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    Tonicity

    Uploaded by

    amethyst grande
    This document contains solutions to practice problems related to isotonic solutions and electrolyte dissociation. It provides the steps and calculations to determine: 1) The percentage strength of an isotonic boric acid solution given its E value of 0.52. 2) The dissociation factor and percentage dissociation of NaCl as a 2 ion electrolyte. 3) The freezing point of a molal NaCl solution using the electrolyte dissociation factor. It also shows examples of calculating amounts of solutes like boric acid needed to make isotonic solutions given freezing point data.

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    Tonicity

    Uploaded by

    amethyst grande
    141 views2 pages
    This document contains solutions to practice problems related to isotonic solutions and electrolyte dissociation. It provides the steps and calculations to determine: 1) The percentage strength of an isotonic boric acid solution given its E value of 0.52. 2) The dissociation factor and percentage dissociation of NaCl as a 2 ion electrolyte. 3) The freezing point of a molal NaCl solution using the electrolyte dissociation factor. It also shows examples of calculating amounts of solutes like boric acid needed to make isotonic solutions given freezing point data.

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    tonicity

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    This document contains solutions to practice problems related to isotonic solutions and electrolyte dissociation. It provides the steps and calculations to determine: 1) The percentage strength of an isotonic boric acid solution given its E value of 0.52. 2) The dissociation factor and percentage dissociation of NaCl as a 2 ion electrolyte. 3) The freezing point of a molal NaCl solution using the electrolyte dissociation factor. It also shows examples of calculating amounts of solutes like boric acid needed to make isotonic solutions given freezing point data.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    141 views2 pages

    Tonicity

    Uploaded by

    amethyst grande
    This document contains solutions to practice problems related to isotonic solutions and electrolyte dissociation. It provides the steps and calculations to determine: 1) The percentage strength of an isotonic boric acid solution given its E value of 0.52. 2) The dissociation factor and percentage dissociation of NaCl as a 2 ion electrolyte. 3) The freezing point of a molal NaCl solution using the electrolyte dissociation factor. It also shows examples of calculating amounts of solutes like boric acid needed to make isotonic solutions given freezing point data.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 2

    Solution of practice problems

    1. Calculate the percentage strength (w/v) of an isotonic solution of boric acid (E


    value = 0.52)
    1 g boric acid = 0.52g NaCl
    0.9% NaCl is isotonic solution
    Answer:

    2. NaCl dissociate is a 2 ions electrolyte, dissociating 90% in certain


    concentration Calculate
    (a) its dissociation factor
    Answer: On the basis of 90% dissociation, 100 particles of NaCl will yield:
    90 Sodium ions
    90 Chloride ions
    10 undissociating particles

    b. Freezing point of molal solution of NaCl


    Answer:
    The freezing point of molal solution of nonelectrolyte (one gram molecular weight of
    any nonelectrolyte in 1000g water) is equal to (-1.86°C)
    For electrolyte the freezing point is equal to

    -1.86 X i factor = 1.86 X 1.9 = -3.534°C

    3. A solution of anhydrous dextrose (mwt 180) contains 25 g in 500 ml water.


    Calculate the freezing point of this solution.

    Answer: molality is number of moles of solute dissolved in 1000 gm water

    Freezing point of 1molal solution of non electrolyte = -1.86°C


    °C

    6. The freezing point of a 5% solution of boric acid is -1.55°C. How many grams
    of boric acid should be used in preparing 1000ml of an isotonic solution?
    Answer:
    The freezing point of isotonic solution should be -0.52°C
    the concentration of boric acid needed to lower the freezing to -0.52 °C
    Thus to make 1000ml
    1.67% x 1000 = 16.77 g of boric acid

    23. Rx Tetracaine Hydrochloride 0.5%


    Sol. Epinephrine Bitartrate (1:1000) 10
    Purified Water ad 30
    Make isoton. Sol.
    Sig. eye drops.
    The solution of . Epinephrine Bitartrate (1:1000). How many grams of boric acid
    should be used in compounding the prescription?

    Answer:
    E value of tetracaine Hydrochloride (E = 0.18). The prescription calls for 0.15 g
    tetracaine Hydrochloride calculated as shown below
    g Tetracaine Hydrochloride need to make 30 ml
    Step1.
    0.15 x 0.18 = 0.027 g of sodium chloride represented by tetracaine Hydrochloride
    Step 2.
    20 x 0.009 = 0.18 g of sodium chloride in 20 mL of an isotonic sodium chloride
    solution
    Step 3.
    0.18 g (from Step 2) - 0.027 g (from Step 1) = 0.153g of sodium chloride
    required to make the solution isotonic
    But because the prescription calls for boric acid:
    Step 4.
    0.153 g ÷ 0.52 (sodium chloride equivalent of boric acid) = 0.294 g of boric acid
    to be used

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