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    What Is Subcutaneous Mycoses

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    Arslan Saeed
    Subcutaneous mycoses are chronic fungal infections of the skin and subcutaneous tissue caused by soil-dwelling fungi entering through a break in the skin. Examples include sporotrichosis, chromomycosis, and mycetoma. Sporotrichosis is caused by Sporothrix schenckii and causes painless nodules along lymphatics that may persist for years. Chromomycosis is caused by several fungi and presents as wartlike lesions that extend along lymphatics, mainly affecting feet and legs in tropical regions. Mycetoma is characterized by draining sinuses in the feet, hands or back that expel colored fungal grains.

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    What Is Subcutaneous Mycoses

    Uploaded by

    Arslan Saeed
    195 views4 pages
    Subcutaneous mycoses are chronic fungal infections of the skin and subcutaneous tissue caused by soil-dwelling fungi entering through a break in the skin. Examples include sporotrichosis, chromomycosis, and mycetoma. Sporotrichosis is caused by Sporothrix schenckii and causes painless nodules along lymphatics that may persist for years. Chromomycosis is caused by several fungi and presents as wartlike lesions that extend along lymphatics, mainly affecting feet and legs in tropical regions. Mycetoma is characterized by draining sinuses in the feet, hands or back that expel colored fungal grains.

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    microbiology

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    Subcutaneous mycoses are chronic fungal infections of the skin and subcutaneous tissue caused by soil-dwelling fungi entering through a break in the skin. Examples include sporotrichosis, chromomycosis, and mycetoma. Sporotrichosis is caused by Sporothrix schenckii and causes painless nodules along lymphatics that may persist for years. Chromomycosis is caused by several fungi and presents as wartlike lesions that extend along lymphatics, mainly affecting feet and legs in tropical regions. Mycetoma is characterized by draining sinuses in the feet, hands or back that expel colored fungal grains.

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    © All Rights Reserved
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    Download as docx, pdf, or txt
    195 views4 pages

    What Is Subcutaneous Mycoses

    Uploaded by

    Arslan Saeed
    Subcutaneous mycoses are chronic fungal infections of the skin and subcutaneous tissue caused by soil-dwelling fungi entering through a break in the skin. Examples include sporotrichosis, chromomycosis, and mycetoma. Sporotrichosis is caused by Sporothrix schenckii and causes painless nodules along lymphatics that may persist for years. Chromomycosis is caused by several fungi and presents as wartlike lesions that extend along lymphatics, mainly affecting feet and legs in tropical regions. Mycetoma is characterized by draining sinuses in the feet, hands or back that expel colored fungal grains.

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    Date

    SUBCUTANEOUS MYCOSES

    1. WHAT IS SUBCUTANEOUS MYCOSES


    These are chronic, localized infections of the skin and
    subcutaneous tissue following the traumatic implantation of
    the aetiologic agent
    The causative fungi are all soil saprophytes of regional
    epidemiology which are able to adapt to the tissue
    environment and elicit disease is extremely variable.
    EXAMPLES:
     Sporotrichosis
     Chromomycosis,
     Mycetoma,
     Lobomycosis etc
    A. SPOROTRICHOSIS
    Sporothrix schenckii is a DIMORPHIC fungus.
    i.

    OCCURANCE:
    The mold form lives on plants.
    The yeast form occurs in human tissue.
    ii. ONSET OF DISEASE IN HUMAN:
    When spores of the mold are introduced into the skin,
    typically by a thorn, it causes a local pustule or ulcer
    with nodules along the draining lymphatics.
    The lesions are typically painless, and there is little
    systemic illness. Untreated lesions may wax and wane
    for years.
    HUMAN IMMUNODEFICIENCY VIRUS (HIV):
    In (HIV)- infected patients with low CD4 counts,
    disseminated sporotrichosis can occur.

    It occurs most often in gardeners, especially those


    who prune roses.
    iii. REASON:
    They may be stuck by a rose thorn.
    iv. In the clinical laboratory, round or cigar-shaped
    budding yeasts are seen in tissue specimens. In culture
    at room temperature, hyphae occur bearing oval
    conidia in clusters at the tip of slender
    conidiophores( resembling a daisy ). The drug of choice
    for skin lesions is itraconazole ( Sporanox ).
    v. PREVENTION:
    It can be prevented by protecting skin when touching
    plants, moss, and wood.
    B.CHROMOMYCOSIS
    This is slowly progressive granulomatous infection.

    2
    CAUSE:
    It is caused by several soil fungi ( fonsecaea, Phialophora,
    Cladosporium, etc) when introduced into the skin through
    trauma.
    DERMATIACEOUS FUNGI:
    These fungi are collectively called DEMATIACEOUS fungi,
    because their conidia or hyphae are dark coloured, either
    gray or black.
    Wartlike lesions with crusting abscesses extend along the
    lymphatics.
    OCCURANCE:
    In human: The disease occurs mainly in the tropics and is
    found on bare feet and legs.
    In the clinical laboratory: dark brown, round fungal cells are
    seen in leukocytes or giant cells.

    TREATMENT:
    The disease is treated with:
     oral flucytosine or thiabendazole
     local surgery.
    MYCETOMA

    3
    OCCURANCE:
    Soil fungi (Petriellidium, Madurella ) enter through wounds on
    the feet, hands or back and causes abscesses, with pus
    discharge through sinuses. The pus contains compact colored
    granules.
    ACTINOMYCOTIC MYCETOMA: Actinomycetes such as
    Nocardia can cause similar lesions (actinomycotic mycetoma).
    Sulfonamides may help the actinomycotic form.
    TREATMENT:
    There is no effective drug against the fungal form.
    Surgical excision is recommended.

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