UNIVERSITY OF CAMBRIDGE INTERNATIONAL EXAMINATIONS

General Certificate of Education Advanced Subsidiary Level and Advanced Level

BIOLOGY 9700/01
Paper 1 Multiple Choice May/June 2007
1 hour
Additional Materials: Multiple Choice Answer Sheet
Soft clean eraser
*8585139293*

Soft pencil (type B or HB is recommended)

READ THESE INSTRUCTIONS FIRST

Write in soft pencil.

Do not use staples, paper clips, highlighters, glue or correction fluid.
Write your name, Centre number and candidate number on the Answer Sheet in the spaces provided
unless this has been done for you.

There are forty questions on this paper. Answer all questions. For each question there are four possible
answers A, B, C and D.
Choose the one you consider correct and record your choice in soft pencil on the separate Answer Sheet.

Read the instructions on the Answer Sheet very carefully.

Each correct answer will score one mark. A mark will not be deducted for a wrong answer.
Any rough working should be done in this booklet.

This document consists of 17 printed pages and 3 blank pages.

IB07 06_9700_01/5RP
© UCLES 2007 [Turn over
 2

1 The diameter of living cells varies considerably.

Typical diameters are:

a prokaryote, such as Streptococcus - 750 nm

a eukaryotic cell, such as a white blood cell - 15 µm

Given these measurements, the diameter of the white blood cell is how many times greater than
the prokaryote?

A x2 B x 20 C x 50 D x 200

2 In constructing a plan diagram of a transverse section of a dicotyledonous leaf, which feature

should not be included?

A chloroplasts in the palisade mesophyll layer

B cuticle on the upper epidermis
C vascular bundles in the leaf lamina
D xylem in the vascular bundles

3 Membranous sacs containing products of metabolism are formed by the endoplasmic reticulum in
cells.

Where are these products used?

A inside and outside the cell

B inside lysosomes only
C inside the cell only
D outside the cell only

© UCLES 2007 9700/01/M/J/07

 3

4 The diagram shows a graduated slide, with divisions of 0.1 mm viewed using an eyepiece
graticule.

0 10 20 30 40 50 60 70 80 90 100

Pollen grains were grown in a sugar solution and viewed using the eyepiece graticule. Diagram 1
shows the pollen grains at first and diagram 2 shows them after four hours.

diagram 1 diagram 2

0 10 20 30 40 50 60 70 80 90 100 0 10 20 30 40 50 60 70 80 90 100

at start after 4 hours

What is the growth rate of the pollen tubes?

A 5 µmh–1 B 10 µmh–1 C 5 mmh–1 D 10 mmh–1

5 In 1985, a giant bacterium, Epulopiscium fishelsoni, was discovered.

Which cell structure(s) would be present in Epulopiscium enabling biologists to classify this
organism as prokaryotic?

A a cellulose cell wall outside the plasma membrane

B a pair of centrioles close to the nuclear area
C circular DNA lying free in the cytoplasm
D smooth endoplasmic reticulum throughout the cytoplasm

© UCLES 2007 9700/01/M/J/07 [Turn over

 4

6 This molecule is a polymer of reducing sugars.

CH2OH CH2OH CH2OH CH2OH

O O O O

HO OH O OH O OH O OH OH
OH OH OH OH

Which of the following procedures could be carried out in order to test for the presence of the
reducing sugars in this molecule?

1 add hydrolytic enzyme and then heat with Benedict’s reagent

2 dissolve in water, neutralise and then heat with Benedict’s reagent
3 boil with ethanol and then heat with Benedict’s reagent
4 boil with hydrochloric acid, neutralise and then heat with Benedict’s reagent

A 1 and 2
B 1 and 4
C 1, 2 and 4
D 1, 2, 3 and 4

7 Which correctly matches the functional and structural features of cellulose, collagen, glycogen
and triglyceride?

structure

molecule held
function fibrous together by branched chains
hydrogen bonds

A cellulose support   
collagen strengthening   
B cellulose support   
triglyceride energy source   
C collagen strengthening   
glycogen storage   
D glycogen storage   
triglyceride energy source   

© UCLES 2007 9700/01/M/J/07

 5

8 Which describes the structure of amylopectin?

A a branched chain with 1,2 and 1,4 glycosidic bonds

B a branched chain with 1,4 and 1,6 glycosidic bonds
C an unbranched chain with only 1,4 glycosidic bonds
D an unbranched chain with 1,4 and 1,6 glycosidic bonds

9 Which molecule is found in glycogen?

A B

H CH2OH

H C OH C O
H H H
H C OH C C
OH H
HO OH
H C OH C C

H H OH

C D

CH2OH O
CH2OH H
C O
H OH C C
H H CH2OH
C C H OH
OH H
HO H C
C
C C
OH H
H OH

10 High concentrations of urea break all bonds, except covalent bonds, in protein molecules.

Which level of protein structure would remain unchanged when a protein is treated with urea?

A primary
B secondary
C tertiary
D quaternary

© UCLES 2007 9700/01/M/J/07 [Turn over

 6

11 Which bonds are the last to break when an enzyme is heated?

A disulphide
B hydrogen
C hydrophobic interactions
D ionic

12 During the production of apple juice, enzymes are used to break down the components of the cell
walls.

Which carbohydrate will be produced by this hydrolysis?

A amylose
B cellulose

C α glucose

D β glucose

13 The rate of enzyme catalysed reactions in human cells is regulated.

Which of the following may be involved in such regulation?

1 a change in enzyme concentration

2 a change in substrate concentration
3 inhibition by the final product of the reaction

A 1 only
B 3 only
C 1 and 2 only
D 1, 2 and 3

© UCLES 2007 9700/01/M/J/07

 7

14 The diagrams show two kinds of molecules found in cell surface membranes.

Which part affects the fluidity of the membrane?

D C

© UCLES 2007 9700/01/M/J/07 [Turn over

 8

15 The graphs show the rate of uptake of sugars by a culture of animal cells, under different
conditions.

air bubbled through the culture

3-carbon sugar

rate of
uptake 6-carbon sugar

0 10 20 30

temperature / °C

nitrogen gas bubbled through the culture

3-carbon sugar

rate of
uptake

0 6-carbon sugar
0 10 20 30

temperature / °C

How are the sugars taken up by the cells when air is bubbled through the culture?

3-carbon sugar 6-carbon sugar

A active transport active transport

B active transport diffusion
C diffusion active transport
D diffusion diffusion

16 Which process allows the movement of molecules that are too large to pass in through a cell
surface membrane?

A active transport
B endocytosis
C exocytosis
D facilitated diffusion

© UCLES 2007 9700/01/M/J/07

 9

17 Which structure organises spindle formation during mitosis in animal cells?

A centriole
B centromere
C nucleolus
D nucleus

18 Which processes involve mitosis?

A growth, reduction division and asexual reproduction

B growth, repair and asexual reproduction
C growth, repair and semi-conservative replication
D repair, reduction division and asexual reproduction

19 The graph represents the changes in the quantity of DNA present in one nucleus at different
stages in the life cycle.

X
fertilisation

4
relative DNA
content
egg

time

Which stage takes place at X?

A interphase
B metaphase
C prophase
D telophase

© UCLES 2007 9700/01/M/J/07 [Turn over

 10

20 Which type of sugar and bonds are found in a DNA molecule?

bonds linking
type of sugar
complementary bases

A hexose hydrogen
B hexose peptide
C pentose hydrogen
D pentose peptide

21 A length of double-stranded DNA contains 120 nucleotides and codes for polypeptide X.

What is the maximum length of polypeptide X?

A 20 amino acids
B 40 amino acids
C 60 amino acids
D 120 amino acids

22 In a DNA molecule, the base sequence AGT codes for the amino acid serine.

What is the base sequence of the anti-codon on the tRNA to which serine becomes attached?

A AGU
B GAU
C TCA
D UCA

23 What occurs in the apoplast and symplast pathways?

water water enters water water moves from water moves from
enters cell cytoplasm through enters cell to cell through cell to cell through
wall plasma membrane vacuoles plasmodesmata intercellular spaces

A apoplast apoplast apoplast symplast symplast

B apoplast symplast symplast symplast apoplast
C symplast apoplast apoplast apoplast symplast
D symplast symplast symplast apoplast apoplast

© UCLES 2007 9700/01/M/J/07

 11

24 In an animal cell, which process is dependent upon cell surface area and which process is
dependent upon cell volume?

cell surface area cell volume

A carbon dioxide produced oxygen used

B glucose absorbed hormones detected
C hormones detected carbon dioxide produced
D oxygen used glucose absorbed

25 The diagrams show transverse sections of parts of a plant.

leaf stem root

3
1
4 5

In the cross sections, what do 1, 2, 3, 4, 5 and 6 represent?

leaf stem root

phloem xylem phloem xylem phloem xylem

A 1 2 3 4 5 6
B 1 2 4 3 6 5
C 2 1 3 4 5 6
D 2 1 4 3 6 5

© UCLES 2007 9700/01/M/J/07 [Turn over

 12

26 Land flooded by the sea is not suitable for growing plants long after the salty flood water has
drained away.

The diagram represents a transverse section through a part of the root of a plant.

cortex
xylem
soil water

Which values of water potential (kPa) in the xylem and soil water help to explain why the land
flooded with salty water is unsuitable for growth of plants?

xylem soil water

A –700 kPa 0 kPa

B –1800 kPa –700 kPa
C 0 kPa –1800 kPa
D –700 kPa –1800 kPa

27 In mammals, some carbon dioxide is transported by red blood cells in combination with
haemoglobin.

What is the product of this combination?

A carbamino-haemoglobin
B carbonic acid
C carboxyhaemoglobin
D haemoglobinic acid

© UCLES 2007 9700/01/M/J/07

 13

28 A red blood cell, entering the right side of the heart, passes by or through the following structures.

1 atrioventricular valve
2 semilunar valve
3 right atrium
4 right ventricle
5 sinoatrial node

In which order will the red blood cell pass the structures?

A 3→1→4→5→2

B 3→5→1→2→4

C 5→3→1→4→2

D 5→3→2→4→1

29 What correctly describes the cause and effect of carcinogens on lung tissue?

A Cells of the alveoli walls divide more rapidly than normal by reduction division causing a
tumour to develop.
B Cilia are paralysed, mucus accumulates in the lungs, causing DNA to change, reduction
division and a tumour to develop.
C DNA changes, causing bronchial epithelial cells to divide in an uncontrolled way by mitosis
and a tumour to develop.
D Haemoglobin carries less oxygen, causing bronchial cells to divide in an uncontrolled way by
mitosis and a tumour to develop.

30 What is a correct description of part of the respiratory system?

ciliated smooth
part of respiratory cartilage goblet cells
epithelium muscle
system present present
present present

A alveolus    
B bronchus    
C bronchiole    
D trachea    

© UCLES 2007 9700/01/M/J/07 [Turn over

 14

31 Which statement describes the vital capacity of a human lung?

A the additional volume of air that can be exhaled after breathing out normally
B the additional volume of air that can be inhaled after breathing in normally
C the volume of air inhaled and then exhaled during a single tidal breath
D the volume of air that can be exhaled following a maximum inhalation

32 Which statement explains why people suffering from malaria and people suffering from
tuberculosis can both live in northern Europe, but only tuberculosis can be passed on to other
people there?

A Anopheles mosquitoes only breed in sub-tropical and tropical areas.

B Antibiotics can be used to cure people with tuberculosis.
C Migrant workers can carry the diseases with them.
D Tuberculosis bacteria cannot survive in sub-tropical and tropical areas.

33 The diagram shows the effects of the antibiotics streptomycin and penicillin on the bacterium
Escherichia coli.

colonies of
E. coli
S disc of filter paper
S soaked in a solution
of streptomycin

petri dish disc of filter paper

P P soaked in a solution
into which
nutrient agar of penicillin
containing
E. coli has
been poured

What can you deduce about the response of E. coli to the effects of the antibiotics?

completely resistant not completely resistant

A S and P –
B S P
C P S
D – S and P

© UCLES 2007 9700/01/M/J/07

 15

34 The diagram refers to properties of diseases.

Which area of the diagram refers to properties that are common to both tuberculosis and
cholera?

A
bacterial infectious

D
C B

transmitted
by water

35 What causes the measles vaccine to be less effective in children from less economically
developed countries?

A Their diet does not contain enough carbohydrate.

B Their diet does not contain enough protein.
C They are carriers of the disease.
D They rapidly become reinfected.

36 What is the function of the plasma cells during an immune response?

A to secrete antibodies
B to engulf bacteria
C to kill cells infected with viruses
D to change into memory cells

© UCLES 2007 9700/01/M/J/07 [Turn over

 16

37 The graph shows the amount of antibody produced in response to an antigen.

concentration
of antibodies
in the blood

0 10 20 30 40
time in days

first exposure to an antigen

From the graph, which statement is correct?

A It takes 25 days to achieve active immunity.

B Memory cells for this antigen are present in the body within 20 days.
C T helper cells are activated on day 12.
D The second exposure to the antigen occurred on day 25.

38 What limits the number of trophic levels in a food chain?

A biomass of the autotrophs

B efficiency of energy conversion between levels
C net productivity of the ecosystem
D species diversity in the ecosystem

© UCLES 2007 9700/01/M/J/07

 17

39 The following are definitions of three ecological terms.

1 all of the organisms and their environment

2 group of individuals of one species living in an area
3 all of the organisms living in a habitat

What are the correct definitions of a community and a population?

community population

A 1 2
B 2 1
C 3 1
D 3 2

40 The diagram shows the circulation of nitrogen in nature.

nitrogen
in the air
3
2

lightning
ammonium organic
nitrate in nitrogen
1 fertiliser NO in legumes

plants NH4+
5
in soil

nitrate animals
in soil
nitrite
in soil
4 4

What is correct?

denitrification nitrification nitrogen fixation

A 1 4 5
B 2 5 4
C 3 2 1
D 1 4 3

© UCLES 2007 9700/01/M/J/07

 18

BLANK PAGE

9700/01/M/J/07
 19

BLANK PAGE

9700/01/M/J/07
 20

BLANK PAGE

Permission to reproduce items where third-party owned material protected by copyright is included has been sought and cleared where possible. Every
reasonable effort has been made by the publisher (UCLES) to trace copyright holders, but if any items requiring clearance have unwittingly been included, the
publisher will be pleased to make amends at the earliest possible opportunity.

University of Cambridge International Examinations is part of the Cambridge Assessment Group. Cambridge Assessment is the brand name of University of
Cambridge Local Examinations Syndicate (UCLES), which is itself a department of the University of Cambridge.

9700/01/M/J/07