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QuickVet® COAG™ PT/aPTT Combo™ Test

QuickVet® COAG™PT/aPTT Combo™

The one and only Prothrombin Time (PT) & Activated Partial
Thromboplastin Time (aPTT) combination test available

· In clinic use - Test results at the patient side

· Fast and convenient - Test time less than 15 min
· No sample preparation - Uses whole citrated blood
· Multi species - Works with both Canine and Feline samples
· Ease of use - 3 easy and fast steps to get a result
· Accurate reliable results - Test precision < 7 % CV
· State of the art - Capillary driven microfluidic technology

Diagnose bleeding disorders immediately

The QuickVet® COAG™ PT/aPTT Combo™ Test aids in the diagnosis of excessive
bleeding, hereditary bleeding disorders, toxins and systemic diseases, rodentacide
poisoning, pre-surgical work up, disseminated intravascular coagulopathy (DIC),
and possible anemia.
Citrate aPTT
Citrate PT The cartridge is designed to perform blood coagulation tests using citrate
For veterinary use only.
For use with citrated stabilized whole blood. The test simultaneously measures the Prothrombin
whole blood only.
Time (PT) and the Activated Partial Thromboplastin Time (aPTT) giving the
veterinarian fast and valuable information on the functionality of the blood
Citrate PT
coagulation cascade.
For veterinary use only.
For use with citrated
whole blood only.
How to perform a test
Three simple and fast steps are all you need to perform a QuickVet® COAG™
Citrate aPTT
PT/aPTT Combo™ Test in the clinic: Collect a blood sample 4 add sample to
For veterinary use only.
For use with citrated cartridge 4 read result.
whole blood only.

QuickVet® test cartridge

Each QuickVet® cartridge
It takes less than 15 min to perform the test. The actual time depends on the
representing state-of-the-art sample and ambient temperature where testing. Test results obtained under
technology has a label stating normal operating conditions have a CV (Coefficient of Variation) of 7 % or less.
what kind of test the cartridge
All clotting times are reported in seconds.
performs, a sample well for adding
the whole blood sample, several
micro channels and two optical Performance
detection windows. The QuickVet® instrument and the COAG™ PT/aPTT Combo™ Test has in
collaboration with the Small Animal Hospital at Copenhagen University been
validated for Canine and Feline use. The product enables testing of whole
citrate stabilised blood with a hematocrit as low as 15 % on both Canine and
Feline samples.
www.quickvet.net F o r Ve t e r i n a r i a n s o n l y

Coagulation
Blood coagulation is the process by which blood forms clots. Disorders in the coagulation process can lead to
an increased risk of bleeding and/or clotting. Events that lead to the formation of a blood clot are simplified in
coagulation theory into two coagulation cascades that are referred to as the intrinsic pathway and the extrinsic
pathway, both leading to the common pathway and the formation of a stable fibrin clot.

A suggested coagulation protocol

The analysis of blood coagulation can be a guide in determining a large number of existing or potential disorders
that can seriously impact the health of the patient.

aPPT
Prolonged Normal

PT PT

Prolonged Normal Prolonged Normal

Common pathway disorder No coagulation disorder

± combined intrinsic and Intrinsic pathway disorders Extrinsic pathway disorders due to deficit in
extrinsic pathway disorder coagulation factors

Over-heparinization Hemophilia A (VIII) Factor VII deficiency Consider primary

bleeding disorder
- platelets
DIC Hemophilia B (IX) Early rodenticide - von Willebrand factor
deficiency
- Vascular disorder

Common pathway Hemophilia C (XI)

factor deficiency Vitamin K
deficiency/
antagonist
Vitamin K deficiency/ Factor XII deficiency
antagonist with no associated
bleeding disorder

Rodenticide toxicity

The QuickVet® COAG™ PT/aPTT Combo Test

Each QuickVet® Test cartridge is clearly labelled with the test type and individually
packaged in a sealed pouch with a desiccant. A disposable pipette is supplied
with each cartridge.

• For use with the QuickVet® Analyzer

TT
te aP • Use on both Canine and Feline samples
C i t ra t e P T
C i t ra ly.
se on • Practical one time use only cartridge
ary u
eterin h citrated
For v
se wit
For u blood on
ly. • No cleaning or regular maintenance required
whole
• Results in less than 15 min
te PT • Handles samples with hematocrit between 15-55 %
C i t ra
ary u
se on
ly. • Test precision equal or better than 7 % CV
eterin h citrated
For v
For u se wit
blood
o n ly.
• 1 year shelf-life on cartridges
whole

TT
te aP
C i t ra ly.
se on
ary u
eterin h citrated
For v w it ly.
se
For u blood on
whole

Scandinavian Micro Biodevices ApS

Gammelgaardsvej 87C · DK-3520 Farum · Denmark
Tel.: +45 7020 7303 · Fax: +45 7020 7304
Email: info@smb.dk · Website: www.smb.dk