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    PhysioEx Exercise 4 Activity 4 - Balamad, Maria Karla M.

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    Maria Karla Balamad
    The document describes an experiment measuring cortisol and adrenocorticotropic hormone levels in patients. It includes pre-lab and post-lab quiz results, experiment data on hormone levels in 5 patients, and a review sheet assessing the results. The document provides information on the hormonal regulation of cortisol and conditions related to abnormal cortisol levels.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd

    PhysioEx Exercise 4 Activity 4 - Balamad, Maria Karla M.

    Uploaded by

    Maria Karla Balamad
    23 views3 pages
    The document describes an experiment measuring cortisol and adrenocorticotropic hormone levels in patients. It includes pre-lab and post-lab quiz results, experiment data on hormone levels in 5 patients, and a review sheet assessing the results. The document provides information on the hormonal regulation of cortisol and conditions related to abnormal cortisol levels.

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    PhysioEx Exercise 4 Activity 4_Balamad, Maria Karla M.

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    The document describes an experiment measuring cortisol and adrenocorticotropic hormone levels in patients. It includes pre-lab and post-lab quiz results, experiment data on hormone levels in 5 patients, and a review sheet assessing the results. The document provides information on the hormonal regulation of cortisol and conditions related to abnormal cortisol levels.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    23 views3 pages

    PhysioEx Exercise 4 Activity 4 - Balamad, Maria Karla M.

    Uploaded by

    Maria Karla Balamad
    The document describes an experiment measuring cortisol and adrenocorticotropic hormone levels in patients. It includes pre-lab and post-lab quiz results, experiment data on hormone levels in 5 patients, and a review sheet assessing the results. The document provides information on the hormonal regulation of cortisol and conditions related to abnormal cortisol levels.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 3

    5/10/22, 8:57 AM PhysioEx Exercise 4 Activity 4

    PhysioEx Lab Report


    Exercise 4: Endocrine System Physiology
    Activity 4: Measuring Cortisol and Adrenocorticotropic Hormone
    Name: Maria Karla M. Balamad
    Date: 10 May 2022
    Session ID: session-f8519787-9ff7-9ebf-f4fd-7cf4b513da53

    Pre-lab Quiz Results


    You scored 100% by answering 5 out of 5 questions correctly.

    1 Cortisol

    You correctly answered: is a hormone important in the body's response to stress.

    2 ACTH

    You correctly answered: is a tropic hormone that stimulates cortisol release.

    3 CRH

    You correctly answered: has a tropic effect on the anterior pituitary gland.

    4 Cushing's syndrome refers to

    You correctly answered: a hypercortisolism, which could be iatrogenic.

    5 A condition of hypocortisolism

    You correctly answered: refers to low levels of cortisol in the blood.

    Experiment Results
    Predict Questions
    No Predict Questions
    Stop & Think Questions
    1 Normally high levels of cortisol would inhibit release of

    You correctly answered: both ACTH and CRH.

    2 Which hormone(s) stimulate(s) the pituitary gland to release ACTH?

    You correctly answered: CRH.

    Experiment Data
    https://media.pearsoncmg.com/bc/bc_0media_ap/physioex/10/ex4/act4/ 1/3
    5/10/22, 8:57 AM PhysioEx Exercise 4 Activity 4

    Patient Cortisol High or low ACTH (pg/ml) High or low


    (mcg/dl)
    1 3.17 Low 19.20 Low
    2 30.73 High 11.41 Low
    3 47.10 High 82.50 High
    4 2.89 Low 100.14 High
    5 51.36 High 17.10 Low

    Table 4.1 Cortisol and ACTH Disorders


    Cortisol Level ACTH Level
    Cushing's syndrome (primary
    High Low
    hypercortisolism)
    latrogenic Cushing's
    High Low
    syndrome
    Cushing's disease (secondary
    High High
    hypercortisolism)
    Addision's disease (primary
    Low High
    adrenal insufficiency)
    Secondary adrenal
    Low Low
    insufficiency (hypopituitarism)

    Post-lab Quiz Results


    You scored 100% by answering 6 out of 6 questions correctly.

    1 Under normal conditions, if the amount of secreted CRH increases, then

    You correctly answered: the amount of secreted ACTH will increase.

    2 Under normal conditions, if the amount of secreted ACTH increases, then

    You correctly answered: the amount of secreted CRH will likely decrease.

    3 Under normal conditions, if the amount of secreted cortisol increases, then

    You correctly answered: the amount of secreted ACTH will likely decrease.

    4 If a hypersecreting pituitary tumor develops, then an expected outcome is

    You correctly answered: a diagnosis of Cushing's disease.

    5 If a hypersecreting adrenal cortex tumor develops, then an expected outcome is

    You correctly answered: abnormally low levels of CRH due to negative feedback.

    https://media.pearsoncmg.com/bc/bc_0media_ap/physioex/10/ex4/act4/ 2/3
    5/10/22, 8:57 AM PhysioEx Exercise 4 Activity 4

    6 A patient's chart lists the diagnosis of Addison's disease. Therefore, you expect

    You correctly answered: abnormally high levels of ACTH.

    Review Sheet Results


    1 Which patient would most likely be diagnosed with Cushing's disease (view Table 4.1 in
    Experiment Results)? Why?

    Your answer:

    Patient 3 would likely be diagnosed with Cushing's disease because they exhibit high cortisol
    and ACTH levels in the bloodstream.

    2 Which two patients have hormone levels characteristic of Cushing's syndrome (view Table
    4.1 in Experiment Results)?

    Your answer:

    Patient 2 and 5 exhibit signs of Cushing's syndrome.

    3 Patient 2 is being treated for rheumatoid arthritis with prednisone. How does this
    information change the diagnosis (view Table 4.1 in Experiment Results)?

    Your answer:

    Prednisone reduces the levels of cortisol in the blood by suppressing the function of the
    adrenal gland. Therefore, this would decrease the ability for cortisol to be released when
    stimulated by ACTH that confirms the experimental result.

    4 Which patient would most likely be diagnosed with Addison's disease (view Table 4.1 in
    Experiment Results)? Why?

    Your answer:

    Patient 4 because of the low level of cortisol and the ACTH is high. This shows signs of
    primary adrenal insufficiency because the low level of cortisol caused by damage to the
    anterior pituitary and ACTH is elevated to compensate.

    https://media.pearsoncmg.com/bc/bc_0media_ap/physioex/10/ex4/act4/ 3/3

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