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MPHR QQRM - Edited

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MPR135 Quantitative and Qualitative Research Method

The Theranos Case

The Theranos case is a cautionary tale about upholding ethical standards in research and

business practices.

Informed Consent: Theranos' CEO, Elizabeth Holmes, needed to obtain consent from

participants in her company's blood-testing study. She promised that the technology could

provide accurate and comprehensive blood test results with just a few drops of blood, but did

not disclose the actual methods used to obtain these results. Participants were not informed

about the limitations, such as the inability to detect certain diseases, risks like potential

misdiagnosis, and potential errors like false positives, associated with the testing. This

violation of informed consent principle is a serious breach of ethical standards.

Research Misconduct: Theranos engaged in research misconduct by falsifying data,

misrepresenting results, and manipulating studies to achieve desired outcomes. This

manipulation led to publications in reputable scientific journals, which perpetuated the myth

of the company's innovative technology.

Non-Maleficence: Theranos actions also violated the principle of non-maleficence, which

requires researchers to avoid causing harm to participants. The companies tests are often

inaccurate, misleading, or incomplete, potentially leading to delayed or inadequate treatment

for patients. This lack of transparency and accuracy caused unnecessary harm to patients and

compromised their health and well-being.


Transparency and Accountability: Research ethics require transparency and accountability

in all stages of research, from study design to data collection and analysis. The lack of

transparency at Theranos, including withholding information from regulators and the public,

raises concerns about the integrity of the research conducted by the company.

Privacy and Confidentiality: Researchers must protect the privacy and confidentiality of

research participants' data. Theranos's handling of patient data raised concerns about privacy

and confidentiality breaches, particularly if inaccurate results were shared without adequate

consent or protection.

The Theranos case underscores the critical importance of upholding research ethics principles

in medical research. It serves as a stark reminder that prioritizing profit over patient welfare

and compromising on ethical standards can have far-reaching and devastating consequences

for patients and the scientific community as a whole. This is not just a lesson, but a call to

action to ensure that such violations are not repeated.

Submitted By

Ashwin M B

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