MS Ijbpas 2021 5577
MS Ijbpas 2021 5577
MS Ijbpas 2021 5577
ISSN: 2277–4998
Shri Gajanan Maharaj Shikshan Prasarak Mandal’s Sharadchandra Pawar College of Pharmacy,
https://doi.org/10.31032/IJBPAS/2021/10.7.5577
ABSTRACT
In this review endeavour has been made to study the ancient modern concordance of Shata Dhuta
Ghrita along with its multidisciplinary applications. Shata Dhauta Ghrita is an ancient cream
with magical beautification properties. It is certified by science for its supreme skin-healing
benefits & Ayurveda defines it as supreme skin elixir. A cooling, super-light cream and powerful
anti-aging formula, Shata Dhauta Ghrita is an anti-inflammatory skin solution & a beautifying
skin agent. As specified in Ayurveda's classical text Charaka Samhita, Shata Dhauta Ghrita is
made in pure copper vessel by washing pure cow ghee 100 times in the aura of divine mantra
chants. Shata Dhauta Ghrita is a light cream that deeply penetrates into all seven layers of skin to
heal it from within. It keeps skin silky, smooth & wrinkle-free. It protects against sun-damage &
heals age-spots. Its light texture & silky-smooth feel feels heavenly on skin. Shata Dhauta Ghrita
helps shrink the pores & is a super skin food for all skin types.
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INTRODUCTION
The ritual of extracting Shata Dhauta and impacts the aura of the outer layer and
Ghrita accentuates sensitivity to the sun.
Shata Dhauta Ghrita is a result of an ancient Shweta
Ayurvedic ritual of washing cow ghee This is a white layer, and it provides balance
(clarified butter) 100 times with purified to skin color, lightening the darker colors of
water in a copper vessel while chanting vedic the inner layers.
mantras. The result is butter like odorless Tamra
silky cream which has the incredible property This layer nurtures the upper layers of the
of penetrating all the seven layers of the skin skin. It supports the immune system. This is
without blocking the pores [1]. the layer that helps the skin perform its
The Seven Layers of your Skin function of being a “barrier.”
Ayurveda describes seven distinct layers of Vedini
the skin, each with its own structure and This fifth layer sensually links the skin to the
function. The skin as a whole is able to rest of the body. It is the center for
effectively perform its overall functions transformation of sensation — feeling of
when all the seven layers are healthy [2, 3]. pain, for example.
Avabhasini Rohini
This is the outermost layer. It reflects the This layer upholds recuperating and
complexion and aura of the individual. recovery. A fruitful nutritional diet routine
Internal and external moisturization restores supports this layer.
the health and appearance of this layer of the Mamsadhara
skin. This deepest layer is the stage for the skin's
Lohita soundness and solidness. At the point when
This layer supports the outermost layer. It this layer is in balance, the skin looks
indicates the quality of Rakta Dhatu (blood) youthful and flexible.
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Shata Dhauta Ghrita – A background cow. It was initially found in the heavenly
Ayurveda and its prizes resemble a Atharva Veda.
tremendous sea. Panchagavya, 5 of Unadulterated ghee from cows is washed
Ayurvedic fixings that are easily recognized multiple times in a copper vessel while
names now and acquired from cow (Milk, mantras are being recited. Reciting of
Curd, Ghee, Urine and Dung) have huge part Mantras helps tune into the force inside and
in illness the executives. Every one of the its reverberation channelizes every one of the
items have monstrous number of advantages. energies and positive vibrations in the item.
With regards to skin, the most solid and Each wash makes the ghee lighter and causes
sought after item is GHEE. a ton of different changes in its synthetic
It's utilized in different structures in the properties. The way toward washing in the
Ayurvedic healthy skin system. copper vessel works with the blending of
Notwithstanding, outstanding amongst other copper in the combination, expanding its
the revered Ayurvedic method is Shata properties. The trademark smell, granular and
Dhauta Ghrita or multiple times washed slick consistency in cow ghee no longer
ghee. Shata Dhauta Ghrita is multiple times remaining parts in Shata Dhauta Ghrita. It
washed explained butterfat, which has been turns into a homogeneous, smooth, non-slick
gotten from milk from unadulterated desi item which is simpler to apply.
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With each wash, the substance goes through consumes critical space in the space of
various compound and actual changes. The medical services. Regardless of this, the
expanded copper content in the item commitment of the conventional frameworks
recuperates scars and furthermore gives it a of medication to medical care keeps on being
calming property. Shata Dhauta Ghrita is tremendous. The adequacy of conventional
useful in getting gleaming skin, yet can arrangements, which are regularly
likewise be utilized to treat an assortment of polyherbal, is expanding a direct result of the
other skin-related issues. The increment in overall impression that these items are
dampness content because of washing is amiable. The single particle based
useful for hydration and cooling impact on medications utilized in allopathic framework
skin. The greatest and most extraordinary can have extreme unfavorable impacts.
property that the item soaks up from being Panchagavya, for example 5 items acquired
washed in a copper vessel is that it is the lone from (cow milk, curd, ghee, pee and
compound that infiltrates through every one fertilizer) referenced in Ayurveda have huge
of the 7 layers of the skin. The Products are job in illness the executives. Cow ghee is
made while reciting so vibrations are having different exercises without anyone
invested in the item thus by your skin. Every else and furthermore by definitions created
item clings to the best expectations of virtue, utilizing cow ghee. For instance, impact of
credibility and quality. Aside from customary Bramhi ghrita on CNS, narcotic and
skin issues, SDG can likewise fix dermatitis, anticonvulsant action of Unmadnashak
rosacea, and pimples. Along these lines it is ghrita, wound mending action of Darvhi
the healthy answer for all your skin issues [4, ghrita, wound recuperating movement of
5]. Hingvadya ghrita, mitigating action of
Customary arrangement of medication, Jatyadi ghrita, and so on Shata-dhauta-ghrita
advanced over the ages, had been totally (SDG) is multiple times washed (shata = 100,
taking care of the medical care of the world dhauta = washed) explained butterfat. It is
until the approach of allopathic arrangement referenced in customary writings for the
of medication. As this framework utilized administration of conditions like consumes,
information on present day science and chicken pox, scars, wounds, herpes,
science, for both revelation and treatment, it infection, and other skin sicknesses and as a
discovered quick adequacy and now vehicle for medications to be applied
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remotely. In the investigation, the Ayurvedic utilizing cow ghee. For instance, impact of
planning has been assessed for its Bramhi ghrita on CNS, narcotic and
physicochemical boundaries and changes anticonvulsant movement of Unmadnashak
happening during washing were examined. ghrita, wound mending action of Darvhi
An endeavor is made to discover the ghrita, wound recuperating action of
reasoning behind washing cow ghee multiple Hingvadya ghrita, mitigating action of
times with water Traditional arrangement of Jatyadi ghrita, and so on Shata-dhauta-ghrita
medication, advanced over the ages, had (SDG) is multiple times washed (shata = 100,
been totally caring for the medical services of dhauta = washed) explained butterfat. It is
the world until the coming of allopathic referenced in conventional writings for the
arrangement of medication. As this administration of conditions like consumes,
framework utilized information on current chicken pox, scars, wounds, herpes,
science and science, for both disclosure and infection, and other skin sicknesses and as a
treatment, it discovered quick worthiness and vehicle for medications to be applied
now consumes huge space in the space of remotely. In the examination, the Ayurvedic
medical services. Despite this, the readiness has been assessed for its
commitment of the customary frameworks of physicochemical boundaries and changes
medication to medical care keeps on being happening during washing were investigated.
colossal. The adequacy of conventional An endeavor is made to discover the
arrangements, which are ordinarily reasoning behind washing cow ghee multiple
polyherbal, is expanding a result of the times with water [6, 7].
overall impression that these items are Methods of Preparation
kindhearted. The single particle based Samskara assumes a significant part in all
medications utilized in allopathic framework definitions in changing the medication into
can have extreme antagonistic impacts. wanted dose structure with better helpful
Panchagavya, for example 5 items acquired worth. Shatadhouta Ghrita is one such novel
from (cow milk, curd, ghee, pee and Ayurveda readiness and a model for Dhauta
compost) referenced in Ayurveda have huge samskara, Jala samskara and Agni
job in sickness the board. Cow ghee is having samskara. It is set up by two techniques. In
different exercises without help from anyone one technique Ghrita (Ghee) is warmed,
else and furthermore by definitions created poured in chilly water and remembering
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Ghrita for multiple times. In second strategy Multiple times. Vaidayak Shabda Sindukara
Ghrita is washed with water for multiple has explained one more reference about the
times. The Pharmaceutical investigation preparation of Shatadhouta Ghrita by
showed stamped contrasts in actual Santapya (Heating) the Ghrita and
boundaries and distinction in planning time Nirvapana (Pouring) in Sita Jala (Cold
was likewise seen in this examination [8]. water) for one hundred times. This method is
Samskara is a procedure adopted in seldom used in pharmaceutics practice and is
pharmaceutics to induce the therapeutic not popular. Hence, an attempt was made to
properties, thereby enhancing the potency compare pharmaceutical preparation of
and bioavailability of the drugs involved. Shatadhouta Ghrita by both the methods and
Samskaro hi naama Gunantaradhanam understand the pharmaceutical changes that
Uchyate. The methods by which the occur by preparing it and it was carried out
properties like Rasa, Guna, Virya, Vipaka, for ten times with Sagni and Niragni method
undergo “Gunantaradhaanam” i.e the [9-12].
changing of Sthoola Guna (macro form) to Method of preparation of Shatadhauta
Sukshma Guna (micro form); there is Ghrita: - The whole procedure was divided
transformation of physical as well as in two methods.
chemical properties within the Dravya Method A - Preparation of Shatadhauta
(Substance). Shatadhouta Ghrita is an Ghrita by Sagni method
Ayurvedic arrangement, ordinarily Method B – Preparation of Shatadhauta
recommended for treatment of skin Ghrita by Niragni method
conditions. As the name indicates, it is set up Method A
by washing Ghee multiple times with water. Desired amount of Ghrita (50 g) was taken
This methodology changes the ghee into a in steel vessel and started heating on gas
delicate, cooling, supporting, plush treatment stove from a distance of 4 cm to give
that is utilized as a customary lotion and Mandagni.
hostile to wrinkle skin cream. Shatadhauta Once Ghrita melted and started boiling it
Ghrita is set up by washing the Ghrita with was poured in cold water having temperature
water till the water turns warm and afterward of 22oC.
the warm water is disposed of and new water Once Ghrita got cool, it settled over the
is added and the cycle is rehashed for water in the form of a layer.
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After self cooling Ghrita was collected with glass with some pressure till increase in
the help of a spoon/ spatula. temperature of water was observed.
Some watery portion came along with Once temperature was increased, water was
spoon that was removed manually. taken out and it was measured.
Again, the same Ghrita was given mild heat Again fresh water was poured and the same
(Mandagni) till it reached a state where the process was repeated for ten times.
water started to splash. Both the methods are easy for the preparation
Again it was poured in cold water of Shatadhauta Ghrita. But from
temperature of 22 0C. pharmaceutical point of view Method A
This process was repeated for ten times. (Heating method) the yield is less; time
Method B consumption is more and requires heating
Desired amount of Ghrita (50g) was taken process is required rather than Method B
Desired amount of cold water (100 ml) was carried out to compare the constituent
poured till the Ghrita fully immersed in changes occurring in the Ghrita in both
The temperature was noted of the Ghrita scope to revalidate the efficacy and safety of
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about as an impetus to advance fat parting. in cool water (240C). It brings about the
The above speculation of fat parting by arrangement of oil in water (o/w) emulsion.
utilizing enormous overabundance of fluid Since while pouring the hot dissolved Ghrita
stage can be connected with washing cow in chilly water the Ghrita is separated into
ghee multiple times with water. It very well globules which indicate Ghrita as scattered
may be called attention to that by washing stage and water means as constant stage.
cow ghee multiple times with water, the fatty Melted Ghrita became solid and accumulated
oils are splitted into glycerol and free over the surface of water. That ghrita was
unsaturated fats. The reduction in corrosive taken out and there was 5 g increase in
worth can be connected with the reality of fat weight during 1st Dhauta. The reason may be
parting in to glycerol and unsaturated fats, the passage of water globules in fat
which are eliminated alongside the fluid molecules by forming water oil (w/o)
stage. From the current work, it very well emulsion. Here water molecules are
may be reasoned that changes occurring in considered as dispersed phase and fat
cow ghee while washing it with water molecules (Ghrita) are considered as
multiple times to plan Shata-dhauta-ghrita, continuous phase. The utilization of energy
makes it a rich and appropriate item for as warmth, mechanical unsettling is needed
effective application. Notwithstanding, there to decrease the inner stage in little drops.
is a need to do additionally concentrate on its Warming is a compelling method of breaking
soundness, pharmacological assessment as a practically every one of the connections
powerful effective item and its plan between the particles of a fluid. In technique
improvement [15, 16]. A, Ghrita was warmed so there might be
DISCUSSION shortcoming or breakage of bonds in the
Shatadhauta Ghrita is a unique Ayurvedic atoms of Ghrita and when Ghrita interacts
formulation utilized for the treatment of with water fat parting cycle may happens. At
wounds, burns, skin illnesses and so forth it the point when the liquefied Ghrita was filled
is an illustration of emulsion where Ghrita virus water out of nowhere it spread over the
and water are in immiscible fluid, one of outside of water in light of the fact that the
which is dispersed as minute globules into thickness of water is more than thickness of
the other. Ghrita and there is an inconsistent appealing
In Method A, Ghrita was warmed and poured power among water and Ghrita particles.
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After first Dhauta sprinkling of Ghrita was like w/o/w emulsion. The explanation might
seen during warming Ghrita. Since some be section of water globules in fat particles
water divides consistently come during by framing water oil (w/o) emulsion and
recalling the Ghrita after each Dhauta. prompts expanding of Ghrita.
During heat, water at the lower part of the In Method B, during pulverizing normal
vessel being warmed quickly transforms into 2.20C temperature was expanded and there is
steam and structures cavitations in Ghrita. rehashed and delayed tritutation of the fat
Because of pressing factor created by heat it and water combination. In this manner, the
shoots up with a sound and is named as temperature and pressing factor might be
sprinkle. In Method B, Ghrita was ground up contributing for fat parting (Figure 1). The
alongside water and in this way development yellow coloring arrives from beta carotene in
of water oil (w/o) sort of emulsion since the cow's butterfat. Due to heating and again
water is in scattered stage and oil is in washing with water the pigment may leak out
constant stage. As the washing proceeds, into water and change in the colour takes
because of pressing factor applied during place after washing (Dhauta). Method A,
fomentation, molecule size of fat granules Dhauta Ghrita was more whitish than
gets decreased (according to surface it was Method B. Because in Method A, heat is the
non granular and smooth). In the long run, additional factor which may facilitates rapid
progressive washings bring about o/w sort of expulsion of beta carotene from Ghrita than
emulsion. It is conceivable that it may Method B.
prompt development of a complex system
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The benefits of Shata Dhauta Ghrita shelf-life of all SDG is usually 18 months
Shata Dhauta Ghrita is unbelievingly potent after which the goodness of oils in it may
when it comes to repairing damage caused to begin to evaporate. It shall be stored away
the skin by pollution and sun-exposure. This from moisture and keep refrigerated for
silky cream is then mixed with ayurvedic longer shelf-life [17, 18].
herbs like Avabhasini, Lohita, Shweta, Advantages
Tamra, Vedini, Rohini, Mamsadhera etc. and 1. Authentic and Organic Ingredients
an earthy fragrance that leave your skin and 2. Purely Vegetarian
hair feeling naturally nourished and repaired. 3. Alcohol Free
Authentic and Raw Fragrance 4. Chemical Free
Shata Dhauta Ghrita may sometimes contain 5. Completely Natural
mild negligible scent of ghee that dissipates 6. Cruelty Free
immediately after application. All these 7. Free from Preservatives
ingredients are 100% natural & sourced from 8. Traditionally Accepted
organic resources. The authentic and raw 9. Known for Purity
fragrance of the SDG is the hallmark of its 10. Applicable to Modern Cosmetic
purity. The earthy and natural smell that World [19, 20].
emanates from SDG is really enjoyable. The
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where Ghrita and water are immiscible. Oil- Ghrita: Development and evaluation with
water (o/w) emulsions are generally valuable reference to Murcchana and Shata-
as water-launderable medication bases and Dhauta process. Journal of Ayurveda and
for general corrective reason. Water-oil (w/o) integrative medicine, 11(3), 2020: 261-
emulsions are utilized all the more generally 269.
for the treatment of dry skin and emollient [5] Nikam, S. T. Study of Karpoor Ghrita
applications. Thus, from this review, it can and Povidine Iodine in Sadyo Vrana.
be concluded that the shata dhruta ghrita International Journal of Ayurvedic
finds its modern applications in Wound Medicine, 6(4), 2015: 329-334.
Healing, anti-inflammatory activities of [6] Pande, V. V., Patel, V. P., Zarekar, N. S.,
active pharmaceutical ingredients in form of Pandit, S. R., & Pote, A. K. Investigation
various nanoformulations. More research of Effects of Shata Dhauta Ghrita on The
endeavours are required to determine the Skin Permeation of Fluconazole Loaded
various pharmacological as well as Topical Antifungal Nanolipogel. Journal
pharmaceutical applications of Shata Dhruta of Pharmaceutical Sciences and
Ghrita in modern pharmaceutical era. Research, 12(7), 2020: 948-956.
REFERENCES [7] Babu, B., Ravi, M., Kumar, A. B.,
[1] Kashinath S. Chaturvedi Gorakhnath Sudheendra, V. H., & Ravishankar, B.
edited Charak Samhita of Agnivesha. Burn wound healing potential of Plain
Revised by Charak and Dridhabala, Part gritha, Shatadhauta ghrita and
II, Chaukhamba Bharati Academy, Sahasradhauta ghrita on wistar albino
Varanasi, Reprint. 2009:75-6. rats, IJTK, 14(2) 2015: 273-278.
[2] Parihar BK, Thomas S, Hussain G, [8] Majumdar, S. H., Kulkarni, A. S.,
Kadibagil VR, Lakshkar A. Aloorkar, N. H., & Shinde, M. D.
Pharmaceutical Study of Shatadhauta Exploring Shat Dhaut Ghrita As
Ghrita Prepared By Two Different Formulation Base For The Topical
Methods. 5 (5), 2016: 1769-1778. Delivery of Curcuma amada, Indo
[3] Deshpande S, Deshpande A, Tupkari S, American Journal of Pharmaceutical
Agnihotri A. Shata-dhauta-ghrita–A case Research, 2016: 6243-6249.
study. IJTK, 8(3), 2009: 387-391. [9] Potdar, M., Usman, M. R. M., Salgar, S.
[4] Wayal, S. R., & Gurav, S. S. Bhallatakadi D., Sali, L. P., & Hameed, M. A. M. A
2428
IJBPAS, July, 2021, 10(7)
Pulate C et al Review Article
novel natural permeation enhancer for rats. Research Journal of Pharmacy and
famcicovir cream. Int J Int Sci Inn Tech, Technology, 13(3), 2020: 1377-1385.
1(3), 2012: 15-18. [15] Jamir, A., Gauttam, J., Prasanth, D., &
[10] Ravindra, R. P., & Muslim, P. K. Bhatted, S. K. An Ayurvedic
Comparison of physical characteristics Multimodular Treatment Of Alopecia
of vanishing Cream base, cow ghee and Totalis (Khalitya) With Respect To
shata-dhauta-ghrita as per Panchakarma: A Case Report.
pharmacopoeial standards. International International Journal of Ayurveda and
Journal of Pharma and Bio Sciences, Pharma Research, 2019: 25-33.
4(4), 2013: 14-21. [16] Prajakta, S., & Shahu, K. Formulation
[11] Sakhare, M. P., Dakshinkar, N. P., and Evaluation of Vanishing Herbal
Kurkure, N. V., Upadhye, S. V., Bhojne, Cream of Crude Drugs. Asian Journal of
G. R. Determination of chemical Pharmaceutical Research and
composition of Panchgavya ghrita and Development, 8(3), 2020: 66-69.
garlic pill using gas chromatography and [17] Prajapati, P. K., Sharma, R., Amrutia,
mass spectrometry (GC-MS). TIC, 1, A., & Patgiri, B. J. Physicochemical
2021: E9. screening and shelf life evaluation of
[12] Raut, A. A., & Vaidya, A. D. Kuṅkumādi Ghṛta prepared using Kesara
Panchgavya and cow products: A trail and Nāgakesara. Ancient science of life,
for the holy grail. Journal of Ayurveda 36(3), 2017: 129.
and integrative medicine, 9(1), 2018: 64- [18] Satish, H. S., Rashmi, T. M.,
66. Thirunavukkarasu, M. S., Mithun, B., &
[13] Dhase, A. S., Khadbadi, S. S., & Saboo, Narmada, M. G. Sushruta’ s eight
S. S. Formulation and evaluation of pearls for Infective Ulcer. Journal of
vanishing herbal cream of crude drugs. Ayurveda and Integrated Medical
AJEthno, 1, 2014: 313-8. Sciences, 2(5), 2017: 142-153.
[14] Moholkar, S. A., Mukherjee-Kandhare, [19] https://www.alyuva.in/2020/01/09/shata-
A. A., Worlikar, P. S., & Tilak, A. dhauta-ghrita-a-background/
Synergistic Potential of Honey and [20] https://scholar.google.com/scholar?hl=en
Shatdhaut Ghrut in the management of &as_sdt=0%2C5&q=shata+dhauta+ghru
Diabetic Foot Ulcer in the Experimental ta&oq=
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