Week 2 Notes and Task
Week 2 Notes and Task
Week 2 Notes and Task
4. ____________________ 5. 6. ____________________
YOU JUST ME _______________________ XQQQQME
DEAL
What helped you answer these puzzles? __________________________________
Is it not because of the clues that the words themselves show? These puzzles intrinsically contain textual aids, which are the focus
of this module.
2 types
A. physical map - includes
labels for features such as
mountain ranges and
bodies of water
Live-attenuated vaccine
A live-attenuated vaccine uses a living but weakened version of the virus or one that’s very similar. The measles, mumps and
rubella (MMR) vaccine and the chickenpox and shingles vaccine are examples of this type of vaccine. This approach uses similar
technology to the inactivated vaccine and can be manufactured at scale. However, vaccines like this may not be suitable for people
with compromised immune systems.
Viral vector vaccine
This type of vaccine uses a safe virus to deliver specific sub-parts – called proteins – of the germ of interest so that it can trigger an
immune response without causing disease. To do this, the instructions for making particular parts of the pathogen of interest are
inserted into a safe virus. The safe virus then serves as a platform or vector to deliver the protein into the body. The protein triggers
the immune response. The Ebola vaccine is a viral vector vaccine and this type can be developed rapidly.
The subunit approach
A subunit vaccine is one that only uses the very specific parts (the subunits) of a virus or bacterium that the immune system needs
to recognize. It doesn't contain the whole microbe or use a safe virus as a vector. The subunits may be proteins or sugars. Most of
the vaccines on the childhood schedule are subunit vaccines, protecting people from diseases such as whooping cough, tetanus,
diphtheria and meningococcal meningitis.
The genetic approach (nucleic acid vaccine)
Unlike vaccine approaches that use either a weakened or dead whole microbe or parts of one, a nucleic acid vaccine just uses a
section of genetic material that provides the instructions for specific proteins, not the whole microbe. DNA and RNA are the
instructions our cells use to make proteins. In our cells, DNA is first turned into messenger RNA, which is then used as the
blueprint to make specific proteins. 18 CO_Q1_English10_ Module 2
A nucleic acid vaccine delivers a specific set of instructions to our cells, either as DNA or mRNA, for them to make the specific
protein that we want our immune system to recognize and respond to.
The nucleic acid approach is a new way of developing vaccines. Before the COVID-19 pandemic, none had yet been through the
full approvals process for use in humans, though some DNA vaccines, including for particular cancers, were undergoing human
trials. Because of the pandemic, research in this area has progressed very fast and some mRNA vaccines for COVID-19 are
getting emergency use authorization, which means they can now be given to people beyond using them only in clinical trials.
DIALOGUE TITLE:
Narration: