Introduction To BioPhysics
Introduction To BioPhysics
PHY4091: Introductiontobiophysics
This course is designed mainly for final year B.Tech. students who are willing to think about the
biological systems at the Nano scale. Biophysics is the area where problems related to structure, dynamics
and functioning of biomolecules are addressed using physical methods, underlying theories and models.
The goal of this course is to present (or refresh) the necessary concepts of physics and biology as well as
map their application on a rapidly expanding interdisciplinary interface, combining biology, chemistry,
computer science, and physics. The course aims to balance the need for rigorous mathematical treatment
with the simplicity of presentation. Thus it is intended to train students in mathematical and physical
modeling of biological systems and the complex biological phenomena.
Prerequisite Courses:First year Physics course, and calculus-based physics, and a distant memory of
high school chemistry and biology will be advantageous.
Course Topics:
14
UNIT 1: Principles from the sciences
3.Physical kinetics
4.The molecular dance
5.Molecular forces in biological structures
1.Structure of Macromolecules
2.Enzyme catalysis
12
3.Biomechanics
4.Single molecule force spectroscopy techniques
14
2.Mystery of protein folding
References
Text Book:
1. Philip Nelson, Biological Physics, (WH Freeman New York, 2004)
Department of Physics The LNMIIT, Jaipur
Reference books:
2. Bruce Alberts et al., Molecular Biology of the Cell, (Garland, 2002).
3. Rodney Cotterill, Biophysics: An introduction, (John Wiley & Sons, LTD, 2002)
4. M. Schliwa, Molecular Motors, (Wiley).
5. M. Rubinstein and R. H. Colby, Polymer Physics, (Oxford University Press, 2004)
6. Lecture notes and various Journal papers (will provide before the class).
Evaluation Methods: