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Assessment: Hemochromatosis (Iron Overload)

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Hemochromatosis (Iron Overload)

Assessment Patient Image: Include an image that demonstrates the patient’s


expected physical appearance

Subjective: what symptoms will the patient report? Some patients


who have hereditary hemochromatosis may not have symptoms.
➢ Joint Pain
➢ Abdominal pain
➢ Fatigue
➢ Weakness
➢ Impotence

Objective: what signs will you expect to see? What assessments


will you do? What diagnostic tests will you anticipate? What are
the expected results of those tests?

➢ In the heart: arrhythmia and heart failure


➢ In the liver: cirrhosis, enlarged liver, liver cancer, liver
failure
➢ Diabetes
➢ Assessment:
- Family history of hemochromatosis
- Skin assessment to look for bronze colored skin
- Medical history for any complications
➢ Diagnostic test:
- Total iron-binding capacity will be high (reflects
amount of transferrin, a protein that binds with iron
and transports it for storage)
- liver function test abnormal
- serum ferritin will be high (measures amount of
iron stored in liver)
- Genetic testing

Goals ● Patient will reach a serum ferritin level between 50 and 100
ng/mL.
● Patient will avoid foods rich in iron such as red meat,
vitamin C, and alcohol.
● Patient will report joint pain no higher than a 2.
Interventions ● Iron chelating agents such as Deferoxamine, Deferasirox,
(medications) and Deferiprone.

● Iron accumulation can be reduced by dietary changes, such


as avoiding vitamin C and iron supplements, uncooked
seafood, and iron-rich foods.

Rationale (what is the ● Deferoxamine, which chelates and removes accumulated


reason for the iron via the kidneys, can be given IV or subcutaneously.
intervention?)
● Deferasirox and deferiprone are oral agents that chelate
iron. Chelating agents form a complex with iron and
promote its excretion from the body.
Evaluation ● Patient is able to return to serum iron concentrations to a
normal level (50-150 mcg/100mL) keep iron serum
concentrations at a manageable level.
● Check patient’s using pain scale, and patient states of joint
pain no higher than 2.
● The patient reports understanding of changing their diet to
avoid foods rich in iron.

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