Tablets MCQs

Q74Which of the following is not true with reference to the popularity of
tablets?
A o being a unit dosage form, tablets offer accuracy of dose
B o the oral route is the most convenient and safe way of
administering drugs
C o tablets are easy to produce on a bulk scale
D o tablets are usually costlier compared with oral liquid
formulations
E o tablets offer better stability for most drugs compared with
liquid dosage forms
Q75 The process of tablet formation involves three stages. Which of the
following is the correct sequence?
A o die filling > compression > ejection
B o compression > die filling > ejection
C o die filling>ejection>compression
D o ejection>die filling>compression
E o compression>ejection>die filling
Q76 A number of powder properties need to be optimised and controlled
in the tabletting process. Which of the following options best
describes these properties?
1 o homogeneous mixing of powder with minimal segregation
2 o compression characteristics
3 o flow behaviour
4 o adhesion and friction
A o 1 and 2
B o 2 and 3
C o 3 and 4
D o 1, 2 and 3
E o 1, 2, 3 and 4
Q77 Which of the following is not the correct pair of equipment and unit
operation?
A o high shear mixer: mixing of powder

B o high shear mixer: agglomeration
C o fluidised-bed dryer: size reduction
D o hammer mill: size reduction
E o tablet press: tabletting
Q78 Which of the following is true regarding direct compression?
A o the process of direct compression is as complex as wet
granulation
B o direct compression is cheaper than wet granulation and
compression
C o there is no difference in stability between tablets produced
by any method
D o any material can be directly compressed with modern
tabletting equipment
E o direct compression cannot be used for potent drugs
Q79 Which of the following tablet excipients is not used as a filler?
A o lactose
B o calcium carbonate
C o dicalcium phosphate
D o sorbitol
E o polyvinyl pyrrolidone
Q80 Which of the following is the most commonly used lubricant in tablet
manufacturing?
A o polyethylene glycol
B o liquid paraffin
C o magnesium stearate
D o stearic acid
E o sodium lauryl sulfate
Q81 Which of the following can be used as a dry binder?
A o gelatin
B o sucrose
C o starch
D o polyvinyl pyrrolidone
E o sodium starch glycolate
Q82 Which of the following mechanisms can facilitate tablet disintegration?
1 o swelling of disintegrants by sorption of water, leading to
rupture of the tablet
2 o promotion of penetration of liquid inside the tablets, such
as that caused by surface active agents
3 o evolution of gas such as carbon dioxide, in the presence
of water
Ao1
Bo2
Co3
D o 1 and 2
E o 1, 2 and 3
Q83 Which of the following is incorrect with reference to lubrication during
tabletting?
A o glidants improve flowability during the tabletting process
B o colloidal silica is the most commonly used glidant
C o lubricants reduce the friction between tablet and die,
helping with compression and ejection
D o lubricants also help with tablet disintegration and dissolution
E o magnesium stearate is an example of a commonly used
lubricant
Q84 Which of the following types of tablet can be used for the sustained
release of drugs?
A o disintegrating
B o chewable
C o effervescent
D o buccal
E o sublingual
Q85 Which of the following is not true with reference to lozenges?
A o compressed lozenges are designed to dissolve slowly and
release the drug in the saliva

B o lozenges are often coloured and flavoured
C o similar to other tablets, lozenges contain gelatin as the
disintegrating agent
D o glucose and sorbitol are commonly used as fillers in
lozenges
E o lozenges are generally produced by compression at high
pressure
Questions 86 and 87 involve the following case:
A formulation scientist is asked to develop a cost-effective vaginal
dosage form for tropical countries. The drug is highly water-soluble
at pH 4.0 and is designed for local vaginal infection. The immediate
release of defined amount of drug and prolonged retention in the
vagina is desirable for optimal biological effect.
Q86 Which of the following is the best formulation option?
A o cocoa butter suppository
B o vaginal tablet
C o vaginal capsule
D o foam
E o solution for vaginal application
Q87 If a solid dosage form is selected as an option, which of the following
properties should be included in the design?
A o rapid disintegration
B o stability at temperatures above body temperature
C o bioadhesion
D o non-irritant formulation
E o all of the above
Q88 Which of the following can be used as a binder in aqueous and nonaqueous
systems?
A o polymethacrylates
B o acacia
C o starch
D o sucrose
E o alginic acid
Q89 Which of the following is (are) used as drug-elease mechanisms in
prolonged-release tablets?
1 o diffusion control
2 o dissolution control
3 o erosion control
Ao1
Bo2
Co3
D o 1, 2 and 3
E o 1 and 2
Q90 Which of the following is not the correct pair of test parameter and
method used for assessment?
A o uniformity of content: assay of active ingredient
B o mechanical strength: hardness test
C o release profile: disintegration test
D o microbial load: sterility testing
E o mottling: surface appearance
Q91 Which of the following best describes the reasons for carrying out
dissolution studies?
1 o to estimate the likely in vivo behaviour, based on in vitro data
2 o to act as a quality-control tool
3 o to develop generic formulations for specific brands
Ao1
Bo2
Co3
D o 1, 2 and 3
E o 1 and 3

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Q74Which of the following is not true with reference to the popularity of

A o being a unit dosage form, tablets offer accuracy of dose

B o the oral route is the most convenient and safe way of

C o tablets are easy to produce on a bulk scale

D o tablets are usually costlier compared with oral liquid

E o tablets offer better stability for most drugs compared with

liquid dosage forms

following is the correct sequence?

A o die filling > compression > ejection

B o compression > die filling > ejection

Q76 A number of powder properties need to be optimised and controlled

in the tabletting process. Which of the following options best

describes these properties?

1 o homogeneous mixing of powder with minimal segregation

4 o adhesion and friction

A o high shear mixer: mixing of powder

C o fluidised-bed dryer: size reduction

D o hammer mill: size reduction

E o tablet press: tabletting

Q78 Which of the following is true regarding direct compression?

A o the process of direct compression is as complex as wet

B o direct compression is cheaper than wet granulation and

C o there is no difference in stability between tablets produced

D o any material can be directly compressed with modern

E o direct compression cannot be used for potent drugs

Q79 Which of the following tablet excipients is not used as a filler?

E o sodium lauryl sulfate

Q81 Which of the following can be used as a dry binder?

Q82 Which of the following mechanisms can facilitate tablet disintegration?

1 o swelling of disintegrants by sorption of water, leading to

rupture of the tablet

2 o promotion of penetration of liquid inside the tablets, such

as that caused by surface active agents

3 o evolution of gas such as carbon dioxide, in the presence

Q83 Which of the following is incorrect with reference to lubrication during

A o glidants improve flowability during the tabletting process

B o colloidal silica is the most commonly used glidant

C o lubricants reduce the friction between tablet and die,

helping with compression and ejection

D o lubricants also help with tablet disintegration and dissolution

E o magnesium stearate is an example of a commonly used

Q85 Which of the following is not true with reference to lozenges?

A o compressed lozenges are designed to dissolve slowly and

release the drug in the saliva

C o similar to other tablets, lozenges contain gelatin as the

D o glucose and sorbitol are commonly used as fillers in

E o lozenges are generally produced by compression at high

Questions 86 and 87 involve the following case:

A formulation scientist is asked to develop a cost-effective vaginal

dosage form for tropical countries. The drug is highly water-soluble

at pH 4.0 and is designed for local vaginal infection. The immediate

release of defined amount of drug and prolonged retention in the

vagina is desirable for optimal biological effect.

Q86 Which of the following is the best formulation option?

A o cocoa butter suppository

E o solution for vaginal application

Q87 If a solid dosage form is selected as an option, which of the following

properties should be included in the design?

B o stability at temperatures above body temperature

E o all of the above