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Dengue Reviewer

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Dengue

Dengue is a viral infection transmitted to humans through the bite of infected mosquitoes. The primary
vectors that transmit the disease are Aedes aegypti mosquitoes and, to a lesser extent, Ae. Albopictus.
The virus responsible for causing dengue, is called dengue virus (DENV).

Patients who are already infected with the dengue virus can transmit the infection
via Aedes mosquitoes after the first symptoms appear (during 4-5 days; maximum 12). As a
precautionary approach, patients can adopt measures to reduce transmission by sleeping under
a treated net especially during the period of illness with fever.

Disease Process of Dengue

Transmission of Dengue Virus Pathophysiology

Types of Dengue

There are four dengue virus (DENV) types (DENV-1, DENV-2, DENV-3, and DENV-4), all of which are
capable of inducing severe disease (dengue hemorrhagic fever [DHF]/dengue shock syndrome [DSS]).

Different types of Dengue fever and it Signs and Symptoms

1. Dengue fever

2. Dengue hemorraghic fever (DHF) and

3. Dengue shock syndrome(DSS)


What is Dengue Fever

Dengue fever is a viral infection caused by the dengue virus that is transmitted through the bite of the
infected Aedes mosquito.

Symptoms of dengue fever include the below:

• sudden onset of fever that lasts 3 to 7 seven days

• a severe headache especially in the back of the eye

• pain experienced in the muscles and joints, especially in knees, ankles, elbows

You may also suffer from an unpleasant taste in the mouth, loss of appetite which is often accompanied
by abdominal pain, vomiting and diarrhea.

Other indications may be

• rashes on the arms and the legs,

• severe itchiness leading to peeling of skin and hair loss as well,

• heavy menstrual periods in women, minor bleeding from the nose or the gums

• flushing of the skin on the face and the neck

• fatigue and extreme tiredness

• any second instances of rash as the fever subsides

Adults and grown up children show these symptoms while young children may quite often not show any
symptoms at all.

Dengue hemorrhagic fever

What is dengue hemorrhagic fever?

Dengue hemorrhagic fever is also called as severe dengue. The mosquito borne viral infection dengue
ocassionally develops into potential lethal complication called dengue hemorrhagic fever. Dengue
Haemorrhagic Fever was first recognized in the 1950s during dengue epidemics in the Philippines and
Thailand. Today, severe dengue affects most Asian and Latin American countries and has become a
leading cause of hospitalization and death among children and adults in these regions. It has similar
features to dengue fever but it may be severe as compared to the former. It usually occurs if a person
has had dengue more than once but most of the patients recover quickly if they follow appropriate
medical treatment.

Symptoms of dengue hemorrhagic fever:

After the fever, for about two to five days, the symptoms below start appearing, but they start
decreasing when the fever starts to resolve

• severe abdominal pain

• persistent vomiting
• rapid breathing

• bleeding gums

• restlessness and blood in vomit

• fatigue

It can lead to potentially deadly complication due to plasma leaking, fluid accumulation, respiratory
distress, severe bleeding, or organ impairment if not treated in time.

Dengue Shock Syndrome

What is dengue shock syndrome?

Shock syndrome is a dangerous complication of dengue infection and is associated with high mortality.
He onset of shock in dengue can be dramatic, and its progression relentless. If you are aware of the signs
and symptoms of dengue shock syndrome which sets in after dengue hemorrhagic fever, the patient can
survive by undergoing proper medical treatment.

Symptoms of dengue shock syndrome:

• Fever, or history of acute fever, lasting 2–7 days, occasionally occurs in 2 phases

• Hemorrhagic tendencies, evidenced by at least one of the following

• A positive tourniquet test

• discoloration of skin or formation of purple spots due to internal bleeding

• Bleeding from the intestinal membrane, gastrointestinal tract, injection sites, or other locations

• Blood in feaces or vomit

• Deficiency of platelets in blood (100000/mm3 or less)

• Evidence of plasma leakage

All four of the above plus evidence of circulatory failure, manifested by

• Rapid weak pulse, and

• Narrow pulse pressure (<20mmHg) OR

• Abnormally low blood pressure for age, and

• Cold, clammy skin, and restlessness

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