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Toxicology Urinalysis: Figure 1-1

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CHAPTER 1 Laboratory Essentials

AdmiHospi tal
n istrator

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MediAdmicalsRecords
sions ClRadi
i n icoalloLab
gy Respi ratory
Pharmacy AdmiFaci
n i s ies ve Bil ing CodiAccounti
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ng ng
I maging Rehabil itation Support Human Resources
• Figure 1-1 Hospital organ izational chart.

Hematology Immunol
Serologyogy/ Microbiology Toxicology II Uri nalysis
• Figure 1-2 Clinical laboratory organizational chart .

immunology and serology, urinalysis, specimen collection, Hematology


and customer service. The individual laboratory sections are Hematology is the study of blood cells. Blood cells include
described later (Fig. 1 -2) . erythrocytes (i.e., red blood cells) , leukocytes (i.e., white
blood cells) , and thrombocytes (i.e., platelets) . The most
Departments and Their Functions common test performed in this department is the com­
Clinical Chemistry plete blood count (CBC) , which is a summary of cell
Clinical chemistry is the medical discipline that uses various counts (i.e., red, white, and platelet) , total hemoglobin
methods of analysis and instrumentation to determine val­ level, red blood cell size, and hematocrit. A CBC usually
ues for chemical components in normal and diseased states, includes a differential count, which reports the percentage
types and concentrations of blood toxins, and therapeutic of each type of white blood cell in the blood sample. Cell
drug levels. Routine tests run by the clinical chemistry section counts for body fluids are also performed in this depart­
analyze levels of glucose, blood urea nitrogen (BUN), electro­ ment. Other tests include reticulocyte counts and erythro­
lytes, calcium, phosphorus, magnesium, lipids, liver function cyte sedimentation rates.
values, alkaline phosphatase, creatinine kinase, creatinine, In many laboratories, coagulation testing is performed
protein, albumin, and hemoglobin A1c. The clinical chem­ in the hematology department. Routine coagulation tests
istry department also runs hepatitis panels, tests for rubella include the prothrombin time (PT) and the activated par­
and human immunodeficiency virus (HIV) , and determines tial thromboplastin time (aPTT) . These tests assess the two
levels of antibodies in the blood. Hormone levels (e.g., thy­ major clotting pathways in the body.
roid-stimulating hormone, prolactin, follicle-stimulating
hormone) are tested in another section of this laboratory. Microbiology
The routine tests are usually run in the main clinical The microbiology department identifies microorgan­
chemistry department. The antibody and hormone levels isms that cause disease and determine the most effective
are usually considered subspecialties. Other subspecialty antibiotic to destroy bacterial pathogens. This department
departments include the toxicology, therapeutic drug mon­ grows cultures from major body systems such as the throat,
itoring, molecular diagnostics, and fecal analysis. Some urine, stool, wound, blood, eyes, ears, body fluids, nasal,
clinical chemistry laboratories have a section that analyzes abscesses, vagina, urethra, and tissues. Surgeons often per­
blood gases. form a culture after they drain or debride an infected area.

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