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    Genetic Effects of Chernobyl Radiation: Date: Source: Summary

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    Fred Pascua

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    Genetic Effects of Chernobyl Radiation: Date: Source: Summary

    Uploaded by

    Fred Pascua
    29 views2 pages

    Original Title

    Genetic effects

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    29 views2 pages

    Genetic Effects of Chernobyl Radiation: Date: Source: Summary

    Uploaded by

    Fred Pascua

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 2

    Genetic effects of Chernobyl radiation

    Date:
    April 22, 2021
    Source:
    NIH/National Cancer Institute
    Summary:
    Researchers utilized genomic tools to investigate potential health effects of exposure to
    ionizing radiation, a known carcinogen, as a result of the 1986 Chernobyl accident. One
    study found no evidence that genetic changes associated with radiation exposure are
    passed to children, while the second study documented the genetic changes in the tumors of
    people who developed thyroid cancer after being exposed as children or fetuses to the
    radiation released by the accident. Findings are being published close to the 35th
    anniversary of the Chernobyl disaster.

        
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    View of Chernobyl nuclear power plant (stock image).

    Credit: © NickMo / stock.adobe.com

    In two landmark studies, researchers have used cutting-edge genomic tools to


    investigate the potential health effects of exposure to ionizing radiation, a
    known carcinogen, from the 1986 accident at the Chernobyl nuclear power
    plant in northern Ukraine. One study found no evidence that radiation
    exposure to parents resulted in new genetic changes being passed from
    parent to child. The second study documented the genetic changes in the
    tumors of people who developed thyroid cancer after being exposed as
    children or fetuses to the radiation released by the accident.
    The findings, published around the 35th anniversary of the disaster, are from international teams of
    investigators led by researchers at the National Cancer Institute (NCI), part of the National Institutes
    of Health. The studies were published online in Science on April 22.
    "Scientific questions about the effects of radiation on human health have been investigated since the
    atomic bombings of Hiroshima and Nagasaki and have been raised again by Chernobyl and by the
    nuclear accident that followed the tsunami in Fukushima, Japan," said Stephen J. Chanock, M.D.,
    director of NCI's Division of Cancer Epidemiology and Genetics (DCEG). "In recent years, advances
    in DNA sequencing technology have enabled us to begin to address some of the important
    questions, in part through comprehensive genomic analyses carried out in well-designed
    epidemiological studies."
    The Chernobyl accident exposed millions of people in the surrounding region to radioactive
    contaminants. Studies have provided much of today's knowledge about cancers caused by radiation
    exposures from nuclear power plant accidents. The new research builds on this foundation using
    next-generation DNA sequencing and other genomic characterization tools to analyze biospecimens
    from people in Ukraine who were affected by the disaster.
    The first study investigated the long-standing question of whether radiation exposure results in
    genetic changes that can be passed from parent to offspring, as has been suggested by some
    studies in animals. To answer this question, Dr. Chanock and his colleagues analyzed the complete
    genomes of 130 people born between 1987 and 2002 and their 105 mother-father pairs.

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