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Medical Management/Drug Study

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MEDICAL MANAGEMENT/DRUG STUDY

DRUG NAME DOSAGE, MECHANISM OF INDICATIONS, NURSING RESPONSIBILITIES


ROUTE, ACTION CONTRAINDICATIONS,
FREQUENCY ADVERSE REACTIONS
Brand Name: Via nebulizer 2.5- Mechanism of Action Indication: 1.Assess lung sounds, PR and
Ventolin 5 mg, up to 4 Salbutamol nebuliser BP before drug administration
Nebules times daily It relieves nasal solutions are indicated and during peak of medication.
congestion and for use in the routine
alternatively, may
Generic Name: reversible bronchospasm
e given management of chronic 2.Observe fore paradoxical
Salbutamol by relaxing the smooth
continuously at bronchospasm unresponsive spasm and withhold medication
muscles of the
rate of 1-2 mg/hr. bronchioles. The relief to conventional therapy, and and notify physician if condition
from nasal congestion in the treatment of acute occurs.
and bronchospasm is severe asthma. Adults
made possible by the (including the elderly): 2.5 3.Administer PO medications
following mechanism that mg to 5 mg salbutamol up to with meals to minimize gastric
takes place when four times a day. irritation.
Salbutamol is
administered. 4.Extended-release tablet
 First, it binds to the  To control and prevent should be swallowed-whole. It
beta2-adrenergic reversible airway should not be crushed or
receptors in the airway obstruction caused by chewed.
of the smooth muscle asthma or chronic
which then leads to obstructive pulmonary 5.If administering medication
the activation of the disorder (COPD) through inhalation, allow at
adenyl cyclase and  Quick relief for least 1 minute between
increased levels of bronchospasm inhalation of aerosol
cyclic- 3’5’-adenosine  For the prevention of medication.
monophosphate exercise-induced
(cAMP). bronchospasm 6.Advise the patient to rinse
 When cAMP
 Long-term control agent mouth with water after each
increases, kinases are for patients with chronic inhalation to minimize dry
activated. or persistent mouth.
 Kinases inhibit the
bronchospasm.
phosphorylation of 7. Inform the patient that
Contraindication: Albuterol may cause an unusual
myosin and decrease
intracellular calcium. or bad taste.
Contraindicated in patients
 Decreased in with high blood pressure
intracellular calcium will during pregnancy, uterine
result to the relaxation infection, miscarriage, heart
of the smooth muscle disease, and

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