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Post-Lab Report: de Luna Doronila Mendoza Villarosa Group 6

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Post-Lab Report De Luna

Group 6

Doronila
5 & 6
LAB Mendoza

Villarosa
Lab 5: Organic
Reaction Mechanisms
(Guide Questions)
1. Reaction mechanism is
an overall explanation of
how electrons move to
form new bonds or break
existing ones during a
reaction.
2. Reaction mechanisms are drawn
using curly arrows to denote the
movement of the electrons in each
step of the reaction. It is very
important that the arrow starts
where the electrons are and points
towards where the electrons go.
Overall there are three different types of curly arrows:

Arrows that break bonds. The


arrow's root is drawn to begin in
the bond which is broken. The
arrowhead points to the atom or
part of the molecule which will
accept the electron pair from the
bond.
Arrows that make bonds. The
arrow's root is drawn to begin in the
lone-pair or the negative charge of
the nucleophile which will attack. The
arrowhead is drawn to point at the
electrophile where the nucleophile will
attack or the new bond which will be
formed as a result of the reaction.
Arrows that make and break
bonds at the same time. The arrow's
root is drawn to begin in the bond
which is being broken and the
arrowhead is drawn to point at the
electrophile where the nucleophile will
attack or the new bond which will be
formed.
3. Renosance is used in
chemistry to describe
situations when a molecule's
actual electronic distribution
is a mixture of numerous
contributing structures.

Examples: carboxylate
anion, benzene ring,
and protonated
carbonyl compound
4. In Electrophile Addition, the An SN1 reaction is a
initial step is an electrophile attack nucleophilic substitution
an electron-rich part of the process in which only 1
molecule while in Nucleophile component determines the
Addition, the 1st step is to connect rate while in an SN2 reaction,
a nucleophile to a positive electron- it involves 2 components in
deficient part of molecule. rate-determining.
In E1 elimination, it happens in
two phases, but one of the
reactants is the sole thing that
slows down the reaction while in
E2 elimination it happens in just
one phase but two of the
reactants restricts the pace of
its reaction.
5. charge: negatively
charged species will be size: smaller nucleophile
more nucleophilic than is a stronger nucleophile
its neutral counterpart
solvent: protic solvent electronegativity: less
makes nucleophile less electronegative atom is
reactive than in an more nucleophilic, all
aprotic solvent other things being
equal
Stereochemistry: The reactions
6. Overall functional group: can be specified as stereospecific
The functional group is or create enantiomers which are
converted into other two molecules with the same
functional group. chemical formula but different
3d orientation.
Regioselectivity: The
outcome refers to which
part the reagent adds to
which part of the double
bond.
7. Markovnikov’s Rule Zaitsev’s Rule
The chemical basis for Markovnikov's Rule is Zaitsev's rule predicts that in an
the formation of the most stable carbocation elimination reaction, the most substituted
during the addition process. The addition of
the hydrogen ion to one carbon atom in the product will be the most stable, and
alkene creates a positive charge on the other therefore the most favored. The rule
carbon, forming a carbocation intermediate. makes no generalizations about the
The more substituted the carbocation, the stereochemistry of the newly formed
more stable it is, due to induction and alkene, but only the regiochemistry of
hyperconjugation. the elimination reaction.

Lab 6: Preparation
of Organic Compunds
(Guide Questions)
1. Organic Synthesis is significant in
the field of Veterinary Medicine
because, with different reactions made
from Organic Compounds, it can be a
way to produce different kinds of
products and drugs that can create big
impacts on animals and even humans.
2. • substitution
• addition
• elimination
• oxidation
• reduction
• rearrangement
3. Catalyst is any substance Catalysts are essential in
that increases the rate of a transforming organic compounds
reaction without being into useful building blocks, which
consumed. Enzymes are can be homogeneous,
naturally occurring catalysts heterogeneous, or supported
that catalyze many vital depending on their nature and
biochemical reactions. activity in catalytic reactions.

4. Illustrate and
explain the organic
synthesis mechanism
of the following
organic compounds:
Acetanilide
Dibenzalacetone
p-Nitro acetanilide
2-naphthol aniline dye
Documentation: Virtual Simulation
Thank You!

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