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q4 Wk4 Cancer

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CANCER

CANCER
• Cancer refers to any of many diseases characterized
by the development of abnormal cells that divide
uncontrollably and can penetrate and destroy normal
human cells and tissues.
• Cancer is the second-leading cause of death in the
world. But survival rates are improving for many types
of cancer, thanks to improvements in cancer screening
and cancer treatment.
WHEN WILL A
PERSON CAN
HAVE CANCER?
Difference between Normal
Cells and Cancer Cells.
Normal Cells Cancer Cells
Growth

Normal cells Cancer cells don’t stop


reproduce only growing and dividing
even when there are
when and where enough cells already
it’s needed and present, and this
stop reproducing continuous growth often
when enough cells results in tumors (a
are present. cluster of cancer
cells) being formed.
Normal Cells Cancer Cells
Cell Repair and Death

Normal cells are Cancer cells are


either repaired or either not repaired
undergo apoptosis or do not undergo
(cell death) when apoptosis.
they are damaged
or too old.
Normal Cells Cancer Cells
Ability to Spread

Normal cells stay in Cancer cells may lack


the body where they the resistance
are supposedly molecules that cause
located. For example, adhesiveness and are
cardiac muscle cells able to disconnect and
remain in the heart. perform metastasis- the
spreading of cancer
cells to other areas of
the body through the
bloodstream or
lymphatic system.
Cancer Cells
Appearance

Cancer cells look


different as observed
under the microscope, not
unlike normal cells.
Cancer cells often exhibit
much more variability in
cell size, some are larger
than normal, and some are
smaller than normal.
Difference between Benign and
Malignant Cancer
• Benign the tumor is not cancerous. They won’t invade
nearby cells. Although they can cause serious
problems when they grow near organs, press on a
nerve cell, or restrict blood flow. But usually, benign
tumors respond well to treatments.
• On the other hand, Malignant tumors are cancerous
they can grow quickly and have irregular borders, they
often invade surrounding tissue.
TYPES OF CANCER
What are the risk
factors and causes of
cancer?
01
Causes of Cancer
Causes of Cancer
1. Genetic Mutation- A gene mutation can instruct a healthy
cell to allow rapid growth, failed to stop uncontrolled cell
growth, make mistakes when repairing DNA errors.
2. Risk Factors - It is usually not possible to know exactly why
one person develops cancer and another doesn't. But research
has shown that certain risk factors may increase a person's
chances of developing cancer. This includes: Lifestyle factors,
Family history, inheritance, and genetics may play an
important role in some childhood cancers, exposure to certain
viruses, environmental exposures, radiation.
RISK FACTORS
● Age: Although people of all ages can get
cancer, older people are at greater risk.
● Genetics: The history of the family will put
you at risk for cancer. You could be more at
risk for that form of cancer if you or anyone
in the family had a similar type of cancer.
For certain cancers, such as breast cancer and
colon cancer, genetics plays a major part.
RISK FACTORS
● Behaviors: Tobacco use and exposure to the sun or
other sources of UV radiation are risk factors for
cancer. Other lifestyle choices that might affect
the chances of getting cancer include a poor diet,
lack of exercise, or heavy drinking.
● Viruses or bacteria: There is a virus or bacteria
that trigger certain cancers. The human
papillomavirus (HPV), which causes cervical cancer,
hepatitis B and C viruses, which can cause liver
cancer, and the EpsteinBarr virus, which can cause
a form of lymphoma, are several cancer associated
viruses. Likewise, the Helicobacter pylori can
cause gastric cancer
RISK FACTORS

● Exposure to chemicals: As we have discussed, being


exposed to chemicals may also be a risk factor.
● Radiation of certain wavelengths, called ionizing
radiation, has enough energy to damage DNA and
cause cancer. Ionizing radiation includes radon, x-
rays, gamma rays, and other forms of high-energy
radiation. Lower-energy, non-ionizing forms of
radiation, such as visible light and the energy
from cell phones, have not been found to cause
cancer in people. UV rays can also damage the DNA
in our skin cells and lead to skin cancer.
RISK FACTORS
RISK FACTORS
01
Activity
On a short bond paper, make a slogan
showing public awareness about cancer and how
to reduce the risk of getting this disease.

Rubrics:
Content: 10
Creativity: 10
Time Management: 5
Total: 25
CARCINOGENS
Carcinogens and Carcinogenesis
● Carcinogens are any of several agents,
substances, and even radiation that can cause
cancer in humans. It may be a substance in the
air, a product you use, or a chemical in foods
and drinks.
● Carcinogenesis also oncogenesis or
tumorigenesis is the process by which normal
cells are transformed into cancer cells.
01
Three Major Categories of
Carcinogens
Chemical Carcinogens
● Chemical Carcinogens result from
exposures in the form of chemicals
that are often encountered in the
environment or through our life and
diet.
● Example: Tobacco Smoking which can
cause lung cancer.
Physical Carcinogens
● Physical Carcinogens are particles of
soft or hard material that are not
soluble in water. They exist as a
solid compound.
● Ionizing radiation is an example of a
radioactive carcinogen, as is found in
UV light and medical x-rays and from
radioactive materials in the industry
and the general environment.
Oncogenic Virus or Oncovirus
● Oncogenic Virus or Oncovirus is the
virus that can cause cancer. (cancer-
causing) viruses.
● Examples are Hepatitis C Virus,
Hepatitis B Virus, Human
Papillomavirus, Human Herpesviruses.
01
Common Carcinogens
01
Activity
List at least two (2) carcinogenic substances or
factors, how does it affect the human body, what is possible
cancer be acquired and how can it be prevented.
THANK YOU
FOR
LISTENING! ☺

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