SAFETY DATA SHEET

Creation Date 27-Jan-2010 Revision Date 17-Jan-2018 Revision Number 6

1. Identification
Product Name Methylene chloride

Cat No. : D37-1; D37-4; D37-20; D37-200; D37-200LC; D37-500; D37FB-19;

D37FB-50; D37FB-115; D37FB-200; D37POP-19; D37POPB-50;
D37POPB-200; D37RB-19; D37RB-50; D37RB-115; D37RB-200;
D37RS-19; D37RS-28; D37RS-50; D37RS-115; D37RS-200; D37SK-4;
D37SK-4LC; D37SS-28; D37SS-50; D37SS-115; D37SS-200;
D37SS-1350; D37RS1000ASME; NC1485726; D37RE200ASME;
NC1568702; NC1641358; XXMECLDOW2000; XXMECLDOW200LI
CAS-No 75-09-2
Synonyms Dichloromethane; DCM

Recommended Use Laboratory chemicals.

Uses advised against Food, drug, pesticide or biocidal product use

Details of the supplier of the safety data sheet

Company
Fisher Scientific
One Reagent Lane
Fair Lawn, NJ 07410
Tel: (201) 796-7100

Emergency Telephone Number

CHEMTRECÒ, Inside the USA:
800-424-9300
CHEMTRECÒ, Outside the USA:
001-703-527-3887

2. Hazard(s) identification
Classification
This chemical is considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200)

Skin Corrosion/irritation Category 2

Serious Eye Damage/Eye Irritation Category 2
Carcinogenicity Category 1B
Specific target organ toxicity (single exposure) Category 3
Target Organs - Central nervous system (CNS).
Specific target organ toxicity - (repeated exposure) Category 2
Target Organs - Liver, Kidney, Blood.

Label Elements

______________________________________________________________________________________________

Page 1 / 8
Methylene chloride Revision Date 17-Jan-2018
______________________________________________________________________________________________

Signal Word
Danger

Hazard Statements
Causes skin irritation
Causes serious eye irritation
May cause drowsiness or dizziness
May cause cancer
May cause damage to organs through prolonged or repeated exposure

Precautionary Statements
Prevention
Obtain special instructions before use
Do not handle until all safety precautions have been read and understood
Use personal protective equipment as required
Wash face, hands and any exposed skin thoroughly after handling
Wear eye/face protection
Do not breathe dust/fume/gas/mist/vapors/spray
Use only outdoors or in a well-ventilated area
Response
IF exposed or concerned: Get medical attention/advice
Inhalation
IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
Skin
IF ON SKIN: Wash with plenty of soap and water
If skin irritation occurs: Get medical advice/attention
Take off contaminated clothing and wash before reuse
Eyes
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
If eye irritation persists: Get medical advice/attention
Storage
Store locked up
Store in a well-ventilated place. Keep container tightly closed
Disposal
Dispose of contents/container to an approved waste disposal plant
Hazards not otherwise classified (HNOC)

WARNING. Cancer - https://www.p65warnings.ca.gov/.

3. Composition/Information on Ingredients
Component CAS-No Weight %
Methylene chloride 75-09-2 >99.5

4. First-aid measures
General Advice If symptoms persist, call a physician.

Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get

______________________________________________________________________________________________

Page 2 / 8
Methylene chloride Revision Date 17-Jan-2018
______________________________________________________________________________________________

medical attention.

Skin Contact Wash off immediately with plenty of water for at least 15 minutes. If skin irritation persists,
call a physician.

Inhalation Move to fresh air. If not breathing, give artificial respiration. Get medical attention if
symptoms occur.

Ingestion Clean mouth with water and drink afterwards plenty of water.

Most important symptoms and None reasonably foreseeable. Inhalation of high vapor concentrations may cause
effects symptoms like headache, dizziness, tiredness, nausea and vomiting
Notes to Physician Treat symptomatically

5. Fire-fighting measures
Suitable Extinguishing Media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Unsuitable Extinguishing Media No information available

Flash Point No information available

Method - No information available

Autoignition Temperature 556 °C / 1032.8 °F

Explosion Limits
Upper 23 vol %
Lower 13 vol %
Sensitivity to Mechanical Impact No information available
Sensitivity to Static Discharge No information available

Specific Hazards Arising from the Chemical

Thermal decomposition can lead to release of irritating gases and vapors. Keep product and empty container away from heat and
sources of ignition.

Hazardous Combustion Products

Carbon monoxide (CO) Carbon dioxide (CO2) Hydrogen chloride gas Phosgene
Protective Equipment and Precautions for Firefighters
As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full
protective gear.

NFPA
Health Flammability Instability Physical hazards
2 1 0 N/A

6. Accidental release measures

Personal Precautions Use personal protective equipment. Ensure adequate ventilation.
Environmental Precautions Should not be released into the environment.

Methods for Containment and Clean Soak up with inert absorbent material. Keep in suitable, closed containers for disposal.
Up

7. Handling and storage

Handling Wear personal protective equipment. Do not get in eyes, on skin, or on clothing. Avoid
ingestion and inhalation. Ensure adequate ventilation.

Storage Keep containers tightly closed in a dry, cool and well-ventilated place.

8. Exposure controls / personal protection

______________________________________________________________________________________________

Page 3 / 8
Methylene chloride Revision Date 17-Jan-2018
______________________________________________________________________________________________

Exposure Guidelines

Component ACGIH TLV OSHA PEL NIOSH IDLH Mexico OEL (TWA)
Methylene chloride TWA: 50 ppm (Vacated) TWA: 500 ppm IDLH: 2300 ppm TWA: 50 ppm
(Vacated) STEL: 2000 ppm
(Vacated) Ceiling: 1000 ppm
TWA: 25 ppm
STEL: 125 ppm

Legend

ACGIH - American Conference of Governmental Industrial Hygienists

OSHA - Occupational Safety and Health Administration
NIOSH IDLH: The National Institute for Occupational Safety and Health Immediately Dangerous to Life or Health

Engineering Measures Use only under a chemical fume hood. Ensure that eyewash stations and safety showers
are close to the workstation location.

Personal Protective Equipment

Eye/face Protection Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.

Skin and body protection Long sleeved clothing.

Respiratory Protection Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard
EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if
exposure limits are exceeded or if irritation or other symptoms are experienced.

Hygiene Measures Handle in accordance with good industrial hygiene and safety practice.

9. Physical and chemical properties

Physical State Liquid
Appearance Colorless
Odor sweet
Odor Threshold No information available
pH No information available
Melting Point/Range -97 °C / -142.6 °F
Boiling Point/Range 39 °C / 102.2 °F
Flash Point No information available
Evaporation Rate No information available
Flammability (solid,gas) Not applicable
Flammability or explosive limits
Upper 23 vol %
Lower 13 vol %
Vapor Pressure 350 mbar @ 20°C
Vapor Density 2.93 (Air = 1.0)
Specific Gravity 1.33
Solubility No information available
Partition coefficient; n-octanol/water No data available
Autoignition Temperature 556 °C / 1032.8 °F
Decomposition Temperature No information available
Viscosity No information available
Molecular Formula C H2 Cl2
Molecular Weight 84.93

10. Stability and reactivity

______________________________________________________________________________________________

Page 4 / 8
Methylene chloride Revision Date 17-Jan-2018
______________________________________________________________________________________________

Reactive Hazard None known, based on information available

Stability Stable under normal conditions.

Conditions to Avoid Incompatible products. Excess heat.

Incompatible Materials Strong oxidizing agents, Strong acids, Amines

Hazardous Decomposition Products Carbon monoxide (CO), Carbon dioxide (CO2), Hydrogen chloride gas, Phosgene

Hazardous Polymerization Hazardous polymerization does not occur.

Hazardous Reactions None under normal processing.

11. Toxicological information

Acute Toxicity

Product Information
Component Information
Component LD50 Oral LD50 Dermal LC50 Inhalation
Methylene chloride > 2000 mg/kg ( Rat ) > 2000 mg/kg ( Rat ) 53 mg/L ( Rat ) 6 h
76000 mg/m3 ( Rat ) 4 h
Toxicologically Synergistic No information available
Products
Delayed and immediate effects as well as chronic effects from short and long-term exposure

Irritation Irritating to eyes and skin

Sensitization No information available

Carcinogenicity The table below indicates whether each agency has listed any ingredient as a carcinogen.

Component CAS-No IARC NTP ACGIH OSHA Mexico

Methylene chloride 75-09-2 Group 2A Reasonably A3 X A3
Anticipated
IARC: (International Agency for Research on Cancer) IARC: (International Agency for Research on Cancer)
Group 1 - Carcinogenic to Humans
Group 2A - Probably Carcinogenic to Humans
Group 2B - Possibly Carcinogenic to Humans
NTP: (National Toxicity Program) NTP: (National Toxicity Program)
Known - Known Carcinogen
Reasonably Anticipated - Reasonably Anticipated to be a Human
Carcinogen
ACGIH: (American Conference of Governmental Industrial A1 - Known Human Carcinogen
Hygienists) A2 - Suspected Human Carcinogen
A3 - Animal Carcinogen
ACGIH: (American Conference of Governmental Industrial Hygienists)
Mexico - Occupational Exposure Limits - Carcinogens Mexico - Occupational Exposure Limits - Carcinogens
A1 - Confirmed Human Carcinogen
A2 - Suspected Human Carcinogen
A3 - Confirmed Animal Carcinogen
A4 - Not Classifiable as a Human Carcinogen
A5 - Not Suspected as a Human Carcinogen
Mutagenic Effects Mutagenic effects have occured in microorganisms.

Reproductive Effects No information available.

Developmental Effects No information available.

Teratogenicity No information available.

STOT - single exposure Central nervous system (CNS)

STOT - repeated exposure Liver Kidney Blood

______________________________________________________________________________________________

Page 5 / 8
Methylene chloride Revision Date 17-Jan-2018
______________________________________________________________________________________________

Aspiration hazard No information available

Symptoms / effects,both acute and Inhalation of high vapor concentrations may cause symptoms like headache, dizziness,
delayed tiredness, nausea and vomiting

Endocrine Disruptor Information No information available

Other Adverse Effects Tumorigenic effects have been reported in experimental animals.

12. Ecological information

Ecotoxicity
.

Component Freshwater Algae Freshwater Fish Microtox Water Flea

Methylene chloride EC50:>660 mg/L/96h Pimephales promelas: EC50: 1 mg/L/24 h EC50: 140 mg/L/48h
LC50:193 mg/L/96h EC50: 2.88 mg/L/15 min
Persistence and Degradability Persistence is unlikely based on information available.

Bioaccumulation/ Accumulation No information available.

Mobility Will likely be mobile in the environment due to its volatility.

Component log Pow

Methylene chloride 1.25

13. Disposal considerations

Waste Disposal Methods Chemical waste generators must determine whether a discarded chemical is classified as a
hazardous waste. Chemical waste generators must also consult local, regional, and
national hazardous waste regulations to ensure complete and accurate classification.

Component RCRA - U Series Wastes RCRA - P Series Wastes

Methylene chloride - 75-09-2 U080 -

14. Transport information

DOT
UN-No UN1593
Proper Shipping Name DICHLOROMETHANE
Hazard Class 6.1
Packing Group III
TDG
UN-No UN1593
Proper Shipping Name DICHLOROMETHANE
Hazard Class 6.1
Packing Group III
IATA
UN-No UN1593
Proper Shipping Name Dichloromethane
Hazard Class 6.1
Packing Group III
IMDG/IMO
UN-No UN1593
Proper Shipping Name Dichloromethane
Hazard Class 6.1
Packing Group III
15. Regulatory information
United States of America Inventory

______________________________________________________________________________________________

Page 6 / 8
Methylene chloride Revision Date 17-Jan-2018
______________________________________________________________________________________________

Component CAS-No TSCA TSCA Inventory notification - TSCA - EPA Regulatory

Active/Inactive Flags
Methylene chloride 75-09-2 X ACTIVE R

Legend:
TSCA - Toxic Substances Control Act, (40 CFR Part 710)
X - Listed
'-' - Not Listed
R - Indicates a substance that is the subject of a Section 6 risk management rule under TSCA.

TSCA 12(b) - Notices of Export Not applicable

International Inventories
Canada (DSL/NDSL), Europe (EINECS/ELINCS/NLP), Philippines (PICCS), Japan (ENCS), Australia (AICS), China (IECSC), Korea (ECL).

Component CAS-No DSL NDSL EINECS PICCS ENCS AICS IECSC KECL
Methylene chloride 75-09-2 X - 200-838-9 X X X X KE-23893

U.S. Federal Regulations

SARA 313
Component CAS-No Weight % SARA 313 - Threshold
Values %
Methylene chloride 75-09-2 >99.5 0.1

SARA 311/312 Hazard Categories See section 2 for more information

CWA (Clean Water Act)

Component CWA - Hazardous CWA - Reportable CWA - Toxic Pollutants CWA - Priority Pollutants
Substances Quantities
Methylene chloride - - X X

Clean Air Act

Component HAPS Data Class 1 Ozone Depletors Class 2 Ozone Depletors
Methylene chloride X -

OSHA - Occupational Safety and

Health Administration

Component Specifically Regulated Chemicals Highly Hazardous Chemicals

Methylene chloride 125 ppm STEL -
12.5 ppm Action Level
25 ppm TWA
CERCLA This material, as supplied, contains one or more substances regulated as a hazardous
substance under the Comprehensive Environmental Response Compensation and Liability
Act (CERCLA) (40 CFR 302)

Component Hazardous Substances RQs CERCLA EHS RQs

Methylene chloride 1000 lb 1 lb -
California Proposition 65 This product contains the following proposition 65 chemicals

Component CAS-No California Prop. 65 Prop 65 NSRL Category

Methylene chloride 75-09-2 Carcinogen 200 µg/day Carcinogen
50 µg/day
U.S. State Right-to-Know
Regulations
Component Massachusetts New Jersey Pennsylvania Illinois Rhode Island
Methylene chloride X X X X X

______________________________________________________________________________________________

Page 7 / 8
Methylene chloride Revision Date 17-Jan-2018
______________________________________________________________________________________________

U.S. Department of Transportation

Reportable Quantity (RQ): Y
DOT Marine Pollutant N
DOT Severe Marine Pollutant N

U.S. Department of Homeland This product does not contain any DHS chemicals.
Security

Other International Regulations

Mexico - Grade No information available

16. Other information

Prepared By Regulatory Affairs
Thermo Fisher Scientific
Email: EMSDS.RA@thermofisher.com

Creation Date 27-Jan-2010

Revision Date 17-Jan-2018
Print Date 17-Jan-2018
Revision Summary This document has been updated to comply with the US OSHA HazCom 2012 Standard
replacing the current legislation under 29 CFR 1910.1200 to align with the Globally
Harmonized System of Classification and Labeling of Chemicals (GHS).

Disclaimer
The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the
date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage,
transportation, disposal and release and is not to be considered a warranty or quality specification. The information
relates only to the specific material designated and may not be valid for such material used in combination with any other
materials or in any process, unless specified in the text

End of SDS

______________________________________________________________________________________________

Page 8 / 8