A Case Study About Nephrotic Syndrome: Our Lady of Fatima University Valenzuela City College of Nursing
A Case Study About Nephrotic Syndrome: Our Lady of Fatima University Valenzuela City College of Nursing
Valenzuela City
College of Nursing
A case study
about
NEPHROTIC SYNDROME
Submitted to:
Prof. Evangeline Serilla Salas MAN, RN, RM
Submitted by:
Lariosa, Ainah Francesca
Lopez, Lyden Blaire
Maac, Katrina
Magsakay, Grace Ann
Malacas, Ma. Kristina
Malaga, Shirly
Marzan, Joshua
GROUP 3E
OUR LADY OF FATIMA UNIVERSITY
Valenzuela City
College of Nursing
I. Learning Objectives
This case study aims to broaden the students’ knowledge and develop their skills and attitude in
the care of clients with Nephrotic Syndrome, learners will:
● Understand the disease process, diagnostic criteria, and pathophysiology of Nephrotic
Syndrome and describe the treatment and management of the patient.
● Apply the nursing process to the care of clients with Nephrotic Syndrome. Set
measurable and achievable short- and long-range goals
● Establish appropriate nursing diagnosis based on the assessment data gathered.
● Provide proper interventions to meet the health needs of the client.
● Formulate and present drug studies of medications given to the client as a part of
treatment regimen.
● Provide appropriate recommendations for the patient's continued recovery.
II. Introduction
Nephrotic syndrome is a sign that
kidneys are not working right.
Nephrotic syndrome has high levels of
protein in urine, low levels of protein in
the blood, and high cholesterol.
Nephrotic syndrome is not a disease. It
is a warning that something is
damaging the kidneys. Without
treatment, that problem could cause
kidney failure, so it's important to get
treatment right away. There are tiny
blood vessels in the kidneys that filter
waste and extra water from the blood.
When these filters are damaged, it can
cause nephrotic syndrome. Protein
helps move water from the tissues into
the blood. Healthy kidneys keep the
right amount of protein in the blood. Damaged kidneys let protein slip from the blood into the
urine. Without enough protein in the blood, fluid builds up in the tissues. This can cause swelling.
Many things can cause this blood vessel damage, including diabetes, lupus, infection, certain
cancers, and some medicines. The most common early symptoms of nephrotic syndrome, in both
children and adults, is swelling in the tissues around the eyes or in the feet or ankles. It may also
have swelling in the lungs that can make it hard to breathe. But many people who have nephrotic
syndrome don't have symptoms. Treatment for nephrotic syndrome depends on the cause and the
age of the person who has the condition. Medicines, changes in diet, and care for other
conditions. These treatments may reverse, slow or prevent further kidney damage.
OUR LADY OF FATIMA UNIVERSITY
Valenzuela City
College of Nursing
Nephrotic syndrome is uncommon, but it plays an important role in the development of kidney
disease. The illness affects roughly 3 adults per 100,000 people per year. According to reports, the
incidence of minimum change illness in children is 2 per 100,000 (Yolanda Smith, 2021).
Severe swelling (edema), particularly around the eyes and in the ankles and feet, is one of the
signs and symptoms of nephrotic syndrome. Foamy urine is caused by an overabundance of
protein in your urine. Weight increase as a result of fluid retention.
Name: R.D.L
Sex: Female
Nationality: Filipino
- No foul ordor
- No masses
- No tenderness
- No discharges
- No swelling/redness
- No discharges
- No watery discharges.
- No palpable nodules
- No retraction
relax and expand to store urine, and contract and flatten to empty
urine through the urethra. The typical healthy adult bladder can
store up to two cups of urine for two to five hours. Specific
landmarks of the bladder are identified upon examination in order
to elucidate presence of irregularities. The trigone is the
triangle-shaped region proximal to the junction of the urethra and
the bladder, it is enclosed by the right and left lateral walls, and the
posterior wall as well as the dome. The sphincter muscles of the
urinary system aid in maintaining the formed urine from leaking
while the nerves found in the bladder predict the time of
micturition process, the contraction of the detrusor muscle and
relaxation of the internal and external urethral sphincter.
Afterwards, the urethra, distal portion of the urinary tract, allows
the urine to be excreted from the body.
OUR LADY OF FATIMA UNIVERSITY
Valenzuela City
College of Nursing
VI. Pathophysiology
OUR LADY OF FATIMA UNIVERSITY
Valenzuela City
College of Nursing
DIAGNOSTIC TESTS:
➢ CBCPC
➢ Serum electrolytes
➢ ASO
➢ BUN
➢ Blood Typing
➢ Coomb’s test
➢ Reticulocyte count
➢ Lipid profile
➢ Albumin
➢ Creatinine
➢ KUB UTZ.
REFER:
➢ Pedia nephrotomy
➢ Hematology
6 doses.
10: 30 PM
➢ Monitor BP every 3 minutes ➢ Monitored BP q30 mins
➢ Furosemide 38 mg TIV ➢ Administered
medication
MEDICATIONS:
➢ Prednisone 20 mg per tab every
after meal. ➢ Administered
➢ Nifedipine 10 mg/capsule. medications
Nutritional and Metabolic The patient has a good The patient is placed under a
Pattern appetite. She usually eats 3 low salt and low fat diet that
meals a day with snacks in affects her appetite. However,
between. She loves to eat with the help of her mother,
carbohydrates rich food like she was still able to eat 3
pizza and fries, as well as meals in a day.
sweetened bananas.
Elimination Pattern The patient has a normal The patient defecated once
bowel pattern and usually and had a urine output of 400
defecates once a day. ml for 8 hours.
However, last December 5 the
patient urinated a tea-colored
urine.
Activity - Exercise Pattern The patient does not really The patient was not able to do
perform exercises, but she any physical activity as she
frequently dances. seems weak and needs
assistance every time she
does something. She is
usually lying down and
sometimes sits in the
monobloc beside her bed.
Sleep - Rest Pattern She usually sleeps 7 to 8 Her sleep and rest periods are
hours a day. usually interrupted with
nurse's rounds because her
vital signs need to be
monitored every 1 hour.
Cognitive - Perceptual The patient did now show any Her cognitive and mental
Pattern signs of cognitive capabilities remained intact.
dysfunctions and can freely
communicate with the nurses.
Self-concept Pattern She believes that the medical Her major concern is to be
OUR LADY OF FATIMA UNIVERSITY
Valenzuela City
College of Nursing
Role Relationship Pattern She has two brothers and a Due to the hospital's policy,
twin sister, whom she only her mother was able to
considers her best friend. accompany her and take good
care of her.
Sexual-Reproductive She had not yet reached She had not yet reached
Pattern menarche. menarche.
Coping or Stress Tolerance The patient talks to her The patient expresses her
mother whenever she is concerns to her mother and
anxious and seeks comfort diverts her attention watching
from her as well. random videos on social
media
Value and Belief Pattern Their family usually goes to The patient prays at night for
church and attends the mass her faster recovery
every sunday.
suggest hemodialysis in
the future.
FUROSEMIDE
MECHANISM OF INDICATION/RA CONTRAINDICA NURSING
DRUG ADVERSE EFFECT
ACTION TIONALE TION CONSIDERATIONS
Form:
Solution for
Injection (ampule)
Route of
Administration:
I.V
AMLODIPINE
MECHANISM OF INDICATION/RAT CONTRAINDICATI NURSING
DRUG ADVERSE EFFECT
ACTION IONALE ON CONSIDERATIONS
Frequency:
OD
Form:
Tablet
Route of
Administration:
PO
PREDNISONE
DRUGS MECHANISM INDICATION/RATI CONTRAINDIC ADVERSE NURSING
OF ACTION ONALE ATION EFFECTS CONSIDERATIONS
● CNS -
● Generic Reduces Patient manifested a restlessness, ● Administer in the
Name: inflammation serious systemic headache, morning, after
Prednisone by reversing disease, this is ● Hypersen dizziness meal of the patient
directed to reducing sitivity to ● GI - dry ● Monitor for blood
● Therapeutic increased
proteinuria and drug mouth, pressure
Class: Anti capillary nausea, ● Monitor for
edema of the ● Active
inflammatory permeability in patient. vomiting cushingoid and
, cells. untreated ● Respiratory adrenal
Immunosuppr Suppresses infection - cough, insufficiency
essant immune system wheezing symptoms
All are not
● Pharmacolo by reducing
manifested by the
gic Class: lymphatic
patient.
Corticosteroi activity.
d
● Dosage:
20mg
● Frequency:
TID
● Form: Tablet
● Route of
Administrati
on: PO
AMPICILIN
DRUGS MECHANISM OF INDICATION CONTRAINDIC SIDE EFFECTS NURSING
ACTION ATION CONSIDERATIONS
Frequency:
Q6
Route of
Administration:
IV
NIFEDIPINE
MECHANISM OF NURSING
DRUGS ACTION INDICATION CONTRAINDICA SIDE EFFECTS CONSIDERATIONS
TION
Generic Name: Nifedipine is a Nifedipine is used Nifedipine is CNS: headache, ● Monitor patient
Nifedipine Calcium channel to manage high contraindicated in dizziness, fatigue, carefully (BP, cardiac
blocking agent that blood pressure. It patients who are nervousness, sleep rhythm, and output)
Brand Name: selectively blocks lowers blood allergic to disturbances. ● Teach significant
Procardia ion influx across pressure by nifedipine. others of the patient
cell membranes of relaxing the blood CV: peripheral edema, the common side
Therapeutic cardiac muscles and vessels so the heart angina, hypotension, effects of the drug
Class: vascular smooth does not have to arrhythmias, and to report any
Anti-Hypertensive muscle without pump as hard severe effects at
changing serum Dermatologic: once.
Pharmacologic calcium Flushing, rash, pruritus, ● Ensure that the
Class: concentrations. dermatitis patient does not chew
-Calcium channel or divide
blocker GI: nausea, sustained-release of
-Antiarrhythmic Constipation, diarrhea, tablet.
-Vasodilator cramps, flatulence
Route of
Administration:
Oral Route
Nursing Care Plan 1
5. Daily
5. Weigh the body
patient daily by weight is
using the same the best
weighing scale indicator
and clothing. of fluid
status.
6. To reduce
6. Instruct the the dryness
parent to of mouth
provide and
frequent oral membrane
hygiene. s.
7. Advise the 7. To
parent to limit regulate
the fluid intake the
as ordered. patient’s
fluid
balance.
Fluid
restriction
is advised
and
indicated
for patients
with
edema.
8. To help
8. Encourage regulate
patient to fluid
consume a low balance
salt, low fat and reduce
and high fluid
potassium. retention.
9. To help
mobilize
9. Encourage the edema
bed rest for a and
few days and prevent
assist in thrombose
ambulation s and
after few days elevation
of medications. of venous
return.
Dependent
Interventions:
DEPENDENT:
A. Amlodipine
Independent: Independent:
Objective: Risk for Hypoproteinemia Short term: After 1 hour of
infection 1. Establish 1. To gain trust rendering nursing
- Changes related to ↓ After 1 hour of rapport with and intervention, the
in vital inadequate rendering the patient confidence in patient and mother
signs defenses and Decreased proteins in nursing and mother. giving care to was able to
treatment of the blood intervention, the the patient. demonstrate
- V/S immunosuppr patient and understanding
taken as essants ↓ mother will be regarding
follows: able to 2. Monitor importance of
Risk for infection demonstrate and reported 2. Monitoring early recognition
T: 36.2 understanding any signs for the sign of infection as
regarding the and and evidenced by
BP: 147/86 importance of symptoms symptoms of verbalizing the
early recognition of infection. the body is signs and
RR: 20 of infection as essential to symptoms of
evidenced by communicate infection.
PR: 82 verbalizing the health
signs and problems and
O2: 100 symptoms of trigger the
infection. search for Long term:
- solution.
Laboratory Long term After 1 week of
result: consistent nursing
T. Protein: 51.9 After 1 week of intervention, the
– LOW consistent patient was able to
nursing 3. Monitor 3. Fever is not develop
WBC: 2.40 intervention, the vital signs often the first infection as
x10^9/L - LOW patient will not especially sign of an evidenced by
develop temperature. infection. A absence of signs
infection as temperature and symptoms of
evidenced by of up to 38º C infection by
absence of signs may indicate maintaining
and symptoms of infection; a temperature in
infection. very high normal range and
temperature breath sounds are
accompanied clear bilaterally.
by sweating
and chills
may indicate
septicemia. GOALS ARE
PARTIALLY
MET.
4. Maintain
and advised 4. Aseptic
the patient’s technique
family to decreases the
practice chances of
medical transmitting
aseptic or spreading
technique pathogens.
and This also
handwashin interrupts the
g before chain of
giving care infection.
to the Handwashing
patient. is the most
common and
simplest way
to maintain
asepsis.
5. Maintain a 5. To avoid
warm and chills and
comfortable susceptibility
environment to URTI.
by
regulating
the room
temperature
and
humidity.
7. Advise
parent and
child to 7. To prevent
avoid the spread of
exposure to microorganis
persons with m and
exposure or provides
share a understandin
room with g of
children free susceptibility
from to infections.
infections.
Dependent
Interventions:
1. Administere 1. Prednisone is
d an
prednisone immunosuppr
20 mg TID essant which
PO as helps to
ordered. prevent
inflammation
but can
reduce ability
of the body to
fight
infections.
2. Administere 2. Ampicillin is
d ampicillin an antibiotic,
750 mg q6 this will
IV as prevent
ordered. infection
formation.
DISCHARGE PLANNING
Medications
○ Amlodipine 5mg OD
○ Prednisone 20 mg TID
○ Nifedipine 10mg/Tab q6, PRN
Environment / Exercise ● Advised the mother to walk with the child at least 10 - 20 minutes.
● Moderate-intensity exercises may be effective and safe for pediatric patients with nephrotic
syndrome in the acute phase.(like dancing, walking.) Exercise therapy may be beneficial to
improve physical function and prevent decline during hospitalization in pediatric nephrotic
syndrome patients.
Treatment ● Steroid treatment can generally manage the symptoms of nephrotic syndrome. Most children with
nephrotic syndrome respond well to steroids and are not at risk of kidney failure.
● Advised the mother that follow-up care is a key part of her child's treatment and safety
Health Teaching
● Wash your hands often, especially before eating and after being in public places.
● Follow your doctor's advice for the amounts of protein and potassium you need in your diet.
● Advise the mother to take all the medications that are prescribed by the physician.
● Advice the mother that her child should take a low salt and low fat diet.
Diet
Be aware of and try to limit the “Salty Six”, which include:
○ Breads, rolls, bagels, flour tortillas, and wraps.Cold cuts and cured meats.
○ Pizza.
○ Poultry (much poultry and other meats are injected with sodium. Check the Nutrition
Facts for sodium content or read the package for a description of a solution, for example,
"Fresh chicken in a 15% solution.")
○ Soup.
○ Sandwiches
● Limit fluid intake
● Keep track of how much fluid your child drinks.
● Advise the mother that her child can eat fresh or frozen vegetables (green beans, lettuce,
tomatoes), low-sodium canned vegetables, and potatoes.
Spiritual Encourage the mother to give full support to the child and to stay by her side. Encourage the significant
others to pray. Remind her to seek protection from God.
References:
Enawgaw, B., Workineh, Y., Tadesse, S., Mekuria, E., Addisu, A., & Genetu, M. (2019).
Iorember, F. (2016, December 21). Anemia in nephrotic syndrome: approach to evaluation and
treatment. SpringerLink.
https://link.springer.com/article/10.1007/s00467-016-3555-6?error=cookies_not_supporte
d&code=b76398b4-e9ea-4264-9640-8031047125f3
Li, P., Yin, Y. L., Li, D., Woo Kim, S., & Wu, G. (2007). Amino acids and immune function.
https://www.hopkinsmedicine.org/health/conditions-and-diseases/nephrotic-syndrome
https://www.nhs.uk/conditions/nephrotic-syndrome/
https://my.clevelandclinic.org/health/body/22506-renin
Sickle cell anemia - Symptoms and causes. (2022, March 9). Mayo Clinic.
https://www.mayoclinic.org/diseases-conditions/sickle-cell-anemia/symptoms-causes/syc
-20355876
Wang, C. S., & Greenbaum, L. A. (2019). Nephrotic Syndrome. Pediatric Clinics of North