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Alteco LPS - Brochure

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Removing the threat. Removing endotoxin rapidly stabilizes the patient.

The device produces rapid results when required and usually only one treatment is needed.
The Alteco® LPS Adsorber removes endotoxin safely, effectively The optimized blood contact area reduces immune activation. It rapidly stabilizes the patient
and easily in both acute and planned situations. by removing the endotoxin and is a positive tool for helping the immune system to act on
its own.

The Alteco LPS Adsorber is a unique, proven medical device that removes endotoxin
(Lipopolysaccharides or LPS) from the blood system through extracorporeal treatment. This
innovative device, created by using advanced Swedish technology, is safe and completely
non-toxic with no reported side effects. It is being used in the successful treatment of a
various patient groups with high levels of endotoxin, from critical patients with gram-negative a. PE-discs (PE surface with pores).
sepsis to scheduled cardio-surgery patients. b. Pore in PE surface (size: 100 micron) - Showing LPS
capturing by the peptides. The cationic peptides are
covalently immobilized onto the PE- discs. During
The adsorber is quick to prepare and easy to use, which is crucial in critical situations. The treatment the cationic part of the peptide captures the
process is effective without requiring extra investment and has a rapid onset of action. b negatively charged endotoxin molecules.

When used in an early setting it can be a lifesaver and should be used as a proactive tool to
avoid life-threatening situations by preventing organ failure caused by endotoxin, paving the
way for successful treatment.

The device delivers rapid results and usually only one treatment is needed. The optimized
blood contact area reduces immune activation. It rapidly stabilizes the patient by removing
the endotoxin and is an effective tool for helping the immune system to act on its own.
Cationic peptide
High levels of endotoxin are associated with organ failure and death. Therefore, the sooner
Endotoxin (LPS)
treatment is started the better it is. Having an Alteco LPS Adsorber close at hand guarantees
that treatment will be quick, effective and easy.

When endotoxin is a threat or a problem, then the Alteco LPS Adsorber is the solution.

Endotoxin, or lipopolysaccharides (LPS), is one


of the major components of the cell membrane O-antigen
in gram-negative bacteria.

When the bacteria are lysed the endotoxin is Core Polysaccharide


exposed. A secondary endogenous source
of endotoxin is epithelial barrier dysfunction Lipid A
– Glucosamine
in the gut.
– Fatty Acids
Treatment Data Dimensions and Weight
Rinsing: 500 ml 0.9 % saline Length: 135 mm
Priming: 0.9 % saline solution with heparin Outer diameter: 52 mm
Blood flow, hemoperfusion: 150 ± 50 ml/min Net weight: ~ 130 g
Recommended treatment time: 2-6 hours

Order Information
Product Specification Product name: Alteco® LPS Adsorber
Adsorber volume: 100 ml Product reference number: LPS-33-100-46
Housing: Acrylic polymer Developer and manufacturer: Alteco Medical AB
End caps: Acrylic polymer Höstbruksvägen 8
Matrix (porous plates): Polyethylene 226 60 Lund
Active component: Peptide (100 % synthetic) Sweden
Sterilisation: Radiation (e-beam) sales@altecomedical.com
Expiration time: 3 years www.altecomedical.com
Inlet/outlet connectors: Standard dialysis

Alteco® is a registered trademark of Alteco Medical AB.


The Alteco® LPS Adsorber is based on technology for
Regulatory Information which patents have been granted in the EU, China (PRC),
Product registration: ~ 30 countries around the world Russia, USA, etc. The product is bar-coded according to
Classification: Medical Device, Class IIa GTIN-13. Not for sale in the US.
ISO certificate: ISO 13485

Easy to set up
- Easy to use

Alteco Medical AB • Höstbruksvägen 8 • SE-226 60 Lund • Sweden


Tel +46 (0)46-32 86 00 • Fax +46 (0)46-14 86 50 • info@altecomedical.com altecomedical.com

© Alteco Medical AB 2019. All rights reserved. Alteco is a registered trademark. • BR01 Main folder 190909EN

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