Esquizoq Articulo3
Esquizoq Articulo3
Esquizoq Articulo3
Eduardo Fonseca-Pedrero1
Marta Santarén-Rosell1
Psychotic-like experiences in the
Serafín Lemos-Giráldez1 adolescent general population
Mercedes Paino1
Susana Sierra-Baigrie1
José Muñiz1
1
Psychology Department
Universidad de Oviedo
Centro de Investigación Biomédica en Red de Salud Mental
CIBERSAM
Objective. The main purpose of this study was to analyze nuados en población adolescente no clínica. Asímismo,
the distribution of psychotic-like experiences in nonclinical se profundizó en el papel que desempeñan el sexo y la
adolescents. Likewise, we studied in depth the role of gender edad en la expresión fenotípica de dichas experiencias.
and age in phenotypal expression of these symptoms.
Método. En el estudio participaron un total de 1.438
Method. A total of 1438 adolescents entered the study, 691 adolescentes, 691 (48,1 %) varones, con una edad media
(48.1%) were men, with a mean age of 15.9 years (SD = 1.2). de 15,9 años (DT = 1,2).
Results. The results indicated that attenuated psychotic Resultados. Los resultados mostraron que los sínto-
symptoms are a very common phenomenon in this age mas psicóticos subclínicos son un fenómeno bastante co-
group, since 43% of the sample reported symptoms belonging mún dentro de este grupo de edad. El 43% de la muestra
to magical thinking, ideas of reference, and/or delusion or informó de algún síntoma relacionado con el pensamien-
hallucination experiences, and 8.9% reported 4 or more to mágico, la ideación referencial y/o las experiencias
psychotic-like experiences. Statistical significant differences delirantes o alucinatorias. El 8,9% refirió 4 o más expe-
were found in ideas of reference and paranoid ideation riencias psicóticas subclínicas. Se encontraron diferen-
cias estadísticamente significativas en función del sexo
between genders, but not among age groups.
en ideación referencial e ideación paranoide, en cambio
no se hallaron diferencias estadísticamente significativas
Conclusion. Our results coincide with those found in
en función de la edad.
previous studies and have clear implications for a better
understanding of these psychological phenomena in the
Conclusión. Estos resultados son convergentes con los
framework of developmental psychopathology, and for the
datos encontrados en la literatura previa y tienen claras
implementation of early detection and prevention programs implicaciones de cara a la comprensión de este fenómeno
in the population sector. psicológico dentro de los modelos de psicopatología del
Keywords:
desarrollo, así como en lo relativo al establecimiento de
Schizotypy, Psychosis, Subclinical Symptoms, Adolescents, Psychotic-like experiences, Risk. programas de prevención y detección temprana en este
sector de la población.
Actas Esp Psiquiatr 2011;39(3):155-62
Palabras clave:
Esquizotipia, Psicosis, Síntomas Subclínicos, Adolescentes, Experiencias psicóticas,
Riesgo.
Síntomas psicóticos subclínicos en población
general adolescente
below the clinical threshold or is not necessarily associated (ESQUIZO-Q)22 (Oviedo Questionnaire for the Evaluation of
with a psychopathological, medical disorder or disorder of Schizotypy) in a sample of 1653 adolescents, found that from
another type.3 Within the dimensional models of psychosis, 2.7% to 17.4% of the participants reported some type of
it is considered that the psychotic phenotype is distributed subclinical experience. In this same work, in a sample of 4868
along a severity continuum, the clinical picture being located nonclinical adolescents, they analyzed two items from the
in most extensive part. In this sense, pseudo-psychotic Youth Self Report (YSR)23 that evaluated auditory and visual
symptoms could be considered as an “intermediate” variant hallucinatory phenomena. The results indicated that
or phenotype that is quantitatively less severe but approximately 11-12% of the sample contested affirming at
qualitatively similar to the symptoms seen in patients with least one item and that 5.2% stated they had experienced
schizophrenia, these occurring with less intensity, persistence, some hallucinatory phenomena.
frequency and associated discapacity.4-7
As occurs with schizophrenia, the phenotypal expression
Independent longitudinal studies performed in samples of these experiences on the subclinical level seems to vary
of the general population show that the presence of these based on gender and age.1, 2, 24, 25 Based on gender, adult
psychotiform signs at early ages increases the future risk of women generally report a greater number of positive
developing a disorder on the schizophrenic spectrum,8-11 and psychotic symptoms compared to adult males.24 In the same
also predicts the delusional experiences in the adult stage.12 way, adolescent women generally have more subclinical
For example, Poulton et al.,9 in a longitudinal study carried psychotic symptoms than the males.26, 27 However, both in
out in New Zealand in a sample of children, found that more the adult population28, 29 as well as in the adolescent one,
than 25% of the participants who reported these experiences results that do not indicate this association have been
at the age of 11 years developed a disorder of schizophreniform found.17, 19, 30 In relationship with age, younger participants
type at the age of 26 years. In the same way, as the temporal generally have higher scores in attenuated psychotic
persistence and frequency of these subclinical psychotic symptoms in comparison with older subjects,3, 27, 31 although
symptoms increase, the probability of evolving towards a works that only compare adolescent groups have not
clinical picture also increases.5, 13 The predictive value of confirmed these findings,17, 30 or have even found results to
these experiences is not only restricted to the studies the contrary.26
conducted in samples of the general population but also in
high-risk samples. In this sense, the presence of these Up to now in Spain, few empirical works have been
symptoms plays an important role in the subsequent carried out that attempt to analyze and understand the
transition towards disorders on the schizophrenic spectrum, phenotypal expression of subclinical psychotic symptoms in
both in first-degree family members of patients with the adolescent population. On the other hand, the role of
schizophrenia14 as well as in individuals with high clinical gender and age in the expression of these symptoms has also
risk.15, 16 These data suggest that attenuated psychotic not been clearly defined. Within this context of research, the
experiences could be considered as the behavioral expression principal objective of the present work was to examine the
of vulnerability to schizophrenic psychosis and its related presence of attenuated psychotic symptoms in a
disorders (e.g. schizoid, paranoid and schizotypal personality representative sample of adolescents from the general
disorders). population. Furthermore, the role played by gender and age
in the phenotypal expression of this type of pseudo-psychotic
Epidemiological studies conducted in the adult population experiences was also studied in greater depth. These
situated the mean prevalence of subclinical psychotic objectives are interesting since they make it possible to: a)
experiences at about 5%.3 In the adolescent population, improve the understanding of the attenuated psychotic
similar rates as those found in the adult population are found. symptoms, as markers of risk or vulnerability for
For example, Scott et al.,17 analyzing a sample of 1261 schizophrenia, without the compounding effects frequently
Australian adolescents, found that 8.4% of them reported found in patients (e.g. medication and stigmatization) and
having experienced some visual or auditory hallucinatory before the clinical expression of the disorder; b) the early
experience at some time. On his part, Horwood et al.,18 using a detection of individuals at risk for disorders on the
sample of 6455 English adolescents, found that 38.9% scored schizophrenic spectrum and the establishment of action
on more than one item regarding psychotic experiences. In lines within the early intervention programs in a period of
Spain, the interest in subclinical psychotic symptoms studies special risk for the development of the psychopathological
in the adolescent population has also increased. For example, picture as in adolescence; c) have empirical data available in
Obiols et al.,19 using the Community Assessment of Psychic the general Spanish population that can be used within the
Experiences (CAPE)20 in a sample of 777 adolescents, found psychoeducational programs (e.g., patients with schizophrenia
that 44.1% reported at least one quasi-psychotic symptom or at high clinical risk) in order to demystify the presence of
and 19.7% manifested 3 or more experiences of this type. On these symptoms only within the psychotic picture and d) go
his part, Fonseca-Pedrero et al.,21 using 10 items from the deeper into the dimensional models of psychoses within the
Cuestionario Oviedo para la Evaluación de la Esquizotipia paradigm of the psychopathology of development.
Table 1 Descriptive statistics than number of items answered positively by the participants
for the total score and the subscales selected from the ESQUIZO-Q
Ideas of Reference 5.93 (2.5) 6.13 (2.7) 5.70 (2.3) 139 (9.7) 41 (2.9) 10 (0.7)
Magical Thinking 7.31 (2.8) 7.10 (2.7) 7.40 (2.9) 194 (13.5) 49 (3.4) 13 (0.9)
Perceptual Experiences 9.83 (3.8) 9.96 (3.9) 9.72 (3.8) 221 (15.4) 76 (5.3) 21 (1.5)
Paranoid Ideation 7.72 (3.2) 7.94 (3.3) 7.46 (3.1) 166 (11.5) 55 (3.8) 50 (3.4)
Total Score 60.80 (9.5) 31.13 (9.8) 30.28 (9.3) 268 (18.6) 134 (9.3) 216 (15)
* It is considered that an item has been answered positively when scored 4 or 5 in the response options of the questionnaire
Distortion dimension of the ESQUIZO-Q are presented, Analysis of Variance (MANOVA) was performed, using gender
both in the total sample and separately for the men and and age as fixed factors and the subscales and total score of
women. Furthermore, the number of participants who the positive dimension of the ESQUIZO-Q as dependent
reported one, two or three or more pseudo-psychotic variables. Wilk’s λ value showed statistically significant
experiences in the total sample was collected. It was differences based on gender (Wilk’s λ = 0.978, p < 0.001),
considered that an adolescent responded positively to an but not based on age (Wilk’s λ = 0.992, p = 0.802). Males
item on the ESQUIZO-Q when he/she chose their 4 or 5 scores higher than women on the Ideas of Reference
response options. As can be observed, a considerable subscales (F = 8.535, p = 0.004) and Paranoid Ideation (F =
percentage of the participants, that is 43%, reported some 6.984, p = 0.004). In both cases, the estimations of size of
type of subclinical psychotic experience. Breaking this effect were irrelevant. No statistically significant interactions
percentage down, 18.6% of the adolescents responded were found between gender and age of the participants.
positively to one item, 9.3% to two, 6.1% to three and (Tables 2 and 3).
8.9% to more than four items. The number and percentage
of participants of the total sample who responded
affirmatively to each one of the 21 items on the ESQUIZO-Q DISCUSSION AND CONCLUSIONS
are shown in Table 2. As can be observed, from 1.9% to
8.4% of the adolescents manifested symptoms related with The principal objective of this work was to analyze the
ideas of reference (items 1 to 4); from 1.5 % to 6.7% prevalence of the attenuated psychotic symptoms in the
reported experiences related with magical thinking (items general adolescent population and examine the role played
5 to 9); from 1.5% to 11.5% manifested symptoms related by gender and age in the phenotypal expression of these
with paranoid ideation (items 10 to 14) and finally from experiences. The results indicate that 43% of the participants
1% to 8.8% of the adolescents reported symptoms related reported positively having experienced at least one
with unusual perceptual experiences (items 15 to 21). The attenuated psychotic symptom. The rates of subclinical
items that obtained a higher rate of affirmative responses experiences found in this work are slightly superior to those
were item 11 (Someone has sworn to get me) and item 19 found in previous investigations in community samples of
(I have such real thoughts that it seems as if someone is the general population,1-3 and quite similar to those found in
talking to me). The items that obtained a lower rate of other studies performed in nonclinical adolescents.17, 19, 21, 39
affirmative responses were item 18 (I feel as if someone However, it should be mentioned that rigorous comparison
was sending occult messages that only I could understand) with other investigations was hindered because of the
and item 9 (When something goes wrong for me it is characteristics of the sample and measurement instrument
because someone has put a curse on me). (Table 1). as well as by the definition per se of the concept “Attenuated
psychotic symptoms” or “subclinical” symptoms. For example,
recently van Os et al.3 conducted a meta-analysis, finding
Expression of attenuated psychotic symptoms that the mean rate of these experiences in the adult
based on gender and age population was approximately 5%. However, in studies with
adolescent populations, slightly different percentages were
After, the relationship of gender and age with subclinical found, ranging from 2.2% to 73.1%.21 Specifically, previous
psychotic symptoms was studied. To do so, a Multivariate works performed in Spain have found similar results to those
Table 3 Percentage of participants, based on age, who scored 4 or 5 on the items selected
from the ESQUIZO-Q
sectional nature of this research must not be overlooked, so relationship between these psychotiform experiences with
that it is not possible to establish cause -effect interferences. other biochemical, physiological, environmental, behavioral
In the fourth place, and no less important, these psychotic and psychosocial variables in order to predict the possible
experiences should always be understood and analyzed clinical picture. Finally, the development of programs for
within a bio-psychosocial model in which the interaction early detection and intervention within the national public
and combination of a wide diversity of variables are and private health systems is of great importance. These
considered. In this sense, as already mentioned, in order to should have the basic and priority objective of early
develop a severe mental disorder, the combination of prevention of schizophrenia and its related disorders, in
multiple factors (genetic, environmental, etc.) and the order to mitigate the possible impact that may be caused on
necessary presence of other psychopathological signs and the personal, familial and social level by this devastating
symptoms (social withdrawal, flattened affectivity, thinking psychological disorder.
problems, odd behavior, significant alteration of the social
and work life, etc.) is necessary.
ACKNOWLEDGMENTS
Future lines of investigation should continue to study
the role of subclinical psychotic symptoms in the prediction This investigation has been financed by the Ministerio
of schizophrenic spectrum disorders both in the general de Ciencia e Innovación de España (MICINN), by the Instituto
population and in the participants at risk and through the Carlos III, Centro de Investigación Biomédica en Red de Salud
combined use of different measurement instruments.42-44 Mental (CIBERSAM). References of the projects: BES 2006-
Furthermore, it is also interesting to determine the type of 12797, PSI 2008-06220 and PSI 2008-03934.
Annex Items and subscales making up the Positive dimension of the ESQUIZO-Q
1. I believe that what appears on the radio or television has a special significance for me, that my friends do not understand
2. I notice that certain things have a hidden significance that only I can understand
3. I believe that I can detect hidden messages on the television or radio
4. I have the rare sensation that the things that appear on the radio or television are especially aimed to me
5. My lucky charms can even make me pass an examination
6. I believe that there are people who can read the minds of others
7. The dreams I have are signs that something bad is going to occur
8. I believe that there are persons who can control the thoughts of others
9. When something goes wrong for me, it is because someone has put a curse on me
10. I believe that someone is plotting against me.
11. Someone has sworn to get me
12. People look at me with disdain
13. The others think I am a bad person
14. My classmates have it in for me
15. When I am alone at home, I have the sensation that someone is speaking to me
16. I hear voices that others cannot hear
17. When I am alone, I have the sensation that someone is whispering my name
18. I feel as if someone sends occult messages that only I can understand)
19. I have such real thoughts that it seems as if someone is talking to me
20. I have felt like my body was not under my control
21. I have heard sounds that I cannot distinguish whether they are coming from my head or from outside
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