1)Chylomicrons are small particles of dietary fats found in variable size, formed in

intestinal epithelial cells and transported in blood plasma and lymph

A.True

B.False

2)White adipocyte tissue :

A.Contains mitochondria and a small Golgi apparatus

B.They are crescent in shape

C.Are surrounded by a thin external lamina containing type VI collagen

D.Contains a multiple small droplets of lipid that lls almost the entire cell

E.None of the choices describe the white adipose tissue

3) Leptin is:

A.Regulate the appetite under normal conditions

B.Regulating the formation of new adipose tissue

C.All choices correct

D.Polypeptide hormone

E.Two choices correct

4) All of the following are correct about brown adipose tissue EXCEPT :

A.Adipocytes of brown fat contain many small lipid inclusions

B. This tissue's principal function of heat production by shivering thermogenesis

C.Adipocytes of brown fat are often closely packed around large capillaries

D.It found around the kidney

E.Brown adipose tissue constitutes up to 5% of the newborn body weight

5)Dietary fats are transported as

A.very-low-density lipoproteins

B .Lipid globules

C.Liposomes

D.Free fatty acid

E.Chylomicron

6)Synthesis of adipocytes from glucose is accelerate by:

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A.Two choices correct

B.Leptin

C.Insulin

D.Vimentin

E.Glucagon

7)The brown fat :

A.Two of the above are correct

B.Brown adipose tissue in newborn body located mainly in the back, neck, and shoulders

C.All of the above are correct

D.Produce heat by non-shivering thermogenesis

E.Amount of brown fat is maximal relative to body weight at puberty

8)Vimentin is:

A. Interwoven network that supports individual fat cells

B.Intermediate laments

C. The incomplete lobules in the adipose tissue

D. None of the choices correct

E. A thin external lamina containina tvpe IV collagen

9)Triglycerides synthesized in the liver called

A.Lipoproteins

B.Very-low-density lipoproteins

C.Apolipoproteins

D.Chylomicrons

E.vementin

10)Which of the following connective tissue cell types is not typical of lamina propria?

A.Fibroblast

B.Lymphocyte

C.Adipocyte

D.Mast cell

E.Macrophage
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11)The tissue which is found in abdomen, around kidneys and under skin is called :

A.Nerve tissue

B.Cardiac tissue

C.Skeletal tissue

D.Adipose tissue

E.None of the choices correct

12)What type of adipose tissue tends to increase as humans age?

A.Brown adipose tissue

B.White adipose tissue

C.Unilocular adipose tissue

D.Multilocular adipose tissue

E. Both B and C

13)What type of adipose tissue tends to decrease as humans age?

A.Brown adipose tissue

B.White adipose tissue

C.Unilocular adipose tissue

D.Multilocular adipose tissue

E.Both A and D

14)Dietary fats are transported as very-low-density lipoproteins:

A.Lipid globules

B.Liposomes

C.Chylomicrons

D.Free fatty acid

15)Triglycerides synthesized in the liver called

A.Lipoproteins

B.Very-low-density lipoproteins

C.Chylomicrons

D.Apolipoproteins

E.Vimentin
16)What promotes triglycerides breaking into fatty acids?

A.Glucagon

B.Vimentin

C.Insulin

D.Leptin

17)All of the following are correct about histogenesis of white adipose tissue EXCEPT

:A- Development of new adipocytes continues postnataly around small blood vessets.

B- White adipose tissue accumulates at week.20 of gestation

C- Adult-onset obesity mainly involves increased size of existing adipocytes

D- Childhood obesity can involve increases in both adipocyte size and numbers due to
differentiation of more preadipocytes from mesenchymal stem cells

E- Excessive formation of adipose ussue occurs when energy intake exceeds energy
expenditure

18)Which of the following is correct about white adipose tissue?

A- Reticular bers form a ne interwoven network that supports individual fat cells and
binds them together

B- White adipocytes are called multilocular

C- Adipocytes of white adipose tissue are polyhedral when isolated but are spherical when
closely packed in situ

D- The distribution of this tissue changes signi cantly through childhood and adult life and
is partly regulated by growth hormones

E- They are a large cell with maximum size of 200 um in diameter

19)All the following are correct about the white adipose tissue EXCEPT:

A- Children obesity is more danger than the adult obesity

B- During starvation, the fate in palms, soles, and retro-orbital fat pads resists for long
periods and remain for last

C- Preadipocytes cells have the appearance of broblasts but accumulate lipid droplets in
their gytoplasm

D- White adipose tissue begins to accumulate at week 30 of gestation

E- Adipocytes of fatty acids from glucose is accelerated by growth hormone

20)In a slide showing spongy bone formed solely by intramembranous ossi cation, all of
the following features may be found upon microscopic examination except:
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A.Calcifed cartilage

B.Lamellar bone

C.Periosteum

D.Non-lamellar bone

E.Osteoclasts

21)All of the following are correct about the cartilage EXCEPT:-

A.It can with stand considerable pressure, pull and torsion

B.It is form of connective tissue

C.Cartilage guides development and growth of long bones, both before and after birth

D.Height of the body is more in early morning due to more accumulation of uid in
cartilage tissue

E.It supplies by nerve

22)A common location for elastic cartilage:

A.Tip of nose

B.Two choices correct

C.All choices correct

D.External ear

E.Intervertebral disc

23)The presence of which one of the following characteristics is of least value

indistinguishing bone from hyaline cartilage?

A.Haversian canals

B.Lamellae

C.Cell nests

D.Canaliculi

E.Lacunae

24)All of the following are correct about the chondrocytes EXCEPT:

A .It is basophilic

B.The cells only found as a single cell within the matrix

C.It synthesis type I collagen

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 D.The cells found in a space called lacuna

E.It synthesis proteoglycan

25)The territorial matrix:

A.All choices correct

B.Two choices correct

C.The area of lighter basophilia is the inter-territorial zone

D.Contain both the lacuna and the chondrocyte cell

E.Contain less collagen than the surrounding area

26)All of the following are correct about the Fibrocartilage EXCEPT:

A- Have chondrocytes organized in rows

B- Has no perichondrium

C-It has a matrix with large bundles oftype I collagen in addition to type III

D- Is found in the meniscus of the knee joint

E- It is mainly a combination of hyaline cartilage and dense connective tissue with gradual
transitions between these tissues

27)The perichondrium is:

A.Dense brous connective tissue

B.All choices incorrect

C.Yellow elastic connective tissue

D.Loose areolar connective tissue

E.Reticular connective tissue

28)All of the following are correct about chondrogenesis EXCEPT

A- Mesenchyme is the precursor of the elastic cartilage

B- The precursor cells differentiate into chondroblasts

C- Chondroblasts are separated from one another by their production of various matrix
companents

D-All choices are correct

E- Except in adults, damaged cartilage undergoes slow and often incomplete repair,
primarily byactivity of cells in the perichondrium, which invade the injured area and
produce new cartilage
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29)All of the following are correct about the elastic cartilage EXCEPT:

A.Two choices are correct

B.Perichondrium of the elastic cartilage similar to that of most hyaline cartilage

C.Found in the auricle of the ear

D. Contains an abundant network of elastic bers

E.All choices are correct

30) All of the following are correct about the hyaline cartilage EXCEPT:

A.All choices are correct

B.Most common type of cartilage

C.Cartilage has the major role in embryonic life than adult's life

D.It is semitransparent in the fresh state

31)Fibrocartilage lacks an identi able perichondrium

A.True

B.False

32)The epiglottis is containing ?

A Fibrocartilage

B.Hyaline cartilage

C.Elastic cartilage

33)The articular surface of joints is ?

A.Is rich in elastic bers

B.Is formed of hyaline cartilage

C.Gets its nutrition from periosteum

D .Is rich in collagen type I

E. Gets its nutrition from perichondrium

34)Chondroblasts would be associated with

A.Developing cartilage

B.Mesenchyme

C.Developing bone
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D.Mature bone tissue

E.Cartilage maturation

35)Tissue that is avascular and as a result is slow to heal is

A.Cartilage

B.Nerve

C.Bone

D.Adipose

36)Regarding cartilage, which is true?

A.The intervertebral discs contain hyaline cartilage

B.Chondroblast located at the lines border between Perichondrium and matrix

C.Elastic cartilage is the commonest type

D.Perichondrium composed of collagen type II

37)Chondrocytes:

A.Are housed in lacunae

B.Derive from broblasts

C.Mitotic divisions are responsible for interstitial growth

D.Synthesize extra cellular matrix

E.Are precursors of chondroblasts

F.A+B

G.A+C

H.All is correct

38)Which of the following is correct about aggrecan??

A.It is a proteoglycan

B.It has a core of many chondroitin sulfate and keratan sulfate chains

C.It is a Glycosaminoglycans

D.Two choices correct

E.It is a multiadhesive glycoproteins

39)The cartilage with no perichondrium is:

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A.Fibrocartilage

B.Hyaline cartilage

C.Articular cartilage

D.Elastic cartilage

40) What cell produces the cartilaginous matrix?

A.Chondrocyte

B.Chondroblast

C.Osteocyte

D.Osteoclast

E.Bone lining cell

41)Which of the following is NOT a glycosaminoglycan in cartilage?

A.Chondroitin sulfate

B.Proteoglycans

C.Keratan sulfate

D.Hyaluronic acid

E.All of the above are glycosaminoglycans in cartilage

42)Which type of cartilage is characterized by the presence of chondrocytes sitting in

lacunae?

A.Hyaline cartilage

B.Elastic cartilage

C.Fibrocartilage

D.All of the above

43)What structure is called white cartilage?

A.Hyaline cartilage

B.Elastic cartilage

C.Fibrocartilage

D.Compact bone

E.Spongy bone

44)Where does cartilage come from?

A.Ectoderm
B.Endoderm

C.Mesenchyme

D.Connective tissue

E.None of the above

45)Which type of cartilage is present in the temporomandibular joint?

A.Hyaline cartilage

B.Elastic cartilage

C.Fibrocartilage

D.All of the above

E.None of the above

46)In hyaline cartilage matrix is

A.Semi transparent

B.Agranular

C.Transparent

D.Liner

47)The type of collagen in perichondrium

A.Type I

B.Type II

C.Type III

D.Type IV

48)Fibrocartilage characteristics

a. Lack inde nite perichondrium.

b. It contains collagen type II.

49)Elastic cartilage is found in which of the following:

a. eustachian tube

b. Intervertebral discs
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c. attachments of certain ligaments

d. pubic symphysis.

50)All of the following are correct about the platelets EXCЕРТ :

A.Circulating platelets have a life span of about 10 days

B.They are a non-nucleated cell

C Normal platelet counts range from 150,000 to 400,000/pL (mm3) of blood

D.They are a membrane bounded cell

E.Platelets has a dark central zone called hyalomere

51) Which of the following polypeptides directing activities of leukocytes and other cells of
the immune system?

A. Heparin

B.Serine proteases

C.histamine

D.cytokines

E.all choices correct

52)All of the following are correct about erythrocytes except

A.The only blood cells whose function does not require them to leave the vasculature

B.Erythrocytes with normal adult hemoglobin frequently assume a cuplike shape

C.The normal concentration is 4.1-6.0 million/uL in women

D.Erythrocytes are normally quite exible

E.They are 2.6 um thick at the rim

53)Which leukocyte has red-pink granules ?

A lympohcytes

B.neutrophil

C.monocytes

D.eosinophils

E.basophils
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54)which blood cells secrete antibodies

A.basophile

B.lymphocyte

C.monocyte

D.neutrophil

E.eosinophil

55)Which of the following is a granulocyte ?

A .basophil

B.lymphocyte

C.thrombocyte

D.erythrocyte

56)The phagocytic cells that found in the skin called:

A.Langerhans cells

B.Dust cells

C.Microglia cells

D.Kupffer cells

E.Ostroclast cells

57)How many percent of all leucocytes in healthy individuals are lymphocytes?

A.0.5%

B.30%

C.54%

D.45%

E.50

58)Which of the following formed elements do not contain a nucleus ?

A. erythrocytes

B.monocytes

C.leukocytes

D.2 choices are correct

E.platelets

59)The largest plasma protein is

A.Albumin

B.a-Globulins

C.none of these are the largest plasma protein

D.y-Globulins

E.Fibrinogen

60)Blood is considered a connective tissue because

A.It connects parts of the body together

B.All choices incorrect

C.It arises from mesenchymal tissue and has a nonliving uid matrix

D.It contains broblasts

61)Which leucocytes release heparin and histamine in blood?

A.monocyte

B.lymphocyte

C.basophil

D.eosinophil

E.neutrophil

62)All of the following are a xed cell EXCEPT:

A.Mast cells
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 B.Fat cells

C .Macrophages

D.Undifferentiated stem cells

E.Fibroblasts

F.all of the following are correct

63)y-Globulins is:

A.The largest plasma protein

B.Immunoglobulins secreted by plasma cells

C.Serves primarily to maintain the osmotic pressure of thei blood

D.The most abundant plasma protein

64)Humoral immunity is a type of adaptive immunity that results in the circulation of which
of the following throughout the blood?

A.Natural killer cells

B.Antibodies

C.Macrophage

D.antigen

65)which of the following plasma protein transport metal ions ?

A.None of these correct

B brinogen

C.globulins

D.albumin

66)Release in ammatory molecules like the histamine?

A.Fibroblasts

B.Plasma cells

C.Macrophages

D.Mast cells
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 67)which of the following cells begin the healing process

A.macrophages

B. broblasts

C.leukocytes

D. mast cells

E plasma cells

68)All af the following are correct about blood EXCEPT

A.All choices are correct

B.The plasma solutes about 1% of the plasma total volume

C.The platelets and WBCs make about 1% of the blood total volume

D.The average volume of the adult blood about 5 litters

E.Water is made about 92% of the plasma total volum

69)Monocytes move from the systemic ciraulatory system into general connective tissues.
where they differentiate into what phagocytic cell type?

A.T-cells

B.B-cells

C.Langerhans cells

D.Macrophage

E.kupffer cells

70)How many percent of all leucocytes in healthy individuals are neutrophils

A.60%

B.30%

C.5%

D.0.5%

E.43%
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71)"Plasma" contains water along with important

A.White blood cells

B.Food chemicals

C Red blood cells

D.all choices correct

E.Platlet

72)Hemoglobin "is a combination of :

A Fats and proteins

B.Proteins and iron

C.Carbohydrates and fats

D.Carbohydrates and protein

73)The only connective tissue without broblasts is:

A Areolar connective tissue

B.blood

C. bone

D. cartilage

74) How many percent of all leucocytes in healthy individuals are lymphocytes?

A.0.5%

B.30%

C.45%

D.54%

75)All of the tollowing are corect about the plasma cells EXCEPT :

A.Plasma cells are lymphocyte derived

B.As they synthesize antibodies they are protein synthesizing cells

C.The nucleus of the plasma cell is generally spherical but eccentrically placed

D.They are about 20 um in diameters

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 E.The life spam from 10 to 20 days

76)Identily the INCORRECT statement

A- The inactive X chromosome may appear as a drumstick-like appendage on the lobe of

the nucieus of the basophilic cell

B- Most of the lymphocytes in the blood stream will be 8-lymphocytes

C- Human blood platelets have, in contrast to red blood cells, never been individual
nucleated cells

D- Circulating platelets have a life span of about 90 days

E- Two statements incorrect

77)The biconcave shape of RBCs is bene cial because it :

A- Prevents diapedesis of RBCs through the walls of the blood capillaries

B- Makes the RBCS more exible so they can pass and bend through the smaller blood
vessels more easily

C.Increases the ratio of cell surface area to volume of the cell and allows for increased
diffusion of oxygen

D Allows more space for the mature RBCs to accommodate the nucleus E- Two choices
correct

78)which of the following plasma protein transport metal ions?

A.albumin

B.none

C. bronogen

D.globulins

79)Which connective tissue cell is derived from B lymphocytes ?

A.Fibroblast

B.Myo broblast

C.Histiocyte

D.Plasma cell
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E.Mast cell

80)Which of the following formed elements do not contain a nucleus?

A.platelete

B.erythrocyte

C.leukocytes

D.monocytes

E.a and b

81)Which of the following is not considered a "formed element"?

A.plasma

B.erythocytes

C.platelete

D.leukocyte

E. RBC

82)Which of the following use granulocyte?

A.Thrombocyte

B.Monocyte

C.Lymphocyte

D Basophil

E.Erythrocyte

83)Which of the following is described as having a "central pallor" ?

A.leukocytes

B.monocytes

C.eosinophils

D.platelete

E.erythrocytes
84)Which is the smallest leukocyte?

A.neutrophil

B.lymphocytes

C.monocytes

D.eosniphil

85)What is the buffy coat?

A platelete

B.leukocytes

C.erythrocytes

D.both a and b

86)Which leukocyte is the second most abundant in a peripheral smear ofblood?

A.lymphocytes

B basophils

C.neutrophil

D.monocytes

87)Which is the largest leukocyte?

A.neutrophil

B.lymphocytes

C.monocytes

D.eosniphil

88)which of the following formed elements do not contain a nucleus:

A.Erythrocytes

B.Monocytes
C.Leukocytes

D.Two of the choices correct

E.platelets

89)which of the following are correct about EXCEPT:

A.The plasma solutes about 1% of the plasma total volume

B.The platelets and WBC's make about 1% of the blood total volume

C.The average volume of the adult blood about 5 lires

D.Water is made of 92% of the plasma total volume

E.All choices are correct

ANSWERS :

1-A 2-A 3-C 4-B 5-E 6-C 7-A 8-B 9-B 10-C 11-D 12-E 13-E 14-C 15-B 16-A 17-B 18-A 19-E

20-A 21-E 22-B 23-E 24-C 25-A 26-C 27-A 28-E 29-E 30-A 31-A 32-C 33-B 34-A 35-A 36-B
37-G 38-D 39-C 40-B 41-C 42-D 43-C 44-C 45-C 46-A 47-A 48-A 49-A

50-E 51-D 52-C 53-D 54-B 55-A 56-A 57-B 58-D 59-E 60-C 61-C 62-F 63-B 64-B 65-C 66-
D 67-D 68-A 69-D 70-A 71-B 72-B 73-A 74-B 75-A 76-E 77-E 78-D 79-D 80-E 81-A 82-D
83-E 84-B 85-D 86-A 87-C 88-D 89-E