Assignment Blood
Assignment Blood
Preamble
This assignment accounts for 65% of the overall mark for the ASDM Class (the individual assignment
accounts for the remaining 35%).
The aims of the assignment are to engender a good understanding of, and skills in, the following
aspects of the ASDM class:
Using a spreadsheet to make sense of data;
Conducting and interpreting statistical analyses on a data set of reasonable size;
Using multi-criteria decision analysis to structure and inform a decision.
Presenting your analyses in visual and written form;
The assignment is group based. Because of the amount of work involved in this assignment you
should work with a group of other students on this assignment.
The report for this assignment should have three parts. The division of marks and a page length
guide for the three parts is summarised below. All parts are compulsory – your group will not
receive an overall mark unless you submit a credible attempt for each part.
The overall report length must not exceed 30 pages, including appendices.
Note: we assume a page to be A4, single-spaced, 11 point characters - i.e. around 300 words.
You should submit one report per group. You should also include:
A copy of the Excel file used for your analysis for Part 2.
A copy of your VISA file used for your analysis for Part 3.
You will be advised of the deadline for submission of this assignment, and subsequent return of
marks, by your MBA Administrator.
A copy of the blank assignment feedback form is available on Myplace so that you have visibility of
the marking criteria and marks breakdown.
This assignment has been set by the MBA ASDM Teaching Team 2020-21.
Introduction to the Assignment Context
The Manager of a local hospital has asked for your help. Data has been collected for the last 4
months in the hospital on patients who have had a blood transfusion. The data have been input into
a spreadsheet. Unfortunately there is no-one in the Department with the necessary skills to analyse
the data. You have been asked to analyse the data and provide a suitable management report for
the Manager.
Note: the data provided is real and comes from a Scottish hospital but the name of the actual
hospital has been kept confidential.
As most people are aware, blood and blood products are a key resource for a health service and are
used in providing emergency treatment, in surgical treatment (operations) and in routine care. There
are 4 main blood groups (known as ABO): A, B, O and AB. In addition, people either have, or do not
have, the Rhesus factor on the surface of their red blood cells. This is usually indicated by 'RhD
positive' (does have) or 'RhD negative' (does not have) suffix to the ABO blood group. This means
that generally there are 8 main blood types. (Note; this is an oversimplification for the purpose of
this assignment. There are in fact over 30 different blood types). Table 1 shows the 8 main blood
types and the percentage of the UK population in each blood type category. Table 2 shows a number
of international comparisons.
ASDM Assignment 2
Table 2 ABO and Rh distribution by country
Source: Wikipedia
ASDM Assignment 3
Blood Transfusion
Transfusion medicine is a specialized branch of haematology that is concerned with the study of
blood groups, along with the work of a blood bank to provide a transfusion service for blood and
other blood products. Across the world, blood products must be prescribed by a medical doctor
(licensed physician or surgeon) in a similar way as medicines. Much of the routine work of a blood
bank involves testing blood from both donors and recipients to ensure that every individual recipient
is given blood that is compatible and is as safe as possible. If a unit of incompatible blood is
transfused between a donor and recipient, a severe acute haemolytic reaction, renal failure and
shock are likely to occur, and death is a possibility.
Patients should ideally receive their own blood or type-specific blood products to minimize the
chance of a transfusion reaction. Risks can be further reduced by cross-matching blood, but this step
may be omitted when blood is required for an emergency. Cross-matching involves mixing a sample
of the recipient's serum with a sample of the donor's red blood cells and checking if the mixture
agglutinates, or forms clumps. If agglutination is not obvious by direct vision, blood bank technicians
usually check for agglutination with a microscope. If agglutination occurs, that particular donor's
blood cannot be transfused to that particular recipient.
Blood Compatibility
Although ideally patients should receive matched blood products, in practice some blood group
types are compatible with others. Table 3 shows the compatibility between donor and recipient. So
for example, a patient who is A- can be given A- blood (their own type) but also O- blood. In fact,
examination of Table 3 indicates that O- blood is compatible with all the other blood types and can
be used on all patients. O- blood products are often referred to as “universal” as they can be used
for all patients. This can be extremely useful, for example, in emergencies when a blood transfusion
is needed urgently and there may not be time to identify the patient’s actual blood type.
Note - Assumes absence of atypical antibodies that would cause an incompatibility between donor
and recipient blood, as is usual for blood selected by cross matching.
Recipient[1] Donor[1]
O− O+ A− A+ B− B+ AB− AB+
O−
O+
A−
A+
B−
B+
AB−
AB+
ASDM Assignment 4
Blood Donations
In the UK, for example, blood supplies are generally obtained through a national blood donor service
where citizens voluntarily donate blood, usually twice a year. After donation, the blood goes off to
specialist laboratories for routine testing. In Scotland there are two testing labs, in Glasgow and
Edinburgh, both working round the clock. The following tests are carried out on every donation:
HIV - All donations are tested for antibodies to the HIV1 and HIV2 viruses which cause AIDS
Hepatitis viruses - Hepatitis is an inflammation of the liver which may cause jaundice and
sometimes liver failure. All donations are tested for hepatitis B and C.
Syphilis - Syphilis, a sexually transmitted disease, can be passed on through blood, so all
donations are tested.
Typically a donation will have been processed and tested and ready for use within 48 hours. Blood
has a very short shelf life of around 35 days and has to be stored and distributed under stringent
conditions.
The Situation
The hospital manager you have been asked to help faces a difficulty. Although O- blood is universal,
in the sense that it can be used safely with virtually all patents, it is also in short supply. Table 1
indicates that only around 7% of the UK population is O- and, by implication, only around 7% of
blood donations will be O-. The manager would prefer medical staff to be using appropriately
matched blood wherever possible and restricting the use of O- blood to those patients who really
need it: those patients who are actually O- (since from Table 3 there are no other compatible blood
types) and patients who require emergency blood transfusion where there is no time to check their
blood type.
On the other hand, the manager does not want donated blood to be wasted, which can happen if
blood is not used within its shelf life (each unit of blood is marked with an expiry date). As a result,
she has carried out some data collection in the hospital over the last six months. A record has been
kept of every patient who received O- blood during that period. The following data has been
collected on each patient (and is available in the accompanying Excel file for this assignment).
ASDM Assignment 5
Assignment Tasks
The Executive Report will be used by the manager as well as senior management at the hospital. This
report should present your recommendations and other key findings. This report should be
supported by the evidence presented in the technical reports of your analysis.
Your first task is to conduct a thorough analysis of the data presented and to write a report for the
hospital manager summarising the key findings in relation to use of O-blood within the hospital. The
manager is interested in acquiring a better understanding of hospital’s demand for blood to inform
purchasing and storage decisions. Your analysis should include, but not be restricted to, analysis of
demand on a daily basis as well as the aggregate demand over a 35 day period which corresponds to
shelf life. Your analysis should include an assessment of the uncertainty in demand.
HINT: carefully consider the role of the Central Limit Theorem in modelling daily demand compared
with aggregate demand over a 35 day period.
The main report should be written for the manager whose knowledge of statistics and analysis is
very limited. You may use appendices to the report to show any technical analysis that you have
conducted.
As part of a wider improvement initiative, the hospital manager is considering how the hospital’s
blood bank service can be made more efficient and more effective. At present, the main blood bank,
where donated blood is stored, is at a large regional hospital about 80km away. The local hospital
has only a small blood bank facility where typically only a few days’ supply of blood can be safely
stored. The regional hospital routinely supplies blood on an anticipated or forecast basis and these
stocks are replenished every few days or, in the event of a stock shortage at the local hospital, can
be shipped through at a few hours notice (although at considerable cost). The hospital manager is
reviewing a number of options and has heard (vaguely) about the use of multi-criteria methods. She
has asked you to develop an outline multi-criteria model to help her reach a decision between the
options.
Option A: continue the existing system. In one sense this would be the easiest option. However, it
also carries some risks as the hospital occasionally experiences times when it runs out of stocks of
certain blood types and emergency supplies have to be sent across from the regional hospital. The
cost of this is high (because of the specialist transportation needed) contributing to budget
ASDM Assignment 6
overspend and there are also clinical risks for patients. There have also been occasions in some
winters where emergency supplies have not been able to be sent because of severe weather
conditions.
Option B: expand the blood bank at the local hospital to allow it to carry its own stock requirements
in full. The local blood bank would then be effectively independent which would contribute to
minimising risk to patients of blood supply shortage. However, the capital cost of this would be high
(roughly estimated at about £0.75 million) and in the current economic climate might be difficult to
obtain. Once built the hospital would also incur higher annual running costs (again roughly estimated
at around £175,000 per year). Senior medical staff might be unhappy at this, and have commented
that the money would be better spent employing more doctors and nurses.
Option C: improve the local hospital’s Management Information System (MIS) and stock control
system (SCS). At present the local hospital does little to try to predict blood use requirements or to
manage its blood stocks effectively. This option would focus on two things. First, better analysis and
forecasting of blood use requirements in the hospital linked to the scheduling of patient treatments
and surgical operations. It is felt that this would enable the hospital to better and more accurately
predict the blood it requires. Secondly, investing in an up-to-date stock control system so that blood
supplies are more effectively tracked and monitored to reduce wastage, stock levels and associated
costs. Most of the effort under this option would go into the development of better IT/IS systems.
Anticipated development costs are around £100,000 with ongoing costs on an annual basis of
around £50,000. The exact tangible benefits from this are very difficult to quantify although the
manager thinks that wastage will be reduced.
Required: Analyse the decision problem facing the hospital manager using multi-attribute value
analysis supported by the V.I.S.A software
HINT: Each group member should role-play different actors within this decision problem. For
example, roles include the analyst/facilitator and different stakeholders. This will give you the
opportunity to experience managing/participating in decision analysis.
You should include carefully chosen visual displays to illustrate your report.
ASDM Assignment 7