DM - Notes
DM - Notes
DM - Notes
Diabetes Mellitus
Why C peptide is used as marker for insulin secretion rather than insulin?
- Measurement of C-peptide can be used to assess endogenous
insulin secretory capacity , C-peptide negativity (indicating complete
insulin deficiency) , and it is not metabolized by liver .
What is HbA1c?
- Glucose in the blood will react with the terminal valine of the
haemoglobin molecule to produce glycosylated haemoglobin
(HbA1c). The percentage of HBA1c is a good indicator of how
effective blood glucose control has been. As RBCs normally spend
~3 months in the circulation the %HbA1c is related to the average
blood glucose concentration over the preceding 2-3 months.
- Poorly controlled diabetics can have a HbA1c value above 10%.
- Hemoglobin A1c (%) : normal ( ≤5.6 ) , pre-diabetes ( 5.7-6.4 ) , DM
: ( ≥6.5 )
Endocrine, DM and renal Care Block 3
What are the indications for use of aspirin and statin in diabetic patients?
- the use of aspirin for secondary prevention of coronary events and
the consideration of aspirin use in diabetic individuals with an
4 Endocrine, DM and renal Care Block