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The Wiggers diagram, is a pectoral representation of the cardiac cycle (pressure, volume, sounds and

valve state in a heartbeat). The axes represent time, from zero ms to 800 ms (0.8s). The top Y axis
represents pressure from zero to 120 mm Hg. The bottom Y axis represents Left Ventricular volume.
There is an ECG, heart sounds and 6 heart states.

The pressure graph starts with the atrial contraction (Phase 1), when it contracts the pressure
increases to about 25 mm hg and then decreases. It decreased because the blood moved from left
atria to the left ventricle, and the force of the movement helps the mitral valve to close. The atrial
pressure increases again, because in isovolumetric contraction (phase 2) the blood pushes to the
aorta and to the atria as well, which makes the mitral valve to push back to the atria. Once the blood
has been ejected from the ventricles, the atrial pressure goes back and the pressure stays relatively
the same till the isovolumetric relaxation phase (phase 5), where the left atrium is being filled again,
and it fills till the pressure in left atrium overtakes the pressure in the left ventricle, this is where the
mitral valves is pushed open for the blood to dumped to the left ventricle. Because the blood is
going through to the ventricle, the pressure decreases again.

During atrial contraction, the pressure in the left ventricle will increase a bit because blood rushing
from the left atrium to the ventricle will hit the walls of the ventricle raising its pressure. In
isovolumetric contraction the left ventricle contracts, raising the pressure in that chamber, until a
point ~80 mm hg where the pressure in the ventricle allows the blood to push against the aortic
valve, which is depicted in the rise of the aorta pressure, in here the ventricular pressure overtakes
the aortic pressure which will open the aortic valve. The left ventricular and aorta pressure increases
to the maximum pressure generated. When the pressure is falling to ~100 mmHg the pressure in the
aorta is much higher than in the ventricle, making the aortic valve to shut. As the ventricle relaxes
the pressure decreases and would stay low until the next ventricular contraction. As for the aortic
pressure, when the aortic pressure closes, the pressure then tapers off until the next point when the
aortic valve opens again.

When the atria contracts into the left ventricles the blood volume will increase to above 125 mL
from 120 mL resting volume, however this is too much for the ventricles to handle thus some of the
blood goes up to the atrium again. Once the ventricle gets to the rapid ejection phase a lot of the
blood is traveling out of the ventricles causing this drop in left ventricular volume. Once the blood is
pumped out, the ventricles go into isometric relaxation phase and then into the rapid ventricular
filling phase where the blood volume increases again to the next cardiac cycle.

In the ECG (electric activity measure of heart). The first wave is the P wave which signifies the atrial
contraction. The QRS complex signifies the ventricular contraction. The T wave depicts ventricular
relaxation. After the T wave the ECG remains low until the next cardiac cycle in which the waves are
present again.

The heart sounds “Lub dup”. the major ones are during isometric contraction and isometric
relaxation. The heart sound is made due to the valves closing. The first heart sound (Lub) is
produced by the closure of the valve leaflets of the mitral valve. The second heart sound (dub) is
produced by the closures of the aortic valve leaflets. The heart sounds occur in parallel to the states
in which the pressure of ventricles overacts the pressure in aorta or atrium.

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