DRUG STUDY

Name of the Patient: Darwin Maximo Age: 47 Sex: M Name of Student: __

Civil Status: Married____ Religion: Rm/Bed No. 214_ Area: _________ Level/ Block: __________
Address: Date Submitted: _ ___________
Date of Admission: Oct 8, 2022 _ Diagnosis: __ Rating: _________________________________

MEDICATION Classification/ Action Indications Contraindications Side Effects Adverse Effects Nursing Responsibilities

Generic name: CLASSIFICATION Tramadol Frequent (25%– Seizures reported in pts  May cause physical
hydrochloride 50 15%): Dizziness, receiving traMADol within dependence.
tramadol Pharmacotherapeutic: Centrally Treatment mg/ml solution for vertigo, nausea, recommended dosage  Pts with history of drug abuse
acting synthetic opioid. of moderate constipation, range.
Brand name: injection or are at increased risk for
to severe headache,
infusion is drowsiness. serotonin syndrome misuse or abuse. Take
tramadol pain. contraindicated (agitation, hallucinations, medication only as
Clinical: Analgesic Occasional (10%– tachycardia, prescribed.
Usual dosage/ - in patients who 5%): Vomiting, hyperreflexia).  Avoid alcohol, other
frequency have previously pruritus, CNS narcotics, sedatives.
shown stimulation (e.g., May cause suicidal
IV Side drip: Adult: 50- ACTION: Binds to mu-opioid  May cause drowsiness,
hypersensitivity to nervousness, ideation
100 mg 4-6 hourly via receptors in CNS, inhibiting anxiety, agitation, and behavior. dizziness, blurred vision.
the active
slow IV over 2-3 ascending pain pathway. tremor, euphoria,  Avoid tasks requiring
substance
minutes, IM, or SC inj. Inhibits reuptake of mood swings, Significant: Sleep-related alertness, motor skills until
tramadol.
Max: 600 mg daily. norepinephrine, serotonin, hallucinations), breathing disorders response to drug is
inhibiting descending pain - in patients asthenia, convulsions, reversible established.
Usual route pathways. diaphoresis, adrenal insufficiency,
suffering from  Report severe constipation,
dyspepsia, dry severe hypotension,
Oral acute intoxication mouth, diarrhea. hyponatremia, CNS difficulty breathing, excessive
with alcohol, depression. sedation, seizures, muscle
Therapeutic Effect: Reduces hypnotics, Rare (less than weakness, tremors, chest
 pain. analgesics, Rarely, drug dependence pain, palpitations.
opioids, or 5%): Malaise, (prolonged use) and
Drug order psychotropic vasodilation, abuse; hypoglycemia
medicinal anorexia,
Side drip of D5W 250 Pharmacokinetics flatulence, rash, Cardiac
cc + 200mg Tramadol products. blurred vision, disorders: Palpitations,
regulated @ 5 cc/hr urinary tachycardia.
- in patients who
retention/frequency, Gastrointestinal
Absorption: Rapidly, almost are receiving disorders: Nausea,
menopausal
completely absorbed after monoamine symptoms. vomiting, dry mouth,
administration. oxidase (MAO) constipation, abdominal
inhibitors or who discomfort, dyspepsia.
Protein binding: 20% Nervous system
have taken them
within the last 14
disorders: Dizziness,
Metabolism: Metabolized in drowsiness, headache,
liver (reduced in pts with days tremor.
advanced cirrhosis). Psychiatric
- in patients with
disorders: Anxiety,
Excretion: Primarily excreted in epilepsy not agitation, emotional
urine. Minimally removed by adequately lability, euphoria,
hemodialysis. controlled by hallucinations,
treatment. nervousness.
Half-life: 6-7 hours
- for use in narcotic
withdrawal
treatment.
DRUG INTERACTIONS:

- Alcohol, other CNS

depressants (e.g.,
LORazepam,
morphine, zolpidem)
may increase CNS
depression.
- CarBAMazepine
decreases
concentration/effects.
 - CYP2D6 inhibitors
(e.g., PARoxetine),
CYP3A4 inhibitors
(e.g., clarithromycin,
ketoconazole,
ritonavir), triptans,
selective serotonin
reuptake inhibitors
(SSRIs), tricyclic
antidepressants (e.g.,
amitriptyline, doxepin)
may increase risk of
seizures, risk of
serotonin syndrome.

References: