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Antiemetic Drug Questions Bank

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Community pharmacy & OTC

Constipation
Model answers:
1 2 3 4 5 6 7 8 9 10
e d b a d a b e c a
11 12 13 14 15 16 17 18 19 20
c b e e c a b a b c

1) The most effective antiemetic drug in motion sickness is


a) Lorazepam d) Ergotamine
b) Tetrahydrocannabinol e) Dimenhydrinate
c) Acetaminophen

2) All of the following are adverse effects of anticholinergic drugs except


a) Blurred vision d) Excessive salivation
b) Tachycardia e) Drowsiness
c) Dry mouth

3) Nausea and vomiting are common in the first trimester of pregnancy due to high blood
level of
a) Progesterone d) Growth hormone
b) Estradiol e) Adrenaline
c) Testosterone

4) Dexamethasone is more effective as antiemetic when combined with


a) Dopamine antagonists and 5HT3 antagonists d) Bismuth salts
b) Tetracycline e) All of the above
c) Laxatives

5) Ondansetron is
a) Anticholinergic drug d) 5-HT3 selective antagonist drug
b) Benzodiazepine drug e) Cannabinoid drug
c) Dopamine antagonist drug

6) All of the following are adverse effects of corticosteroids except


a) Hypoglycemia d) Cushing syndrome
b) Osteoporosis e) Peptic ulcer
c) Increased susceptibility to infection

7) The extrapyramidal side effects can occur with


a) Scopolamine d) Dexamethasone
b) Metoclopramide e) Doxylamine
c) Meclizine

8) Nausea and vomiting may occur due to CNS related condition such as:
a) Stroke d) CNS toxic agents
b) Meniere's disease e) All of the above
c) Increased intracranial pressure

9) Nausea and vomiting can occur due to all of the following except:
a) Cisplatin d) Cardiac glycosides
b) Methotrexate e) Bacterial toxins
c) Domperidone

10) which one of the following drugs may lead to tachycardia:


a) Scopolamine d) Domperidone
b) Lorazepam e) Alprazolam
c) Dexamethasone

11) Metoclopramide is
a) Beta blocker d) Anticholinergics
b) Alpha blocker e) Anti cox ІІ inhibitors
c) D2 selective antagonists

12) Nabilone is one of :


a) Corticosteroids d) Anticholinergics
b) Cannabinoids e) Benzodiazepines
c) Dopamine antagonists

13) The most common adverse effect of 5HT3 antagonists all of the following except:
a) Constipation d) Dizziness
b) Headache e) Hyperglycemia
c) Diarrhea

14) Increased Susceptibility to infection is the most common adverse effect of :


a) Lorazepam d) Tetrahydrocannabinol
b) Scopolamine e) Corticosteroids
c) Granisetron
15) Which one of the following drugs may lead to dry mouth:
a) NSAIDs d) Warfarin
b) Dexamethasone e) Aspirin
c) Dimenhydrinate

16) All of the following drugs have antihistaminic effect except:


a) Magnesium hydroxide d) Doxylamine
b) Meclizine e) Diphenhydramine
c) Dimenhydrinate

17) The sequence of events in the act of vomiting includes:


a) Hiccup, retching and vomiting d) Bloating and vomiting
b) Nausea, retching and vomiting. e) anosmia and vomiting
c) Sneezing, hiccup and nausea

18) Retching means:


a) Reverse of movement of esophagus and stomach d) Reverse of movement of stomach and duodenum.
b) Reverse of movement of ascending colon e) Reverse of movement of gastroesophageal junction.
c) Normal peristalsis of the small intestine

19) Lorazepam stop vomiting by


a) Direct effect on gastric wall d) decrease acid production in the stomach
b) Prevent central cortical induced vomiting e) increase production of digestive enzymes.
c) Increasing peristalsis of the intestine

20) which one of the following drugs better to be avoided in diabetic patient:
a) Ondansetron d) Metoclopramide
b) Lorazepam e) Domperidone
c) dexamethasone

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