State of The Industry Report Next-Gen MAterials

STATE OF THE
INDUSTRY REPORT
BONUS
SECTION:
MARKET
NEXT-GEN MATERIALS PROJECTION
June 2021
Cover image: PANGAIA FLWRDWN™
Fitted Short Puffer Jacket
Source: https://thepangaia.com/
DISCLAIMER
The Material Innovation Initiative is not a registered investment adviser (as defined in the Investment Advisers Act of 1940,
15 U.S.C. § 80B-1, et seq., and the rules and interpretations promulgated thereunder) and cannot transact business as an investment
adviser or give investment advice. Any document or information created or shared by MII does not constitute advice concerning
the value of any security or the advisability of buying, selling or otherwise investing in any security.
The information provided in this report is for general information purposes only. All information in this report is provided in good faith,
however, we make no representation or warranty regarding the accuracy or completeness of this information. If you would like to contact
us about the contents of this report, please email info@materialinnovation.org.
2 © 2021 Material Innovation Initiative

EXECUTIVE SUMMARY
(AND HOW TO USE THIS REPORT)
The Material Innovation Initiative (MII) is thrilled materials, and collaborating with next-gen material
to offer this first-of-its-kind State of the Industry startups to create new products. All this leads to
Report, and in fact, to announce the emergence acceleration of commercialisation and scale-up
of the next-gen material industry. production of next-gen materials to replace their
conventional counterparts.
In this report, you will find research, analysis, and
insights to guide your understanding of this nascent In each section of the 3 i’s, we present data and
industry. Whether you are an entrepreneur or statistics to give you an overview of the current
startup, investor or corporate, you can still join this state. We then dive into Insider Insights for more
space as a first mover. It’s that new. flavor of these industry players: What are the main
risks and opportunities? Who’s doing what? Who
We suggest that you do not skip Part A, which might be the winner?
includes the Introduction. That gives you the
important context for what comes next. You don’t Part C explores the driving forces accelerating
want to miss the founders’ story (and why we the growth of the next-gen material industry,
can predict the future). specifically: advancements in material science and
technology, changing consumer preferences, and
In Part B, we introduce the three categories regulatory trends.
of key stakeholders in this industry, or the
3 i’s: Innovators, Investors, and Industry Brands. Because this is the first ever state of the industry
Innovators are companies, including startups, that report, the Material Innovation Initiative worked
create innovative next-gen materials. Investors with our research partner SPEEDA Edge on
provide the necessary funding for Innovators’ R&D a bonus section to address the most asked
activities and business growth. Industry Brands are question: how big will this market be in the
the established companies that are the biggest years to come?
buyers and users of materials. Think Adidas, IKEA,
and Bentley. Industry Brands can play multiple The next-gen material industry is both rapidly
important roles in the ecosystem, including funding emerging and changing. If you find something
both internal and external innovation initiatives, that should be in our next report, please let us
switching to next-gen materials as their raw know via this form.
The Material Innovation Initiative (MII) is a nonprofit that accelerates the development
of high performance, animal-free, and more sustainable materials for the fashion,
automotive, and home goods industries. MII partners with startups, investors, brands,
and scientists to bring these next-gen materials to market. Visit MaterialInnovation.org
for more details.

STATE OF THE NEXT-GEN MATERIAL
INDUSTRY AT A GLANCE
$1.29
74
14
BILLION
95 41 MICROBE-
UNIQUE PLANT- DERIVED
TOTAL NUMBER INVESTORS DERIVED
OF NEXT-GEN INVESTED
MATERIAL (2015 - MAY 14, 2021)
COMPANIES 7 6
AS OF APR 30, 2021
MYCELIUM RECYCLED
$504 $599 MATERIAL
49
LEATHER
9
SILK
7
WOOL MILLION MILLION 4 3
RAISED IN 2020 BLENDS CULTURED
(NEARLY THE SAME TOTAL AMOUNT ANIMAL CELLS
6 5 1 AS THE PREVIOUS RAISED BY THE TOP
DOWN FUR EXOTIC SKINS 4 YEARS COMBINED) FUNDED COMPANY NUMBER OF COMPANIES BY MAIN INPUT
$293 35
38 OUT
OF 40
42 MILLION DEALS
LEADING FASHION BRANDS
NEW COMPANIES LARGEST FUNDING ACTIVELY SEARCHING FOR
FORMED SINCE 2014 ROUND 2020 (2015 - MAY 14, 2021) NEXT-GEN MATERIALS
Source: Material Innovation Initiative

*Note: Some companies create more than one next-gen material.
**Note: To simplify the broad landscape of formulation and processing approaches for
next-gen materials, MII categorizes next-gen innovation by main input (greater than 50%).
IN
Look for the IN logo throughout this report

for next-gen material industry insights.

CONTENTS
PART A: A NEW INDUSTRY IS BORN 6 PART C: OTHER DRIVING FORCES 47
1. Introduction 7 7. Advancements in Science and Technology 53

– Founders’ Story 8 – Biotechnology 48
– Where Does the Industry Stand in 2020? 9 – Biobased Chemistries 49
– 2021: In the News 12
8. Consumer Preference 50
2. Definition and Scope 13
– What Are “Next-Gen Materials”? 13 9. Regulatory Challenges and Opportunities 53
– Disruptive Textile Technology 13 – Increased Concerns About Sustainability 53
– Innovators, Investors, And Industry Brands 13 – I ncreased Focus on Animal Welfare 53
Including Bans on Animal-Based Materials
3. Next-gen Material Science 101 14 – Low Regulatory Burden to Market Entry 54
– Labelling Restrictions 54
PART B: KEY STAKEHOLDERS 18 10. Conclusion 55

OR “THE THREE I’S”
4. Innovators 19 BONUS: MARKET SIZE AND 57

– Overview 19 FORECAST BY SPEEDA EDGE
– Trend 23
– Insider Insights 24 A Disrupted Animal Agriculture Industry 59
5. Investors 28 The Turn Against Plastic 59

– Overview 28
– Capital 33 The Relative Lack of Barriers 60
– Companies 34
– Insider Insights 36 REFERENCES 61
6. Industry Brands 38
– Overview 38
– Insider Insights 43

PART A:
A NEW INDUSTRY
IS BORN

1. INTRODUCTION
Have you heard of the next-gen material industry? the animal material itself is the most profitable
Chances are you haven’t. product.2 Industrial animal farming is a leading
cause of many of the pressing problems of our
This report is truly the first of its kind. The Material time, including climate change, environmental
Innovation Initiative introduces and provides degradation, public health risks, and animal
early insights into the nascent industry of next- cruelty. Given that at least two thirds of a brand’s
gen materials, a term we coined based on our environmental footprint can be attributed to its
nomenclature assessment study, to describe
1
choice in raw materials,3 if we hope to move rapidly
high performance, more sustainable alternatives toward a more sustainable materials industry,
to animal-derived materials (see section 2 for we need alternatives to animal materials.
full definition.)
Adidas plant-based sneakers
Conventional livestock-derived materials such as

leather, fur, silk, wool, down, and exotic skins, are
widely used in the fashion, home goods,
and automobile industries. That animal-based
materials are simply byproducts from industrial
animal agriculture that primarily supplies to
the food industry, is a common misconception.
Leather, for example, is the second most profitable
product of a cow; and for fur, silk, and exotic skins,
IN
“The term next-gen cues innovation, and may

better describe a new category of materials which
has multiple characteristics (i.e., sustainable,
animal-free, and high performance).”
- North Mountain Consulting Group

“Stephanie Downs, MII’s other co-founder,
and I have seen this sort of industry-
wide change happen before, and today’s
materials industry looks very familiar to us.”
- Nicole Rawling, co-founder and CEO
of Material Innovation Initiative
IN
FOUNDERS’ STORY (AND WHY WE CAN PREDICT THE FUTURE)
Both Nicole and Stephanie came from the world Today, plant-based meat options sell out in major fast-
of alternative protein. Think plant-based meat like food chains like Burger King; you can find plant-based
Beyond Meat and real meat grown through tissue meat right alongside beef in the grocery store; major
engineering without the need to kill cows. When they international food companies like Nestlé and Tyson
started working in that industry, there were veggie are investing in alternative proteins. Governments all
burgers, but not what most people now call ‘plant- over the world are working to accelerate the alternative
based meat.’ In fact, the term ‘alternative protein’ didn’t protein industry. Today in Singapore, you can actually
exist when they started building that ecosystem. have a meal cooked with cultivated meat (real meat
grown through tissue engineering) at a restaurant or
The world woke up to the alternative protein industry even have it delivered to your home.
when Beyond Meat went public in 2019, and its stock
price soared 163% on the first day of trading and This massive growth of the alternative protein industry
around 800% within a few months. But that apparent happened in just a few years. That is the power of
overnight success was 10 years in the making. The creating a collaborative ecosystem, directing R&D
company was founded in 2009 with the clear vision of toward the most critical areas, and shaping the public
making meat not for vegetarians, but for mainstream message around sustainable technology.
consumers. This mindset change was the tipping
point that created a new industry. Everything “People who have missed the boat are now looking
changed when companies began thinking about for the next Beyond Meat,” said Nicole, “I say look no
meat-eaters, analyzing what they liked about meat, further than the next-gen material industry. Next-gen
and then working to replicate it. Everything shifted materials are now where alternative protein was about
when companies stopped asking consumers to 5 years ago.”
sacrifice, but rather used science and technology to
give consumers what they wanted: the taste they were
used to with the benefits of being better for the planet
and animals.

WHERE DOES THE INDUSTRY STAND IN 2020?
Within the categories of next-gen materials, all eyes Control and Prevention stated that the majority of
are on leather replacements. This is not surprising human pandemics start in animals and the next
as leather is particularly ubiquitous across the pandemic isn’t a matter of if, but when.7 A recent
fashion, automotive, and home goods industries, report by Boston Consulting Group predicted that
with a global value of 414 billion USD in 2017.4 peak meat consumption in North America and
Europe will occur by 2025.8 When the demand for
The Covid-19 pandemic highlighted the beef drops, so will the supply of leather, and leather
vulnerabilities in existing industries and ignited prices will rise. The same report also estimates
changes across the board. In this period of crisis, that if meat consumption declines as expected,
some emerging industries and companies have 1 gigaton of carbon dioxide equivalents will have
experienced unprecedented growth. While Amazon been avoided within the next 15 years,9 and
and Zoom were among the biggest winners of farmland equivalent to the area of the UK will have
2020, for obvious reasons,5 consumers’ heightened been freed from supporting livestock.10
IN
“The most significant quantum leap advancements

in technology are enabled by innovations in material
science. Material technologies are among the only that
can impact all fields, fulfilling basic human needs and
improving the quality of life on the planet.”
- Material Impact, venture capital and company builder
awareness and concerns about industry practices 2020 highlighted that raising animals for their skin,
and sustainability issues have also helped industries fur, or feathers can be a risky business with low
like alternative protein to thrive in what was margins and high variability. Going forward, the
otherwise a dire business environment. greatest opportunities lie in developing technology
and materials that inherently meet market demand
When millions of mink in fur farms were culled to for sustainability, style, and performance.
stop the spread of a Covid-19 variant in 2020,6 the
world saw that relying on animals for materials Consumers indicate they are ready to support this
leaves the supply chain vulnerable in ways that positive change. In a study of consumers in the U.S.,
next-gen materials do not. The World Health 55% of the respondents said they would prefer a
Organization and the U.S. Centers for Disease leather alternative (see section 8 for more details).

MII has met with 40 leading fashion brands, and all but
two are actively searching for next-gen materials to
integrate into their supply chains.
IN
Fashion brands recognize the trend toward more an active role in promoting R&D for next-gen
sustainable and animal-free materials. materials. In 2020, exciting collaborations included
Lululemon, Kering, Adidas, and Stella McCartney
Just as the food industry initially struggled to partnering with Bolt Threads, and Ralph Lauren and
achieve the taste, price, and convenience that Allbirds investing in Natural Fiber Welding. These
customers desire, the current materials industry major brands have the infrastructure, capital, and
does not yet produce sustainable options at scale distribution networks that startups need to scale their
that meet brands’ performance, aesthetic, and price ideas and bring materials to market. We anticipate
requirements. But some brands are already taking more of these partnerships as the industry develops.
11
10
12
With clear interest from consumers and brands,

investors are taking notice of the opportunities
for significant financial, environmental, and social
return by investing in next-gen material companies.
Investors see the massive potential of this space
and are eager to invest in startups that can
transform the materials industry. In fact, there are
currently more interested investors than suitable
investment opportunities.
There is significant demand for next-gen materials,

but not enough supply to meet the sustainability,
performance, aesthetic, scale, and price needs of
brands and consumers. The Material Innovation
Initiative addresses the urgent need to facilitate
collaboration between industry players. including
entrepreneurs, investors, scientists, material
companies, and brands to increase the number of
companies in this space and support the existing
material companies.
“If there’s anything I’ve learned from my time

working with disruptive technologies, it’s that a
rising tide lifts all boats,” said Nicole Rawling, MII’s
co-founder and CEO. And in the next-gen materials
industry, the tide is indeed rising.
Natural Fiber Welding Production

2021: IN THE NEWS
MARCH 2021 MARCH 2021

Hermès partnered with mycelium-based Stella McCartney launched her first alternative
material startup MycoWorks to reimagine its leather garment made with Mylo by
classic Victoria shopper in alternative leather.13 Bolt Threads.14

2. DEFINITION AND SCOPE
WHAT ARE “NEXT-GEN MATERIALS”?

For the purpose of this report, the term “next-gen Examples of exclusions from this definition:
materials” refers to materials that are livestock-
free direct replacements for conventional Materials that are not directly replacing
animal-based leather, silk, down, fur, wool, and animal-based materials;
exotic skins. These replacement materials use Materials designed for use in construction,
a variety of biomimicry approaches to replicate thermal cooling, and packaging solutions
the aesthetics and performance of their animal- that traditionally do not make use of animal-
based counterparts. based materials;
Recycling and upcycling technologies;
Wearable technologies;
Dye, cut, trim, or other manufacturing and
supply chain technologies.
Leather Silk Fur Down Wool Exotic skins
DISRUPTIVE TEXTILE players and technologies may become promising

TECHNOLOGY feedstocks or resources for next-gen material
innovation, MII is creating a separate database to
Synthetic materials are prevalent in today’s world. provide next-gen material innovators an easy way
Sustainable innovation in synthetics such as to find potential collaborators.
bio-based, biodegradable, or recycled polyester
or polyurethane, and in sustainable renewable- INNOVATORS, INVESTORS,
sourced fibers such as cellulosics and natural fibers, AND INDUSTRY BRANDS
could have a broad impact in the plastics and
textiles industries as a whole and, in some cases, in The scope, definition, limitations, and assumptions
the next-gen materials space. Material innovations underpinning the analysis of key industry
purely to replace polyester, however, are outside the stakeholders are stated in each section in
scope of this report. To the extent that these broad this report.

3. NEXT-GEN MATERIAL
SCIENCE 101
Materials science and engineering focuses on To simplify the broad landscape of formulation
the interplay of material composition, structure, and processing approaches for next-gen materials,
processing, and properties to achieve specific MII categorizes next-gen innovation by main input
performance for a target application. In next-gen (greater than 50%):
materials science, the same principles are
applied to develop materials that mimic animal- Plant-derived: applies to materials derived from
derived materials or their current generation, virgin or waste/byproduct plant matter. For
unsustainable replacements (e.g., polyurethane simplicity, fungi (fruiting body) and algae inputs
leather). The science of incumbent animal-derived are included in this category, even though they
materials serves as a materials design guide, with are not plants.
the incumbents’ performance as a benchmark. For M
ycelium: applies to materials that utilize the
example, next-gen leather materials should mimic root-like structure of some fungal species called
the interconnected collagen network of leather mycelium. This category is distinctive from the
in order to replicate its toughness and strength, plant-derived category due to the rich activity of
while next-gen silk should mimic the silk protein next-gen innovation involving mycelium.
and continuous fiber structure to achieve elasticity M
icrobe-derived: applies to materials that utilize
and luster. Designing next-gen materials employs cellular engineering approaches such as cell
biomimicry, i.e., replicating incumbent animal- culture or fermentation processes to produce
derived material function, and may also products such as proteins and biopolymers for
employ bio-utilization, i.e., using naturally next-gen material formulations.
occurring materials as feedstock.15 C
ultured animal cells: applies to materials that
utilize tissue engineering approaches to grow
animal cell constructs in the laboratory.
R
ecycled material: applies to materials that
utilize recycled plastic or textile feedstock as a
main input.
B
lend: applies to materials that use a blend of
components not well-captured by any of the
above categories.
LUXTRA clutch purse made with

Fruitleather Rotterdam leather

Figure 3.1 Conceptual landscape of next-gen leather materials
Source: Material Innovation Initiative
IN
“The transformation of orange peel and algae into fabric

and grape residue into plant-based leather are just a few of
the great ideas that have been realized. I’m convinced that
technical innovations will be the solution to many of the
environmental challenges the textile industry is facing and
will contribute to a more sustainable consumption.”
- Karl-Johan Persson, H&M Group

Using Figure 3.1 above as a reference, there are a
variety of approaches for producing a next-gen
material such as leather.
The most popular approach involves the use of

plants (and/or fungi, algae) as feedstock for next-
gen materials. Virgin plant matter or the byproduct/
waste of plant agriculture provides a rich,
regenerative set of resources from which to build a
functional material formulation. The plant matter
may be harvested and incorporated with minimal
chemical alteration, such as powdered apple peels
(e.g., Beyond Leather), pineapple leaf fibers (e.g.,
Piñatex), or Kapok fiber (e.g., Flocus). In other cases,
the plant matter is chemically/biologically modified,
or manipulated to a new form, such as with
cellulosic fibers from dissolved and regenerated
orange juice waste (e.g., Orange Fiber), the welding
of natural fibers (e.g., Natural Fiber Welding), and
polymer resins derived from plant oils (e.g., the
bio-based PU or rubber of several next-gen
leather formulations). DeLaunay jacket made with Piñatex® by Ananas Anam
Due to the unique nature of the branched, fibrous

structure of the chitin-rich material, mycelium has Another formulation pathway Involves cell
found specific use as an alternative to leather. The culture in the laboratory, but instead of using
mycelium is grown in indoor farms on feedstock cells to grow tissues, cells are used as factories
such as plant waste and then processed into for producing specific compounds. These cells
leather-like sheets. With over seven innovators can be from a variety of sources (e.g., animal,
employing this fungi-derived material in their plant, bacteria, yeast) and are placed in bioreactor
formulations, mycelium deserves its own category chambers, often with plant-based feedstock, with
within the ecosystem of next-gen leather materials. an optimized environment for production of the
target compound. In one example, the cells may
The cultured animal cell or tissue engineering produce native molecules, like bacteria generating
approach takes a one-time harmless biopsy from cellulose or mammalian cells generating collagen.
animals and grows these cells on scaffolds in the In other techniques such as precision fermentation,
laboratory into tissues such as skin. This approach is the cells, typically microbes such as yeast or
distinctive from the other process flows in that the bacteria, are genetically engineered to produce
semi-finished product is expected to be identical foreign molecules, such as recombinant proteins,
to the incumbent material - for next-gen leather, biopolymers, or chemical precursors. In either
a sheet of animal hide (skin). Currently, the tissue approach, the molecules are harvested from the
engineering approach has only been attempted cell culture and converted into components such
with next-gen leather (e.g., VitroLabs), but as fibers and resins which can then be used in
theoretically, exotic skins could be produced with the next-gen material composition. The majority
the same technology. With further advancement of next-gen innovation employing these cellular
in follicle tissue engineering, next-gen fur, wool, engineering approaches is in leather, with bacterial
or down could also be feasible, where cell-based cellulose (e.g., Malai) or recombinant collagen
constructs allow hair or feathers to be lab grown. (e.g., Provenance Bio) serving as the key target

components, and in silk, with spider silk protein such as nonwoven fibers in next-gen down (e.g.,
as the target output (e.g., AMSilk). However, these Save The Duck) or yarns for next-gen wool
microbial factories are also capable of producing (e.g., OSOMbrand). Although these materials
proteins such as keratin, which forms the hair still originate from fossil fuels, their reuse in a
structure of fur, wool, and cashmere, as well as recycled format improves the circularity of the
sustainable biopolymers that replace synthetic material inputs and provides a new life for
polymer components (e.g., polyester, polyurethane) plastic waste, avoiding the use of virgin
for next-gen materials. petrochemicals.
Both the cultured animal cells approach and the Blends are those materials without a single
microbe-derived approach are forms of cellular component comprising more than 50% of the input
agriculture. The former produces cellular products, or those with no component over 50% that can be
where the output consists of the cells in the form attributed to one of the above categories.
of tissue constructs, while the latter produces
acellular products, i.e., the target molecules In all main input categories listed above,
absent the cells themselves. petrochemical derivatives may be present in the
form of binders, coatings, or fibers. While MII
In addition to the biologically derived materials practices “progress over perfection” as a means
listed above, recycled materials can also be to innovation, the next-gen ecosystem is tasked
employed as sustainable components in next-gen with an enormous white space opportunity to
materials. Plastic water bottles or textiles can be completely eliminate the use of petrochemicals in
collected and reprocessed into a variety of forms, their material formulations.
Hugo Boss shoes made with Piñatex® by Ananas Anam

PART B:
KEY STAKEHOLDERS
OR “THE THREE I’S”

4. INNOVATORS
OVERVIEW
This section provides an overview of companies in These companies employ a variety of input and
the next-gen materials industry. technology to create materials that range from
mats to fibers to insulating fluff. Some technologies
The lists focus on material innovators and are not allow a company to achieve diverse biomimicry and
exhaustive. Not included are business-to-customer applications. In the cases where a company has
companies that do not develop and create their plans to develop more than one type of next-gen
own materials, but source instead from a material material, the company will only be listed if that
supplier; R&D happening within corporations that product is at least in R&D.
is not publicly disclosed; startups in stealth mode;
and any other material innovations that do not The next-gen materials industry and the innovative
fall within the definition of next-gen materials as companies within this ecosystem develop at a fast
defined in section 2 Definition and Scope. pace, as can be seen in Figure 4.3 showing the
year-on-year number of new companies formed. All
Of the 74 companies, the clear majority (49) focuses company references are purely illustrative. Please
on biomimicry of animal leather. Nine (9) focus on check our website (https://www.materialinnovation.
biomimicry of silk, seven (7) on wool, five (5) on fur, org/) for the latest company information.
six (6) on down, and one (1) on exotic skins.*
*Some companies work on more than one
replacement of animal-based materials.
Table 4.1 Next-gen material companies (in alphabetical order)
Company name Material name HQ Founders Year Biomimicry Main Input

(if different from founded
company name)
Amadou Leather - GBR Irene Marie Seelig 2016 Leather Plant-derived
AMSilk Biosteel® (fibers & DEU Thomas Scheibel 2008 Silk Microbe-derived
finishing)
Ananas Anam Piñatex® GBR Dr. Carmen Hijosa 2011 Leather Plant-derived
Articor Cork - ESP Unavailable 1986 Leather Plant-derived

Products
Barktex - DEU Mary Barongo, Oliver 1999 Leather Plant-derived

Heintz
Beyond Leather Leap™ DNK Hannah Michaud, 2016 Leather Plant-derived

Mikael Eydt

company name)
Bio2Materials - POL Katarzyna 2018 Leather Plant-derived

Szpicmacher,
Aleksandra Kantor,
Prof. Artur Bartkowiak
Biophilica Treekind™ GBR Mira Nameth 2019 Leather Plant-derived
Biotecam Texticel BRA Ricardo Remer, Wim 2012 Leather Microbe-derived

Degrave
Bolt Threads Mylo™, Microsilk™ USA Dan Widmaier, David 2009 Leather, Silk Mycelium,
Breslauer, Ethan Mirsky Microbe-derived
Bucha Bio Bucha Leather USA Zimri T. Hinshaw 2019 Leather Microbe-derived
C-Combinator - PRI Geoff Chapin 2020 Leather Plant-derived
Coronet Spa Coronet BioVeg, Enrico De Marco 1966 Leather Blend

Coronet Maison,
ITA
Coronet
Innovaction
Culthread - Rina Einy 2018 Fur Recycled

GBR
material
Desserto - MEX Adrián López Velarde, 2019 Leather Plant-derived

Marte Cázarez
Devo Home - UKR Oksana Devoe 2008 Fur Plant-derived
Ecopel KOBA® Faux fur CHN Christopher Sarfati 2003 Fur Blend
EcoSimple - BRA Cláudio Rocha, Marisa 2010 Wool Recycled

Ferragutt material
EcoSupreme - USA Ivan Wang 2008 Down Plant-derived
Ecovative Design MycoFlex™, USA Gavin McIntyre, 2007 Leather Mycelium

Forager™ Hides Eben Bayer
ENKA - DEU Parent Company: 1924 Silk Plant-derived

International Chemical
Investors Group
Faborg Weganool™ IND Shankar 2015 Wool Plant-derived

Dhakshinamoorthy
Faircraft - FRA Haïkel Balti, Cesar 2021 Leather Cultured animal

Valencia-Gallardo cells
Fiquetex - COL Alejandro Moreno, 2017 Leather Plant-derived

Gabriel Moreno
Flocus - NLD Jeroen Muijsers 2014 Down Plant-derived
Flora Fur - USA Isabella Bruski, Noah 2018 Wool Plant-derived

Silva
Fruitleather - NLD Koen Meerkerk, Hugo 2016 Leather Plant-derived

Rotterdam de Boon
Frumat AppleSkin™ ITA Hannes Parth 2008 Leather Plant-derived
Grado Zero Muskin, BioGreen ITA Giada Dammacco, 2001 Leather, Down Plant-derived
Padding Filippo Pagliai
Gunas New York Mulbtex™ USA Sugandh G. Agrawal 2009 Leather Plant-derived
House of Fluff BIOFUR™ USA Kym Canter 2017 Fur Blend

company name)
Ipeker - TUR Gaffarzade Mehmet 1930 Silk Plant-derived

Efendi
Karu Tilex ARG Verónica Bergottini 2019 Leather Microbe-derived
KD New York Vegetable USA David Lee, Tricia Kaye 1980 Wool Plant-derived
Cashmere™
Le Qara - PER Jacqueline L. Cruz, 2017 Leather Microbe-derived

Isemar Cruz
Lignopure Lignoleather DEU Joana Gil Chavez, 2019 Leather Plant-derived

Wienke Reynolds,
Stefan Boersting
MakeGrowLab Transleather POL Roza Janusz, Josh 2016 Leather Microbe-derived

Brito
Malai - IND Zuzana Gombošová, 2018 Leather Microbe-derived

Susmith C S
Modern Meadow Zoa™ USA Andras Forgacs, Gabor 2011 Leather Microbe-derived
Forgacs, Karoly Jakab,
Francoise Marga
Mogu - ITA Maurizio Montalti, 2015 Leather Mycelium

Stefano Babbini,
Federico Maria Grati
MYCL (Mycotech Mylea™ IDN Annisa Wibi, Adi Reza 2015 Leather Mycelium
Lab) Nugroho, Ronaldiaz
Hartantyo, Arekha
Bentangan, Robby
Zidna Ilman
MycoWorks Reishi™ USA Philip Ross, Sophia 2013 Leather Mycelium

Wang, Eddie Pavlu
Mylium - NLD Iris Houthoff 2018 Leather Mycelium
Natural Fiber Mirum® USA Luke Haverhals 2015 Leather Plant-derived

Welding
Neffa MycoTEX® NLD Aniela Hoitink 2016 Leather Mycelium
Newlight AirCarbon™ USA Kenton Kimmel, Mark 2003 Leather Microbe-derived

Herrema
Nova Kaeru beLEAF™ BRA Eduardo Filgueiras 2006 Leather Plant-derived
Nuvi Nomad Teak Leaf Leather THA Nina Rössler 2014 Leather Plant-derived
Oleago Oleatex™ TUR Eşref Açık, Recep 2021 Leather Plant-derived

Eroğlu, Emre Eroğlu
Ono Cork Tencel Fabric CHE Bernadette Christina 2017 Leather Plant-derived
Collaborations Bodenmueller
Orange Fiber - ITA Enrica Arena, Adriana 2014 Silk Plant-derived

Santanocito
OSOMbrand OSOMtex® USA Patricia Ermecheo 2016 Wool Recycled

material
Panama Viridis® ITA Giuliano Pinato 1981 Leather Plant-derived

Trimmings

company name)
Pangaia FLWRDWN™ GBR Miroslava Duma, 2018 Down Plant-derived

Jasmine Mullers,
Rachna Bhasin,
Nathalie Longuet
Phool.co Fleather IND Ankit Agarwal 2017 Leather Microbe-derived
Pretty Simple - VNM Suong Hoang 2016 Leather Plant-derived
Primaloft - USA Unavailable 1983 Down Recycled

material
Provenance - USA Michalyn Andrews, 2016 Leather Microbe-derived

Biofabrics Christian Ewton
Proyecto Menos Bambuflex© ARG Natalia Pérez 2010 Leather Plant-derived

es Más
Qorium - NLD Rutger Ploem, Stef 2015 Leather Cultured animal

Kranendijk cells
Save The Duck Plumtech® ITA Nicolas Bargi 2012 Down Recycled
material
Seevix Material SVX™ Spidersilk ISR Shlomzion Shen, 2014 Silk Microbe-derived
Sciences Shmulik Ittah
Seringueira - BRA Wilson Antônio 2016 Leather Plant-derived

Manzoni
SmartFiber AG SeaCell™ GBR Subsidiary of Lenzing 2005 Silk Plant-derived

AG
Spiber Brewed Protein™ JPN Kazuhide Sekiyama, 2007 Silk Microbe-derived

Sugawara Junichi
Spidey Tek - USA Roberto Velozzi 2015 Silk Plant-derived
Spinnova - FIN Juha Salmela 2014 Wool Plant-derived
Studio Tjeerd Palmleather NLD Tjeerd Veenhoven 2000 Leather Plant-derived

Veenhoven
Tenbro - CHN Unavailable 2002 Wool Plant-derived
Ultrafabrics Ultraleather® USA Clay Andrew 1966 Leather Blend

Volar Bio Rosenberg, Barbara
Danielle Boecker-
Primack
Unreal Fur - AUS 2011 Fur Recycled

material
Vegea - ITA Francesco Merlino, 2016 Leather Plant-derived

Valentina Longobardo
VitroLabs - GBR Ingvar Helgason 2016 Leather, Exotic Cultured animal
Skins cells
Von Holzhausen Technik Leather, USA Vicki von Holzhausen 2015 Leather Plant-derived
Banbū Leather
Have we missed anything? Please let us know through this form.

Table 4.2 Material manufacturers that have next-gen materials in their offerings
Company Name Material Name Headquarters Biomimicry Main Input
3M Thinsulate TM
Insulation - Featherless USA Down Recycled material
Fiscatech E-ULTRA® ITA Leather Plant-derived
General Silicones Compo-SiL® TWN Leather Blend
ISA TanTec COSM™ HyphaLite, COSM™ VeraLite MAC Leather Plant-derived
Jord Suberhide™ USA Leather Plant-derived
Lenzing Tencel™ AUT Silk Plant-derived
Thermore Ecodown® NLD Down Recycled material
Toray Industries Ultrasuede® JPN Leather Blend
TREND
Of the 74 companies innovating in next-gen In 2016 alone, 10 new companies were formed
materials, 42 were established since 2014. to create next-gen leather. Plants or plant-
Most (30) of these 42 new companies focus on derived materials have historically been the
leather biomimicry. In the same period, three (3) main input for leather alternatives, but recently
companies were formed that focus on biomimicry more new companies are using mycelium
of silk, four (4) on wool, two (2) on fur, two (2) down, and microbe-derived materials to create their
and one (1) on both leather and exotic skins. next-gen leather.
Figure 4.3 Number of companies growth trend
80 72
74
Number of companies formed
71
66 Total companies
70
60
60 55
Year Leather Silk Wool Fur Down Exotic

50 44
Skins
2014 1 2 1 - 1
40 37 2015 5 1 1 - -
2016 10 - 1 - - 1*
11
2017 4 - - 1 -
10
7 6 2018 3 - 1 1 1
5 5 5 2019 5 - - - - -
1 2 2020 1 - - - - -
2021 (up to April 30) 2 - - - - -

0
2014 2015 2016 2017 2018 2019 2020 2021
(up to
April 30)
*VitroLabs creates both leather and exotic skins and is thus counted as “1” under leather and “1” under exotic skin,
but is NOT counted twice under “Number of companies formed” and “Total number of companies.”

INSIDER INSIGHTS
In 2020, successful collaborations between grape (by Vegea), mango (by Fruitleather
next-gen material companies and industry Rotterdam), and apple (by Frumat), many different
brands (see section 1 Introduction) have made technologies and inputs are part of reimagining
headlines in fashion news. Although next-gen next-gen materials. The following aims to shed
materials are commonly associated with leather light on the spectrum of offerings across
made from plants, for example: pineapple different material categories by companies
(Piñatex® by Ananas Anam), cactus (by Desserto), around the world.
IN
“Spiber is essentially growing protein
Spiber Inc. is a Japanese biotechnology company developing synthetic
(polymers), which can potentially
spider silk without the use of animals or petroleum resources. be used in a very wide variety
of applications. Using precision
fermentation, Spiber has the ability
to create bespoke proteins that may
enable suites of next-gen materials
to outperform current natural and
synthetic fibers. Spiber has told us that
while they are now focusing on silk and
cashmere-like materials, because of
the versatility of Brewed Protein™, they
are also exploring other applications
such as next-gen leather and fur
alternatives. Importantly, Spiber has
overcome the industry-wide challenge
Tech: Brewed Protein™ is the company’s sustainable material inspired by spider to process their raw protein into a
silk and produced via its proprietary fermentation process. First, the code for robust fiber that can then be spun
the desired protein is inserted into microorganisms. Using the necessary sugars into yarn (wool-like, cashmere-like)
or filament (silk-like) and woven or
and minerals, these microorganisms grow the desired protein in a bioreactor.
knitted into fabric, or processed into
After fermentation is complete, the protein is purified and dried into a pellet or other forms, such as non-woven,
powder. Brewed Protein can then be processed into a variety of materials, e.g. fur-like, hair-like materials.”
fibers with a silky sheen, spun into yarns with cashmere- or wool-like properties.
Scale: The company is currently

constructing the world’s largest
structural protein fermentation
facility in Thailand. With this
expansion, Spiber aims to
manufacture sustainable protein-
based materials at a competitive
cost. Commercial production of - Dr. Sydney Gladman,
Brewed Protein polymer is expected Chief Science Officer of MII
to begin in the later half of 2021,
with a production capacity of several
hundred tons per year.

IN
PANGAIA is a UK materials science and lifestyle products company. The “What I found most interesting is
company aims to solve environmental problems through the development of Pangaia’s business model. From the
outside, Pangaia looks like a direct-
sustainable materials, treatments, and dyes in partnerships with researchers
to-consumer company that has built
in Europe, Japan, Korea, and the United States. One of its material creations a successful brand in a short period
is FLWRDWN™, a plant-based and petroleum-free alternative to duck and of time. But Pangaia plays multiple
roles in the supply chain: in addition to
goose down.
selling its own design as a fashion and
apparel brand (D2C), it’s also a material
innovator that creates materials like
FLWRDWN™ and supplies them to
other brands (B2B). And Pangaia is
a buyer as well, sourcing from other
material innovators to create its design
(its grape leather sneakers are one
example.) The company told us that its
growth mainly happened during 2020,
and that it now has a 125-member
team. It’s even more exciting to learn
that Pangaia has plans to expand into
other verticals like food and skincare.
The multifaceted positioning of
Tech: Using PANGAIA’s proprietary technology, FLWRDWN™ is a biopolymer Pangaia may prove to be a
created from flowers and infused with a cellulose-based aerogel for increased competitive edge.”
durability, thermal insulation, and water resistance. It is the first time that
this kind of flower has been used in a loose-fill insulation. The material is fully
biodegradable, hypoallergenic, and animal-free. FLWRDWN™ has been in
development by the PANGAIA’s Italian scientists for over 10 years and the patent
covers the production method of the flower, biopolymer, and aerogel to create
FLWRDWN™.
Scale: The company’s brand strategy

is not limited to apparel and PANGAIA
is currently exploring innovations
- Elaine
Siu, Chief Innovation
in the skincare and food space. The
Officer of MII
goal of the brand is to improve access
to sustainable materials and drive
their adoption on a global scale. To
achieve this, B2B is crucial and will
take different forms at PANGAIA,
including sharing its innovations at
material stage, and through white
label manufacturing and corporate
gifting programs.

IN
Natural Fiber Welding, Inc. (NFW) is a material technology platform company “Their products seem significantly
bringing to market new manufacturing routes and material chemistry that alter customizable. We examined their
entire swatch book, which contains a
how plant-based materials perform in products. One of its material creations
variety of colors, thicknesses, finishes,
is MIRUM®, a plant-based leather that uses no petroleum-based plastics like and backings. In talking with NFW,
polyurethane or PVC. what stood out to me was that their
technology platforms can produce not
only flat leather-like materials, but also
cured rubber that can be formed and
shaped in multiple dimensions. This
means that NFW could produce all
of the components of a shoe from its
materials, which are all bio-based
with zero plastics. This is extremely
desirable from a life-cycle and end-
of-life perspective, enabling true
circularity and new ways to think
about recycling products.”
Tech: The chief technology of the platform is based on a patented plant-based

curative and process to cure natural rubber and create high performance, all-
natural leather like materials. This enables the creation of all natural composites
that use a diverse set of natural fillers and fibers (cork shavings, rice hulls, and
coconut fibers, among others) that deliver the performance, sustainability, and
aesthetic needs for fashion, footwear, upholstery, and automotive industries.
The platform delivers tunable final performance properties (rigidity, suppleness,
elasticity, tensile strength, etc.) based on the raw material components as well
-T
homasine Dolan, Fashion
as variations in the manufacturing process conditions. The resulting material
Design Specialist of MII
can deliver a broad set of grains and finishes, from leather like to geometric or
nature-inspired looks and feel.
Scale: In February 2021, NFW announced plans to open a new 110,000-square-

foot manufacturing space for production of MIRUM®. This expansion will more
than double the company’s existing manufacturing capacity. The company
plans to eventually produce tens of millions of square feet of MIRUM® per year
for global brand partners.

IN
VitroLabs is a tissue-engineering platform company growing calf hides from “No matter how advanced biomimicry
animal cells, eliminating any need to raise or slaughter animals. techniques may become, some people
will continue to only want the ‘real
thing.’ This is the case for meat, and it
will be for leather. Therefore, at least
part of the solution to the dilemma
of balancing consumer demand
and harm to the environment and
animals ought to be to revolutionize
the production method. There is
nothing inherently wrong with the
end product, be it meat or leather. We
need to fix how they are produced.
Why are we raising a live animal as the
production unit of the end product,
creating all the negative impact to
environment and welfare, as well as
Tech: VitroLabs is producing real calf leather through tissue engineering, also
depleting natural resources, when
known as cultivated leather. The cultivation process starts with a one-time small the production unit can be a
sample of cells from an animal. The cells are then placed within a proprietary bioreactor instead?
bioreactor. The bioreactor facilitates the natural growth process by providing a

Cultivated meat research is taking
nutrient-rich environment in which the cells can grow. Within this environment, place in hundreds of companies and
the cells make collagen and other key proteins that make up the cow hide. academic laboratories around the
Cultivated hides have the same cellular composition of traditional hides used world, in order to create meat products
at industrial scale. We are already
in traditional leather. VitroLabs hides can be grown in just a few weeks, instead
seeing the early signs of this in the
of the 2-3 years it takes to rear an animal, and can be tanned with significantly materials space. I’ve seen first hand
fewer chemicals and a reduced tanning process. Cultivating animal hides to how quickly change can happen.
make real leather provides the positive qualities: look, smell, durability, etc. of Promoting cultivated meat research to
the Singapore government agencies
traditional cow leather, without the negative impact on animal welfare and
as a novel food production method,
the environment. announcing the world’s first regulatory
approval for cultivated meat sale, and
then the general public being able to
eat cultivated meat in a restaurant - all
of this happened within 3 years. That
gives me confidence we will also see
tissue engineering revolutionize
the material space.”
- Elaine Siu, Chief Innovation

Officer of MII
Scale: Moving from R&D to pilot scale.

5. INVESTORS
OVERVIEW
This section provides an overview of the investment Silk Dress by Bolt Threads for Stella McCartney
activities in the next-gen materials industry.
The data collected and analyses conducted

are based solely on MII’s list of companies in
table 4.1. The list of investors, investment figures,
and other data are severely limited by publicly
disclosed information. Academic funding, corporate
R&D investment, and other undisclosed deals are
not included.
The investment figures presented in this section,

whether in relation to the industry or to each individual
company or investor, are therefore likely underestimated.
Beyond the information in this section, many investors

are evaluating deals, but have not yet completed their
first investment in this space. MII expects the list of
investors to look very different in our next State of the
Industry Report. All investment, investor, and company
references are purely illustrative.
IN
Investors on the panel at the Rethinking

Materials 2021 conference were asked whether
2021 will be a down year, average year, or an
exceptional year for innovation and deal making
in sustainable materials.
On a scale of 1-10, with 10 being most exceptional,

all panelists unanimously said it will be an 11.

Table 5.1 Investors in next-gen material companies by deal count
The following is a list of investors in the next-gen material companies listed in table 4.1,
in descending order by number of investments. Only publicly disclosed information is included.
Investor Number of Number of Companies Investor Type Headquarters

Investments Companies
Invested In
Horizons Ventures 4 1 Modern Meadow Venture Capital Hong Kong
SOSV 4 2 Bucha Bio, MycoWorks Accelerator, Micro VC, New Jersey, USA
Venture Capital
Formation 8 3 1 Bolt Threads Venture Capital California, USA
Foundation 3 1 Bolt Threads Venture Capital California, USA

Capital
IndieBio 3 1 MycoWorks Accelerator California, USA
MUFG Bank 3 1 Spiber Investment Bank, Tokyo, Japan

Venture Capital
Novo Holdings 3 2 AMSilk, MycoWorks Venture Capital Hellerup, Denmark
Rockstart 3 1 Beyond Leather Accelerator, Venture Noord-Holland, The

Capital Netherlands
8VC 2 1 MycoWorks Venture Capital California, USA
AgFunder 2 1 Modern Meadow Venture Capital California, USA
Alafi Capital 2 1 Bolt Threads Venture Capital California, USA
Archer Daniels 2 1 Spiber Corporation Illinois, USA

Midland Company
(ADM)
Artis Ventures 2 1 Modern Meadow Venture Capital California, USA

(AV)
Collaborative 2 1 Modern Meadow Micro VC New York, USA

Fund
DCVC Bio 2 1 MycoWorks Venture Capital California, USA
East West Capital 2 1 Bolt Threads Venture Capital Sydney, Australia

Limited
Founders Fund 2 1 Bolt Threads Venture Capital California, USA
ICONIQ Capital 2 1 Modern Meadow Family Investment California, USA

Office, Private Equity
Firm, Venture Capital
Mission Bay 2 1 Bolt Threads Venture Capital California, USA

Capital
Ralph Lauren 2 1 Natural Fiber Welding Corporation New York, USA

Corporation
Red Swan 2 1 Modern Meadow Venture Capital New York, USA

Ventures
Shonai Bank 2 1 Spiber Bank Tsuruoka, Japan
Susa Ventures 2 1 MycoWorks Micro VC, Venture California, USA

Capital
Temasek Holdings 2 2 Bolt Threads, Modern Private Equity Firm Singapore

Meadow
Tony Fadell 2 2 Modern Meadow, Investment Partner, Paris, France

MycoWorks Individual/Angel

Invested In
Zygote Ventures 2 1 Bolt Threads Angel Group California, USA
3M 1 1 Ecovative Design Corporation Minnesota, USA
3M New Ventures 1 1 Ecovative Design Venture Capital Minnesota, USA
Activate Venture 1 1 Modern Meadow Micro VC New York, USA

Partners
Allbirds 1 1 Natural Fiber Welding Corporation California, USA
Allen & Company 1 1 Bolt Threads Family Investment New York, USA
Office, Investment
Bank, Venture Capital
Alpha Impact 1 1 Ecovative Design Private Equity Firm, California, USA

Investment Venture Capital
Management
Partners
Astanor Ventures 1 1 Modern Meadow Venture Capital Brussels, Belgium
Athos Group 1 1 AMSilk Corporation Texas, USA
Avant Global 1 1 Modern Meadow Venture Capital California, USA
Baillie Gifford 1 1 Bolt Threads Investment Bank, Edinburgh, UK

Venture Capital
Black Point Group 1 1 Modern Meadow Venture Capital Maine, USA
Breakout Labs 1 1 Modern Meadow Micro VC California, USA
Breakout 1 1 Modern Meadow Micro VC California, USA

Ventures
Business Finland 1 1 Spinnova Government Office, Helsinki, Finland

Venture Capital
Cape Capital AG 1 1 Modern Meadow Private Equity Zurich, Switzerland
Cargill 1 1 AMSilk Corporation Minnesota, USA
Central Illinois 1 1 Natural Fiber Welding Angel Group Illinois, USA

Angels
Continental Grain 1 1 Modern Meadow Corporate Venture New York, USA

Company Capital
Cool Japan Fund 1 1 Spiber Government Office, Tokyo, Japan

Venture Capital
Cthulhu Ventures 1 1 MycoWorks Micro VC, Venture California, USA

Capital
Dai-ichi Life 1 1 Spiber Investment Bank, Tokyo, Japan

Venture Capital
Dave Eisenberg 1 1 Modern Meadow Investment Partner, New York, USA

Individual/Angel
DOEN 1 1 Ecovative Design Venture Capital Amsterdam, The

Participaties Netherlands
E.R. Capital 1 1 AMSilk Private Equity N/A

Holdings
Ebara Corporation 1 1 Spiber Corporation Tokyo, Japan
Enmi Kendall 1 1 Modern Meadow Investment Partner, California, USA

Individual/Angel

Invested In
Eudaimonia 1 1 Modern Meadow Angel Group, Family Singapore

Capital Investment Office
European 1 1 Spinnova Government Office, Luxembourg

Investment Bank Investment Bank
Evonik Venture 1 1 Modern Meadow Corporate Venture Hanau, Germany

Capital Capital, Venture Capital
Fidelity 1 1 Bolt Threads Private Equity Massachusetts, USA

Management &
Research
Francois Kress 1 1 Modern Meadow Individual/Angel New York, USA
Francoise Marga 1 1 Modern Meadow Individual/Angel New York, USA
Future Tech Lab 1 1 MycoWorks Venture Capital Stockholm, Sweden
Hatzimemos/ 1 1 Modern Meadow Venture Capital New York, USA

Libby
Humboldt Fund 1 1 MycoWorks Venture Capital New York, USA
Indian Angel 1 1 Kanpur Flowercycling Angel Group Delhi, India

Network Private Limited
Innovation 1 1 Bolt Threads Venture Capital California, USA

Endeavors
Interplay Ventures 1 1 Modern Meadow Venture Capital New York, USA
John Legend 1 1 MycoWorks Individual/Angel Nevada, USA
Karoly Jakab 1 1 Modern Meadow Individual/Angel New York, USA
Key Partners 1 1 Modern Meadow Investment Partner Berlin, Germany

Capital
Lee Barba 1 1 Modern Meadow Individual/Angel New York, USA
LeFrak 1 1 Bolt Threads Venture Capital New York, USA
MassChallenge 1 1 Orange Fiber Accelerator Massachusetts, USA
MIG 1 1 AMSilk Venture Capital Munich, Germany
Mission BioCapital 1 1 Bolt Threads Venture Capital Massachusetts, USA

company
Mitsubishi UFJ 1 1 Spiber Corporation Tokyo, Japan

Lease and Finance
Nan Fung 1 1 Bolt Threads Private Equity Hong Kong
Natalie Portman 1 1 MycoWorks Individual/Angel N/A
Prairie Crest 1 1 Natural Fiber Welding Venture Capital Iowa, USA

Capital
Senator 1 1 Ecovative Design Hedge Fund New York, USA

Investment Group
Sequoia Capital 1 1 Modern Meadow Venture Capital California, USA
Silicon Valley 1 1 Bolt Threads Investment Bank California, USA

Bank

Invested In
Singularity 1 1 Modern Meadow Venture Capital California, USA

University
Ventures
Starlight Ventures 1 1 Modern Meadow Venture Capital Florida, USA
Steen Ulf Jensen 1 1 Beyond Leather Individual/Angel Copenhagen, Denmark
The Draper 1 1 Kanpur Flowercycling Micro VC, Venture California, USA

Richards Kaplan Private Limited Capital
Foundation
The Yamagata 1 1 Spiber Bank Yamagata, Japan

Bank
Toyoshima 1 1 Spiber Corporation Nagoya, Japan
Toyota Boshoku 1 1 Spiber Corporation Kentucky, USA

America
Trousdale 1 1 Ecovative Design Venture Capital Texas, USA

Ventures
TSURUOKA 1 1 Spiber Bank Yamagata, Japan

SHINKIN BANK
Ulu Ventures 1 1 Modern Meadow Micro VC, Venture California, USA

Capital
Vaekstfonden 1 1 Beyond Leather State Investment Fund Hellerup, Denmark
Valor Equity 1 1 MycoWorks Private Equity, Venture Illinois, USA

Partners Capital
VF Ventures 1 1 Beyond Leather Venture Capital Hellerup, Denmark
Viking Global 1 1 Ecovative Design Private Equity Connecticut, USA

Investors
Wireframe 1 1 MycoWorks Venture Capital California, USA

Ventures
WTT Investment 1 1 MycoWorks Venture Capital Taipei, Taiwan
Source: MII analysis on investment activities in companies in MII’s company database,

based on data from SPEEDA Edge, as well as primary and secondary research.
Have we missed anything? Are you an investor interested in the next-gen material industry?
Please contact us via this form.

Eva Klabalová & Lucie Trejtnarová sandals made with Malai leather
CAPITAL
Investment in next-gen material innovation By mid-May 2021, 4 of the top 10 funded companies
reached new heights in 2020. The investment have successfully raised new rounds. Investment
amount in the year of 2020 alone is nearly the is expected to further increase as companies
same as the previous 4 years combined. Even mature, demonstrate proof of concept,
amid the Covid-19 pandemic, this trend continued. and scale.
Figure 5.2 Total venture capital invested in next-gen material companies
600 8
Million USD Invested
Number of deals
7
500
6
400
5
300 4
3
200
2
100
1
0 0
2015 2016 2017 2018 2019 2020 2021
(up to
May 14, 2021)

COMPANIES
The following are the 10 most funded among the next-gen material companies listed in table 4.1
according to publicly disclosed data.
Table 5.3 Top 10 most funded next-gen material companies (in descending order by total amount raised)
Company Brief Company Description Largest round Total amount raised

(Million USD) / date (Million USD) / round
Spiber Produces spider silk proteins via precision fermentation 292.9 / Dec 2020 598.8 / Series
to create next-gen silk primarily for the fashion industry. Unknown
Collaboration with the designer Yuima Nakazato, The
North Face Japan, Goldwin, Toyota.
Bolt Threads Grows mycelium to produce next-gen leather and uses 123 / Nov 2017 218.1 / Series D
precision fermentation to produce spider silk proteins for
next-gen silk. Both primarily target the fashion industry.
Collaboration with Adidas, Kering, Lululemon, Stella
McCartney.
Modern Meadow* Uses precision fermentation to grow collagen to create 130 / Apr 2021 183.5 / Series C
animal-free leather primarily for the fashion industry.
Newlight* Uses natural ocean microorganisms to make PHB from 45.1 / Sep 2020 106.6 / Series F
greenhouse gasses to produce next-gen leather primarily
for the fashion industry.
Ecovative Design Grows mycelium on agricultural waste to produce 60 / Mar 2021 90.1 / Series D
next-gen leather, primarily for the fashion and self-care
industries.
MycoWorks* Grows mycelium to produce next-gen leather primarily 45 / Oct 2020 62.0 / Series B
for the fashion industry. Collaboration with Hermès.
AMSilk* Makes spider silk proteins via precision fermentation to 36 / May 2021 42.3 / Series C
produce next-gen silk primarily for the fashion industry.
Spinnova Uses FSC-certified wood and waste streams to produce 12.3 / Oct 2019 20.7 / Venture Capital
next-gen wool primarily for the fashion industry.
Collaboration with Marimekko, H&M, Bergans of Norway,
Bestseller (Fashion FWD).
Natural Fiber Uses fabricated compressed and/or discarded fiber 13 / Aug 2020 15.0 / Venture Capital
Welding sources coated with plant-based oil resin to produce
next-gen leather primarily for the fashion industry.
Collaboration with Richemont, Steelcase.
Save The Duck Uses recycled PET bottles to produce next-gen 3.6 / Mar 2021 3.6 / Debt
down primarily for the fashion industry. Collaboration
with Dyne.
*Company with one or more rounds of undisclosed amount. Undisclosed amounts are not reflected in the total amount raised in this table.
Source: MII analysis on investment activities in companies in MII’s company database, based on data from SPEEDA Edge, primary and secondary research.

Figure 5.4 Funding history of top 10 funded next-gen material companies
600 Spiber
500
400
USD million
300
Modern Meadow*
200
Bolt Threads
Newlight*
100 Ecovative Design
MycoWorks*
AMSilk*
Spinnova
Natural Fiber Welding
0 Save The Duck
Prior 2015 2016 2017 2018 2019 2020 2021
to (up to 18
2015 May 2021)
*Company with one or more rounds of funding with undisclosed amounts. Undisclosed amounts have not been reflected in this figure.
Source: MII analysis on investment activities in companies in MII’s company database, based on data from SPEEDA Edge, primary and secondary research.
The North Face Moon Parka by Spiber

INSIDER INSIGHTS IN
Unlike others in the top 10 funded list, Bolt Threads did not raise most of its These are some of the
funds in the last few years. Its series D round was closed in 2017. reasons venture capitalists
are excited about the
Bolt Threads, originally named Refactored Materials, was founded in 2009 by prospects of Bolt Threads:
Dan Widmaier, David Breslauer, and Ethan Mirsky to use biotechnological
innovation to create materials. Dan Widmaier initially developed this idea “The company has now become more
of a tech platform with a portfolio
during his Ph.D. in Chemical Biology. The company has since grown
of products rather than just a
to a team of nearly 100 employees. single material.”
“True full loop capabilities from

The company’s first material is their spider silk product Microsilk. They then
sourcing and manufacturing to
expanded into making alternative leather from mycelium. Transformation commercialization and branding.”
takes time. According to Dan Widmaier, Bolt Threads went through
4,000 material sample iterations. “Overall the team has done well in
raising capital from both renowned
industry & financial investors and
having short-term quick wins like
product & consortium launches, while
waiting for the tech to scale in the
longer term.”
“...chose to partner with the most

exciting luxury and premium brands
on the planet to validate potential.”
“...focus on aesthetics and

performance. Goal is to make brands
and consumer journey seamless
and frictionless... best analogs are
Impossible Foods and Tesla. Bolt is
that solution for materials.”
Partner also mentioned:
“The founding team has done a lot

in giving back to the ecosystem and
industry, such as mentoring/advising
new material founders, as well as
offering residencies for graduate
students/scientists. The next step
for the company is in scaling up
production & supply of materials for
larger commercialization.”

The largest funding round in 2021 to date (May 2021) is the $35 million
series C investment in AMSilk. Novo Growth, the growth equity arm of
Novo Holdings, led the round. Kartik Dharmadhikari and Anders Bendsen
Spohr, partner and senior partner, respectively, at Novo Holdings, will join
AMSilk’s supervisory board.
Novo Holdings has also invested in MycoWorks, a mycelium-based alternative

leather company.
Dharmadhikari explained what makes AMSilk stand out, “AMSilk’s technology

has the potential to revolutionize a number of industries and be part of
the decarbonization push needed to overcome the biggest environmental
challenges of our time.”
AMSilk is said to be the world’s first industrial supplier of synthetic silk

biopolymers. The financing will help the company expand into new markets.
The silk biopolymers are suitable for high performance sports apparel and
biomedical applications, including medical implants. The materials can be
fully recycled and are 100 percent biodegradable. AMSilk offers its innovative
range of high performance Biosteel fibers for textiles and industrial applications
worldwide and has announced collaborations and partnerships with world
leading brands like Adidas and Airbus. The organic high performance material
has multiple applications.

6. INDUSTRY BRANDS
OVERVIEW
Industry brands are the established companies next-gen materials as their raw materials, and
that are the biggest buyers and users of materials. collaborating with next-gen material startups to
While consumer preference has driven industries to create new products. All this leads to acceleration
move towards more sustainable practices, material of commercialisation and scale-up production of
innovators seldom have a direct relationship with next-gen materials to replace their conventional
the end consumers. The success of transitioning counterparts.
from animal-based materials to next-gen materials
largely depends on the innovators’ ability to work This section reviews fifteen representative brands
with industry brands. in the fashion, automotive, and home goods
industries to assess opportunities available to
Industry Brands can play multiple important roles material innovators.
in the ecosystem, including funding both internal
and external innovation initiatives, switching to
Table 6.1 Involvement of industry brands in material innovation
Brand Revenues (FY2020) Industry Animal-based Actions done with respect to material
Materials used innovation
Internal R&D Investment Partnership
Adidas approx. USD 24.1 Fashion Leather, Wool,

billion Silk, Down
aunched a shoe made from synthetic silk biopolymer Biosteel in partnership with AMSilk.
L
(November 2016)
ollaborated with Stella McCartney to create a tennis dress from spider silk developed by Bolt
C
Threads. (July 2019)
artnership with Parley to produce 15 million pairs of shoes using plastic waste from oceans,
P
representing approximately 4% of all pairs produced in 2020.
artnership with Bolt Threads to use the mycelium-based leather Mylo in a sneaker model. (April 2021)
P
lans to launch a plant-based shoe from using materials based on algae, eucalyptus trees, and natural
P
rubber. (April 2021)
artnered with Allbirds to produce an ultra-green shoe with 70% Adidas’s recycled primegreen
P
polyester and 30% natural Tencel, a material produced from wood pulp. (May 2021)
Nike USD 37.4 billion Fashion Leather, Wool,

Down
aunched the “Space Hippie” footwear collection with sneakers created from 85–90% recycled
L
polyester yarn and foam. (June 2020)
aunched the “Cosmic Unity” collection with a basketball shoe produced from 25% recycled material
L
and apparel collection with over 95% recycled and/or organic content. (February 2021)

H&M approx. USD 21.8 Fashion Leather, Wool,

billion Silk, Down
“Conscious Exclusive Collection” used Orange Fiber made from citrus juice by-products to create a
cellulose silk fabric, Piñatex pineapple leather, and BLOOM Foam, a flexible algae-based foam. (April
2019)
ollaboration with Vegea to use its leather made from grape wine waste to create handbags.
C
(February 2021)
artnered with sustainable footwear brand Good News to create footwear made from Bananatex, a
P
durable, waterproof material made with banana fibers. (April 2021)
Stella McCartney approx. USD 55.0 Fashion Wool, Silk,

million* Down
artnered with Bolt Threads to use its precision-fermented spider silk protein thread in apparel. (July
P
2017)
artnered with Aquafil to use Econyl regenerated nylon, made from waste fabrics and fishing nets, for
P
apparel and handbags. (June 2017)
sed KOBA bio-based fur, made from recycled polyester and plant-based plastic, to replace animal-
U
based fur. (October 2019)
eleased prototype bag (2018) and apparel (2021) from Mylo mycelium leather in partnership with Bolt
R
Threads.
sed Re.Verso, a recycled cashmere made from post-factory cashmere waste. (April 2017)
U
artnership with Evrnu and Adidas to use NuCycle, a material made from liquefied cotton waste. (July
P
2019)
Gap USD 13.8 billion Fashion Leather, Wool,

Silk, Down
AP’s activewear brand Athleta used sustainable fibers (including recycled polyester and nylon) in
G
60% of its materials as of 2019. The sportswear also included the material Econyl - a 100% regenerated
nylon fiber made from fishing nets - through partnership with Aquafil. (April 2019)
aunched the internally developed fabric H2Eco made from waste from landfills in swimwear
L
products under the brand Athleta. (April 2019)
PUMA approx. USD 6.3 Fashion Leather, Wool,

billion Silk, Down
artnered with First Mile to launch a sportswear collection using recycled plastic bottles. (March 2019)
P
pparel and shoe collections with recycled polyester and cotton from textile industry waste. (April
A
2021)
Patagonia approx. USD 800 Fashion Leather, Wool,

million* Silk, Down
artnership with Bolt Threads to create jackets from spider silk. (May 2016)
P
artnered with TENCEL to use lyocell fiber as an alternative to viscose rayon. (October 2016)
P
artnership with Bureo to develop NetPlus material from discarded fishing nets for use in hat brims,
P
sunglasses, surfboard fins. (July 2020)
aunched a jacket with PrimaLoft’s recycled polyester insulation. (March 2021)
L
Fossil USD 1.6 billion Fashion Leather
ier Tote bag from cactus leather in partnership with Desserto. (April 2021) Fossil plans to expand the
K
use of Desserto’s leather to its men’s collection to be released in fall 2021.
kagen brand watch straps from next-gen leather made from mulberry bark, cork, and apple; over
S
50% recycled materials in clock faces. (April 2021)

Ralph Lauren USD 6.2 billion Fashion Leather, Wool,

Silk, Down
inority investment in Natural Fiber Welding, a company that makes plant- and natural fiber-based
M
materials. (August 2020)
artnered with Aquafil to use Econyl material - made from consumer waste including fishing nets,
P
industrial plastic waste, and fabric scraps - in selected styles (2020).
se of recycled polyester made from fiber derived from waste plastic bottles in more than 100 styles.
U
(2020)
artnered with PrimaLoft to use its down alternative ThermoPlume, made from recycled plastic
P
bottles, as insulation for jackets. (October 2020)
BMW approx. USD 98.2 Leather, Wool

billion#
artnered with Aquafil to use Econyl material, made from recycled fishing nets and other nylon
P
waste, in headliners and floor mats of selected vehicle models. (February 2016)
Bentley approx. USD 2.5 Leather, Wool

billion
artnership with Vegea to use grape leather in car interiors. (July 2019)
P
Mercedes Benz approx. USD 119.5 Leather, Wool

billion#
artnered with Miko to use Dinamica microfiber, made from textiles and PET bottles, in the interior of
P
certain vehicle models. (January 2021)
artnered with Aquafil to use Econyl material, made from recycled fishing nets and other nylon
P
waste, in floor mats of vehicles. (October 2020)
Volkswagen approx. USD 270 Leather

billion
”AppleSkin” Apple leather developed in partnership with Apple Nine Alliance. (April 2019)
Ikea approx. USD 28.2 Home Leather, Wool,

billion goods Silk, Down
artnered with H&M group and Stora Enso to develop a new textile fiber based on cellulose from
P
wood. (December 2018)
Herman Miller USD 2.5 billion Home Leather, Wool

goods
oined the NextWave plastics initiative as a founding member to develop the first global network of
J
ocean-bound plastic supply chain. (2018)
Introduced a collection made from ocean-waste plastic and biodegradable polyester. Available as a
material for their seating products. (2021)
*Full year 2019 figures. #Part of the company’s business only.

Source: SPEEDA Edge

Many industry brands have specific, publicly disclosed targets and pledges to attain measurable
improvements in sustainability. These new targets create concrete opportunities for material innovators.
Table 6.2 Sustainability commitments from industry brands
Brand Current Sustainability Commitments Future Sustainability Commitments
Adidas Issued a sustainability bond of EUR 500 million Replace virgin polyester entirely with recycled
(USD 585 million) in Sep 2020 to be used for polyester by 2024.
investments into more sustainable materials and
processes.
1% of all polyester used for their apparel and
7
footwear was recycled polyester in 2020.
ore than 60% of all Adidas products will be
M
made from sustainable materials for the first time
in 2021.
Nike 8% of Nike, Jordan, and Converse shoes

7 Increasing the use of low-carbon materials to 50%
contained some amount of recycled materials as of all key materials (polyester, cotton, leather, and
of May 2021. rubber) by 2025.
roduces footwear from recycled polyester
P
from over 1 billion post-consumer plastic bottles
annually.
ses recycled and organic cotton (10% of total
U
cotton volume as of 2020) and recycled polyester
(26% of total polyester volume as of 2020).
9% sustainable materials used in Nike apparel as
5
of 2020.
9% sustainable materials used in Nike footwear
2
as of 2020.
H&M ecycled polyester from an equivalent of 1.1 billion

R Use 100% sustainable or recycled material to
PET bottles in 2020 (537 million in 2019). manufacture products by 2030.
4.5% of materials were recycled or sustainably
6
sourced in 2020.
ourcing of recycled materials more than
S
doubled to 5.8% of total materials in 2020 (from
2.2% in 2019).
Stella McCartney ince its founding, the company has never used
S No products contain animal-based leather,
animal-based materials such as leather, feathers, feathers, fur or exotic skin.
fur, and skin.
tarted using recycled polyester in 2012.
S
Gap - Gap's brand Banana Republic has a goal to make

50% of its products with sustainable fibers by 2023.
Puma - Develop recycled material options for leather,

rubber, cotton, and PU by 2025.
Over 50% sustainable material content in 90% of
PUMA Apparel and Accessories by 2025.
90% of all footwear to contain at least one
sustainable component by 2025.
Increase the use of recycled polyester in apparel
and accessories to 75% by 2025.

Brand Current Sustainability Commitments Future Sustainability Commitments
Patagonia Capilene Cool Tech t-shirt collection made from 35- Produce all apparel products from 100% recycled,
reclaimed or renewable resources by 2025.
100% recycled material; Baggies shorts collection
from 100% recycled nylon.
Fossil - Include sustainable design elements in over 50% of
products sold globally by 2025.
Ralph Lauren - Source 100% of key materials sustainably by 2025.
BMW In Feb 2021, BMW announced that its British car In Aug 2020, the company announced the switch to
brand MINI will stop offering leather interiors in all vegan leather in all new 5-series models.
new models by 2021.
Bentley - -
Mercedes Benz - -
Volkswagen - -
IKEA ecycled polyester used in 83% of home textile

R Use only renewable or recycled materials in
products in 2020 (~59% in 2019). products by 2030.
s of May 2021, 60% of materials are renewable
A
and 10% are recycled.
Herman Miller - -
Source: SPEEDA Edge
IN
“Globally, people are becoming more aware of the

impacts their everyday choices can have on the
environment. We’ve seen that small, thoughtful
decisions and initiatives can have big impacts and
the move toward animal-free fashion around the
world is one example of this.”
- Alyssa Whited, Global Director of Marketing,
Call It Spring

Natural Fiber Welding leather Mirum™ colored sheets
INSIDER INSIGHTS
A key takeaway from the Hanson-Wade/Material Innovation Initiative Bio-Based Alternative Textiles
Innovation Summit (March 31 & April 1, 2021) is the need for honesty and transparency from material
innovators with brands, consumers, and investors. With any new technology, time and patience are needed
for development. Material companies need industry brands to partner with them in developing and
improving the aesthetics and performance of next-gen materials to match and eventually to surpass their
animal-based counterparts.
With better expectation management, industry brands can work with material companies to overcome
the inevitable challenges. In this section, we consider solutions from the perspective of designer,
manufacturing partner, and industry brand.

A Designer’s Perspective IN
There is definitely a wow factor when you can tell your customers that “Designers are looking for beautiful
your bag is made from pineapple, mango, cactus, corn, or apple. materials that perform - don’t crock or
crack, can withstand daily abrasions
And Jessica Kruger, founder of London-based luxurious vegan accessories
and the occasional spill - and are
brand LUXTRA, has worked with many of these next-gen materials. available for sampling with production
quantities ready to ship within the
usual fashion production lead times.
We also like to customize products to

differentiate from other brands. That
might include ‘stamping’ a logo or
printing a pattern onto the material.
These are services that most brands
are accustomed to receiving when
working with a supplier.
Brands will not want to pay more

than they do for the animal-derived
LUXTRA bag made with Piñatex® material. Every brand has material
budgets. But I would say it’s important
There are many less-fun moments, however. These might occur when testing for brands to make a commitment
to material innovators. One of the
a material, only to find that it cracks and disintegrates when out in the real
things that fashion should do better
world. Or perhaps a promising material is only available in three colors. Or (and there are many!) is to do more
maybe it’s when the trusted manufacturing partner that has decades of partnering with material makers.
Erratic orders from brands make
working with real leather has no idea how to work with the new material
it difficult for material companies
and the prototypes look terrible. These are just a few examples of Jessica’s to employ people consistently and
struggles with innovative materials. safely. At this moment when we have
so many innovators on the cusp of
changing the material world, they
Jessica’s wish list for the perfect material:
could really use this commitment
from brands.”
1. The perfect material is circular. Brands and designers endure the initial
pain of working with an unfamiliar material to create more sustainable and
environmentally friendlier products. If this box cannot be checked and if
sustainability claims are limited (e.g. because the backing of a material is
primarily plastic), there is much less incentive to work with the material.
2. The perfect material has high marks in performance. This includes good
scores from the Martindale abrasion test, for example. The material can’t crack
or disintegrate with use, and the surface should be smooth and appealing: no
chunks that make the material surface uneven. Durability is also key.
-T
homasine Dolan, Fashion
Design Specialist of MII
3. The perfect material is beautiful. Aesthetics matter to designers. But for a
material to really start to compete with the mainstream options, brands will
want to see choice. A range of colours, finishes (glossy, matte), textures (smooth,
pebbled) and emboss-ability (i.e. to ensure stamped logos will not rub off or
flatten out with time).
Other practical concerns include lead time, location of the material (to minimise
the carbon footprint), and price.

A Manufacturer’s Perspective
Most industry brands have manufacturing partners, including mills and factories,
that they rely on to execute a design. Significant initial investment of time
and resources is required to test and tweak new materials to make them work
with existing machinery, with the skills and experience of workers, and with
sourcing procedures.
Veshin Factory. Xiao Wei, Executive Director (left) and Hongliang Yu, Co-owner (right).
This can be a bottleneck to transitioning into next-gen materials. Joey Pringle, co-
founder of Veshin Factory, is on a journey to turn a decade-old factory specialising in
manufacturing premium leather goods for luxury brands into a vegan factory.
After a year of testing and working with many next-gen materials, including cactus
leather, and turning them into end products for 6 brand clients, Joey knows that
collaboration is key. It is important to have a manufacturing partner who is willing to
sit down with the material innovators and the brands to consider the best ways to
work with innovative materials.

Traditionally, the industry operates in two-way
relationships. Brands order directly from material
suppliers and send directly to the manufacturer.
However, with novel materials this often creates
friction. Joey is trying to make this a three-way
relationship by bringing brands, material innovators,
and manufacturers together.
In order to help next-gen materials scale quickly, Joey

is taking the initiative to support his clients (brands)
by doing the groundwork for them. From the very
beginning, Joey invests time and resources to test
and experiment with a next-gen material. Using his
in-depth knowledge and experience with product
specifications required by the brands, Joey can provide
feedback and work on re-iterations with material
innovators early in development. Many pain points and
risks associated with using a new material, both from
the brand and the material supplier perspectives, can
be mitigated by a manufacturer with expertise with
that material in the relationship. With today’s push for
a more ethical and transparent supply chain, having
a trustworthy three-way relationship also enables
brands to confidently educate their consumers about
the materials they use and the manufacturing process
that has gone into making its products.
A Sourcing Perspective
“Fashion brands recognize the trend toward more sustainable and animal-free materials.
We have met with forty fashion, automotive, and home goods brands, and all but two are
actively searching for next-gen materials to integrate into their supply chains.
The current materials industry does not yet produce sustainable options at scale that
meet brands’ performance, aesthetics, and price requirements. When we help brands
source these next-gen materials, we encounter very few existing options that meet a
brand’s specifications and hit their sustainability goals. We continue to reiterate that
perfection cannot be the enemy of good. In other words, although we are not quite there
on 100 percent cradle-to-cradle sustainability, moving to next-gen raw materials will have
significant positive environmental impacts.
- Jacqueline Kravette,
Additionally, although brands are excited to be pioneers and leaders in utilizing these
Chief Brand Officer of MII
materials, they are learning that it requires time, effort, and collaboration with innovators to
form a true partnership. Other options are brands that are conducting their Research and
Development in-house. However, as most are discovering, the time, people, and expense
needed for that option are better found out of house with innovators in all stages
of development.”

PART C:
OTHER DRIVING
FORCES

7. ADVANCEMENTS IN SCIENCE
AND TECHNOLOGY
Innovation in the next-gen materials industry is T

issue engineering and bioprinting.
fueled by recent advancements in science and Further along the development pipeline,
technology. Deep tech innovation, aimed to we see cell-based technology take shape in
replicate the intricate structure and composition the form of lab-grown tissues. Similar to precision
of animal-derived materials, is poised to come fermentation, tissue engineering first took hold
to market shortly. Many of these innovations are in the biomedical industry. The first tissue-
founded on platform technologies that rely on engineered product for skin burn treatment
versatile approaches to material development, was commercially available in 1998.17 Since then,
and will have broader reach than the design of a lab-grown meat has entered the marketplace,
one-time material composition. Key innovators are where the muscle that comprises beef, chicken,
building intellectual property portfolios in these or seafood can be grown in cell culture medium
technology spaces that will be essential to their in a laboratory. Lab-grown leather applies this
long-term success. Below are a few examples of same technology to materials. (See Figure 7.1)
recent advances in science and technology that are Bioprinting, or the use of 3D printing to create
paving the way for next-gen innovation. living tissue structures, may soon find commercial
relevance in replacing animal materials. Over
10,000 scientific publications and 9000 patents in
the tissue engineering field have been published
BIOTECHNOLOGY:
in the last 20 years.18
Precision fermentation. Precision fermentation

M
ycelial growth. Unlike the yeast (a type of
uses microbial hosts as factories to produce
fungi) cells used in the aforementioned precision
target compounds. Fermentation has been
fermentation processes, multicellular fungi have
used since early humanity for brewing alcoholic
paved the way for a unique subset of materials
beverages or fermenting foods, but recent
derived from the root-like structure of mycelium.
advances in biotechnology have enabled this
This fast-growing, fibrous structure first found
process to apply to a wide range of industries.
applications as an alternative to styrofoam
Recombinant DNA technology, or the use
packaging material,19 and is now taking hold as
of genetic engineering to produce foreign
a replacement for meat or leather. With at least
molecules in microbes, was first applied to high
seven innovators employing this technology,
value, low volume biomedical products such as
a diverse intellectual property landscape is
insulin in the 1980s.16 However, recent advances in
emerging surrounding mycelium.20
genome sequencing and editing, alongside cell
culture process optimization, have led precision
fermentation to be used to produce lower value,
high volume products such as alternative food
protein. Now, a biotech revolution in materials is
setting the stage for commercial production of
proteins, biopolymers, and chemical precursors
for next-gen material formulations.

Figure 7.1 Lab-grown Leather Process
Source: Material District, “Help the Planet with lab grown leather? 2,” materialdistrict.com, Mar
31 2015. https://materialdistrict.com/article/help-the-planet-with-lab-grown-leather/help-the-
planet-with-lab-grown-leather-2/#moved
BIOBASED CHEMISTRIES:
Novel composites technology. Outside B

ioplastics. Although petroleum-derived plastics
of the biotech boom, there have still been have created a host of environmental problems,
advancements in more traditional aspects the versatility and range of properties offered
of materials science such as composites by synthetic polymers such as polyester and
manufacturing. Natural Fiber Welding combines polyurethane are unrivaled in the materials
novel bio-based resin chemistries to weld natural industry. Innovation in bio-derived plastics and/
fibers, producing composite structures that can or plastics that are biodegradable has enabled
be tuned for specific performance requirements. next-gen materials to reduce their reliance on
Based on patented technology licensed through fossil fuels and to prevent the accumulation of
the US Air Force, this military-grade tech will plastic waste in the environment. For example,
soon be consumer-facing in the form of Dupont’s Sorona, a biobased polyester, is used in
next-gen leather. 21
the formulation of next-gen fur, and bio-based
polyurethane is used as a coating or binder
in several next-gen leather compositions. The
bioplastics market is expected to grow to $26B by
2027, with textiles occupying the second-largest
market share aside from packaging.22

8. CONSUMER PREFERENCE
Although consumers appreciate the quality of MII’s exploratory study examined U.S. consumer
animal-based materials, their impact on the purchasing preferences for leather and leather
environment and on animal welfare continue to alternatives. We collected survey responses
give rise to the desire for high quality alternatives from a sample of 519 individuals across the U.S.
more in line with consumers’ values. This through Amazon Mechanical Turk. We segmented
expectation of values orientation in fashion consumers by whether they preferred animal
choices is especially prominent among younger leather or leather alternatives. 45% of respondents
generations.23 preferred animal leather while 55% of respondents
preferred alternative leather. (Figure 8.1)
As the bulk of innovation in next-gen materials
is in leather alternatives, the Material Innovation Those who preferred animal leather (45%)
Initiative undertook a study of U.S. consumers to appreciate the high quality, durability, and
obtain preliminary data on consumer interest in authenticity of animal leather and enjoyed the soft
and reasons for purchasing leather alternatives, feel, smell, and breathability. Those who preferred
as well as consumer perceptions of product leather alternatives (55%) appreciate the altruistic
attributes, openness to different production benefit for animals and the environment and
technologies, pricing, and preferences for message enjoyed the affordability and low maintenance
framing.24 Currently, little data exists regarding aspects of alternative leathers. Being animal-free
consumer acceptance of any next-gen materials. and affordable were the top attributes of leather
Our exploratory study begins a research agenda alternatives for both consumer segments.
to better understand consumer attitudes and
behavior towards new materials that are high Even among U.S. consumers who prefer animal
performance, more sustainable, and animal-free. leather, at least 45% consider alternative leather
more fashionable and better for the environment.
As expected, consumers who prefer alternative
Figure 8.1 Material preference between
leather had higher overall rates of agreement in all
animal leather and alternative leather
categories: over 75% consider alternative leather
Animal good for the environment and fashionable, 87%
Leather see it as affordable, and 92% as good for animals.
45%
(Figure 8.2)
Alternative
Leather
55%

Figure 8.2 Percentage of Participants who agreed with each attribute statement about alternative leather
Note: The percentage includes both participants who ‘agreed’ or ‘strongly agreed’ with each statement.
92% Those who prefer alternative leather

Good for Animals
69% Those who prefer animal leather
Affordable 87%
67%
Appealing 86%
39%
Fashionable 76%
45%
75%
Good for the Environment
47%
72%
Durable and Long-lasting
34%
68%
High Quality
31%
56%
Good for Workers
37%
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%
We then examined how open each group was Among those who prefer alternative leather:
to purchasing materials made using different 96% were open to purchasing
technologies and ingredients. We tested consumer 67% were enthusiastic about purchasing
preferences for (1) acrylic or polyester materials; (2)
plant-based fibers; and (3) materials grown from
REAL LEATHER GROWN FROM
animal cells in a factory.
ANIMAL CELLS IN A FACTORY
LEATHER MADE OUT OF ACRYLIC Among those who prefer animal leather:
OR POLYESTER MATERIALS 80% were open to purchasing
37% were enthusiastic about purchasing
Among those who prefer animal leather:
7
1% were open to purchasing Among those who prefer alternative leather:
1 7% were enthusiastic about purchasing 73% were open to purchasing
34% were enthusiastic about purchasing
Among those who prefer alternative leather:
9
2% were open to purchasing This research indicates a strong market for next-
5
0% were enthusiastic about purchasing gen leathers even among those who prefer animal
leather. Both consumer segments preferred leather
made from plant-based fibers and leather grown
LEATHER MADE OUT OF PLANT FIBERS from animal cells over polyester and acrylic-based
leather. One of the main reasons for preferring
Among those who prefer animal leather: animal leather over alternative leather was a
8
0% were open to purchasing concern about quality. As alternative leathers
2
5% were enthusiastic about purchasing continue to improve in performance, it is likely that
the market will continue to grow.

As the expected price for next-gen leathers is
higher than animal-based leathers, we also asked
consumers how much more, if anything, they
would be willing to pay for alternative leathers that
are animal-free and more sustainable. Among
those who prefer animal leather, 56% would not pay
more, 25% would pay 10% more, 9% would pay 25%
more, 9% would pay 50% more, 2% would pay 100%
more. Among those who prefer leather alternatives,
31% would not pay more, 39% would pay 10% more,
22% would pay 25% more, 6% would pay 50% more,
and 2% would pay 100% more.
Among those who prefer animal leather:

O
verall, 44% would pay more
2
0% would pay at least 25% more
Among those who prefer alternative leather: Jo-Anne Vernay made with Piñatex® by Ananas Anam
6
9% would pay more
3
0% would pay at least 25% more These results provide a first look at U.S. consumers’
preferences for alternative leathers and show a
This survey suggests that consumers are willing to clear preference for next-gen leather over animal-
pay more for products that align with their values based leather. As consumers who preferred
but still meet their aesthetic and performance animal-based leathers did so because they were
needs. Surprisingly, 44% of consumers who prefer perceived to have higher quality and performance
animal leather are willing to pay more for next-gen attributes, we expect these consumers will be open
leather products and 20% of them are willing to pay to switching to next-gen leathers when they are at
at least 25% more than they are currently paying. price, quality, and performance parity.
IN
Our study showed that consumers who prefer

animal-based leathers do so because animal leathers
are seen as having higher quality and performance
attributes. These consumers will be open to switching
to next-gen leathers when they are at price, quality,
and performance parity. Most consumers will even be
willing to pay more for products made from next-gen
materials that align with their values.

9. REGULATORY CHALLENGES
AND OPPORTUNITIES
INCREASED CONCERNS are increasingly requiring those companies in
ABOUT SUSTAINABILITY their portfolios to pass sustainability thresholds.27

COVID-19 has also pushed governments to do more
More and more people are concerned about about sustainability, with many European regional
sustainability in their fashion purchases. and national authorities tying post-COVID recovery
Consumers, especially Millennials and Gen Z, are efforts to sustainability objectives.28
expressing desires to purchase more sustainable

products. In a McKinsey & Company consumer
research study of U.K. and German consumers INCREASED FOCUS ON ANIMAL
conducted in April 2020, 67% of those surveyed WELFARE INCLUDING BANS ON
consider the use of sustainable materials an ANIMAL-BASED MATERIALS
important purchasing factor, and 63% consider a
brand’s promotion of sustainability in the same In the past two decades, concern for animal welfare
way.25 Similarly, Lenzing Group, a global leader has brought about an increase in the number of
in sustainably produced wood-based specialty animal welfare certifications, as well as bans on
fibers, conducted a consumer perception study certain husbandry practices and on the production
in early 2020 of 9,000 respondents across nine or use of certain animal-based materials. We
countries aged between 18 and 64 on “Sustainable see this concern for animal welfare continuing
Raw Materials in Fashion and Home Textiles.” The especially as the market offers consumers more
majority of respondents, 86%, said that purchasing choices that meet their aesthetic and performance
clothes made from sustainable raw materials is needs and are cruelty-free and more sustainable.
a key component of living a more sustainable
lifestyle. 80% of respondents said they frequently Industry trade associations and independent
purchase products from brands committed nonprofits continue to implement animal-welfare
to using sustainable raw materials. 40% of standards to comply with increased consumer
respondents said they are willing to pay an average concerns over the treatment of animals. Examples
of 40% more for clothing or home textile products include the International Wool Textile Organisation
with descriptions that reflect sustainability. (IWTO) Guidelines for Wool Sheep Welfare;29 Textile
About 50% of fashion executives in a recent opinion Exchange’s Responsible Leather, Wool, Down,
poll indicated that sustainability has become more Mohair, and Alpaca Standards;30 and Kering’s
important during the COVID-19 pandemic.26 We are Animal Welfare Standards.31
seeing this trend in our work with brands. “Out of
40 brands we have met with, 38 are actively looking Brands are Increasingly banning the use of certain
for more sustainable materials. The brands we materials. Burberry, Gucci, and Prada banned the
have spoken to recognize that consumers want to use of fur. Chanel, Diane von Furstenberg, and
purchase more ethical products, especially younger Mulberry banned many exotic skins, and PVH,
generations, and the brands want to get ahead of which owns Calvin Klein and Tommy Hilfiger,
the trend.” Jacqueline Kravette, Chief Brand Officer, banned angora, fur, and exotic skins.32 Some
Material Innovation Initiative. In addition, investors luxury brands such as LVMH33 and Hermès34

have expressed their concern for animal welfare the end products, rather than the process by which
by building new production facilities and bringing they were produced.38 It is worth noting that GM
the production of exotic skins under their control. cotton has been widely approved for decades and
Hermès is also betting on next-gen mycelium currently comprises 90% of U.S. production39 and
leather through a partnership with MycoWorks. 35
has been the most widely sown GM crop in Mexico
for 20 years.40
Fashion shows all over the world are joining brands
in banning certain animal materials from the
runway. Stockholm’s Fashion Week banned fur LABELLING RESTRICTIONS
and exotic skins in fall 2020, London Fashion Week
banned fur in 2018, and the Melbourne and Helsinki We expect that producers of animal-based
fashion weeks banned exotic skins in 2018.36 materials will challenge the use of tems like
“leather” and “fur” for next-gen materials, just as
In addition, many countries are implementing animal-based meat and dairy producers challenge
more stringent animal-welfare regulations or the use of “burger” and “milk” when applied to
outright banning the production or sale of some plant-based foods.41 The International Council
animal-based materials. For example, over the past of Tanners has already begun to track labelling
two decades, twenty countries have voted to ban restrictions on these terms, stating that “the correct
fur production, to prohibit the farming of particular labelling and description of leather and leather
species, or to implement stricter regulations.37 products is very important in order to protect
both the leather market and consumers against
misdescriptions.”42 In May 2020, Italy banned the
LOW REGULATORY BURDEN use of the terms pelle/cuoio (leather) to identify
TO MARKET ENTRY materials that do not have an animal origin.43 The
UNIC, the Italian Tanneries Association, specifically
The main regulatory burdens to market entry for praised the law for the “express prohibition of the
next-gen materials are the standard burdens placed use of the words skin and leather, also as prefixes
on other materials used in similar applications. The or suffixes, to identify materials not derived from
main regulations include restrictions on hazardous the remains of animals, such as today it occurs with
chemicals and compliance with flammability the unorthodox terms eco-leather, vegan leather
standards. In the United States, these regulations and the like used for synthetic materials.”44 Because
include California Proposition 65, Federal Hazardous restrictions on the use of “leather” follow the same
Substances Act, the Consumer Product Safety reasoning as proposed restrictions for “milk” and
Improvement Act, and the Flammable Fabrics Act. “burger,” we anticipate that such labelling laws will
The hazardous chemicals restricted by California ultimately not survive legal challenges.
Proposition 65 and Federal Hazardous Substances
Act are not typically used in the production of next-
gen materials.
Although some next-gen materials may include Belts made with Viridis®
genetically modified materials, the restrictions

on non-food GM products are much lower than
regulations governing GM ingredients for human
and animal food. Producers should review
the regulations in the country of production
and countries of sale of their materials as GM
regulations can vary significantly between
countries. The United States has one of the more
liberal approaches, which focuses on the nature of

10. CONCLUSION
This report represents the first time the emerging Of the total 74 companies innovating in next-gen
industry of next-gen materials—high performance materials, 42 were established since 2014. Thirty
and more sustainable alternatives to animal- of these 42 new companies focus on leather
derived materials—is analysed and presented in a biomimicry.
way that aims to inspire different stakeholders to
take action. Investment in next-gen material innovation
reached new heights in 2020. The investment
Conventional livestock-derived materials such amount in 2020 alone is nearly the same as in
as leather, fur, silk, wool, down, and exotic skins, the previous 4 years combined. Even amid the
are widely used in the fashion, home goods, and Covid-19 pandemic, this trend continued. By mid-
automobile industries. 2020 highlighted that raising May 2021, 4 of the top 10 funded companies have
animals for their skin, fur, or feathers can be a risky successfully raised new rounds. Investment is
business with low margins and high variability. expected to further increase as companies mature,
Going forward, the greatest opportunities lie demonstrate proof of concept, and scale.
in developing technology and materials that
inherently meet market demand for sustainability, Industry brands have taken actions with respect
style, and performance. to material innovation through internal R&D,

investments, and partnerships. Many brands also
have sustainability commitments to completely
switch to, or significantly increase the use of,
more sustainable materials by a certain year.
Such commitments present more opportunities
for material innovators and suppliers.
Acceleration of the next-gen materials industry

is fueled by recent advancements in science and
technology, by regulatory trends, and by consumer
preferences. Deep tech innovation, aimed to
replicate the intricate structure and composition
of animal-derived materials, is poised to come to
market soon. Technologies have the potential to
significantly transform the industry by creating
materials that meet brands; and consumers’
aesthetic, performance, and price needs and
that are also more sustainable and animal-free.
Technology is already disrupting the materials
market and will continue to do so. Those who
are quick to adapt have the opportunity to reap
massive financial benefits by staking their claim on
the materials industry of the future.
As we face potentially dire climate change, this is

not the time to take it slow. We need significant
investments, partnerships, and more material
companies and scientists tackling the issues
facing the industry. Collaboration is the path
forward. Now is the time to embrace sustainable
innovation, both to create a liveable future on
Earth and to create a prosperous future for the
materials industry.
Let’s make the sustainable option the

default option. KD New York Vegetable Cashmere™ sweaters

BONUS SECTION
BONUS: PROJECTION OF GROWTH OF THE NEXT-GEN MATERIALS MARKET
We estimate that the global wholesale market size enthusiasm for sustainable alternatives to
for next-gen materials will be approximately $2.2 transport.45 While we don’t anticipate next-gen
billion (USD) in 2026, representing a 3% share of an materials will grow as quickly, our research
addressable market of over $70 billion. suggests that the industry will grow at 80%
annually over the next 5 years as new materials
In forecasting growth for the next-gen industry begin to enter the market.
over the next 5 years, we look towards the success
of other industries such as electric cars, alternative We see the next-gen materials industry as
proteins, as well as plastic alternatives to derive a 5-10 years behind where the alternative protein
plausible growth rate as new innovative companies industry is currently. In 2019, McKinsey & Co.
begin to come to market. For example, data from estimated the market base for alternative protein
International Energy Agency (IEA) suggests that the at approximately $2.2 billion compared with
electric car industry experienced a CAGR of 125% a global meat market of approximately
between 2010 to 2015 as consumers demonstrated $1.7 trillion.46
Figure 11.1 Projection of growth of the next-gen materials global wholesale market (2021-2026)
2,500
2,000 2,205
Market size (USD million)
1,500
1,000 1,225
R 80%
CAG
500
680
378
0
210
65 117
2020 2021 2022 2023 2024 2025 2026
Sources: MII / SPEEDA Edge analysis.

Figure 11.2 Next-gen material global wholesale market (billions in USD and market share in %)
CAGR (2020-2026)
Next-gen 2.2B (3.0%) +80.0%

Next-gen Current-gen 20.2B (27.4%) +8.1%
65M
(3.0%)
Animal-derived 51.2B (69.2%) +2.0%
2020 2021 2022 2023 2024 2025 2026
Sources: MII / SPEEDA Edge analysis.
IN
WHY IS OUR PROJECTION SO “SMALL”?
Much larger market projections have been made, including this one: The synthetic leather market
size is estimated to be USD 63.3 billion in 2020 and is projected to reach USD 78.5 billion by 2025, at
a CAGR of 4.4% between 2020 and 2025.47
But do these projections compare apples to apples? We use wholesale prices in coming up with
our market size projection. The market size for end products (e.g., garments in fashion, bedding
in home goods, seats in automobiles) is likely at least several times larger. We chose wholesale
instead of retail prices, because this analysis is primarily for companies in material innovation and
for investors looking to invest in these companies. For example, for the leather sub-category, we
analysed the leather material market, not the leather goods market.
“Current-gen” replacements of animal-based materials that hold a significant share (just over 20%
as of 2020) of the addressable market are also not included.
It is worth noting that the total addressable market is a sizable $70 billion. The next-gen material
industry is nascent now, but we project it will grow quickly. We applied a compound annual growth
rate (CAGR) of 80% between 2020 and 2026.

Forces accelerating the next-gen materials Spiber is just one example of a company that has
industry include: expanded its reach.
Although Spiber’s initial focus was creating silk and

A DISRUPTED ANIMAL cashmere-like materials, their Brewed Protein can
AGRICULTURE INDUSTRY also be woven or knitted into fabric, or processed
into non-woven, fur-like or hair-like materials. The
The livestock industry has developed revenue raw protein polymer can be dissolved in solvents
streams for every part of an animal (hides, bones, to make a film or combined with other materials
connective tissue, etc.). The hide, for example, is the like carbon fiber to make composites. The flexibility
second most profitable product of the cow.48 This of many next-gen material companies to expand
cost structure creates vulnerabilities, however. 49
across verticals means they are likely to venture
When alternatives for one stream of animal product beyond the addressable market we estimate here.
achieve parity in price and quality, the price of
other conventional streams will be driven upwards Our projection of how fast the next-gen materials
to compensate for the diminishing stream. The industry will grow to replace animal-derived
alternative protein market—replacement of animal materials (77.4% of the 2020 market), is based
meat, eggs, and milk—is on track to garner as primarily on the economics of the animal
much as 22% of the global protein market by 2035. 50
agriculture industry. The tipping point for a
The cost of these alternative proteins will eventually transition toward non-animal-derived foods,
be 50-80% lower.51 As more consumers make the ingredients, and materials will occur sooner than
switch to alternative proteins, prices of animal- generally expected because the current economics
derived materials will rise. of the conventional animal products industry
necessitate value-creation from every part of the
The animal agriculture industry is a break-down or animal.53
extraction model, whereby a whole animal is grown
to be broken down into simpler products that are
then sold into different industries and markets. THE TURN AGAINST PLASTIC
The replacements, whether alternative proteins or
next-gen materials, operate by a build-up and build- Consumers are increasingly demanding more
on-demand model. This opposite approach means sustainable and cruelty free products. The
at least two things for industries seeking to replace relationship between meat consumption and
animal-based, break-down models with alternative, climate change has increased significantly over the
build-up models: (1) more efficient feedstock past few years, but fewer consumers have made
conversion (e.g. 4-11% in the case of animals versus the logical connection and link animal-derived
40-80% in the case of precision fermentation); and
52
materials with climate change at this point.
(2) a production cycle measured in days, not months
or years taken to grow and process animal products. They are currently a lot angrier, and driven to take
action, by something else.
Moreover, because some companies are creating
building blocks, not finished materials, a much wider The public turn against plastic was not foreseen
variety of potential products is possible. A number of by scientists or environmental activists. “I scratch
companies have expanded from alternative proteins my head about it every day,” says the Imperial
into next-gen materials and vice versa. Others have College oceanographer Erik van Sebille. “How is
created building blocks for applications in skincare plastic public enemy No 1? That should be climate
or medicine. change.”54

Regardless, brands are increasingly taking note As discussed in section 6, fashion and automotive
of this demand from customers. As we have seen brands are willing to switch to next-gen materials
in section 6 (in particular table 6.2 Sustainability once they meet the necessary sensory, tactile,
Commitments of Industry Brands), many brands and sourcing specifications for their products.
have made specific commitments to replace, MII has met with 40 major international
decrease the use of, and/or recycle polyester and fashion brands, all but two are actively looking
other petroleum-based plastics. for sustainable and animal-free materials
because of customer demand. We are assisting
Plastic is everywhere. Today’s cars are about 50% them in sourcing next-gen materials. These
plastic by volume. More clothing is made from brands will likely set the trend for the rest of
polyester and nylon, both plastics, than from cotton. the industry.
Plastics also made their way into substituting for
animal-derived materials by winning on price— As discussed in section 8, consumers are willing
synthesized leather made from petrochemicals to shift away from animal-derived materials.
sells at wholesale at one-third the price of their We anticipate that they will move away from
animal leather equivalent. In our projection, we call materials made from animals more quickly than
these petroleum-based alternatives (e.g., PU/PVC, from foods made from animals. People don’t
acrylic fiber) “current-gen.” generally have the same emotional or cultural
attachment to materials as they do to food.
Given the consumer turn against plastic, the People don’t say: “I just can’t give up leather” like
growth of next-gen materials will be driven they say: “I just can’t give up cheese.” Consumers
partly (or even significantly, in the beginning) by don’t generally mind technology in their clothes,
the demand to replace current-gen alternative homes, and cars, and sometimes technology makes
materials. Because plastic and petroleum- those items even more desirable. But consumers
derived materials are much more than cheaper are sometimes reluctant to accept novel foods.
replacements for animal-derived materials, next- Consumers also use and purchase animal-free
gen material companies that develop alternatives materials already, and in many cases, they are not
to current-gen materials may be looking at a much even aware of the difference. Consumer research
bigger addressable market than covered here. data confirms willingness to switch: 55% of
American consumers would prefer purchasing a
leather alternative and 76% of American consumers
THE RELATIVE LACK are likely to purchase leather grown directly from
OF BARRIERS animal cells without the need to raise and kill
an animal.
We are optimistic of a fast and vast shift from
animal-derived materials and current-gen Perhaps more importantly, as discussed in section
alternatives to next-gen materials because of 9, the regulatory hurdles are significantly less for
the relative lack of barriers in terms of consumer introducing a new material to market than for
acceptance and regulatory hurdles. a novel food.
A special note on silk alternatives

Although our analysis assumes a modest 3% future market share for next-gen materials
overall, we anticipate that silk alternatives will greatly impact other markets. Microbe-
derived spider silk protein, for example, could solve pain points across a variety of industries
that cannot currently be addressed by legacy silk.

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ACKNOWLEDGEMENTS
Principal Author
Elaine Siu
MII Chief Innovation Officer
Editor
Anne Green
MII Project Manager
Contributors
Sydney Gladman, Ph.D, MII Chief Scientific Officer
Fernanda Mota Onça, MII Innovation Assistant
Abhirath Kumar, Ahimsa VC
Nicole Rawling, MII Chief Executive Officer
Research Partner
Layout Designer
Adam Cohen
We’d also like to thank the leading next-gen material companies, industry stakeholders,
and investors for their generous input and support.
ABOUT MII
The Material Innovation Initiative is a nonprofit that accelerates the development of “next-gen” (high
performance, animal-free, and more sustainable) materials for the fashion, automotive, and home
goods industries. Technological innovation and untapped natural materials have the potential to
transform the materials industry and solve the enormous environmental challenges it faces.
We work for materials that can do more, while requiring less of the planet, animals, and people involved
at every stage. We imagine a circular future where the default choice for your sweater, sneaker, or seat is
humane and sustainable; a future where animals are allowed to live free and thrive, where the planet is
saved from pollution and degradation, and where workers are treated fairly and with respect.
MII’s team of experts advance innovation in three main ways:
1. identifying and assessing innovative materials and technologies;

2. spurring investments, research, and development to scale innovations; and
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State of The Industry Report Next-Gen MAterials

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STATE OF THE

2 © 2021 Material Innovation Initiative

3 © 2021 Material Innovation Initiative

$504 $599 MATERIAL

Source: Material Innovation Initiative

Look for the IN logo throughout this report

4 © 2021 Material Innovation Initiative

PART A: A NEW INDUSTRY IS BORN 6 PART C: OTHER DRIVING FORCES 47

1. Introduction 7 7. Advancements in Science and Technology 53

PART B: KEY STAKEHOLDERS 18 10. Conclusion 55

4. Innovators 19 BONUS: MARKET SIZE AND 57

5. Investors 28 The Turn Against Plastic 59

5 © 2021 Material Innovation Initiative

6 © 2021 Material Innovation Initiative

Conventional livestock-derived materials such as

“The term next-gen cues innovation, and may

7 © 2021 Material Innovation Initiative

FOUNDERS’ STORY (AND WHY WE CAN PREDICT THE FUTURE)

8 © 2021 Material Innovation Initiative

“The most significant quantum leap advancements

9 © 2021 Material Innovation Initiative

With clear interest from consumers and brands,

There is significant demand for next-gen materials,

“If there’s anything I’ve learned from my time

Natural Fiber Welding Production

11 © 2021 Material Innovation Initiative

MARCH 2021 MARCH 2021

12 © 2021 Material Innovation Initiative

WHAT ARE “NEXT-GEN MATERIALS”?

Leather Silk Fur Down Wool Exotic skins

DISRUPTIVE TEXTILE players and technologies may become promising

13 © 2021 Material Innovation Initiative

LUXTRA clutch purse made with

14 © 2021 Material Innovation Initiative

Source: Material Innovation Initiative

“The transformation of orange peel and algae into fabric

15 © 2021 Material Innovation Initiative

The most popular approach involves the use of

Due to the unique nature of the branched, fibrous

16 © 2021 Material Innovation Initiative

Hugo Boss shoes made with Piñatex® by Ananas Anam

17 © 2021 Material Innovation Initiative

18 © 2021 Material Innovation Initiative

Table 4.1 Next-gen material companies (in alphabetical order)

Company name Material name HQ Founders Year Biomimicry Main Input

Amadou Leather - GBR Irene Marie Seelig 2016 Leather Plant-derived

Articor Cork - ESP Unavailable 1986 Leather Plant-derived

Barktex - DEU Mary Barongo, Oliver 1999 Leather Plant-derived

Beyond Leather Leap™ DNK Hannah Michaud, 2016 Leather Plant-derived

19 © 2021 Material Innovation Initiative

Bio2Materials - POL Katarzyna 2018 Leather Plant-derived

Biophilica Treekind™ GBR Mira Nameth 2019 Leather Plant-derived

Biotecam Texticel BRA Ricardo Remer, Wim 2012 Leather Microbe-derived

C-Combinator - PRI Geoff Chapin 2020 Leather Plant-derived

Coronet Spa Coronet BioVeg, Enrico De Marco 1966 Leather Blend

Culthread - Rina Einy 2018 Fur Recycled

Desserto - MEX Adrián López Velarde, 2019 Leather Plant-derived

Devo Home - UKR Oksana Devoe 2008 Fur Plant-derived

EcoSimple - BRA Cláudio Rocha, Marisa 2010 Wool Recycled

“The term next-gen cues innovation, and may

“The most significant quantum leap advancements

“The transformation of orange peel and algae into fabric

- Elaine Siu, Chief Innovation