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    Chemotheraphy and Its Side Effects

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    ALYSSA MAE RAPER
    The document discusses chemotherapy and its side effects. Chemotherapy is a major treatment for cancer but presents challenges for patients. Side effects from chemotherapy can occur after patients leave treatment facilities. Patients need education on managing side effects at home. Some natural compounds may help reduce chemotherapy side effects when combined with traditional drugs, but unapproved combinations can be dangerous.

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    Chemotheraphy and Its Side Effects

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    ALYSSA MAE RAPER
    25 views2 pages
    The document discusses chemotherapy and its side effects. Chemotherapy is a major treatment for cancer but presents challenges for patients. Side effects from chemotherapy can occur after patients leave treatment facilities. Patients need education on managing side effects at home. Some natural compounds may help reduce chemotherapy side effects when combined with traditional drugs, but unapproved combinations can be dangerous.

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    wiw

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    literature review

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    The document discusses chemotherapy and its side effects. Chemotherapy is a major treatment for cancer but presents challenges for patients. Side effects from chemotherapy can occur after patients leave treatment facilities. Patients need education on managing side effects at home. Some natural compounds may help reduce chemotherapy side effects when combined with traditional drugs, but unapproved combinations can be dangerous.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    25 views2 pages

    Chemotheraphy and Its Side Effects

    Uploaded by

    ALYSSA MAE RAPER
    The document discusses chemotherapy and its side effects. Chemotherapy is a major treatment for cancer but presents challenges for patients. Side effects from chemotherapy can occur after patients leave treatment facilities. Patients need education on managing side effects at home. Some natural compounds may help reduce chemotherapy side effects when combined with traditional drugs, but unapproved combinations can be dangerous.

    Copyright:

    © All Rights Reserved
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    Download as docx, pdf, or txt
    of 2

    Pataclang, Aimee Shannen A.

    Raper, Alyssa Mae A.

    11-delmundo

    CHEMOTHERAPHY AND ITS SIDE EFFECTS

    Cancer is a major health issue. 8.2 million people around the world died from cancer in 2012
    (Ferlay et al. 2015). Chemotherapy is one of the main options for treating cancer. It can be
    prescribed as a standalone treatment, or in parallel or in sequence with radiotherapy or surgery.
    Chemotherapy is mainly delivered by outpatient clinics. These figures show that cancer is a
    major issue, and outpatient chemotherapy is a strategic element in cancer care: its use increases
    and its cost is rising even quicker.

    Cancer and its treatment represent significant challenges for the health care system in America.
    Chemotherapy, in particular, presents a challenge for patients, families, and health care
    professionals. In 1986, approximately 557,000 cancer patients were treated with systemic
    chemotherapy (Devita, 1989). More patients are receiving chemotherapy in outpatient treatment
    facilities than ever before, because it is cost effective and convenient for the patient. Patients are
    treated with a chemotherapy regimen over a period of hours in an outpatient clinic or physician's
    office and are released. If a patient is going to experience side effects from treatment, they will
    most likely experience these effects at home.

    Although some side effects of chemotherapy drugs such as nausea can occur within minutes to
    days after the drugs are given, a potentially life threatening side effect such as myelosuppression
    can occur from one to four weeks. The most dangerous side effects that the patient will usually
    encounter occur after the patient has left the treatment facility. Patients and families need to
    become more familiar with their disease, treatment regimens, and side effects. If they receive
    their treatments in an outpatient clinic or office, they must be provided with specific information
    on how to self-manage treatment side effects. Chemotherapy teaching has focused on educating
    patients about the drugs they are receiving and what side effects they may experience (Dodd &
    Mood, 1981). Oncology nurses need to expand this teaching to include information on self-care
    management of side effects.

    Finally, the combination of natural bioactive compounds with traditional chemotherapeutic drugs
    can potentiate anti-cancer efficacy and reduce side-effects of chemotherapy. In some cases,
    addition of bioactive compounds may overcome the chemo- or radio-resistance of cancer cells.
    These synergistic effects of nutraceutical compounds such as flavonoids, stilbenes, terpenes,
    curcumin, and others have been discussed in a review article by Redondo-Blanco et al. presented
    in this Research Topic. The authors reviewed current knowledge on mechanisms of action of
    these compounds based on studies in colorectal cancer cells, animal models and clinical trials.
    However, the use of non-approved combinations of drugs and unproven remedies may lead to
    severe side-effects and life-threatening toxicities. Uhl et al. present a case report on fatal toxicity
    induced by a combination of dichloroacetate and artemisinin derivative, artesunate. Both drugs
    exert anti-cancer activity in vitro and in vivo, and were trialed in a small number of cancer
    patients; however, a combination of these drugs provoked severe liver and bone marrow toxicity
    in the patient.

    `Refferences:

    Lamé, G., Jouini, O., Stal-Le Cardinal, J., 2016. Outpatient Chemotherapy Planning: a
    Literature Review with Insights from a Case Study. IIE Transactions on Healthcare Systems
    Engineering. doi:10.1080/19488300.2016.1189469

    Nurgali K, Jagoe RT and Abalo R (2018) Editorial: Adverse Effects of Cancer Chemotherapy:
    Anything New to Improve Tolerance and Reduce Sequelae?. Front. Pharmacol. 9:245. doi:
    10.3389/fphar.2018.00245

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