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    Dilution Formula

    Uploaded by

    Fazilah Shahrom
    This document provides information on the reconstitution and stability of various drugs commonly used in the neonatal intensive care unit (NICU), including: - Reconstitution instructions and concentrations for antibiotics like amikacin, amphotericin B, azithromycin, bactrim, gentamicin, fluconazole, cefepime, ceftriaxone, cefotaxime, cefuroxime, ceftazidime, cefoperazone, metronidazole, meropenem, penicillin G, unasyn, sulperazone, tienam, tazocin, teicoplanin, vancomycin, linez

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    Dilution Formula

    Uploaded by

    Fazilah Shahrom
    86 views2 pages
    This document provides information on the reconstitution and stability of various drugs commonly used in the neonatal intensive care unit (NICU), including: - Reconstitution instructions and concentrations for antibiotics like amikacin, amphotericin B, azithromycin, bactrim, gentamicin, fluconazole, cefepime, ceftriaxone, cefotaxime, cefuroxime, ceftazidime, cefoperazone, metronidazole, meropenem, penicillin G, unasyn, sulperazone, tienam, tazocin, teicoplanin, vancomycin, linez

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    Dilution formula

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    This document provides information on the reconstitution and stability of various drugs commonly used in the neonatal intensive care unit (NICU), including: - Reconstitution instructions and concentrations for antibiotics like amikacin, amphotericin B, azithromycin, bactrim, gentamicin, fluconazole, cefepime, ceftriaxone, cefotaxime, cefuroxime, ceftazidime, cefoperazone, metronidazole, meropenem, penicillin G, unasyn, sulperazone, tienam, tazocin, teicoplanin, vancomycin, linez

    Copyright:

    © All Rights Reserved
    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
    86 views2 pages

    Dilution Formula

    Uploaded by

    Fazilah Shahrom
    This document provides information on the reconstitution and stability of various drugs commonly used in the neonatal intensive care unit (NICU), including: - Reconstitution instructions and concentrations for antibiotics like amikacin, amphotericin B, azithromycin, bactrim, gentamicin, fluconazole, cefepime, ceftriaxone, cefotaxime, cefuroxime, ceftazidime, cefoperazone, metronidazole, meropenem, penicillin G, unasyn, sulperazone, tienam, tazocin, teicoplanin, vancomycin, linez

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    DRUGS NICU Stability

    0.
    Amikacin (Amicin) Dilute (125mg) qs to 25ml NS → 24hrs (5mg/ml)
    250mg/2ml 5mg/ml
    1.
    500mg/2ml

    Amphotericin B 50mg Recons each vial with 10ml WFI. 2-8°C : 7 days
    2. (Photericin B) Take 1ml qs to 50ml D5%→ RT: 24hrs
    2 0.1mg/ml Protect from light

    Azithromycin 500mg Recons 500mg vial with 4.8ml WFI. 2-8°C : 7 day
    (Zithromax) Dilute in 250ml NS/D5. → 2mg/ml
    3.
    3 Azithromycin 500mg Recons 500mg vial with 5ml WFI. 2-8°C : 1 day
    (Azee) Dilute in 250ml NS/D5. → 2mg/ml

    Bactrim 480mg/5ml * Supply undiluted RT: 24hrs


    (Hospira)

    4. Bactrim dose: 480mg/5ml


    4
    TMP dose: 80mg/5ml.

    5. Gentamicin 80mg/2ml Dilute 2ml qs to 40ml NS→ 2mg/ml 24hrs


    5 (Garasent)

    Fluconazole 100mg/50ml Can be used undiluted → 2mg/ml 2-8°C: 7 days


    (Diflucan)
    6.
    6
    Fluconazole 100mg/50ml Can be used undiluted → 2mg/ml 2-8°C: 7 days
    (Flucon)

    Cefepime 1g Add 8.8ml WFI → 100mg/ml 2-8°C : 7days


    7.
    (Megapime)
    9
    8. Cefepime 1g Add 8.8ml WFI → 100mg/ml 2-8°C : 7days
    9 (Vaxcel)

    9. Ceftriaxone1g Add 9.6ml WFI → 100mg/ml 2-8°C : 24hrs


    1 (Oframax)

    10. Cefotaxime 1g Add 10ml WFI → 100mg/ml 2-8°C : 24hrs


    1 (Rekaxime)

    11. Cefuroxime Add 7.5ml WFI → 100mg/ml 2-8°C : 48hrs


    1 750mg

    12. Ceftazidime 1g Add 10ml WFI → 100mg/ml 2-8°C: 24hrs

    13. Cefoperazone 1g RT: 24hrs


    (Bicafar) 2-8°C: 5days

    14. Metronidazole Can be used undiluted → 5mg/ml


    500mg/100ml 2-8°C: 48hrs
    (Metronol)

    15. Meropenem
    1 (DBL Hospira)
    500mg Add 10ml NS. Then qs to 50ml NS RT: 8hrs
    → 10mg/ml F: 24hrs

    1g Prepared in at least
    Add 20ml NS. Then qs to 100ml NS 10ml syringe.
    → 10mg/ml
    Meropenem
    (Meronem)
    RT: 8hrs
    500mg Add 10ml NS. Then qs to 50ml NS F: 48hrs
    → 10mg/ml

    1g Prepared in at least
    Add 20ml NS. Then qs to 100ml NS 10ml syringe.
    → 10mg/ml
    16. Penicillin G 5MIU (3g) Add 10ml WFI. Then qs to 50ml NS 2-8°C : 6Days
    → 100,000iu/ml RT: 2 Days
    17. Unasyn 1.5g Add 3.2ml WFI. Then qs to 50ml NS <30mg/ml in NS
    1 (Karnataka antibiotics) → 30mg/ml F: 72hours
    RT: 8hours
    18. Sulperazone 1g (Pfizer) Add 3.4ml D5% then qs to 50ml → 24hrs
    1 20mg/ml.

    19. Tienam Recons each 500mg vial with 10ml RT: 4hrs
    2 (imipenen+Cilastatin) NS. Dilute in 100ml NS → 5mg/ml 2-8°C : 24hrs
    500mg (MSD)
    20. Tazocin 4.5g (Tazpen) Add 20ml WFI then take 5ml qs to RT: 4hrs
    (Piperacillin sodium 50ml NS  2-8°C : 24hrs
    4000mg + Tazobactam
    sodium 500mg) 22.5mg/ml
    (Tazocin dose)

    20mg/ml
    (Piperacillin Dose)

    21. Teicoplanin 200mg Recons with 3ml WFI.  24hrs


    2 100mg/1.5ml

    22. Vancomycin 500mg Add 10ml WFI. Then take 1ml qs to Recon: (2-8°C)
    2 (USP, Hospira) 10ml D5% → 5mg/ml 14 days
    Diluted: (2-8°C)
    4 days
    23. Linezolid 600mg/300ml Can be used undiluted → 2mg/ml 2-8°C : 1 days
    2 (Zyvox, Pfizer) Protect from light

    24. Caspofungin 70mg/ml 2-8°C : 48 hrs


    2 (Cancidas)
    Do Not shake

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