Splinting for Dental Trauma in Children
Splinting for Dental Trauma in Children
[Link]
SYSTEMATIC REVIEW
Abstract
Purpose The purpose of this study was to gather existing data on the efficacy of tooth splinting (TS) in patients with trau-
matized primary teeth, evaluating their overall prognosis and reported complications.
Methods Electronic searches were performed in seven databases up to Februray/2023. Clinical studies published in the last
two decades and presenting the following characteristics were included: (a) reporting on children with traumatized primary
teeth; (b) describing the efficacy of splinting those teeth. Studies describing imobilization of dental avulsion were excluded.
Results A total of 163 potentially relevant studies were initially found. After title/abstract screening, and full-text evaluation,
three retrospective studies with moderate to high risk of bias were included. The studies described the outcomes of TS in
primary teeth with luxation (intrusion, extrusion, lateral displacement), intra-alveolar root fracture, and/or alveolar fracture.
High clinical success rate was observed for teeth with root fracture. Benefits of spliting teeth with lateral luxation were not
identified, although it may be a reccomended approach. No study was found evaluating TS for alveolar fracture.
Conclusion Based on a low level of evidence, the findings highlight a better clinical success rate of the use of TS in the
management of deciduous teeth with root fractures.
Keywords Splinting · Dental trauma · Deciduous dentition · Primary tooth trauma · Children
13
Vol.:(0123456789)
European Archives of Paediatric Dentistry
use of flexible splint for a period of four weeks in cases of • P (Population): children with trauma to primary teeth;
radicular fracture, alveolar fracture, or lateral dislocation3, • I (Intervention): tooth splinting;
other clinical approaches for splinting primary teeth with • C (Comparator): no tooth splinting, if a comparator group
alveolar fracture are suggested in the literature, including was included;
orthodontic wire in several thicknesses (Akin et al. 2011; Liu • O (Outcome): clinical and radiographic parametres
et al. 2013), resin composite (Pathak et al. 2016; Song et al. (mobility, pulp necrosis, pathological root resorption,
2017), acrylic (Goswami and Eranhikkal 2020), wire with pathological loss of teeth, ankylosis, pathological bone
composite (Kahler et al. 2016; Kim et al. 2012; Shanmugam resorption, and resporption of fracturated root).
et al. 2011), and EVA (Ethylene–Vinyl Acetate copolymer)
vacuum-formed (Chatzidimitriou et al. 2017). The duration Eligibility: inclusion and exclusion criteria
of treatment also varies, ranging from two weeks (Shan-
mugam et al. 2011; Song et al. 2017) to three months (Bour- Clinical studies published within the last two decades (after
guignon et al. 2020; Day et al. 2020; Liu et al. 2013). The 2003), including children with trauma in primary dentition
wide variety of possible trauma scenarios and multiple treat- (luxation injuries, root fracture, and alveolar fracture) were
ment options make it challenging for practitioners to provide eligible. The included human studies comprised randomized
evidence-based treatment and recommend the best treatment controlled clinical trials, controlled clinical trials, retrospec-
option for the patient. As a result, many of the treatments for tive and prospective case–control studies, and case series
TDIs are far from ideal (Andreasen et al. 2012). studies with a minimum follow-up time of 6 months. The
In general, there is limited evidence to support many of IADT guidelines suggest that avulsed primary teeth should
the standard treatments in the primary dentition (Day et al. not be reimplanted after trauma and, therefore, the use of
2020). Traumatology research mostly comprises non-ran- splinting is not recommended in this type of TDIs. There-
domized clinical trials (Cho et al. 2018; Kim et al. 2012; fore, studies that considered the use of splinting in the treat-
Song et al. 2017), which represent lower quality evidence, in ment of avulsed teeth were excluded (Day et al. 2020).
comparison to randomized clinical trials (RCT) (Andreasen
et al. 2012). This is probably due to the ethical issues asso- Search strategy
ciated with getting informed consent from an injured child
to participate in an RCT (Andreasen et al. 2012). Obser- Seven electronic bibliographic databases were screened:
vational studies, however, can provide useful information MEDLINE (via PubMed), Web of Science, Scopus, Scielo,
about dental trauma management. Thus, the aim of this sys- Embase, EBSCO, and Cochrane Library. Search strategies
temtic review was to analyze the published evidence on the were developed for each database using a combination of
benefits of splinting traumatized primary teeth, including free terms and, whenever applicable, indexed terms specifi-
overall prognosis and reported complications. cally to each database. In an effort to identify other relevant
studies, the reference list of the studies included in this sys-
tematic review were further manually assessed, as well as all
issues published between 2013–2023 in major international
Methods
Dental journals (Journal of Dentistry, Dental Traumatology,
and International Journal of Paedriatric Dentistry). A search
This study protocol was registered at the International Pro-
for gray literature was also performed on Google Scholar
spective Register of Systematic Reviews (PROSPERO;
database using an adapted search strategy. Only the first
[Link] under approval code
200 studies were screened for eligibility on this database.
#CRD42021240885. This manuscript follows the Preferred
Initially, no restrictions of language or date of publication
Reporting Items for Systematic Reviews and Meta-Analy-
were applied. The last search was run on 23rd February,
ses (PRISMA) statement checklist (Page et al. 2021). The
2023. The full search strategy for each database is described
authors declare no potential conflict of interest with respect
in Appendix 1.
to the research, authorship, and/or publication of this study.
Results of literature searches were uploaded in the End-
note 20.1 program (Clarivate Analytics©, Thomson Reuters,
Review question New York, NY, USA), and duplicate records were removed.
Two researchers (MSF and ABGA) independently screened
The present study is based on the following review question: all titles and abstracts considering the abovementioned eli-
“Does splinting of traumatized primary teeth improve clini- gibility criteria. The same two researchers independently
cal outcomes?”. The PICO strategy was used to guide the assessed the full text of the included studies, and discrep-
construction of the research question and literature search ancies were solved by a third researcher (MLG). Regard-
(da Costa Santos et al. 2007), as presented below: ing study selection, kappa coefficients between the two
13
European Archives of Paediatric Dentistry
researchers were 0.95 and 0.97 for title/abstract and full-text which seven were excluded because they did not evaluate the
selection, respectively. efficacy of splinting in primary teeth and eight (Akin et al.
2011; Bonanato et al. 2009; Chatzidimitriou et al. 2017;
Data extraction and synthesis of evidence Di Giorgio et al. 2021; Liu et al. 2013; Pathak et al. 2016;
Santos et al. 2021; Shanmugam et al. 2011) because they
A data extraction sheet based on the Cochrane Consumers where case reports. Therefore, 3 retrospective studies (Cho
and Communication Review Group’s data extraction tem- et al. 2018; Kim et al. 2012; Song et al. 2017) were included
plate was adapted for this study. The following data were (Table 1). Figure 1 presents the flow chart of study inclusion
extracted: (a) author; (b) year; (c) country; (d) study design; process following the PRISMA statement recommendation.
(e) sample size; (f) age group and sex; (g) type of trauma; All studies included were conducted in Korea (Cho et al.
(h) milimeters of luxation; (i) diagnostic methods used in the 2018; Kim et al. 2012; Song et al. 2017). The treatment
first examination; (j) type of splinting; (k) protocol; (l) other success rate of the use of resin wire-split in the treatment
details; (m) control group; (n) period of time to seek treat- of children (n = 10) with the presence of intra-alveolar root
ment; (o) duration of treatment; (p) follow-up time; (q) diag- fracture (n = 16 teeth) after a mean follow-up period of
nostic methods used in the last/follow-up examination; (r) 23 months is described in the Kim et al. (2012) study (Kim
main results/effect measurements; and (s) main conclusions. et al. 2012). Song et al. (2017) presented the success rate of
A third reviewer (MLG) double checked all extracted data. treatment of teeth with lateral (n = 38) and intrusive (n = 14)
Due to the high heterogeneity among the methods of luxation using different splinting techniques after an average
the included studies, no meta-analysis could be performed. follow-up period of 22 months, although they did not dif-
Therefore, results are presented in a qualitative data ferentiate the intervention techniques according to the type
synthesis. of trauma (Song et al. 2017). Finally, the study by Cho et al.
(2018) described the clinical success of using flexible round
Quality assessment of included studies stainless steel wire and flowable composite resin (n = 137)
with different types of dental trauma (53, 84, and 15 teeth
Two independent reviewers (MSF and ABGA) appraised with root fracture, lateral and extrusive luxation, respec-
the quality assessment of observational studies using the tively) compared with children with traumatized teeth who
Newcastle–Ottawa Scale (N-OS) (Stang 2010). The N-OS did not receive splinting (control group) after more than six
contains eight items, categorized into three dimensions: months of follow-up (Cho et al. 2018).
selection, comparability, and outcome. A star scoring sys-
tem is used for semi-quantitative assessment of study quality. Quality assessment
Studies are graded one star each for all items except com-
parability, which has the potential to score up to two stars, All studies included in this review had a score < 5 (mean:
with the maximum possible score being nine. Studies are 4.3) in the N-OS criteria evaluation, and were classified as
rated from 0–9, with those studies rating 0–2 (poor quality), low quality (n = 3) (Cho et al. 2018; Kim et al. 2012; Song
3–5 (fair quality), 6–9 (good/high quality). Disagreements et al. 2017) (Table 2). Lower scores were mainly related
between the reviewers were resolved by discussion with to the lack of representativeness of the sample (selection
a third reviewer (MLG). All procedures in this step were domain) and the absence of a control group (comparability
checked by a third reviewer (HSS). In this evaluation step, domain).
the kappa coefficient between the two researchers was 0.93.
Synthesis of included studies
13
Table 1 Data extracted from the original retrospective studies
Author (year) country Sample (n)—age Type of trauma Splinting (type and durantion Control group Follow-up Main results
treatmeant)
13
(Cho et al. 2018) (n = 182 teeth) (1) Intra-alveolar root fracture Flexible round stainless steel Monitoring only (non- > 6 months Root fracture
Republic of Korea Mean age: 41.1 (SD 15.6) (n = 53) wire and flowable compos- intervention group Postoperative prognosis was
months (2) Lateral luxation (n = 107) ite resin n = 92) successful in 66.7% (n = 22)
(3) Extrusive luxation Time of splinting depended of the splinted tooth and 30%
(n = 22) on factors, such as persis- (n = 6) in the monitoring only
tence of increased mobility, group (p = 0.012). Splinted
type of trauma and interfer- group was 4.67 times more
ence of nutritional habits likely to have a clinical
success than the observation
group (95% CI 1.406–15.484;
p = 0.012)
Luxation injuries
Splinting did not show a better
prognosis in luxation injuries.
In teeth with lateral luxa-
tion, prognostic success was
observed in 35.7% (n = 15) of
the teeth in spliting group and
38.5% (25) of teeth in obser-
vation only group (p = 0.839).
In teeth with extrusive
luxation, success was 13.3%
(n = 2) in splinting group and
57.1% (n = 4) in observation
only group (p = 0.054)
(Kim et al. 2012) (n = 16 teeth) Root fracture Semi-rigid (resin wire-splint) Not reported Mean Total resorption of the
Republic of Korea Mean age: 44.3 months Splinting time ranged from 4 23.6 months fractured root fragment was
to 8 weeks (mean 5.1) (between 14 observed in 14 of 16 immobi-
and 36) lized teeth, with a resorption
period of less than 10 months
Root-fractured primary teeth
can be maintained by reduc-
ing tooth mobility and immo-
bilizing with a semi-rigid
splint. The treatment success
rate was good and fractured
tooth were retained or physi-
ologically exfoliated without
pulp treatment
European Archives of Paediatric Dentistry
European Archives of Paediatric Dentistry
luxation
(22.2%)
teeth with root fractures that received splinting with a con-
trol group and revealed a difference between these groups;
the splinting group was 4.67 times more likely to have
Mean 22.1
> 6 months;
months
Not reported
Discussion
Flexibe wire and flowable
et al. 2018; Kim et al. 2012) and, on the other hand, the
use of splinting in teeth with lateral luxation and extrusion
showed no additional benefits than monitoring only (Cho
et al. 2018). A previous systematic review included 12 stud-
Mean age: 42.1 (SD 17.4)
ies and concluded that the studies generally indicate that the
prognosis is determined by the type of injury rather than
Author (year) country Sample (n)—age
Republic of Korea
13
European Archives of Paediatric Dentistry
Table 2 Methodological quality assessment of retrospective studies instability, associate the use of flexible retainer attached to
(Newcastle–Ottawa scale) adjacent teeth for fragment stabilization and subsequent fol-
Study Selection Compara- Outcome Total low-up of the healing process and monitoring of the pulpal
bility vitality for four weeks (Day et al. 2020). Studies that evalu-
ated the effect of splinting in the treatment of primary teeth
Cho et al. (2018) 2 – 3 5
with root fractures in this systematic review, regardless of
Kim et al. (2012) 1 – 3 4
fracture-related aspects, found that the use of this approach
Song et al. (2017) 1 – 3 4
can be a viable alternative to promote pulpal survival (Cho
Maximum scores: selection = 4; comparability = 2; outcome = 3; et al. 2018; Kim et al. 2012). A recent scoping review that
total = 9 gathered the findings from case reports and a retrospective
- domain not contemplated = score zero study highlighted that immediate repositioning and semi-
rigid splinting could be conservative methods to prevent
presence of occlusal interference, no intervention is recom- loss of traumatized primary teeth (Spinas et al. 2022). Yet,
mended. When there is the presence of a displaced coronary this finding should be interpreted with caution, in light of
fragment with major mobility and interfering with occlusion, the design of the included studies (Kahler and Heithersay
two approaches may be employed: (1) coronal extraction and 2008). Immobilized teeth with dislocation of the coronal
maintenance of the apical fragment for subsequent resorp- fragment have a lower tendency of healing than non-splinted
tion; or (2) cautious coronal repositioning and, in cases of teeth with no displacement (Andreasen et al. 2004). Thus,
13
European Archives of Paediatric Dentistry
it is suggested that the lower success rate may be directly not be reimplanted (Day et al. 2020), we did not evaluate
associated with the severity of dental trauma (Kahler and the outcomes of stabilizing teeth completely detached from
Heithersay 2008; Kahler et al. 2016), and reinforces the con- their sockets.
servative approach recommended. In cases of alveolar fractures in the primary dentition,
Regarding luxation injuries, options of interventions for overall, the management should be performed by (a) repo-
the management of luxated teeth include monitoring only, sitioning displaced bone segments that are mobile and/or
extraction, splinting, repositioning, and repositioning/splint- causing occlusal interference (Day et al. 2020), followed by
ing (Assunção et al. 2011). Given the benefits of providing (b) splinting with a flexible retainer on adjacent uninjured
a more conservative approach to traumatized primary teeth teeth for four w eeks3. This management seeks to promote
(Cunha et al. 2007), and avoiding unnecessary and addi- stable restoration of bone continuity to the prejury posi-
tional damage (Goswami et al. 2020), in most cases moni- tion (Day et al. 2020; McTigue 2009). No studies have been
toring only is the recommended management (Day et al. included evaluating patients with alveolar fracture, which
2020). Repositioning a traumatized tooth with an injured can be explained by the limited number of cases and difficul-
periodontal ligament is likely to increase the pressure that ties in performing studies in an urgency situation.
already exists in the nutrient vessels to the tooth, increas- No clinical or radiographic evidence of adverse effects to
ing the chances of ischemia and necrosis (Soporowski et al. the use of splinting was reported in any of the studies. It was
1994). Most luxation injuries heal spontaneously, and a not possible to evaluate if the types of splints and splinting
conservative approach in the immediate dental trauma man- duration were generally related to healing outcomes. Regard-
agement is recommended (Flores 2002). Thus, the current ing time, in primary teeth, IADT recommends four weeks of
international guidelines state that in cases of extrusive dis- splinting, regardless of trama type. In a study with perma-
location, extraction is recommended only if the tooth were nent teeth, Andreasen et al. reported that splinting for peri-
diagnosed with excessive or extruded mobility (above three ods greater than 4-weeks appeared to provide no beneficial
millimeters); otherwise, wait for natural repositioning under healing outcome for root-fractured teeth, thereby providing
monitoring. In intrusively dislocated primary teeth it is also evidence in support of the current guidelines.
recommended to wait for the spontaneous repositioning of Different dental splint materials have been described for
the tooth (independent of the direction of displacement). first aid treatment of dental trauma injuries. Wire-compos-
Nevertheless, monitoring is the main management approach ite splints, using metallic wires up to 0.4 mm are one of
for laterally dislocated teeth; however, in severe dislocation the most commonly mentioned for flexible fixation. Also,
cases, two treatment options are available: (1) extraction nylon-composite splints are known as flexible splints. Other
when there is a risk of aspiration or ingestion of the tooth; options have been suggested, such as plastic strip made
(2) cautious repositioning of the tooth to the original posi- from a bottle of a sterile sodium chloride, but no study was
tion using digital pressure and, if unstable in its new posi- found in primary dentition so far. All studies included in
tion, splint for 4 weeks using a flexible splint attached to the this review used flexible/semi-rigid splints. Noteworthy, a
adjacent uninjured teeth (Day et al. 2020). functional splint retains the tooth in the socket but is flexible
A cross-sectional study analyzed the distribution of enough to allow functional stimulation of the periodontium
the different types of treatment used for luxation injuries (Kahler and Heithersay 2008; Kahler et al. 2016). In accord-
(n = 1703) in Brazilian children between the ages of zero to ance, splinting decisions in the guidelines for treatment of
five years treated at an emergency service department for a traumatic injuries by the International IADT indicate a
decade. In general, the results highlighted that monitoring flexible splint for luxated, root-fractured teeth, and alveolar
(74%) and spliting fixation (9%) were the main approaches fracture. Also, the current trend for functional splints is sup-
of choice for the management of dislocations (Assunção ported in published reviews assessing trauma in permanent
et al. 2011). It is important to highlight that, even though dentition (Kahler and Heithersay 2008).
old (Andreasen et al. 2012; Flores 2002; Flores et al. 2001) During the selection of studies in this systematic
and current (Day et al. 2020) guidelines do not recommend review, eight case reports were identified that described
the use of splinting on extruded or intruded primary teeth, the outcomes associated with the use of splinting in
this practice is commonly reported (Di Giorgio et al. 2021; the management of traumatized teeth (Akin et al. 2011;
Shanmugam et al. 2011). In the study of Song, of a total of Bonanato et al. 2009; Chatzidimitriou et al. 2017; Di Gior-
1736 luxated teeth, 202 (13.2%) were treated with splinting. gio et al. 2021; Liu et al. 2013; Pathak et al. 2016; San-
The higher rate was observed for teeth with extrusive luxa- tos et al. 2021; Shanmugam et al. 2011). All case reports
tion (28.9%) and lateral luxation (22.2%), but splints were reported splinting as a viable technique for immobiliz-
also used in cases of intrusive luxation, concussion, subluxa- ing traumatized deciduous teeth, regardless of the type
tion, and avulsion. Moreover, considering that international of TDIs (lateral dislocation, intrusive root fracture, and
guidelines recommend that avulsed primary teeth should mandibular alveolar fracture) and the splinting technique
13
European Archives of Paediatric Dentistry
13
European Archives of Paediatric Dentistry
Assunção LR, Ferelle A, Iwakura ML, Nascimento LS, Cunha 2008;24(1):2–10. [Link]
RF. Luxation injuries in primary teeth: a retrospective study 00480.x.
in children assisted at an emergency service. Braz Oral Res. Kahler B, Hu JY, Marriot-Smith CS, Heithersay GS. Splinting of teeth
2011;25(2):150–6. [Link] following trauma: a review and a new splinting recommendation.
0200009. Aust Dent J. 2016;61(Suppl 1):59–73. [Link]
Bonanato K, Sardenberg F, Santos ER, Ramos-Jorge ML, Zarzar PM. adj.12398.
Horizontal root fracture with displacement in the primary denti- Kim G-T, Sohn M, Ahn HJ, Lee D-W, Choi SC. Intra-alveolar root
tion. Gen Dent. 2009;57(4):e31-34. fracture in primary teeth. Pediatr Dent. 2012;34(7):215E-218E.
Bourguignon C, Cohenca N, Lauridsen E, Flores MT, O’Connell Liu X, Huang J, Bai Y, Wang X, Baker A, Chen F, Wu LA. Conserva-
AC, Day PF, Tsilingaridis G, Abbott PV, Fouad AF, Hicks L, tion of root-fractured primary teeth–report of a case. Dent Trau-
Andreasen JO, Cehreli ZC, Harlamb S, Kahler B, Oginni A, Sem- matol. 2013;29(6):498–501. [Link]
per M, Levin L. International Association of Dental Traumatol- McTigue DJ. Managing injuries to the primary dentition. Dent Clin
ogy guidelines for the management of traumatic dental injuries: North Am. 2009;53(4):627–38. [Link]
1. Fractures and luxations. Dent Traumatol. 2020;36(4):314–30. 2009.07.002.
[Link] Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mul-
Chatzidimitriou K, Lygidakis NN, Lygidakis NA. Eva vacuum-formed row CD, Shamseer L, Tetzlaff JM, Moher D. Updating guidance
alternative splinting of alveolar fractures in primary dentition: a for reporting systematic reviews: development of the PRISMA
case report. J Clin Pediatr Dent. 2017;41(5):327–31. [Link] 2020 statement. J Clin Epidemiol. 2021;134:103–12. [Link]
org/10.17796/1053-4628-41.5.327. org/10.1016/j.jclinepi.2021.02.003.
Cho WC, Nam OH, Kim MS, Lee HS, Choi SC. A retrospective study Pathak A, Kaur J, Dogra M, Verma J, Jain K. Conservative manage-
of traumatic dental injuries in primary dentition: treatment out- ment of trauma to deciduous maxillary anterior teeth: a case
comes of splinting. Acta Odontol Scand. 2018;76(4):253–6. report. Int J Oral Health Med Res. 2016;3:206–9.
[Link] Patnana AK, Chugh A, Chugh VK, Kumar P, Vanga NRV, Singh S. The
Cunha RF, Pugliesi DM, Percinoto C. Treatment of traumatized prevalence of traumatic dental injuries in primary teeth: a system-
primary teeth: a conservative approach. Dent Traumatol. atic review and meta-analysis. Dent Traumatol. 2021;37(3):383–
2007;23(6):360–3. [Link] 99. [Link]
00478.x. Santos LV, da Hora KC, Alves AC. Successful minimally invasive
da Costa Santos CM, de Mattos Pimenta CA, Nobre MR. The PICO intervention in a primary central incisor after root fracture: a case
strategy for the research question construction and evidence report. Dent Traumatol. 2021. [Link]
search. Rev Lat Am Enfermagem. 2007;15(3):508–11. [Link] Shanmugam HV, Arangannal P, Vishnurekha C, Nichani MH,
doi.org/10.1590/s0104-11692007000300023. Vijayaprabha K. Management of intrusive luxation in the primary
Day PF, Flores MT, O’Connell AC, Abbott PV, Tsilingaridis G, Fouad dentition by surgical repositioning: an alternative approach. Aust
AF, Cohenca N, Lauridsen E, Bourguignon C, Hicks L, Andreasen Dent J. 2011;56(2):207–11. [Link]
JO, Cehreli ZC, Harlamb S, Kahler B, Oginni A, Semper M, Levin 2011.01325.x.
L. International Association of Dental Traumatology guidelines Song K, Nam OH, Kim M, Lee H, Kim K, Choi S. A retrospective
for the management of traumatic dental injuries: 3. Injuries in the study of luxation injuries in primary teeth: prognosis with splint-
primary dentition. Dent Traumatol. 2020;36(4):343–59. [Link] ing. J Korean Acad Pediatr Dent. 2017;44:194–9. [Link]
doi.org/10.1111/edt.12576. 10.5933/JKAPD.2017.44.2.194.
Di Giorgio G, Zumbo G, Saccucci M, Luzzi V, Ierardo G, Biagi R, Soporowski NJ, Allred EN, Needleman HL. Luxation injuries of pri-
Bossù M. Root fracture and extrusive luxation in primary teeth mary anterior teeth–prognosis and related correlates. Pediatr Dent.
and their management: a case report. Dent J (basel). 2021. [Link] 1994;16(2):96–101.
doi.org/10.3390/dj9090107. Spinas E, Di Giorgio G, Murgia MS, Garau V, Pinna M, Zerman N.
Flores MT. Traumatic injuries in the primary dentition. Dent Trau- Root fractures in the primary teeth and their management: a scop-
matol. 2002;18(6):287–98. [Link] ing review. Dent J (basel). 2022. [Link]
2002.00153.x. 50074.
Flores MT, Andreasen JO, Bakland LK, Feiglin B, Gutmann JL, Stang A. Critical evaluation of the Newcastle-Ottawa scale for the
Oikarinen K, Pitt Ford TR, Sigurdsson A, Trope M, Vann WF Jr, assessment of the quality of nonrandomized studies in meta-
Andreasen FM. Guidelines for the evaluation and management of analyses. Eur J Epidemiol. 2010;25(9):603–5. [Link]
traumatic dental injuries. Dent Traumatol. 2001;17(3):97–102. 1007/s10654-010-9491-z.
[Link]
Goswami M, Eranhikkal A. Management of traumatic dental injuries Publisher's Note Springer Nature remains neutral with regard to
using different types of splints: a case series. Int J Clin Pediatr jurisdictional claims in published maps and institutional affiliations.
Dent. 2020;13(2):199–202. [Link] oi.o rg/1 0.5 005/j p-j ourn
als-10005-1746. Springer Nature or its licensor (e.g. a society or other partner) holds
Goswami M, Rahman B, Singh S. Outcomes of luxation injuries to exclusive rights to this article under a publishing agreement with the
primary teeth-a systematic review. J Oral Biol Craniofac Res. author(s) or other rightsholder(s); author self-archiving of the accepted
2020;10(2):227–32. [Link] manuscript version of this article is solely governed by the terms of
Kahler B, Heithersay GS. An evidence-based appraisal of splint- such publishing agreement and applicable law.
ing luxated, avulsed and root-fractured teeth. Dent Traumatol.
13