+1 Bio Zoo em Vol 2
+1 Bio Zoo em Vol 2
+1 Bio Zoo em Vol 2
-: GOD GRACE :-
BIO- ZOOLOGY
( NEW EDITION FOR 2023-2024 )
VOLUME –II
( Included Govt Question paper – March-2023 added )
Prepared by :-
P.SENGUTTUVAN. M.Sc.,M.Ed.,M.Phil. &
C.VALARMATHI. M.Sc.,M.Ed.,M.Phil.
P.G.Teachers-Zoology.
DHARMAPURI-Dist.
Cell : 9865449511.
18. Right ventricular wall is thinner than the left ventricular wall. Why?
The Left ventricle pumps blood into the aorta, which distributes pure blood to all parts of body.
But Right ventricle pumps blood into the pulmonary artery which carry blood to the lungs only.
So the wall of the right ventricular thinner than the left vetricular wall.
20. Describe the mechanism by which the human heart beat is initiated and controlled. OR
Origin and Conduction of Heart Beat :- (March -2023)
22. What are the heart sounds? When and how are these sounds produced?
HEART BEAT- Rhythmic contraction and expansion of heart is called heart beat.
The contraction of the heart is called systole and the relaxation of the heart is called diastole.
The heart normally beats 70-72 times per min in a human adult.
During each cardiac cycle 2 sounds are produced that can be heard through a stethoscope.
P.Senguttuvan.M.Sc., M.Ed.,M.Phil.& C.Valarmathi. M.Sc., M.Ed.,M.Phil. –Dharmapuri.
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1. Lub - is associated with the closure of the tricuspid and bicuspid valves.
2. Dub - is associated with the closure of the semilunar valves.
24. Name and Label the given diagrams to show A,B,C,D,E,F and G
A - Aortic arch
E – Left Ventricle
F – Right Ventricle.
They are colourless, amoeboid, nucleated cells. 6000 to 8000 per cubic mm of WBCs are seen in the blood.
Depending on the presence or absence of granules, WBCs are divided into two types.They are
1. Granulocytes - are presence of granules in the cytoplasm. They are neutrophils, eosinophils and basophils.
i) Neutrophils –
They are 60%- 65% , and also called heterophils or polymorphonuclear,cells with 3-4 lobes of nucleus,
They are phagocytic in nature and appear in large numbers in and around the infected tissues.
ii) Eosinophils –
They are 2-3% , and have bilobed nucleus, and are non-phagocytic.
Eosinophils increase during certain types of parasitic infections and allergic reactions.
iii) Basophils –
They are 0.5%- 1.0% , The cytoplasmic granules are large sized,Nucleus is large sized and constricted
into several lobes, and are secrete substances such as heparin, serotonin and histamines.
They are also involved in inflammatory reactions.
2. Agranulocytes- They are absence of granules in the cytoplasm and of 2 types lymphocytes and monocytes.
i) Lymphocytes –
28% , large round nucleus and small amount of cytoplasm. The two types of lymphocytes are B and T
cells. Both B and T cells are responsible for the immune responses of the body.
B - cells produce antibodies to neutralize the harmful effects of foreign substances.
T - cells are involved in cell mediated immunity.
ii) Monocytes (Macrophages) –
They have kidney shaped nucleus and constitute 1-3% of the total WBCs.
The macrophages are phagocytic cells .
6. Coagulation of blood :-
If get yourself hurt, your wound bleeds for some time after which it stops to bleed. This is because the
blood clots or coagulates in response to trauma.
The mechanism by which excessive blood loss is prevented by the formation of clot is called blood
coagulation or clotting of blood.
The blood vessel is damaged and the connective tissue in its wall is exposed to the blood.
Clotting factors released from the damaged cells mix with clotting factors in the plasma.
The protein called prothrombin is converted to its active form called thrombin in the presence of
calcium and vitamin K.
Thrombin helps in the conversion of fibrinogen to fibrin threads. The threads of fibrins become interlinked
into a patch that traps blood cell and seals the injured vessel.
Schematic representation of blood coagulation is shown Figure:
8. Electrocardiogram (ECG) :-
It records the changes in electrical potential across the heart during one cardiac cycle.
The special flap of muscle which initiates the heart beat is called as sinu-auricular node or SA node in the
right atrium. It spreads as a wave of contraction in the heart.
The waves of the ECG are due to depolarization and not due to contraction of the heart.
This wave of depolarisation occurs before the beginning of contraction of the cardiac muscle.
A normal ECG shows 3 waves designated as P wave, QRS complex and T wave .
1. P Wave (atrial depolarisation)- It is a small upward wave and indicates the depolarisation of the atria. This
is the time taken for the excitation to spread through atria from SA node. Contraction of both atria lasts for
around 0.8-1.0 sec.
2. PQ Interval (AV node delay) - It is the onset of P wave to the onset of QRS complex. This is from the start
of depolarisation of the atria to the beginning of ventricular depolarisation. It is the time taken for the impulse
to travel from the atria to the ventricles (0.12-0.21sec). It is the measure of AV conduction time.
3. QRS Complex (ventricular depolarisation)- Atrial depolarisation occurs simultaneously with the ventricular
depolarisation. The normal QRS complex lasts for 0.06-0.09 sec. QRS complex is shorter than the P wave,
because depolarisation spreads through the Purkinjie fibres.
4. ST Segment - It lies between the QRS complex and T wave. It is the time during which all regions of the
ventricles are completely depolarised . The ST segment lasts for 0.09 sec.
5. T wave (ventricular depolarisation)- It represents ventricular depolarisation. The duration of the T wave is
longer than QRS complex because repolarisation takes place simultaneously throughout the ventricular
depolarisation.
10.Hypertension : -
The normal blood pressure in man is 120/80 mmHg.
In cases when the the systolic pressure exceeds 150 mm Hg and diastolic pressure exceeds 90 mmHg
persistently, the condition is called hypertension.
Uncontrolled hypertension may damage the heart, brain and kidneys.
12. Stroke :-
π It is a condition when the blood vessels in the brain bursts, (Brain haemorrhage) or when there is a block
in the artery that supplies the brain, (atherosclerosis) or thrombus.
π The part of the brain tissue that is supplied by this damaged artery dies due to lack of oxygen.
P.Senguttuvan.M.Sc., M.Ed.,M.Phil.& C.Valarmathi. M.Sc., M.Ed.,M.Phil. –Dharmapuri.
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13. Angina pectoris (ischemic pain in theheart muscles):-
It is experienced during early stages of coronary heart disease.
Atheroma may partially block the coronary artery and reduce the blood supply to the heart.
As a result, there is tightness or choking with difficulty in breathing.
This leads to angina or chest pain. Usually it lasts for a short duration of time.
15. Embolism:-
It is the obstruction of the bloodvessel by abnormal mass of materials such as fragment of the blood clot,
bone fragment or an air bubble.
Embolus may lodge in the lungs, coronary artery or liver and leads to death.
16. Aneurysm:-
The weakened regions of the wall of the artery or veins bulges to form a balloon like sac.
Unruptured aneurysm may exert pressure on the adjacent tissues / may burst causing massive haemorrhage.
8. EXCRETION
BOOK BACK QUESTION & ANSWER
1. b. length of Henle‟s loop 7. c. Blood with proteins but without cells
2. d. The urine will be more dilute 8. d. calcium ixalate
3. a. Micturition will continue 9. c. uricotelic
4. c. urea 10. a. Aquaphorins
+ +
5. d. PCT - Absorption of Na and K ions 11. c. antidiuretic hormone
6. b. Inner wall of Bowman‟s capsule 12. c. haemolymph
13. Arrange the following structures in the order that a drop of water entering the nephron would encounter them.
Answer :-
1) Afferent arteriole
2) Glomerulus
3) Bowman‟s capsule
4) Proximal tubule
5) Loop of Henle
6) Distal tubule
7) Collecting duct
8) Renal pelvis
14. Name the three filtration barriers that solutes must come across as they move from plasma to the lumen of
Bowman‟s capsule. What components of the blood are usually excluded by these layers?
1) Glomerular capillary endothelium – Prevents the blood cells.
2) Basal lamina – Glycoproteins, plasma proteins.
3) Epithelium of bowman‟s capsule.
15. What forces promote glomerular filtration? What forces opposes them? What is meant by net filtration pressure?
Net filtration Pressure = Glomerular hydrostatic pressure - (Colloidal osmotic pressure + Capsular
hydrostatic pressure).
Net filtration pressure = 55 mmHg - (30 mmHg + 15 mmHg) = 10mmHg
The effective glomerular pressure of 10 mmHg results in ultrafiltration.
16. Identify the following structures and explain their significance in renal physiology?
a. Juxtaglomerular apparatus –
The ascending limb of Henle returns to the glomerular region of its own nephron, where it passes through
the fork formed by the afferent and efferent arterioles.
Both the tubular and vascular cells at this point are specialized to form juxta glomerular apparatus that lie
next to the glomerulus.
b. Podocytes –
The glomerular membrane consists of octopus like cells called podocytes that entangles the glomerular tuft.
Each podocyte bears many foot processes.
17. In which segment of the nephron most of the re-absorption of substances takes place?
Reabsorption takes place by the tubular epithelial cells in different segments of the nephron either by
active transport or passive transport, diffusion and osmosis.
Per day nearly 99% of the glomerular filtrate that has to be reabsorbed by the renal tubules as it contains
certain substances needed by the body. This process is called selective reabsorption.
18. When a molecule or ion is reabsorbed from the lumen of the nephron, where does it go? If a solute is filtered
and not reabsorbed from the tubule, where does it go?
i. When a molecule or ion is reabsorbed from the lumen of the nephron, it goes out of – Efferent arteriole.
ii. If a solute is filtered and not reabsorbed from the tubule, it finally reach the collecting duct to be sent out
as waste in the form of urine.
19. Which segment is the site of secretion and regulated reabsorption of ions and pH homeostasis?
The distal convoluted tubule recovers water and secretes potassium into the tubule.
Na+ , Cl - and water remains in the filtrate of the DCT.
Most of the reabsorption from this point is dependent on the body‟s need and is regulated by hormones.
-
Reabsorption of bicarbonate ( HCO3 ) takes place to regulate the blood pH.
-
Homeostasis of K+ and Na in the blood is also regulated in this region.
20. What solute is normally present in the body to estimate GFR in humans ?
Renal clearance is a parameter that reflects the amount of solute passing from the plasma to the urine in a
given period of time.
If the renal clearance is equal to the GFR it means that there is efficient filtration with little reabsorption
and secretion.
It is one of the parameters used to identify the efficiency of the kidney.
21. Which part of the autonomic nervous system is involved in micturation process?
The functioning of kidneys is efficiently monitored and regulated by hormonal feedback control
mechanism involving the hypothalamus, juxta glomerular apparatus and to a certain extent the heart.
Osmoreceptors in the hypothalamus are activated by changes in the blood volume, body fluid volume
and ionic concentration.
22. If the afferent arteriole of the nephron constricts, what happens to the GFR in that nephron? If the efferent
arteriole constricts what happens to the GFR in that nephron? Assume that no auto regulation takes place.
i. If the afferent arteriole of the nephron constricts, what happens to the GFR in that nephron.
- Decrease in GFR.
ii. If the efferent arteriole constricts what happens to the GFR in that nephron – Increase in GFR.
P.Senguttuvan.M.Sc., M.Ed.,M.Phil.& C.Valarmathi. M.Sc., M.Ed.,M.Phil. –Dharmapuri.
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23. Indentfiy the biological term
( Homeostasis, excretion, glomerulus,urea, glomerular filtration, ureters, urine, Bowman’s capsule, urinary
system, reabsorption, micturition, osmosis, glomerular capillaries via efferent arteriole, proteins.)
a. A liquid which gathers in the bladder - urine
b. Produced when blood is filtered in a Bowman‟s capsule - glomerular filtrate
c. Temporary storage of urine – Urinary bladder
d. A ball of inter twined capillaries - glomerulus
e. Removal of unwanted substances from the body - excretion
f. Each contains a glomerulus - Bowman’s capsule
g. Carry urine from the kidneys to the bladder - ureters
h. Scientific term for urination - micturition
i. Regulation of water and dissolved substances in blood and tissue fluid - Homeostasis
j. Consists of the kidneys, ureters and bladder - urinary system
k. Removal of useful substances from glomerular filtrate - reabsorption
l. What solute the blood contains that are not present in the glomerular filtrate? – proteins
With regards to toxicity and the need for dilution in water, how different are ureotelic and uricotelic excretions?
Give examples of animals that use these types of excretion? (March -2023)
Uricoteles Ureoteles
Reptiles, birds, land snails and insects In terrestrial animals, less toxic urea anduric acid are produced
excrete uric acid crystals, with a minimum to conserve water. Mammals and terrestrial amphibians
loss of water and are called uricoteles. mainly excrete urea and are called ureoteles.
29. What vessels carry blood to the kidneys? Is this blood arterial or venous?
i. The vessels carry blood to the kidneys is – Renal artery.
ii. The blood carry to the kidneys is - Arterial blood.
31. What is tubular secretion? Name the substances secreted through the renal tubules ?
+ + +
Substances such as H , K , NH4 , creatinine and organic acids move into the filtrate from the peritubular
capillaries into the tubular fluid.
+
Most of the water is absorbed in the proximal convoluted tubule and Na is exchanged for water in the
loop of Henle.
Hypotonic fluid enters the distal convoluted tubule and substances such as urea and salts pass from
peritubular blood into the cells of DCT.
The urine excreted contains both filtered and secreted substances. Once it enters the collecting duct,
water is absorbed and concentrated hypertonic urine is formed.
+ + +
For every H secreted into the tubular filtrate, a Na is absorbed by the tubular cell. The H secreted
+ - - + +
combines with HCO3 , HPO3 and NH3 and gets fixed as H2CO4 , H2PO4 and NH4 respectively.
+ +
Since H gets fixed in the fluid, reabsorption of H is prevented.
32. How are the kidneys involved in controlling blood volume? How is the volume of blood in the body related
to arterial pressure?
Juxta glomerular apparatus (JGA) is a specialized tissue in the afferent arteriole of the nephron that
consists of macula densa and granular cells.
The macula densa cells sense distal tubular flow and affect afferent arteriole diameter, whereas the
granular cells secrete an enzyme called renin.
A fall in glomerular blood flow, glomerular blood pressure and glomerular filtration rate, can activate JG
cells to release renin which converts a plasma protein, angiotensinogen to angiotensin I.
Angiotensin converting enzyme (ACH) converts angiotensin I to angiotensin II.
+
Angiotensin II stimulates Na reabsorption in the proximal convoluted tubule by vasoconstriction of the
blood vessels and increases the glomerular blood pressure.
Angiotensin II acts at different sites such as heart, kidney, brain, adrenal cortex and blood vessels.
+ +
It stimulates adrenal cortex to secrete aldosterone that causes reabsorption of Na , K excretion and
absorption of water from the distal convoluted tubule and collecting duct.
This increases the glomerular blood pressure and glomerular filtration rate.
This complex mechanism is generally known as Renin- Angiotensin- Aldosterone System (RAAS).
Figure shows the schematic representation of the various hormones in the regulation of body fluid
concentration.
P.Senguttuvan.M.Sc., M.Ed.,M.Phil.& C.Valarmathi. M.Sc., M.Ed.,M.Phil. –Dharmapuri.
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33. Name the three main hormones are involved in the regulation of the renal function?
1) ADH – Antidiuretic hormone.
2) Renin- Angiotensin
3) Aldosterone.
34. What is the function of antidiuretic hormone? Where is it produced and what stimuli increases or decreases its
secretion?
when there is an increase in the blood pressure, the osmoreceptors of the hypothalamus respond by
stimulating the neurohypophysis to secrete the antidiuretic hormone (ADH) or vasopressin (a positive
feedback).
ADH facilitates reabsorption of water by increasing the number of aquaporins on the cell surface
membrane of the distalmconvoluted tubule and collecting duct.
This increase in aquaporins causes the movement of water from the lumen into the interstitial cells,
thereby preventing excess loss of water by diuresis.
When you drink excess amounts of your favourite juice, osmoreceptors of the hypothalamus is no longer
stimulated and the release of ADH is suppressed from the neurohypophysis (negative feedback) and the
aquaporins of the collecting ducts move into the cytoplasm.
Vasopressin secretion is controlled by positive and negative feedback mechanism.
ADDITIONAL QUESTION
1. Ammonoteles :-
Animals that excrete most of its nitrogen in the form of ammonia are called ammonoteles.
Many fishes, aquatic amphibians and aquatic insects are ammonotelic.
In bony fishes, ammonia diffuses out across the body surface or through gill surface as ammonium ions.
2. Structure of kidney :-
Excretory system in human consists of a pair of kidneys, a pair of ureters, urinary bladder and urethra.
Kidneys are reddish brown, bean shaped structures, that lie in the superior lumbar region.
The right kidney is placed slightly lower than the left kidney. Each kidney weighs is120-170 grams.
The outer layer of the kidney is covered by cortex, inner medulla and pelvis.
The medulla is divided into a few conical tissue masses called medullary pyramids or renal pyramids.
The part of cortex that extends in between the medullary pyramids is the renal columns of Bertini.
The centre of the inner concave surface of the kidney has a notch called the renal hilum, through which
ureter, blood vessels and nerves innervate.
Inner to the hilum is a broad funnel shaped space called the renal pelvis with projection called calyces.
The renal pelvis is continuous with the ureter once it leaves the hilum.
The walls of the calyces, pelvis and ureter have smooth muscles which contracts rhythmically.
The calyces collect the urine and empties into the ureter, which is stored in the urinary bladder
temporarily.
The urinary bladder opens into the urethra through which urine is expelled out.
Nephron is the structural and functional unit of kidneys. Each kidney has nearly one million nephron.
Each nephron consists of a filtering corpuscle called renal corpuscle (malpighian body) and a renal tubule.
The renal tubule opens into a longer tubule called the collecting duct.
The renal tubule begins with a double walled cup shaped structure called the Bowman’s capsule, which
encloses a ball of capillaries that delivers fluid to the tubules, called the glomerulus.
The Bowman‟s capsule and the glomerulus together constitute the renal corpuscle.
The endothelium of glomerulus has many pores (fenestrae).
The external layer of the Bowman's capsule is made up of simple squamous epithelium and the visceral
layer is made of epithelial cells called podocytes.
The podocytes end in foot processes are called filtration slits.
The renal tubule continues further to form the proximal convoluted tubule [PCT] followed by a
U-shaped loop of Henle (Henle‟s loop) that has a thin descending and a thick ascending limb.
The ascending limb continues as a highly coiled tubular region called the distal convoluted tubule [DCT].
The DCT of many nephrons open into a straight tube called collecting duct.
The collecting duct runs through the medullary pyramids in the region of the pelvis.
Several collecting ducts fuse to form papillary duct that delivers urine into the calyces, which opens into
the renal pelvis.
5. Haemodialysis :-
Malfunctiong of the kidneys can lead to accumalation of urea and other toxic substances, leading to kidney
failure.
In such patients toxic urea can be removed from the blood by a process called haemodialysis.
A dialyzing machine or an artificial kidney is connected to the patient‟s body.
A dialyzing machine consists of a long cellulose tube surrounded by the dialysing fluid in a water bath.
The patient‟s blood is drawn from a conveinent artery and pumped into the dialysing unit after adding an
anticoagulant like heparin.
The tiny pores in the dialysis tube allows small molecules such as glucose, salts and urea to enter into the
water bath, whereas blood cells and protein molecules do not enter these pores.
This stage is similar to the filtration process in the glomerulus.
The dialysing liquid in the water bath consists of solution of salt and sugar in correct proportion in order to
prevent loss of glucose and essential salts from the blood.
The cleared blood is then pumped back to the body through a vein.
6. Kidney Transplantation :-
It is the ultimate method for correction of a acute renal failures.
This involves transfer of healthy kidney from one person (donor) to another person with kidney failure.
The donated kidney may be taken from a healthy person who is declared brain dead or from sibling or
close relatives to minimise the chances of rejection by the immune system of the host.
Immunosuppressive drugs are usually administered to the patient to avoid tissue rejection.
7. Uremia :–
Uremia is characterized by increase in urea and other non-protein nitrogenous substances like uric acid
and creatinine in blood .
Normal urea level in human blood is about 17-30mg/100mL of blood.
The urea concentration rises as 10 times of normal levels during chronic renal failure.
8. Renal calculi :-
Renal calculi, also called renal stone or kidney stone or nephrolithiasis, is the formation of hard stone like
masses in the renal tubules of renal pelvis.
It is mainly due to the accumulation of soluble crystals of salts of sodium oxalates and certain phosphates.
This result in severe pain called “renal colic pain” and can cause scars in the kidneys.
Renal stones can be removed by techniques like pyleothotomy or lithotripsy.
9. Glomerulonephritis :-
It is also called Bright‟s disease and is characterized by inflammation of the glomeruli of both kidneys and
is usually due to post-streptococcal infection that occurs in children.
Symptoms are haematuria, proteinuria, salt and water retention, oligouria, hypertension and pulmonary
oedema.
32. What are the different types of rib bones that form the rib cage ? (March-2023)
1) True ribs’ / vertebro–sternal ribs – The first 7 pairs of ribs.
2) False ribs’ / vertebro-chondral ribs - The 8, 9 and 10th pairs of ribs do not articulate directly with the
sternum but joined with the cartilaginous (hyaline cartilage) part of the seventh rib.
3) Floating ribs’ / vertebral ribs - The last 11th and 12th pairs of ribs are not connected ventrally.
33. What are the bones that make the pelvic girdle?
The pelvic girdle is composed of two hip bones called Coxal bones that secure the lower limbs.
Each Coxal bone consists of three fused bones, ilium, ischium and pubis.
A deep hemispherical socket called the acetabulum is present on the lateral surface of the pelvis. It
receives the head of the femur.
Ventrally the two halves of the pelvic girdle meet and form the pubic symphysis containing fibrous
cartilage.
The ilium is the superior flaring portion of the hip bone. Each ilium forms a secure joint with the sacrum
posteriorly.
The ischium is a curved bar of bone. The V-shaped pubic bones articulate anteriorly at the pubic
symphysis.
ADDITIONAL QUESTION
1. Structure of a skeletal muscle fibre :- (fig :9.2 – page :30)
Each muscle fibre is thin and elongated. Most of them taper at one or both ends.
Muscle fibre has multiple oval nuclei just beneath its plasma membrane or sarcolemma.
The cytoplasm of the muscle fibre is called the sarcoplasm. It contains glycosomes, myoglobin and
sarcoplasmic reticulum.
Myoglobin is a red- coloured respiratory pigment of the muscle fibre. It is similar to haemoglobin and
contains iron group that has affinity towards oxygen and serves as the reservoir of oxygen.
Glycosomes are the granules of stored glycogen that provide glucose during the period of muscle activity.
Actin and Myosin are muscle proteins present in the muscle fibre.
Along the length of each myofibril there are a repeated series of dark and light bands.
The dark A-bands (Anisotropic bands) and the light I-bands (Isotropic bands) are perfectly aligned with
one another. This type of arrangement gives the cell a striated appearance.
Each dark band has a lighter region in its middle called the H-Zone. Each H-zone is bisected vertically by a
dark line called the M-line.
The light I-bands also have a darker mid line area called the Z–disc.
The myofibrils contain the contractile element, the sarcomere is the functional unit of the skeletal muscle.
A Sarcomere is the region of a myofibril between two successive Z-discs. It contains an A-band with a
half I-band at each end.
Inside the sarcomere two types of filaments are present namely the thick and thin filaments.
The thick filaments extend the entire length of the A-band, the thin filaments extend across the I-band and
partly into the A-band.
The invagination of the sarcolemma forms transverse tubules (T–tubules) and they penetrate into the
junction between the A and I-bands.
16. Sam‟s optometrist tells him that his intraocular pressure is high. What is this condition called and which
fluid does it involve?
Any block in the canal of schlemm increases the infra ocular pressure of aqueous humor and leads to
„Glaucoma’.
Where the optic nerve and the retina are compressed due to pressure.
17. The action potential occurs in response to a threshold stimulus; but not at sub threshold stimuli.What is the
name of the principle involved?
The principle involved - all or none principle.
The action potential occurs in response to a threshold stimulus but does not occur at subthreshold stimuli.
This is called all or none principle.
18. Pleasant smell of food urged Ravi to rush into the kitchen. Name the parts of the brain involved in the
identification of food and emotional responses to odour.
The hypothalamus contains a pair of small rounded body called mammillary bodies that are involved in
olfactory reflexes and emotional responses to odour.
19. Cornea transplant in humans is almost never rejected. State the reason.
The Cornea is a non-vascular transparent coat formed of stratified squamous epithelium.
They donot have blood vessels, So it can be transplanted from one person to another.
20. At the end of repolarization, the nerve membrane gets hyperpolarized. Why?
If repolarization becomes more negative than the resting potential -70 mV to about -90 mV, it is called
Hyperpolarization.
During this, K+ ion gates are more permeable to K+ even after reaching the threshold level as it closes
slowly; hence called Lazy gates.
22. What is the ANS controlling centre? Name the parts that are supplied by the ANS.
ANS controlling centre is in the hypothalamus.
The autonomic neural system is auto functioning and self governed.
It is a part of peripheral neural system that innervates smooth muscles, glands and cardiac muscle.
This system controls and coordinates the involuntary activities of various organs.
23. Why the limbic system is called the emotional brain? Name the parts of it.
The inner part of the cerebral hemisphere constitutes the limbic system.
The main components of limbic system are olfactory bulbs, cingulate gyrus, mammillary body,
amygdala, hippocampus and hypothalamus.
The limbic system is called „emotional brain‟ because it plays a primary role in the regulation of pleasure,
pain, anger, fear, sexual feeling and affection.
18. Write the causes for Diabetes mellitus and Diabetes insipidus.
Diabetes mellitus Diabetes insipidus
It is caused due to reduced secretion of insulin. It is caused due to hyposecretion of vasopression
As the result, blood glucose level is elevated. The (ADH) from neurohypophysis. The symptoms are
Symptoms are polyurea, polydipsia and polyphagia. polyurea and polydipsia.
22. Name the layers of Adrenal cortex and mention their secretions. :-
The outer region of the kidney is the cortex and the inner
region is the medulla.
Histologically the adrenal cortex has three distinct zones,
zona glomerulosa, zona fasciculata and zona reticularis.
1) Zona glomerulosa - an outer thin layer constitutes about
15% of adrenal cortex, and secretes mineralocorticoids.
2) Zona fasciculata - the middle layer constitutes about 75%
of adrenal cortex and secretes glucocorticoids such as
cortisol, corticosterone and trace amounts of adrenal
androgen and oestrogen.
3) Zona reticularis - an inner zone of adrenal cortex constitute about 10% of adrenal cortex and secretes the
adrenal androgen, trace amount of oestrogen and glucocorticoids.
25. Growth hormone is important for normal growth. Justify the statement :-
Growth hormone promotes growth of all the tissues and metabolic process of the body.
It influences the metabolism of carbohydrates, proteins and lipids.
It stimulates chondrogenesis (cartilage formation), osteogenesis (bone formation) and helps in the
retention of minerals like nitrogen, potassium, phosphorus, sodium etc., in the body.
GH increases the release of fatty acid from adipose tissue.
Thus it conserves glucose for glucose dependent tissues, such as the brain.
28. Predict the effects of Removal of Pancreas from the human body.
Pancreas is a composite gland which performs both exocrine and endocrine functions.
If removal of Pancreas from the human body can be dangerous and life-chaning.
Removing the pancreas can also indegestive process takesplaces, due to lack of amylase, lypase,
Carboxypeptidase, and nuclease enzymes.
People cannot produce enough insulin and develop Diabetes and sugar level not balance in the blood.
ADDITIONAL QUESTION
1) Differentiate Exocrine glands from Endocrine glands :-
Exocrine glands Endocrine glands
The exocrine glands secrete enzymes, saliva and The endocrine glands, called ductless glands produce
sweat and have ducts that carry their substances to hormones and lack ducts; they release their hormone
the membrane surfaces. to the surrounding tissue fluid. Example : Pituitary,
Example: salivary gland and gastric gland. thyroid, parathyroid, pineal, adrenal, thymus
3) Hypothalamus :-
It is a small cone shaped structure, that projects downward from the brain ending into the pituitary stalk.
It interlinks both the nervous system and endocrine system.
The master endocrine Pituitary gland is controlled by the hypothalamus.
Hypothalamus contains groups of neurosecretory cells. It produces neurotransmitters which regulate
the secretions of the pituitary.
It produced hormones, it act either as a releasing hormone or as an inhibitory hormone.
Hypothalamus maintains homeostasis, blood pressure, body temperature, cardio and fluid electrolyte
balance of the body. As the part of limbic system it influences various emotional responses.
5) Hormones of neurohypophysis
i) Vasopressin or Anti Diuretic Hormone (ADH) :
ADH is a peptide hormone which promotes reabsorption of water and electrolytes by distal tubules of
nephron and thereby reduces loss of water through urine.
Hence it is called as anti diuretic hormone. It also causes constriction of blood vessels when released in
large amount and increases blood pressure.
ADH deficiency causes Diabetes insipidus which induces the production of large amount of urine.
6) Thymus gland :-
Thymus gland is partially an endocrine and partially a lymphoid organ.
It is a bilobed structure located just above the heart and aorta, behind the sternum.
It is covered by fibrous capsule and it is divisible into an outer cortex and an inner medulla.
It secretes four hormones such as thymulin, thymosin, thymopoietin & thymic humoral factor (THF).
The primary function is the production of „T’ lymphocytes which provides cell mediated immunity.
9) Functions of testosterone:-
Under the influence of FSH and LH, testosterone initiates maturation of male reproductive organs.
The appearance of secondary sexual characters, muscular growth, growth of facial and axillary hair,
masculine voice and male sexual behaviour.
It enhances the total bone matrix and plays a stimulating role in the process of spermatogenesis.
10. Hypo and Hyper activity of endocrine glands and related disorders :-
N Diseases Secretion type Symptoms
Hypo secretion of In children - skeletal growth, sexual maturity is arrested, they attain a
1. Dwarfism
Growth hormone maximum height of 4 feet only.
Hyper secretion of In children – overgrowth of skeletal , upto 8 feet.
2. Gigantism
GH
Excessive secretion In Adult - Over growth of hand bones, feet bones, jaw bones,
3. Acromegaly
of GH malfunctioning of gonads, enlargement of viscera, endocrine gland.
Hypothroidism- In infants- retarded skeletal growth, absence of sexual maturity,
4. Cretinism hypo secrrtion of retarded mental ability, thick wrinkled skin, protruded enlarged tongue,
Thyroid bloated face, thick and short limbs occurs.
In adults- decreased mental activity, memory loss, slowness of
Myxodema /
Hypo secretion of movement, speech, and general weakness of body, dry coarse skin,
5. Gull‟ disease
Thyroid scarce hair, puffy appearance, disturbed sexual function, low BMR,
poor appetite, and subnormal body temperature.
Grave‟sdisease enlargement of thyroid gland, increased BMR (50% - 100%),
Thyrotoxicosis Hyper secretion elevated respiratory and excretory rates, increased heart beat, high BP,
6.
Exophthalmic of thyroid increased body temperature, protrusion of eyeball and weakness of eye
goitre muscles and weight loss.
Simple Hyposecretion Enlargement of thyroid gland, fall in serum thyroxine level, increased
6. 7.
goitre of thyroxine TSH secretion.
Tetany Hyposecretion of Serum calcium level decreases (Hypocalcemia), Generalized
7. 8. (March- Parathyoid convulsion, locking of jaws increased heart beat rate, increased body
2023) hormone (PTH) temperature, muscular spasm are the major symptoms.
Hyperpara- Hypersecretion of Demineralisation of bone, cyst formation, softening of bone, loss of
8. 9.
thyoidism PTH muscle tone, general weakness, renal disorders.
Hyposecretion of Muscular weakness, low BP., loss of appetite, vomiting, hyper
9. 10 Addison‟s glucocorticoids and pigmentation of skin, low metabolic rate, subnormal temperature,
. disease
mineralocorticoids reduced blood volume, weight loss are the symptoms.
Obesity of the face and trunk, redness of face, hand, feet, thin skin,
11 Cushing‟s Excess secretion of excessive hair growth, loss of minerals from bone (osteoporosis).
. syndrome cortisol systolic hypertension, and suppression of sexual function like atrophy
of gonads.
14) Animal husbandry is the science of rearing, feeding and caring, breeding and disease control of animals.
It ensures supply of proper nutrition to our growing population through activities like increased production
and improvement of animal products like milk, eggs, meat, honey, etc.
a. Poultry production depends upon the photoperiod.Discuss
The photoperiod is an important for growth and reproductive process in chicken.
The light increase the metabolism of chicken and laying more eggs.
b. Polyculture of fishes is of great importance.
1. All available niches are fully utilized.
2. Compatible species do not harm each other.
3. No competition among different species is found.