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College of Nursing Pharmacy and Allied Health Sciences

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COLLEGE OF NURSING PHARMACY AND ALLIED HEALTH SCIENCES

Name: TANTICO, LADYFAIR G. Date: July 16, 2021


Section: B

Subject PHARM 309


Title Gout and Hyperuricemia
Activity No No.
Introduction WHAT IS GOUT AND HYRURECEMIA?
Gout is a condition characterized by the deposition of monosodium urate
crystals in the joints or soft tissue. The four phases of gout include
asymptomatic hyperuricemia, acute gouty arthritis, intercritical gout and
chronic tophaceous gout. The peak incidence occurs in patients 30 to 50 years
old, and the condition is much more common in men than in women. Patients
with asymptomatic hyperuricemia do not require treatment, but efforts should
be made to lower their urate levels by encouraging them to make changes in
diet or lifestyle. Acute gout most commonly affects the first metatarsal joint of
the foot, but other joints are also commonly involved. Definitive diagnosis
requires joint aspiration with demonstration of birefringent crystals in the
synovial fluid under a polarized light microscope. Treatment includes
nonsteroidal anti-inflammatory drugs (NSAIDs), colchicine, corticosteroids and
analgesics. In patients without complications, NSAID therapy is preferred.
.
.
Objective(s) At the end of the activity, the student should be able to:
1. Have knowledge about gout and hyperuricemia.
2. Will know the treatment and proper management of gout and
hyperuricemia.

Materials and Gadget (laptop, PC, smartphone)


Equipment Data connections
Internet source/Book

Laboratory Questions:

Identify the symptoms, causes, risk factors and medications for Gout. Fill the table below.

Symptoms Causes Risk factors Medications

 Intense joint pain  Hyperuricemia  Diet  Colchicine


 Lingering  Weight- obesity  Nonsteroidal
discomfort  Purines- eating  Medical anti-
 Inflammation and foods rich in conditions inflammatory
redness purine such as red  Certain drugs(NSAIDs)
 Limited range of meat and organ medications-
motion meats, beans including thiazide  Corticosteroids-
diuretics, such as
 Alcoholic angiotensin- prednisone
beverages converting
enzyme (ACE)  Medications that
inhibitors and block uric acid
beta blockers production-such
as allopurinol and
 Family history febuxostat
COLLEGE OF NURSING PHARMACY AND ALLIED HEALTH SCIENCES
of gout
 Age and sex  Medications that
 Recent surgery improve uric
or trauma acid removal-
Drugs such as
probenecid
(Probalan)

References:
https://www.who.int/csr/resources/publications/biosafety/WHO_CDS_EPR_2006_6.pdf

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