Gram Negative

Bacilli Respiratory
-

A.) i
 ✓
Bordetella Perfhsis Gram -

Bacilli

Highly Confessions , by respiratory doopkfs , goading foghe respiratory epithelium

using Pitti / Filamentous Hemm agglutinin ) → releases toxins Profess us foxing
→

ribosylation ldeaeoirqionloj
→ →

L Tracheal
Adenylate cyclase toxin ay like the Anthracis EF /Edema prefer) toxin
: →

Apoptocys Phagocytes Toxin Damage respiratory Epithelium Ñ¥¥%

→ 02 →

E Protein / inhibip CAMP) →

CAMP ↑ ↑
chemokines → gef speak blood stream 1-
ymphcypsis
Lymphocytes in
→ →

Symptoms
:
trooping cough / Paroxysms ) ! !! due to swollen Airways

macrolides
Treatments
:

Vaccines →
D T
aP
Diphpr
! ↓ A- cellular Pertussis Ag
Tegan as

catarrhal Phase tweets : in RT → Nasal

Congestion tough
, ,
tou grade fever

Paroxysmal Phase H -6 Weeks ) :

trooping cough →
Vommifing , collapsed lung Broken
,
ribs
,
facial Patechea

Phase 12-6 Weeks )

Convalescent :
symptoms slow down

-
PCR
 ✓ Haemophilus Influenzae Gram Negative Cocco Bacillus

•
Flora of fhl URT , Non-motile , facultative Anaerobic

Cafalase & oxidase Positive

•
Grown on chocolate Agar Nicotine Amide + Adenine Dinucleotide +
Hematin
will
create convex , smooth Gray / transparent
,
colonies

capsule have anti -

Phagocytic ability
•
Aerosol transmission
• Can cause :

Epigloffijs -

Inflamed Cherry Red

Epiglottis Respiratory spider drooling
, ,

Media
Ofip 's

Meningitis By capsulated B- sprain Increased risk

of infection in sickle cell or A
splenic Papienp
-

Cellulitis of fate , osteomyelitis septic arthritis ,

bragging )
Uncaps wlaped sprains IgA Propose opsonize s invading Baeiperia
• → →

[
[> Can change their Olisosaec on
their membrane / Phase variation )
can create Biofilm
Vaccine for type B
•

Treafmenf :

Given in
sprain which is Polysaccharide conjugated for Diphtheria toxoid
ages 2- 18
months

ceftriaxone is given for men

gijs / systemic disease

Rifampin prophylaxis in close conpaep

- Comma

3rd Sen

Azithromycin
-

ciprofloxacin
 ✓ Legionella Pneumophila Gram Negative Giver spinning

u
Oxidase .
Positive
•
Grown on chocolate yeast eiofraef -

requires presence of iron & cysteine

&
•

Pontiac fever -

self limited fever malaise

•

Legionnaires disease -

more common in smokers .

x-ray shows pafehyinjilpafe with
Headache, confusion
consolidation of A lobe .

May present Hyponatremia , ,

→

→
Pneumonia + Diarrhea , High fever Cnooc ≤ I

Testing
Blood
: Urine As fesf may be used for rapid diagnosis +
chest ✗ray Popchytilprafe
will lobe
analysis show Hyponatremia 1-
Leukocyposis Thrombocytopenia
+ 0h one

Treatment : Macrolides , fluoroquinolones

Azithromycin Levofloxacin

•
Aerobic

Facultative Intracellular
cafala.se Positive
•