Wash buffer 1

Safety Data Sheet SDS n°81

according to Regulation (EC) No. 1907/2006 (REACH) with its amendment Regulation (EU) 2020/878
Revision 05 - Revision date: 08/02/2024 – CC22-109

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1. Product identifier

Product form Mixture
Trade name Wash buffer 1

1.2. Relevant identified uses of the substance or mixture and uses advised against
1.2.1. Relevant identified uses
Use of the substance/mixture : For in vitro diagnostic use.

1.2.2. Uses advised against

Restrictions on use : Any other use other than that indicated as relevant.

1.3. Details of the supplier of the safety data sheet

ElitechGroup Spa
C.so Svizzera 185
10149 Torino
Italy
T +39 011 97.61.91 - F +39 011 93.676.11
E-mail address of competent person responsible for the SDS : s.fazari@elitechgroup.com

1.4. Emergency telephone number

Emergency number : +39 011 97.61.91 (Office time: monday – friday; 8:30-13; 14:00-17:30; language spoken: italian)

Country/Area Organism/company Address Emergency number Comments

Italy Centro Antiveleni di Bergamo Piazza OMS - Organizzazione +39 800 88 33 00
Azienda Ospedaliera Papa Giovanni XXII Mondiale della Sanità, 1
24127 Bergamo

Italy Centro Antiveleni di Milano Piazza Ospedale Maggiore 3 +39 02 6610 1029
Ospedale Niguarda Ca' Granda 20162 Milano

Italy Centro Antiveleni di Roma Largo Agostino Gemelli, 8 +39 06 305 4343
CAV Policlinico "A. Gemelli", Dipartimento 00168 Roma
di Tossicologia Clinica
Universita Cattolica del Sacro Cuore

Italy Centro Antiveleni di Roma Viale del Policlinico, 155 +39 06 4997 8000
CAV Policlinico "Umberto I", Università di 00161 Roma
Roma

Italy Centro Antiveleni di Firenze Largo Brambilla, 3 +39 055 794 7819
Az. Osp. "Careggi" U.O. Tossicologia 50134 Firenze
Medica, S.O.D. di Tossicologia
Clinicaicologia Clinica

Italy Centro Antiveleni di Pavia Via Salvatore Maugeri, 10 +39 03 822 4444
CAV Centro Nazionale di Informazione 27100 Pavia
Tossicologica, Istituti Clinici Scientifici
Maugeri Spa

Italy Centro Antiveleni di Roma Piazza Sant’Onofrio, 4 +39 06 6859 3726

CAV “Osp. Pediatrico Bambino Gesù” 00165
Dip. Emergenza e Accettazione DEA

Italy Centro Antiveleni di Foggia Viale Europa, n.12 +39 800 183 459
Az. Osp. Univ. Foggia 71122 Foggia

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 Wash buffer 1
Safety Data Sheet SDS n°81
according to Regulation (EC) No. 1907/2006 (REACH) with its amendment Regulation (EU) 2020/878
Revision 05 - Revision date: 08/02/2024 – CC22-109

Country/Area Organism/company Address Emergency number Comments

Italy Centro Antiveleni di Napoli Via A. Cardarelli, 9 +39 081 54 53 333
Az. Osp. "A. Cardarelli" 80131

Italy Centro Antiveleni di Verona Piazzale Aristide Stefani, 1 +39 800 011 858
Azienda Ospedaliera Integrata Verona 37126

SECTION 2: Hazards identification

2.1. Classification of the substance or mixture

Classification according to Regulation (EC) No. 1272/2008 [CLP]
Flammable Liquids, Category 2 H225
Severe eye injury/eye irritation, category 2 H319
Specific Target Organ Toxicity - Single Exposure, Category 3 - H336
Narcosis
Full text of H and EUH indications: see section 16

Adverse physicochemical, human health and environmental effects

Highly flammable liquid and vapours. May cause drowsiness or dizziness. Causes severe eye irritation.

2.2. Label elements

Labelling according to Regulation (EC) No. 1272/2008 [CLP]
Hazard pictograms (CLP) :

GHS02 GHS07
Warning (CLP) : Danger
Contains : propan-2-ol
Indications of danger (CLP) : H225 - Highly flammable liquids and vapours.
H319 - Causes severe eye irritation.
H336 - It may cause drowsiness or dizziness..
Cautionary Advice (CLP) : P210 - Keep away from heat, hot surfaces, sparks, open flames or other sources of ignition.
Do not smoke.
P261 - Avoid breathing mist, vapours.
P264 - Wash hands thoroughly after use.
P280 - Wear protective clothing. Protect eyes, face.P312 - In caso di malessere, contattare
un medico.
P403+P233 - Keep the container tightly closed and in a well-ventilated place.

2.3. Other hazards

This substance/mixture does not meet the PBT criteria of the REACH Regulation, Annex XIII
This substance/mixture does not meet the vPvB criteria of the REACH Regulation, Annex XIII
Contains no PBT and/or vPvB substances ≥ 0.1% evaluated in accordance with Annex XIII of REACH

The mixture does not contain a substance(s) included in the list established in accordance with Article 59(1) of REACH for possessing endocrine
disrupting properties, or is not identified as having endocrine disrupting properties in accordance with the criteria laid down in Commission
Delegated Regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 in concentrations equal to or greater than 0,1 %.

SECTION 3: Composition/information on ingredients

3.1. Substances
Not applicable

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Safety Data Sheet SDS n°81
according to Regulation (EC) No. 1907/2006 (REACH) with its amendment Regulation (EU) 2020/878
Revision 05 - Revision date: 08/02/2024 – CC22-109

3.2. Mixtures

Name Product identifier Conc. % w/w Classification according to Regulation (EC)

No. 1272/2008 [CLP]
Propan-2-ol CAS Number: 67-63-0 40 – 80 Flam. Liq. 2, H225
CE Number: 200-661-7 Eye Irrit. 2, H319
EU index number: 603-117-00-0 STOT SE 3, H336

Sodium dodecyl sulphate CAS Number: 151-21-3 <1 Flam. Sol. 1, H228
CE Number: 205-788-1 Acute Tox. 4 (orally), H302 (ATE=500 mg/kg of
body weight)
Acute Tox. 4 (by inhalation: dust, mist), H332
(ATE=1,5 mg/l/4h)
Skin Irrit. 2, H315
Eye Dam. 1, H318
STOT SE 3, H335
Aquatic Chronic 3, H412
Full text of H- and EUH-statements: see section 16

SECTION 4 : First aid measures

4.1. Description of first aid measures

General First-aid measures : If you feel unwell, contact a poison control centre or doctor.
First-aid measures after inhalation : Remove person to fresh air and keep comfortable for breathing.
First-aid measures after skin contact : Wash skin with plenty of water. Remove contaminated clothing. In case of skin irritation:
consult a doctor.
First-aid measures after eye contact : Rinse thoroughly for several minutes. Remove any contact lenses if it is easy to do so.
Continue rinsing. Call a doctor immediately.
First-aid measures after ingestion : If you feel unwell, contact a poison control centre or doctor

4.2. Most important symptoms and effects, both acute and delayed
Symptoms/effects : It may cause drowsiness or dizziness.
Symptoms/effects of inhalation : Although no precise data are known regarding the health effects on humans and animals,
inhalation of this material is considered to present a risk.
Symptoms/effects in the event of skin contact None under normal conditions
Symptoms/effects in case of eye contact Eye irritation
Symptoms/effects if swallowed None under normal conditions.

4.3. Indication of any immediate medical attention and special treatment needed
Treat symptomatically.

SECTION 5: Firefighting measures

5.1. Extinguishing media

Suitable extinguishing media : Water spray. Dry powder. Foam. Carbon dioxide.
Unsuitable extinguishing media : Do not use a compact jet of water.

5.2. Special hazards arising from the substance or mixture

Fire hazard : Highly flammable liquids and vapours
Danger of explosion No direct risk of explosion
Hazardous combustion products in case of fire Possible development of toxic fumes

5.3. Advice for firefighters

Extinction Instructions : Extinguish the fire from a safe distance/protected point. Do not enter the fire area without
the appropriate protective equipment, including self-contained breathing apparatus.

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Safety Data Sheet SDS n°81
according to Regulation (EC) No. 1907/2006 (REACH) with its amendment Regulation (EU) 2020/878
Revision 05 - Revision date: 08/02/2024 – CC22-109

Protection during firefighting : Do not act without appropriate protective equipment. Self-contained breathing apparatus.
Full body protection

SECTION 6: Accidental release measures

6.1. Personal precautions, protective equipment and emergency procedures

General measures Stop the leak if there is no danger. Inform the authorities if the product enters the sewage
system or public waters. Absorb the spillage to avoid material damage.

6.1.1. For non-emergency personnel

Protective equipment : Wear the recommended personal protective equipment.
Emergency procedures : Ventilate the spill area. No open flames, no sparks and no smoking. Avoid breathing
dust/fume/gas/mist/vapours/spray. Avoid contact with eyes and skin.

6.1.2. For emergency responders

Protective equipment : Do not act without appropriate protective equipment. For more information, see section 8:
'Exposure control-personal protection'.
Emergency procedures Remove unnecessary personnel. Stop the leak if there is no danger.

6.2. Environmental precautions

Avoid release to the environment.

6.3. Methods and material for containment and cleaning up

Methods for containment : Collect spilled material. Retain any spills with dikes or absorbents to prevent leakage or
penetration into sewers or watercourses. Stop spillage if possible without risk.
Methods for cleaning up : Absorb spilled liquid with absorbent material. Inform the authorities if the product enters the
sewage system or public waters.
Other information : Dispose of materials or solid residues at an authorized site.

6.4. Reference to other sections

See section 7 for information on self handling. See section 8 for information on personal protective equipment. See section 13 for information on
disposal.

SECTION 7: Handling and storage

7.1. Precautions for safe handling

Additional hazards in processing : It is not expected to present a significant risk under expected conditions of normal use.
Precautions for safe handling : Keep away from heat, hot surfaces, sparks, open flames or other sources of ignition. Do not
smoke. Ground/ground the container and the receiving device. Use only non-sparking tools.
Take precautions against electrostatic discharge. Flammable vapours may collect in the
container. Use explosion-proof equipment. Wear personal protective equipment. Use only
outdoors or in a well-ventilated place. Avoid breathing dust/fume/gas/mist/vapours/spray.
Avoid contact with eyes and skin.
Hygiene measures : Do not eat, drink or smoke when using this product. Always wash hands after handling the
product.

7.2. Conditions for safe storage, including any incompatibilities

Technical measures : Ground the container and the receiving device.
Storage Conditions : Store in a well-ventilated place. Store in a cool place. Keep container tightly closed. Store
under lock and key.
Packaging materials : Always store the product in a container of the same type as the original one.

7.3. Specific end use(s)

Wash buffer 1 is intended for in vitro diagnostic use. Use the product in accordance with the Good Laboratory Practice.

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Safety Data Sheet SDS n°81
according to Regulation (EC) No. 1907/2006 (REACH) with its amendment Regulation (EU) 2020/878
Revision 05 - Revision date: 08/02/2024 – CC22-109

SECTION 8: Exposure controls/personal protection

8.1. Control parameters

8.1.1 National occupational exposure and biological limit values

Propan-2-ol (67-63-0)
Czech Republic - Occupational Exposure Limit Values

Local name 2-Propanol (Isopropanol; Isopropylalkohol)

PEL (OEL TWA) 500 mg/m³

PEL (OEL TWA) [ppm] 200 ppm

NPK-P (OEL C) 1000 mg/m³

NPK-P (OEL C) [ppm] 400 ppm

Comment I - dráždí sliznice (oči, dýchací cesty) resp. kůži.

Normative reference Nařízení vlády č. 361/2007 Sb. (Předpis 330/2023 Sb.)

Denmark - Occupational Exposure Limit Values

Local name Isopropylalkohol (Isopropanol; 2-Propanol; sec-Propylalkohol)

OEL TWA [1] 490 mg/m³

OEL TWA [2] 200 ppm

Normative reference BEK nr 202 af 21/02/2023

Finland - Occupational Exposure Limit Values

Local name 2-Propanoli

HTP (OEL TWA) [1] 500 mg/m³

HTP (OEL TWA) [2] 200 ppm

HTP (OEL STEL) 620 mg/m³

HTP (OEL STEL) [ppm] 250 ppm

Normative reference HTP-ARVOT 2020 (Sosiaali- ja terveysministeriö)

France - Occupational Exposure Limit Values

Local name Alcool isopropylique

VLE (OEL C/STEL) 980 mg/m³

VLE (OEL C/STEL) [ppm] 400 ppm

Comment Valeurs recommandées/admises

Normative reference Circulaire du Ministère du travail (réf.: INRS ED 6443, 2022; Outil65)

Germany - Occupational Exposure Limit Values (TRGS 900)

Local name Propan-2-ol

AGW (OEL TWA) [1] 500 mg/m³

AGW (OEL TWA) [2] 200 ppm

Peak exposure limitation factor 2(II)

Comment DFG - Senatskommission zur Prüfung gesundheitsschädlicher Arbeitsstoffe der DFG

(MAK-Kommission); Y - Ein Risiko der Fruchtschädigung braucht bei Einhaltung des
Arbeitsplatzgrenzwertes und des biologischen Grenzwertes (BGW) nicht befürchtet zu
werden

Normative reference TRGS900

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according to Regulation (EC) No. 1907/2006 (REACH) with its amendment Regulation (EU) 2020/878
Revision 05 - Revision date: 08/02/2024 – CC22-109

Propan-2-ol (67-63-0)
Germany - Biological limit values (TRGS 903)

Local name Propan-2-ol

Biological limit value 25 mg/l Parameter: Aceton - Untersuchungsmaterial: B = Vollblut, U = Urin -

Probenahmezeitpunkt: b) Expositionsende, bzw. Schichtende - Festlegung/Begründung:
11/2012 DFG
25 mg/l Parameter: Aceton - Untersuchungsmaterial: U = Urin - Probenahmezeitpunkt: b)
Expositionsende, bzw. Schichtende - Festlegung/Begründung: 11/2012 DFG

Normative reference TRGS 903

Greece - Occupational Exposure Limit Values

Local name Ισοπροπυλική αλκοόλη

OEL TWA 980 mg/m³

400 ppm

OEL STEL 1225 mg/m³

500 ppm

Normative reference Π.Δ. 90/1999 - Προστασία της υγείας των εργαζομένων που εκτίθενται σε ορισμένους
χημικούς παράγοντες κατά τη διάρκεια της εργασίας τους

Hungary - Occupational Exposure Limit Values

Local name IZOPROPIL-ALKOHOL

AK (OEL TWA) 500 mg/m³

CK (OEL STEL) 1000 mg/m³

Comment b (Bőrön át is felszívódik), i (ingerlő anyag, amely izgatja a bőrt, nyálkahártyát, szemet
vagy mindhármat); R (Azok az anyagok, amelyek egészségkárosító hatása RÖVID
expozíció hatására jelentkezik)

Normative reference 5/2020. (II. 6.) ITM rendelet - A kémiai kóroki tényezők hatásának kitett munkavállalók
egészségének és biztonságának védelméről

Hungary - Biological Indices of Exposure

Local name Izopropil-alkohol (2-Propanol)

BEI 25 mg/l Biológiai expozíciós (hatás) mutató: aceton - Biológiai minta: vizeletben -
Mintavétel ideje: m.v. (műszak végén)
430 µmol/L Biológiai expozíciós (hatás) mutató: aceton - Biológiai minta: vizeletben -
Mintavétel ideje: m.v. (műszak végén)

Comment A foglalkozási vegyi expozíció esetén ajánlott biológiai expozíciós és hatásmutatók

határértékei

Normative reference 5/2020. (II. 6.) ITM rendelet - A kémiai kóroki tényezők hatásának kitett munkavállalók
egészségének és biztonságának védelméről

Lithuania - Occupational Exposure Limit Values

Local name 2-propanolis (izopropanolis, izopropilo alkoholis)

IPRV (OEL TWA) 350 mg/m³

IPRV (OEL TWA) [ppm] 150 ppm

TPRV (OEL STEL) 600 mg/m³

TPRV (OEL STEL) [ppm] 250 ppm

Normative reference LIETUVOS HIGIENOS NORMA HN 23:2011 (Nr. V-695/A1-272, 2018-06-12)

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Propan-2-ol (67-63-0)
Poland - Occupational Exposure Limit Values

Local name Propan-2-ol (izopropylowy alkohol)

NDS (OEL TWA) 900 mg/m³

NDSCh (OEL STEL) 1200 mg/m³

Comment Skóra (Oznakowanie substancji notacją „skóra” oznacza, że wchłanianie substancji przez
skórę może być tak samo istotne jak przy narażeniu drogą oddechową).

Normative reference Dz. U. 2018 poz. 1286 wraz z późn. zm.

Portugal - Occupational Exposure Limit Values

Local name 2-Propanol (isopropanol ou álcool isopropílico)

OEL TWA 200 ppm

OEL STEL 400 ppm

Comment A4 (Agente não classificável como carcinogénico no Homem); IBE (Índice biológico de
exposição)

Normative reference Norma Portuguesa NP 1796:2014

Portugal - Biological Indices of Exposure

Local name 2-Propanol

BEI 40 mg/l Parâmetro: Acetona - Meio: urina - Momento da amostragem: Fim do turno no fim
da semana de trabalho - Notaçao: Vb (Valor basal), Ne (Não específico)

Normative reference Norma Portuguesa NP 1796:2014

Romania - Occupational Exposure Limit Values

Local name Alcool izopropilic/2-Propanol

OEL TWA 200 mg/m³

81 ppm

OEL STEL 500 mg/m³

203 ppm

Normative reference Hotărârea Guvernului nr. 1.218/2006 (Hotărârea nr. 53/2021)

Romania - Biological Limit Values

Local name Alcool izopropilic

BLV 50 mg/l Indicador biologic: Acetonă - Material biologic: urină - Momentul recoltarii: sfârşit
de schimb

Normative reference Hotărârea Guvernului nr. 1.218/2006 (Hotărârea nr. 584/2018)

Slovakia - Occupational Exposure Limit Values

Local name Izopropylalkohol (propán-2-ol)

NPHV (OEL TWA) [1] 500 mg/m³

NPHV (OEL TWA) [2] 200 ppm

NPHV (OEL STEL) 1000 mg/m³

NPHV (OEL STEL) [ppm] 400 ppm

Normative reference Nariadenie vlády č. 355/2006 Z. z. (236/2020 Z. z.)

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Propan-2-ol (67-63-0)
Slovenia - Occupational Exposure Limit Values

Local name propan-2-ol (izopropilalkohol; izopropanol)

OEL TWA 500 mg/m³

200 ppm

OEL STEL 1000 mg/m³

400 ppm

Comment Y (Snovi, pri katerih ni nevarnosti za zarodek ob upoštevanju mejnih vrednosti in bat
vrednosti), BAT (Biološka mejna vrednost)

Normative reference Uradni list RS, št. 72/2021 z dne 11.5.2021

Slovenia - Biological Limit Values

Local name 2‐propanol

BLV 25 mg/l Parameter: aceton - Biološki vzorec: kri - Čas vzorčenja: ob koncu delovne
izmene
25 mg/l Parameter: aceton - Biološki vzorec: urin - Čas vzorčenja: ob koncu delovne
izmene

Normative reference Uradni list RS, št. 72/2021 z dne 11.5.2021

Spain - Occupational Exposure Limit Values

Local name Isopropanol (Alcohol isopropílico)

VLA-ED (OEL TWA) [1] 500 mg/m³

VLA-ED (OEL TWA) [2] 200 ppm

VLA-EC (OEL STEL) 1000 mg/m³

VLA-EC (OEL STEL) [ppm] 400 ppm

Comment VLB® (Agente químico que tiene Valor Límite Biológico), s (Esta sustancia tiene prohibida
total o parcialmente su comercialización y uso como fitosanitario y/o como biocida. Para
una información detallada acerca de las prohibiciones consúltese: Base de datos de
productos biocidas: http://www.msssi.gob.es/ciudadanos/productos.do?tipo=plaguicidas
Base de datos de productos fitosanitarios
http://www.magrama.gob.es/agricultura/pags/fitos/registro/fichas/pdf/Lista_sa.pdf).

Normative reference Límites de Exposición Profesional para Agentes Químicos en España 2023. INSHT

Spain - Biological limit values

Local name Isopropanol (Alcohol isopropílico)

BLV 40 mg/l Parámetro: Acetona - Medio: Orina - Momento de muestreo: Final de la semana
laboral - Notas: F (Fondo. El indicador está generalmente presente en cantidades
detectables en personas no expuestas laboraboralmente. Estos niveles de fondo están
considerados en el valor VLB), I (Significa que el indicador biológico es inespecífico
puesto que puede encontrarse después de la exposición a otros agentes químicos)

Normative reference Límites de Exposición Profesional para Agentes Químicos en España 2023. INSHT

USA - ACGIH - Occupational Exposure Limit Values

Local name 2-Propanol

ACGIH OEL TWA [ppm] 200 ppm

ACGIH OEL STEL 400 ppm

Comment (ACGIH) TLV® Basis: Eye & URT irr; CNS impair. Notations: A4 (Not classifiable as a Human
Carcinogen); BEI

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Propan-2-ol (67-63-0)
Normative reference ACGIH 2024

USA - ACGIH - Biological Indices of Exposure

Local name 2-Propanol

BEI 40 mg/l Parameter: Acetone - Medium: urine - Sampling time: End of shift at end of
workweek - Notations: B, Ns

Normative reference ACGIH 2024

8.1.2. Recommended monitoring procedures

Monitoring Methods
Monitoring Methods The measurement of substances in the working environment must be carried out by
standardised methods or, in their absence, by appropriate methods.

8.1.3. Air contaminants formed

No additional information available

8.1.4. DNEL and PNEC

Sodium dodecyl sulphate (151-21-3)

DNEL/DMEL (Workers)

Long-term - systemic effects, skin 4060 mg/kg of body weight/day

Long-term - systemic effects, inhalation 285 mg/m³

DNEL/DMEL (General population)

Long-term - systemic effects,oral 24 mg/kg of body weight/day

Long-term - systemic effects, inhalation 85 mg/m³

Long-term - systemic effects, skin 2440 mg/kg of body weight/day

PNEC (Water)

PNEC water (fresh water) 0,176 mg/l

PNEC water (seawater) 0,0176 mg/l

PNEC water (intermittent, fresh water) 0,055 mg/l

PNEC (Sediment)

PNEC sediment (fresh water) 6,97 mg/kg dry weight

PNEC sediment (seawater) 0,697 mg/kg dry weight

PNEC (Soil)

PNEC soil 1,29 mg/kg dry weight

PNEC (STP)

PNEC Waste water treatment plant 1,35 mg/l

Propan-2-ol (67-63-0)
DNEL/DMEL (Workers)

Acute - systemic effects, inhalation 1000 mg/m³

Long-term - systemic effects, skin 888 mg/kg of body weight/day

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according to Regulation (EC) No. 1907/2006 (REACH) with its amendment Regulation (EU) 2020/878
Revision 05 - Revision date: 08/02/2024 – CC22-109

Propan-2-ol (67-63-0)
Long-term - systemic effects, inhalation 500 mg/m³

DNEL/DMEL (General population)

Acute - systemic effects, inhalation 178 mg/m³

Acute - systemic effects, oral 51 mg/kg of body weight/day

Long-term - systemic effects,oral 26 mg/kg of body weight/day

Long-term - systemic effects, inhalation 89 mg/m³

Long-term - systemic effects, skin 319 mg/kg of body weight/day

8.1.5. Control banding

No additional information available

8.2. Exposure controls

8.2.1. Appropriate engineering controls
Suitable technical controls:
Ensure good ventilation of the workplace.

8.2.2. Personal protection equipment

Personal protective equipment:
Wear recommended personal protective equipment.
Personal Protective Equipment Symbol(s):

8.2.2.1. Eye and face protection

Eye protection:
Safety glasses.

8.2.2.2. Skin protection

Skin and body protection:
Use suitable protective clothing.

Hand protection:
Wear protective gloves.

8.2.2.3. Respiratory protection

Respiratory protection:
In case of insufficient ventilation, use a suitable respiratory device.

8.2.2.4. Thermal hazards

No additional information available

8.2.3. Environmental exposure controls

Environmental exposure controls:
Avoid release to the environment.
Other information:
Appropriate technical exposure control measures, to be taken in the workplace, must be selected and applied following the risk assessment carried
out by the employer, in relation to his work activity (in accordance with Directive 98/24/EEC, implemented by Legislative Decree 81 of 9 April 2008
as amended and supplemented).

Revision 05 EN (English) 10/19

Revision date: 08/02/2024 SDS 81
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Safety Data Sheet SDS n°81
according to Regulation (EC) No. 1907/2006 (REACH) with its amendment Regulation (EU) 2020/878
Revision 05 - Revision date: 08/02/2024 – CC22-109

SECTION 9: Physical and chemical properties

9.1. Information on basic physical and chemical properties

Physical state : Liquid
Colour : Not available
Odour : Not available.
Odour threshold : Not available
Melting point : Not applicable
Freezing point : Not available
Boiling point : Not available
Flammability : Highly flammable liquids and vapours
Explosive properties : Not available
Oxidising properties : Not available
Lower explosion limit : Not available
Upper explosion limit : Not available
Flash point : Not available
Auto-ignition temperature : Not available
Decomposition temperature : Not available
pH : Not available
Viscosity, kinematic : Not available
Solubility : Not available
Partition coefficient n-octanol/water (Log Kow) : Not available
Vapour pressure : Not available
Vapour pressure at 50°C : Not available
Density : Not available
Relative density : Not available
Relative vapour density at 20°C : Not available
Particle characteristics : Not applicable

9.2. Other information

9.2.1. Information with regard to physical hazard classes
No additional information available

9.2.2. Other safety characteristics

No additional information available

SECTION 10: Stability and reactivity

10.1. Reactivity
Highly flammable liquids and vapours.

10.2. Chemical stability

Stable under normal conditions.

10.3. Possibility of hazardous reactions

No knowledge of dangerous reactions under normal conditions of use.

10.4. Conditions to avoid

Avoid contact with hot surfaces. Heat. No flames, no sparks. Eliminate all sources of ignition.

10.5. Incompatible materials

No further information available.

10.6. Hazardous decomposition products

Under normal conditions of storage and use, no hazardous decomposition products should be created.

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SECTION 11: Toxicological information

11.1. Information on hazard classes as defined in Regulation (EC) No 1272/2008

Acute toxicity (oral) : Not classified (Based on available data, the classification criteria are not met)
Acute toxicity (dermal) : Not classified (Based on available data, the classification criteria are not met)
Acute toxicity (inhalation) : Not classified (Based on available data, the classification criteria are not met)

Sodium dodecyl sulphate (151-21-3)

DL50 cutaneous rat > 2000 mg/kg of body weight OECD Guideline 402

STA CLP (oral) 500 mg/kg of body weight

STA CLP (dusts,mists) 1,5 mg/l/4h

Skin corrosion/irritation : Not classified (Based on available data, the classification criteria are not met)

Sodium dodecyl sulphate (151-21-3)

pH 9,1

Serious eye damage/irritation : Causes severe eye irritation.

Sodium dodecyl sulphate (151-21-3)

pH 9,1

Respiratory or skin sensitisation : Not classified (Based on available data, the classification criteria are not met)
Germ cell mutagenicity : Not classified (Based on available data, the classification criteria are not met)
Carcinogenicity : Not classified (Based on available data, the classification criteria are not met)
Reproductive toxicity : Not classified (Based on available data, the classification criteria are not met)
STOT-single exposure : May cause drowsiness or dizziness Not classi

Sodium dodecyl sulphate (151-21-3)

STOT-single exposure May irritate the respiratory tract

Propan-2-ol (67-63-0)
STOT-single exposure May cause drowsiness or dizziness
STOT-repeated exposure : Not classified (No danger is expected in the event of aspiration, given the physical form and
professional use of the product).

Aspiration hazard : Not classified (No danger is expected in the event of aspiration, given the physical form and
professional use of the product).

11.2. Information on other hazards

11.2.1. Endocrine disrupting properties
Adverse health effects caused by endocrine : The mixture does not contain a substance(s) included in the list established in accordance
disrupting properties with Article 59(1) of REACH for possessing endocrine disrupting properties, or is not
identified as having endocrine disrupting properties in accordance with the criteria laid down
in Commission Delegated Regulation (EU) 2017/2100 or Commission Regulation (EU)
2018/605

11.2.2. Other information

No further information available

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SECTION 12: Ecological information

12.1. Toxicity
Ecology - general : The product is not considered hazardous to aquatic organisms and does not cause any
long-term undesirable effects on the environment.
Hazardous to the aquatic environment, short–term : Not classified (Based on available data, the classification criteria are not met)
(acute)
Hazardous to the aquatic environment, long–term : Not classified (Based on available data, the classification criteria are not met)
(chronic)
Sodium dodecyl sulphate (151-21-3)
CL50 - Fish [1] 29 mg/l Pimephales promelas

CE50 - Other aquatic organisms [1] 11,1 mg/l

CE50 72h - Algae [1] > 120 mg/l Desmodesmus subspicatus

CE50 72h - Algae [2] 53 mg/l Desmodesmus subspicatus

NOEC chronic fish ≥ 1,357 mg/l Pimephales promelas

Propan-2-ol (67-63-0)
CL50 - Fish [1] 10000 mg/l Pimephales promelas

CL50 - Fish [2] 9640 mg/l Pimephales promelas

12.2. Persistence and degradability

Sodium dodecyl sulphate (151-21-3)

Persistence and degradability Not rapidly degradable

Propan-2-ol (67-63-0)
Persistence and degradability Not rapidly degradable

12.3. Bioaccumulative potential

No further information available.

12.4. Mobility in soil

No further information available.

12.5. Results of PBT and vPvB assessment

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This substance/mixture does not meet the PBT criteria of the REACH Regulation, Annex XIII

This substance/mixture does not meet the vPvB criteria of the REACH Regulation, Annex XIII

12.6. Endocrine disrupting properties

Adverse effects on the environment caused by : The mixture does not contain a substance(s) included in the list established in accordance
endocrine disrupting properties with Article 59(1) of REACH for possessing endocrine disrupting properties, or is not
identified as having endocrine disrupting properties according to the criteria laid down in
Commission Delegated Regulation (EU) 2017/2100 or Commission Regulation (EU)
2018/605.

12.7. Other adverse effects

No further information available.

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SECTION 13: Disposal considerations

13.1. Waste treatment methods

Regional waste regulation Disposal in accordance with legal requirements.
Waste treatment methods : Dispose of the contents/container in accordance with the sorting instructions of the
authorised collector.
Sewerage Recommendations Disposal in accordance with legal requirements.
Advice on Disposal of Product/Packaging Disposal in accordance with legal requirements.
Further indications Flammable vapours may collect in the container. Do not reuse empty containers.

SECTION 14: Transport information

In accordance with ADR / IMDG / IATA / RID
ADR IMDG IATA RID

14.1. UN number or ID number

UN 1219 UN 1219 UN 1219 UN 1219

14.2. UN proper shipping name

ISOPROPANOLO (ALCOL ISOPROPANOL (ISOPROPYL Isopropanol ISOPROPANOLO (ALCOL
ISOPROPILICO) ALCOHOL) ISOPROPILICO)

Description of transport document

UN 1219 ISOPROPANOLO UN 1219 ISOPROPANOL UN 1219 Isopropanol, 3, II UN 1219 ISOPROPANOLO

(ALCOL ISOPROPILICO), 3, II, (ISOPROPYL ALCOHOL), 3, II (ALCOL ISOPROPILICO), 3, II
(D/E) (12°C c.c.)

14.3. Transport hazard class(es)

3 3 3 3

14.4. Packing group

II II II II

14.5. Environmental hazards

Dangerous for the environment: No Dangerous for the environment: No Dangerous for the environment: No Dangerous for the environment: No
Marine pollutant: No

No supplementary information available

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14.6. Special precautions for user

Overland transport
Classification code (ADR) : F1
Special Provisions (ADR) : 274, 601, 640C
Limited quantities (ADR) : 1l
Exempt quantities (ADR) : E2
Packaging Instructions (ADR) : P001
Special Packaging Provisions (ADR) : MP19
Provisions Concerning Joint Packaging (RID) : F1
Transport instructions in mobile tanks and bulk : T7
containers (ADR)
Special Provisions for Mobile Tanks and Bulk : TP1, TP8, TP28
Containers (ADR)
Tank code (ADR) : L1.5BN
Tanker transport vehicle : FL
Transport category (ADR) : 2
Special Transport Provisions - Operation (ADR) : S2, S20
Hazard Identification Number (n°. Kemler) : 33
Orange panel :

Codice restrizione in galleria (ADR) : D/E

Codice EAC : •3YE

Transport by sea
Special Provisions (IMDG) :274
Limited quantities (IMDG) :1 L
Exempt quantities (IMDG) :E2
Packaging Instructions (IMDG) :P001
Special Provisions for Packaging (IMDG) :IBC02
Packaging Instructions IBC (IMDG) :T7
Tank instructions (IMDG) :TP1, TP28, TP8
Special tank provisions (IMDG) :F-E
N° EmS (Incendio) :S-E
N° EmS (Fuoriuscita) :B
Stowage category (IMDG) :274

Air transport
Quantity exempt passenger and cargo aircraft (IATA) :E2
Limited quantities passenger and cargo aircraft (IATA) :Y341
Maximum net quantities of limited passenger and cargo :1L
aircraft (IATA)
Air Passenger and Cargo Packing Instructions (IATA) :353
Maximum net quantities per passenger and cargo :5L
aircraft (IATA)
Air Cargo Packing Instructions (IATA) :364
Maximum net quantity cargo aircraft (IATA) :60L
Special Provisions (IATA) :A3
Code ERG (IATA) :3H

Rail transport
Classification code (RID) F1
Special Provisions (RID) 274, 601, 640C
Quantità limitate (RID) 1L
Exempt quantities (RID) E2
Packaging Instructions (RID) P001
Provisions Concerning Joint Packaging (RID) MP19
Transport instructions in mobile tanks and bulk containers (RID) T7
Special Provisions for Mobile Tanks and Bulk Containers (RID) TP1, TP8, TP28

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Tank codes (RID) L1.5BN

Transport category (RID) 2
Express parcels (RID) CE7
Hazard identification number (RID) 33

14.7. Maritime transport in bulk according to IMO instruments

Not applicable

SECTION 15: Regulatory information

15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture
15.1.1. EU-Regulations
Other information, restriction and prohibition : Commission Directive 2000/39/EC of 8 June 2000 establishing a first list of indicative limit
regulations values in implementation of Council Directive 98/24/EC on the protection of workers from
the risks related to chemical agents at work. Council Directive 89/391/EEC of 12 June 1989
on the introduction of measures to encourage improvements in the safety and health of
workers at work and subsequent national transpositions. REGULATION (EU) 2016/425 OF
THE EUROPEAN PARLIAMENT AND OF THE COUNCIL of 9 March 2016 on personal
protective equipment and repealing Council Directive 89/686/EEC.

REACH Annex XVII (Restriction List)

Contains no substance(s) listed on REACH Annex XVII (Restriction Conditions)

REACH Annex XIV (Authorisation List)

Contains no substance(s) listed on Annex XIV of REACH (Authorisation List).

REACH Candidate List (SVHC)

Contains no substance(s) listed on REACH candidate list.

PIC Regulation (Prior Informed Consent)

Contains no substance(s) listed on the PIC list (Regulation EU 649/2012 concerning the export and import of hazardous chemicals)

POP Regulation (Persistent Organic Pollutants)

Contains no substance(s) listed on the POP list (Regulation EU 2019/1021 on persistent organic pollutants)

Ozone Regulation (1005/2009)

Contains no substance(s) listed on the Ozone Depletion list (Regulation EU 1005/2009 on substances that deplete the ozone layer)

Dual-Use Regulation (428/2009)

Contains no substance(s) subject to COUNCIL REGULATION (EC) No 428/2009 of 5 May 2009 setting up a Community regime for the control of
exports, transfer, brokering and transit of dual-use items.

Explosives Precursors Regulation (2019/1148)

Contains no substance(s) listed on the Explosives Precursors list (Regulation EU 2019/1148 on the marketing and use of explosives precursors)

Drug Precursors Regulation (273/2004)

Contains no substance(s) listed on the Drug Precursors list (Regulation EC 273/2004 on the manufacture and the placing on market of certain
substances used in the illicit manufacture of narcotic drugs and psychotropic substances)

15.1.2. National regulations

No further information available

15.2. Chemical safety assessment

No chemical safety assessment has been carried out

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SECTION 16: Other information

Indication of changes:

Issue date: 08/06/2015

Revision 01, 30/05/2016: CC15-16.
Revision 02, 31/05/2018: CC18-15.
Revision 03, 09/11/2018 - CC18-45.
Revision 04, 19/02/2021 – SCP2019-023
Revision 05: 08/02/2024, CC22-109: update of sections 1-16, according to Regulation 2020/878.

Abbreviations and acronyms:

ACGIH American Conference of Governmental Industrial Hygienists

ADN European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways

ADR European Agreement concerning the International Carriage of Dangerous Goods by Road

BCF Bioconcentration factor

BEI Biological Esposure Indices

BLV Biological limit value

CAS Chemical Abstract Service (division of the American Chemical Society)

EC50 Median effective concentration

LC50 Median lethal concentration

CLP Classification Labelling Packaging Regulation; Regulation (EC) No 1272/2008

LD50 Median lethal dose

DMEL Derived Minimal Effect level

DNEL Derived-No Effect Level

ED Endocrine disrupting properties

EINECS European Inventory of Existing Commercial Substances

EPA US Environmental Protection Agency

IATA International Air Transport Association

IMDG International Maritime Dangerous Goods

LOAEL Lowest Observed Adverse Effect Level

NOAEC No-Observed Adverse Effect Concentration

NOAEL No-Observed Adverse Effect Level

NOEC No-Observed Effect Concentration

NTP National Toxicology Program

OECD Organisation for Economic Co-operation and Development

OEL Occupational Exposure Limit

OSHA Occupational Safety and Health Administration

PBT Persistent Bioaccumulative Toxic

PNEC Predicted No-Effect Concentration

PPE Personal protective Equipment

REACH Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation (EC) No 1907/2006

RID Regulations concerning the International Carriage of Dangerous Goods by Rail

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Abbreviations and acronyms:

SDS Safety Data Sheet

ATE Acute Toxicity Estimate

STP Sewage treatment plant

TLV/TWA Threshold Limit Value/Threshold Weighted Average

vPvB Very Persistent and Very Bioaccumulative

SVHC: substance of very high concern

SVHC: substance of very high concern

Data sources : ECHA database

Training advice : Adequately train workers potentially exposed to this substance on the basis of the contents
of this safety data sheet. The training of workers must include contents, updates and
duration according to the risk profiles assigned to the working sectors to which they belong,
according to the procedures provided for by Legislative Decree 81/2008.
Full text of hazard statements H and EUH:
Acute Tox. 4 (inhalation) Acute toxicity (inhalation), category 4

Acute Tox. 4 (oral) Acute toxicity (oral), category 4

Aquatic Acute 1 Dangerous for the aquatic environment - Acute danger, category 1

Aquatic Chronic 1 Hazardous to the Aquatic Environment - Chronic Hazard, Category 1

Eye Dam. 1 Severe eye injury/eye irritation, category 1

H302 Harmful if swallowed.

H312 Harmful in contact with skin.

H315 Causes skin irritation.

H318 Causes serious eye injuries.

H319 Causes severe eye irritation.

H410 Very toxic to aquatic organisms with long-lasting effects.

H411 Toxic to aquatic organisms with long-lasting effects.

Skin Irrit. 2 Skin corrosion/irritation, category 2

Classification and procedures used to determine the classification of mixtures under Regulation (EC) 1272/2008 [CLP]:
Acute Tox. 4 (per via H302 Calculation method
orale)

Skin Irrit. 2 H315 Calculation method

Eye Dam. 1 H318 Calculation method

Aquatic Chronic 2 H411 Calculation method

Safety Data Sheet (SDS), EU

This document is intended to provide guidance for the appropriate and precautionary handling of this product by qualified personnel or under the
supervision of personnel experienced in handling chemicals. The product should not be used for purposes other than those indicated in section 1
unless adequate written information on how to handle the material has been received. The person responsible for this document cannot give
warnings about all hazards arising from use or interaction with other chemicals or materials. It is the responsibility of the user to ensure the safe use
of the product, the suitability of the product for the use for which it is applied and the proper disposal. The information below is not intended to be a
representation or warranty, either expressed or implied, of merchantability, fitness for a particular purpose, quality, or any other nature. The
information contained in this SDS complies with Regulation (EU) 2020/878.

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