Thoracic 53
Thoracic 53
Thoracic 53
Anaesthesia
& Intensive Care
Part 8: Thoracic Anaesthesia
:
The indications for placement of a Double Lumen Tube in Anaesthesia and Critical Care:
1. To facilitate surgery
a. Lung surgery, e.g. pneumonectomy, lobectomy
b. Non-lung surgery, e.g. pericardial window, diaphragmatic hernia repair, oesophagectomy
Pre-operative respiratory assessment you would use in an adult to decide whether a patient
could tolerate lung resection:
1. Spirometry
a. FEV1>1.5L for lobectomy, FEV1 >2.0L for pneumonectomy
b. FEV1 >80% normal predicted for pneumonectomy
- Spirometry (post bronchodilator) and exercise data are used to predict the perioperative risk and
postoperative respiratory reserve i.e. pulmonary function and risk of respiratory failure.
- The predicted post-operative FEV1 (ppoFEV1) can be estimated from the formula using the total
number of segments in both lungs, 19 (9 in left, 10 in right) and the number of segments to be
resected(y).
Complications following thoracic surgery may be classified into early or late complications:
Early (usually within the first 72 hours):
*Respiratory insufficiency
*Mediastinal or subcutaneous emphysema
*Mediastinal shift
*Vocal cord injury
*Haemorrhage
*Arrhythmias
Later complications:
*Pneumonia
*ALI
*Bronchopleural fistula
* DVT
*PE
- This
classification does not include aneurysms that involve only the descending aorta.
-Classification is important as it allows risk stratification based on the extent of aorta involved.
-It also gives an idea of what will be encountered in surgery and is important for reporting of results
as more extensive aneurysms are associated with greater mortality and morbidity.
-Type 2 TAA’s carry more risk and complications.
* Crosses
clamping occurs above and below the lesion to allowing the aneurysm to be opened and
replacement with a graft to occur.
* Clamping produces:
- Proximal hypertension; depends on clamp location, degree of collaterals & preocclusion aortic flow.
- Distal hypo-perfusion
- Increase in cardiac filling pressure, myocardial wall stress and VO2
- Decrease in CO and EF
- Reflex bradycardia, contractility and peripheral vasodilation in response to hypertension.
* Distal
to the clamp there is:
- Decrease oxygen consumption
- Conversion to anaerobic metabolism
- The risk and extent of complications is related to the duration of cross clamping.
- Risk of renal failure increases with longer cross clamp times. Mannitol has been shown to improve
postoperative renal function.
- Risk of ischaemic neurological injury also increases with prolonged cross clamping. It usually
presents with paraplegia but other neurological complications can occur.
The degree of collateral blood supply, renal dysfunction and hyperglycaemia the risk of injury.
- Blood loss
- Depletion of coagulation factors
- DIC
- Hypothermia
- Hypocalcaemia after hepatic hypoperfusion
- Respiratory insufficiency.
Contents:
Spinal nerves, Sympathetic chain, Intercostal
vessels, fat and Rami communicantes.
The Technique of Paravertebral Blockade:
- Consent, equipment preparation, monitoring,
assistance, asepsis.
- Position: sitting if awake, lateral if asleep
(operative site up), head and neck flexed.
- Mark skin at spinous processes of level required, and corresponding transverse processes 2.5cm
laterally. Local to skin if awake.
- 18G Tuohy inserted at TP perpendicular to skin until bony contact obtained, depth 3.5-4.5cm.
- Needletip ‘walked off’ TP caudally until 1cm deeper than bony contact and local anaesthetic
injected after aspiration.
- 15ml blocks roughly 3 dermatomes (sympathetic block 8 dermatomes).
- Loss of resistance may assist in finding this point but is not a complete loss.
- Peripheral nerve stimulator will elicit intercostal muscle contraction.
*If ultrasound guidance is used:
- linear probe 5cm from midline craniocaudally and moved medially to identify rib/TP join and needle
inserted ‘out-of-plane’.
- A catheter may be inserted after 10ml LA to expand the space; advance catheter 2cm into space.
Surgical placement of paravertebral catheters also possible and reliable.
- Surgical Anesthesia
(Unilateral):
Sympathetic block:
*Relief of hyperhidrosis / SVT
Absolute:
-Patient refusal
-Allergy to agents
-Empyema.
-Local sepsis
-Tumour spread to space
Relative:
-Coagulopathy
-Severe respiratory disease where intercostal muscle block inadvisable.
-Distorted anatomy such as Spinal Scoliosis.
Airway
- Surgical access to pleural cavity is required. Various techniques have been described-
* Use of double lumen endotracheal tube- one lung isolated and then the other for bilateral
surgery- this gives very good surgical conditions with collapsed lung
* Single lumen ETT with bronchial blocker
* Single lumen ETT with two lung ventilation- CO2 in pleural cavity- high pressures generated
within pleural cavity can cause haemodynamic compromise and operating conditions not as good
as with one lung ventilation
Post-operative Complications:
- Pneumothorax- may or may not require drainage
- Horner’s syndrome
- Compensatory sweating
- Gustatory sweating
- Pleural effusions
- Haemothorax
Absolute indications
- Isolation of one lung from the other to avoid spoilage in unilateral infection or massive he.
- Control of distribution of ventilation-
- Giant unilateral lung cyst or bulla
- Bronchopleural fistula, bronchopleural cutaneous fistula
- Open surgery on main bronchus
- Life threatening hypoxia due unilateral lung disease
- Tracheobronchial tree disruption
- Bronchoalveolar lavage- risk contamination to other lung
Relative
- Surgical access- pneumonectomy, lobectomy, oesophagectomy, VATS, mediastinal exposure, Spinal
surgery, Thoracic aneurysm repair
- Post cardiac bypass after removal of totally concluding chronic unilateral PE.
- Blood flow to the non-dependent lung does’t take part in gas exchange & this shunt causes hypoxia.
- The (lower) dependent lung; has increased perfusion compared non-dependant lung due gravity
and surgical compression and lung retraction on the non-dependent lung therefore receives a
greater percentage of CO this therefore decreases shunt.
If pneumonectomy and vessels are ligated entirely then this will decrease shunt further.
- Hypoxic pulmonary vasoconstriction (HPV) diverts blood flow from the non-ventilated to the
ventilated lung, thereby reducing venous admixture and ameliorating the decrease in PaO2.
It involves the constriction of small arterioles (and to a lesser degree, venules and capillaries) in
response to alveolar hypoxia.
- Expansion of the dependent lung is restricted by the weight of the mediastinum, the cephalad
displacement of the diaphragm and abdominal organs, and non compliance of the hemi-thoracic
chest wall.
- The alveolar compliance curve is shifted down and to the left in the dependent lung. This leads to
atelectasis of the dependent lung, decreasing the ventilated lung surface. This causes HPV, increased
resistance to flow in the dependent pulmonary artery, and diversion of flow to the non-dependent
Management of Hypoxemia:
- Recognise hypoxaemia
- ABC approach anf Place FiO2 1.0
- Check tube disconnection / ventilator working
- Check ventilator settings
- Check DLT movement with fibre-optic scope
- Check secretions/ debris - suction
- Maintain PaCO2 5.3kpa as lower can decrease HPV
- Place O2 flow into dependant lung
- Place CPAP to dependant lung - tell surgeon
- Add peep 5 cmH2O to non-dependant lung
- Tell surgeon need to reinflate lung
- Clamp pulmonary artery
- Extends downwards from cricoid cartilage at level of C6 vertebra in the midline to the level of T5-6.
- 10-11cm in length and 20mm in diameter.
- The trachea bifurcates into the right and left main bronchi.
It is positioned more vertically than the left main. The Rt. main bronchus is shorter and wider than
the left main bronchus, 3cm VS 5cm. At 2.5cm along the right main bronchus arises the right
upper lobe bronchus. At 3 cm the Rt. main bronchus bifurcates into the right middle and lower
lobe bronchi.
-Left and right DLTs cannulate the trachea and the appropriate main bronchus.
-Right sided bronchial limbs have side hole to ventilate right upper lobe.
-Large external diameter, small internal diameter (39 F” DLT has ED of 13mm & ID of 6mm).
-Usually Lt. sided tubes selected except when surgery involves Lt. main bronchus, due to difficulty in
ventilation of Rt. upper lobe bronchus.
-Tube has 2 lumens allowing lung isolation and collapse of either lung. This is achieved by clamping
the desired lumen and opening to the atmosphere.
-Various types of DLT: Robsertshaw, Bronchocath, Sheribronch, Carlens (Rt. sided), Whites (Lt. sided)
Sizing of DLT:
- The DLT is inserted via normal laryngoscopy passing the bronchial portion through the cords with
the tip pointing anteriorly.
-Rotate the tube through 90° to intended side of cannulation. Advance tube as far as it will go
without undue force.
-Average depth of 29cm in adults has been estimated.
- Inflate tracheal cuff to achieve a seal.
- The tracheal side of the adapter is then clamped and the tracheal port is opened distal to the
clamp.
-The bronchial cuff is inflated; so as to just eliminate air leak from the tracheal lumen - 1ml at a time
until leak stops. If a reasonable seal cannot be achieved with less than 4ml of air the tube is either
too small or incorrectly placed.
- Auscultate the chest - breath sounds should be heard only on the side of endobronchial intubation.
-Look for unilateral chest expansion. Assess compliance via manual ventilation. Also note a change in
- Fibreoptic Bronchoscopy; down the tracheal lumen should reveal the carina. The top edge of the
blue bronchial cuff should be just visible in the intended main stem bronchus. When a right-sided
tube is used, the fibrescope should be used to visualise the orifice of the right upper lobe bronchus.
- Repeat checks after positioning in the lateral decubitus position.
- Chest X-ray:
-AP/lateral/olique/decubitus
- fluid will gather in most dependent part of chest. Meniscus formed.
-On erect AP 75ml of fluid is needed to obscure the costophrenic angle, 500ml to obscure the
diaphragm, 1000ml to reach 4th anterior rib.
-On decubitus films may see apical capping which disappears on erect film
- CT scan:
-Split pleura sign (enhancement of visceral and parietal pleura after injection of iv contrast).
-Can distinguish an empyema from an abscess
- Ultra-sound scan:
-Identifies free or loculated pleural effusions.
-Can be used for chest drain insertion and thoracocentesis.
- Therapeutic
* Aid tracheostomy procedure and difficult intubation/difficult airway
* Retrieval of foreign body from airway
* LASER tissue removal/basket/forceps
* Endobronchial toilet in VAP
* Aid in placement of DLT and bronchial blocker in selective intubation of bronchus
* Airway balloon dilatation in tracheobronchial stenosis
- Relative
*Coagulopathy
*Refractory hypoxaemia
*Unstable haemodynamics/Dysarrythmias/recent MI/CCF
*Pulmonary hypertension
https://www.youtube.com/watch?v=VLsXe5oB2W0
http://www.thoracic-anesthesia.com/?page_id=2
https://www.youtube.com/watch?v=ThYHLG50pH0
https://bronchoscopy.org/
https://www.youtube.com/watch?v=phRv73Ik7fI&lr=1
Systemic
-Cachexia and malnutrition
-Eaton-Lambert syndrome: an autoimmune disease a/w malignancy that affects the pre-synaptic
release of ACh and renders patients very sensitive to neuromuscular block
-Endocrine abnormalities such as hyperparathyroidism, SIADH, Cushing’s syndrome
-Previous chemotherapy can lead to venous thrombosis and produce cardiac side-effects
-Immunosuppression
Local
-SVC obstruction
-Airway obstruction
-Damage of vocal cord’s innervation (e.g. stretching of the recurrent laryngeal nerve on the left)
-Previous radiotherapy can cause fibrosis of the soft tissues around the upper airway causing
difficulty with laryngoscopy
Benign
-Tracheo/bronchomalacia
-Goitre
-Webs
-Granulation tissue (ETT, foreign body, Wegener’s granulomatosis
post-transplant)
-Lymphadenopathy (infectious, sarcoid)
-Tracheal- or bronchial- oesophageal fistula
Malignant
-Primary endoluminal carcinoma
-Metastatic carcinoma
-Oesophageal carcinoma
-Mediastinal tumours (thymus,
thyroid, teratoma)
-Lymphadenopathy (malignancy)
-Lymphoma
An emergency surgical airway will not resolve a crisis of ventilation if the stenosis cannot be
passed intraluminally
Intra- operative
-Full pre-oxygenation
-Confirm surgeon is in theatre before inducing patient
-Teamwork between anaesthetist, surgeon and theatre staff is important as airway is shared
Post- operative
-After manipulation, the airway may bleed or become oedematous
-The patient should be fully awake with normal neuromuscular function & be given supplemental O2
-A useful endpoint to signal suitability for discharge to a recovery unit is the presence of all parts of
the cough reflex
-Post-op pain is minimal AND long acting opiates are unhelpful when a fast & full recovery is needed
-Close monitoring is important
-Post-op respiratory compromise 2ry to oedema can respond to nebulised adrenaline & iv steroids
-Heliox should be available as it can improve gas flow in situations of critical airflow limitation due to
its low density making laminar flow more likely
- Some patients may warrant further investigations depending on the surgery they are undergoing
and underlying co morbidities, e.g. cardiac catheterisation
- Some of these investigations are paramount in deciding if a patient is fit to undergo major surgery,
such as exercise stress testing
- Investigations are useful in optimising patients for surgery, e.g. treating anaemia, optimising lung
function and treating undiagnosed comorbidities e.g. thyroid disease
- Symptoms/functional status may deteriorate if recipient has been waiting for a long time for
surgery and these need to be revaluated
- Donors need to investigated also, needing to meet the following criteria: PaO2 > 30Kpa on an FiO2
1.0, minimal infiltrates on CXR, negative culture of sputum.
- IV access. Large bore peripheral cannula, e.g. 14G x2. Arterial line, consider pre induction given
likelihood of significant comorbidities. Central venous access. Either before or after induction
depending on patient condition. Site; Internal Jugular vs Subclavian: Internal Jugular may be most
appropriate in midline sternotomy. Consider insertion of PA catheter.
- Fasting state and induction. Often a RSI or modified RSI technique should be considered as surgery
often occurring on a “full stomach” due to unanticipated nature of surgery
- Airway devices: Double lumen tube and fiberoptic scope to confirm placement
- Use of Cardiopulmonary bypass should be considered…even if not planned for may be required if
hypoxia is unmanageable when one lung ventilation is instituted and should be readily available
- Haemodynamics: May be compromised with induction agents, reduced CO with a high PEEP
(decreased venous return). Inotropes such as Dobutamine and vasopressors e.g. Noradrenaline
should be readily available. Measures for patients with pulmonary hypertension should be available
such as nebulised Prostacyclin.
- Monitoring: Standard AAGBI monitoring as for all anaesthetics. Arterial blood pressure monitoring
and CVP monitoring as discussed above. Consider CO monitoring devices such as TOE, or PA catheter
as mentioned above
- Analgesia: Commonly a thoracic epidural is sited preoperatively and used intra and post
operatively
- Drugs: Consider use of early premedication due to high levels of anxiety. Choice of induction agent
and dose dependent on anaesthetist and patient specifics, e.g. Opioid induction for cardiac stability if
history of significant IHD. No specific muscle relaxant of particular benefit, but a long acting agent
such as Pancuronium may suit nature of surgery
- Early use of Immuno-suppressants, either pre operatively or after induction. Agents such as
Steroids, Cyclosporin A and Azathioprine commonly used agents.
- Awareness of early post operative complications that can arise and early management of these. E.g.
respiratory failure requiring ongoing ventilation/reintubation. Early rejection, due to tissue mistyping
- Sterility and antimicrobial therapy. Consider Prophylactic Antiobiotic therapy, in conjunction with
surgical team and those used specifically in that unit. Sterility and prophylaxis of particular
importance in this patient group as they are often commenced on immunosuppressants at an early
juncture for protection of the newly implanted organ.
- General measures such as pressure point prophylaxis, temperature control, eye protection ….etc.
*Nasopalatine and post-nasal branches of Maxillary nerve of V2; branches of the trigeminal nerve.
ii) The
NB; the British Thoracic Society recommends an upper dose limit of 8.2 mg/kg for fibre-optic
bronchoscopy with topical lignocaine
- Nerve blocks:
-Glossopharynegeal
-Superior Laryngeal
-Recurrent Laryngeal nerve blocks
- General anaesthesia:
-Volatile agents or TIVA.
Indications
-Known difficult mask ventilation and/or difficult intubation
-Expected difficult mask ventilation e.g. head and neck tumours
-Patient at risk of aspiration with a difficult airway
-Neurological assessment required following intubation, e.g. cervical spine injury
-Morbid obesity
Contraindications (relative and absolute)
-Local anaesthetic allergy
-Patient refusal/uncooperative patient
-Lack of experience of anaesthetist
-When rapid airway control is required
-Critical airway; the flexible endoscope may obstruct the narrow airspace
-Blood in the airway - this may obscure vision making FOI impossible
-Prion disease
-Difficult anatomy; it may be impossible to access the glottis
-Airway obstruction at the level of the glottis may be exacerbated by both endoscopy and topical .
anaesthesia and therefore FOI should be used with caution
Infraclavicular approach is more desirable approach: There is less chance of accidental puncture
of pleura.
-It just like a straw in a drink, air can push through the straw, but air can not be drawn back up the
straw.
-When the rigid straw is above the liquid level in the bottle, the system would not be operated
consistently developing pneumothorax.
-However, when a significant quantity of liquid would be drained from the pleural cavity of the client,
the liquid level would be rose, thus requiring a greater pressure on the rigid straw to remove
effectively additional air from the pleural cavity to the bottle.
Features
Air/fluid leaves pleural cavity through tubing into drain and into water
o Air cannot flow back into pleural cavity as water impedes it
o Fluid cannot flow back into pleural cavity as long as the drain is kept adequately lower
than insertion site to prevent siphoning
May have multiple chambers
Indications
ICC
o Pneumothorax
o Large pleural effusion or empyema
Contraindications
Airomedical retrieval
o Cannot assure chamber will be below level of chest and fluid/air may siphon back into
pleural cavity
Procedure
Connect ICC to conector of UWSD
o Tape connections
Drain should be secured >80cm lower than insertion site of intercostal catheter
+/- apply suction
o Wall suction if 3 chambered
o Suction with low suction regulator if 1 or 2 chambers
Document and monitor
Complications
Tension pneumothorax
o If vent or tubing is blocked
No bubbling on respiration
o Pneumothorax resolved: CXR
o Inadequate pressure to expel remaining air: get patient to cough to check for bubbles
o ICC not in pleural cavity or clamped: so check location, remove clamp
o Vent from chamber blocked: unblock
No swinging
o Displaced ICC
o Disconnected ICC
o Blocked ICC
Re-expansion Pulmonary Oedema