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Introduction To BioPhysics

IBP good course

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ARJUN SAXENA
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© © All Rights Reserved
Available Formats
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0% found this document useful (0 votes)
31 views

Introduction To BioPhysics

IBP good course

Uploaded by

ARJUN SAXENA
Copyright
© © All Rights Reserved
Available Formats
Download as PDF, TXT or read online on Scribd
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Department of Physics The LNMIIT, Jaipur

PHY4091: Introductiontobiophysics

Target audience: B.Tech. (Final year) Year: IV Semester: VII


Elective category: OE Credits: 3 Hours: 40

Course overview (100 words):

This course is designed mainly for final year B.Tech. students who are willing to think about the
biological systems at the Nano scale. Biophysics is the area where problems related to structure, dynamics
and functioning of biomolecules are addressed using physical methods, underlying theories and models.
The goal of this course is to present (or refresh) the necessary concepts of physics and biology as well as
map their application on a rapidly expanding interdisciplinary interface, combining biology, chemistry,
computer science, and physics. The course aims to balance the need for rigorous mathematical treatment
with the simplicity of presentation. Thus it is intended to train students in mathematical and physical
modeling of biological systems and the complex biological phenomena.

Prerequisite Courses:First year Physics course, and calculus-based physics, and a distant memory of
high school chemistry and biology will be advantageous.

Course Outcomes (COs):

By the end of the course, students will be able to :


CO1 use physical techniques to get inside the nanoworld of cells, tweak them in physical ways,
and measure the results quantitatively.
CO2 familiar with various analytical and experimental techniques and aware about various
biological systems and related complex phenomena.
CO3 appraise recent Nano scale advances in biophysics
CO4 recognize and evaluate the role of free energy, heat, entropy, temperature, and random
thermal motion in various biological processes.
CO5 understand how simplified physical model(s) can express the richness and complexity of
various biological systems and processes
CO6 learn about an interdisciplinary area like Biophysics and apply the knowledge in various
related fields.
Department of Physics The LNMIIT, Jaipur

Course Topics:

Topics Lecture Hours

14
UNIT 1: Principles from the sciences

1.Basic notions of thermodynamics

2.Basic notion of statistical mechanics

3.Physical kinetics
4.The molecular dance
5.Molecular forces in biological structures

UNIT 2: Molecules, Structures, and Mechanisms

1.Structure of Macromolecules
2.Enzyme catalysis
12
3.Biomechanics
4.Single molecule force spectroscopy techniques

UNIT 3: Complexity of biological systems and processes

1.Dynamics of molecular motors

14
2.Mystery of protein folding

3.Life in crowded and disordered environments


Total 40

References
Text Book:
1. Philip Nelson, Biological Physics, (WH Freeman New York, 2004)
Department of Physics The LNMIIT, Jaipur

Reference books:
2. Bruce Alberts et al., Molecular Biology of the Cell, (Garland, 2002).
3. Rodney Cotterill, Biophysics: An introduction, (John Wiley & Sons, LTD, 2002)
4. M. Schliwa, Molecular Motors, (Wiley).
5. M. Rubinstein and R. H. Colby, Polymer Physics, (Oxford University Press, 2004)
6. Lecture notes and various Journal papers (will provide before the class).

Evaluation Methods:

Items Weightage (%)


Quizzes 15
Midterm 25
Final Examination and Term paper
40 + 20

Prepared By: Dr. Ashok Garai


Last Update: 31st May 2018

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