alvin - completed pre-lab quizzes, made predictions, and recorded data on how different chemicals affected heart rate. Pilocarpine, a cholinergic agonist, decreased heart rate as predicted. Atropine, a cholinergic antagonist, increased heart rate. Epinephrine increased heart rate, while digitalis decreased it. In their conclusions, the students accurately described how each chemical modifier affected heart rate.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 5

    Name: Noor, Anindya, Alvin

    Exercise 6: Cardiovascular Physiology: Activity 4: Examining the Effects of Chemical Modifiers on Heart Rate Lab Report

    Pre-lab Quiz Results


    You scored 100% by answering 4 out of 4 questions correctly.

    1. The parasympathetic nervous system releases __________ to affect heart rate.


    You correctly answered: d. acetylcholine

    2. A cholinergic drug that worked the same as acetylcholine would


    You correctly answered: c. be an agonist and decrease heart rate.

    3. Norepinephrine affects the heart rate by


    You correctly answered: a. increasing the rate of depolarization and increasing the frequency of action potentials.

    4. The __________ receptor binds norepinephrine and epinephrine.


    You correctly answered: b. ß-1 adrenergic

    05/11/20 page 1
    Experiment Results
    Predict Question:
    Predict Question 1: Pilocarpine is a cholinergic drug, an acetylcholine agonist. Predict the effect that pilocarpine will have
    on heart rate.
    Your answer : b. Pilocarpine will decrease heart rate.

    Predict Question 2: Atropine is another cholinergic drug, an acetylcholine antagonist. Predict the effect that atropine will
    have on heart rate.
    Your answer : a. Atropine will increase heart rate.

    Stop & Think Questions:


    Which of the following is true of epinephrine?
    You correctly answered: c. It increases the heart rate and mimics the sympathetic nervous system.

    The final chemical modifier we will look at is digitalis (also known as digoxin and digitoxin and derived from the foxglove
    plant). Individuals with weakened hearts need to allow maximum time for venous return and increased stroke volume and
    would therefore most likely benefit from
    You correctly answered: c. increased force of contraction and decreased heart rate

    Experiment Data:

    Solution Heart Rate


    Atropine 61
    Epinephrine 81
    Pilocarpine 53
    Atropine 67
    Digitalis 50

    05/11/20 page 2
    05/11/20 page 3
    Post-lab Quiz Results
    You scored 100% by answering 4 out of 4 questions correctly.

    1. Pilocarpine decreased the heart rate. Typical of cholinergic agonists, it


    You correctly answered: b. decreased the frequency of action potentials.

    2. The effect of atropine was to


    You correctly answered: c. mimic the sympathetic nervous system.

    3. The modifiers tested that decrease the heart rate were


    You correctly answered: c. digitalis and pilocarpine.

    4. To increase the heart rate, the best choices would be


    You correctly answered: b. epinephrine and atropine.

    05/11/20 page 4
    Review Sheet Results
    1. Describe the effect that pilocarpine had on the heart and why it had this effect. How well did the results compare with
    your prediction?
    Your answer:
    It decreases the HR
    It stimulates the parasympathetic nerves

    2. Atropine is an acetylcholine antagonist. Does atropine inhibit or enhance the effects of acetylcholine? Describe your
    results and how they correlate with how the drug works. How well did the results compare with your prediction?
    Your answer:
    increases HR-stimulates
    increases the frequency of SA
    inhibits vagus nerve (or blocks parasympathetic nerves)

    3. Describe the benefits of administering digitalis.


    Your answer:
    increases the force of contractions
    decrease HR-increase stroke volume
    Slows the sodium pump, which lets more Na+ accumulate heart muscle cells.
    Less Na+ concentration gradient across the membrane
    Na+/Ca+2 antiporters slow down so more Ca+2 remains inside the cardiac cells

    4. Distinguish between cholinergic and adrenergic chemical modifiers. Include examples of each in your discussion.
    Your answer:
    ACh, cholinergic, decreases HR
    Epinephrine & Norepinephrine, adrenergic, increases HR

    Nama: Noor Zain 021911133105


    Anindya Renata 021911133129
    Alvin Phen 021911133114

    05/11/20 page 5

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