SAFETY DATA SHEET Version 6.

5
Revision Date 02.06.2023
according to Regulation (EC) No. 1907/2006 Print Date 17.10.2024
GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1 Product identifiers
Product name : Sodium chloride
Product Number : S5886
Brand : Sigma
REACH No. : 01-2119485491-33-XXXX
CAS-No. : 7647-14-5

1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Chemie GmbH
Eschenstrasse 5
D-82024 TAUFKIRCHEN
Telephone : +49 (0)89 6513-1130
Fax : +49 (0)89 6513-1161
E-mail address : technischerservice@merckgroup.com
1.4 Emergency telephone
Emergency Phone # : 0800 181 7059 (CHEMTREC Deutschland)
+49 (0)696 43508409 (CHEMTREC
weltweit)

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture
Not a hazardous substance or mixture according to Regulation (EC) No 1272/2008.
2.2 Label elements
No hazard pictogram, no signal word, no hazard statement(s), no precautionary
statement(s) required

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2.3 Other hazards
This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at
levels of 0.1% or higher.

SECTION 3: Composition/information on ingredients

3.1 Substances
Formula : ClNa
Molecular weight : 58,44 g/mol
CAS-No. : 7647-14-5
EC-No. : 231-598-3
No components need to be disclosed according to the applicable regulations.

SECTION 4: First aid measures

4.1 Description of first-aid measures
If inhaled
After inhalation: fresh air.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with
water/ shower.
In case of eye contact
After eye contact: rinse out with plenty of water. Remove contact lenses.
If swallowed
After swallowing: make victim drink water (two glasses at most). Consult doctor if feeling
unwell.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section
2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available

SECTION 5: Firefighting measures

5.1 Extinguishing media
Suitable extinguishing media
Use extinguishing measures that are appropriate to local circumstances and the
surrounding environment.
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Hydrogen chloride gas
Sodium oxides
Not combustible.
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 Ambient fire may liberate hazardous vapours.
5.3 Advice for firefighters
In the event of fire, wear self-contained breathing apparatus.
5.4 Further information
Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire
extinguishing water from contaminating surface water or the ground water system.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Avoid inhalation of dusts. Evacuate the danger
area, observe emergency procedures, consult an expert.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions
(see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid
generation of dusts.
6.4 Reference to other sections
For disposal see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditions
Tightly closed. Dry.
Storage class
Storage class (TRGS 510): 13: Non Combustible Solids
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

8.1 Control parameters
Ingredients with workplace control parameters
8.2 Exposure controls
Personal protective equipment

Eye/face protection
Use equipment for eye protection tested and approved under appropriate
government standards such as NIOSH (US) or EN 166(EU). Safety glasses
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 Skin protection
This recommendation applies only to the product stated in the safety data sheet,
supplied by us and for the designated use. When dissolving in or mixing with other
substances and under conditions deviating from those stated in EN374 please
contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Material tested:KCL 741 Dermatril® L
This recommendation applies only to the product stated in the safety data sheet,
supplied by us and for the designated use. When dissolving in or mixing with other
substances and under conditions deviating from those stated in EN374 please
contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Material tested:KCL 741 Dermatril® L

Respiratory protection
required when dusts are generated.
Our recommendations on filtering respiratory protection are based on the following
standards: DIN EN 143, DIN 14387 and other accompanying standards relating to
the used respiratory protection system.
Recommended Filter type: Filter type P1
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory
protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Control of environmental exposure
Do not let product enter drains.

SECTION 9: Physical and chemical properties

9.1 Information on basic physical and chemical properties
a) Physical state powder
b) Color colorless
c) Odor odorless
d) Melting Melting point/range: 801 °C
point/freezing point
e) Initial boiling point 1.413 °C
and boiling range
f) Flammability (solid, The product is not flammable.
gas)

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 g) Upper/lower No data available
flammability or
explosive limits
h) Flash point Not applicable
i) Autoignition No data available
temperature
j) Decomposition 1.000 °C
temperature
k) pH 7
l) Viscosity Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
m) Water solubility 317 g/l at 20 °C - completely soluble
n) Partition coefficient: Not applicable for inorganic substances
n-octanol/water
o) Vapor pressure No data available
p) Density 2,16 g/cm3 at 25 °C
Relative density 2,16 at 25 °C
q) Relative vapor
density
r) Particle No data available
characteristics

s) Explosive properties No data available

t) Oxidizing properties none
9.2 Other safety information
Surface tension 73,03 mN/m at 14,5g/l at 23 °C

SECTION 10: Stability and reactivity

10.1 Reactivity
No data available
10.2 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
The product is chemically stable under standard ambient conditions (room temperature) .
10.3 Possibility of hazardous reactions
Risk of explosion/exothermic reaction with:
Alkali metals
Exothermic reaction with:
Lithium

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10.4 Conditions to avoid
no information available
10.5 Incompatible materials
No data available
10.6 Hazardous decomposition products
In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects
Acute toxicity
Oral: No data available
Inhalation: No data available
LD50 Dermal - Rabbit - > 10.000 mg/kg
Remarks: (RTECS)
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation
Remarks: (ECHA)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: No eye irritation
Remarks: (ECHA)
Respiratory or skin sensitization
No data available
Germ cell mutagenicity
Animal testing did not show any mutagenic effects.
Test Type: Ames test
Test system: Escherichia coli/Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Carcinogenicity
Did not show carcinogenic effects in animal experiments.
Reproductive toxicity
Did not show teratogenic effects in animal experiments.
No impairment of reproductive performance suspected.
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available

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11.2 Additional Information
Endocrine disrupting properties
Product:
Assessment : The substance/mixture does not contain
components considered to have endocrine
disrupting properties according to REACH Article
57(f) or Commission Delegated regulation (EU)
2017/2100 or Commission Regulation (EU)
2018/605 at levels of 0.1% or higher.
RTECS: VZ4725000
Vomiting, Diarrhea, Dehydration and congestion may occur in internal organs. Hypertonic
salt solutions can produce inflammatory reactions in the gastrointestinal tract., Nausea
To the best of our knowledge, the chemical, physical, and toxicological properties have not
been thoroughly investigated.

SECTION 12: Ecological information

12.1 Toxicity
Toxicity to fish flow-through test LC50 - Lepomis macrochirus (Bluegill) - 5.840 mg/l
- 96 h
Remarks: (ECHA)

Toxicity to daphnia static test EC50 - Daphnia magna (Water flea) - 874 mg/l - 48 h
and other aquatic Remarks: (ECHA)
invertebrates
static test LC50 - Daphnia magna (Water flea) - 4.136 mg/l - 48 h
(OECD Test Guideline 202)
Toxicity to algae static test EC50 - Nitzschia sp. - 2.430 mg/l - 120 h
(OECD Test Guideline 201)
Toxicity to flow-through test NOEC - Pimephales promelas (fathead minnow) -
fish(Chronic toxicity) 252 mg/l - 33 d
(OECD Test Guideline 210)
Toxicity to daphnia semi-static test NOEC - Daphnia pulex (Water flea) - 314 mg/l - 21
and other aquatic d
invertebrates(Chronic (OECD Test Guideline 211)
toxicity)
12.2 Persistence and degradability
The methods for determining the biological degradability are not applicable to inorganic
substances.
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment

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 This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at
levels of 0.1% or higher.
12.6 Endocrine disrupting properties
Product:
Assessment : The substance/mixture does not contain components
considered to have endocrine disrupting properties
according to REACH Article 57(f) or Commission
Delegated regulation (EU) 2017/2100 or Commission
Regulation (EU) 2018/605 at levels of 0.1% or higher.

12.7 Other adverse effects

Discharge into the environment must be avoided.

SECTION 13: Disposal considerations

13.1 Waste treatment methods
No data available

SECTION 14: Transport information

14.1 UN number
ADR/RID: - IMDG: - IATA: -
14.2 UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
14.3 Transport hazard class(es)
ADR/RID: - IMDG: - IATA: -
14.4 Packaging group
ADR/RID: - IMDG: - IATA: -
14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user
No data available
Further information
Not classified as dangerous in the meaning of transport regulations.

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations/legislation specific for the
substance or mixture
This material safety data sheet complies with the requirements of Regulation (EC) No.
1907/2006.
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15.2 Chemical Safety Assessment
For this product a chemical safety assessment was not carried out

SECTION 16: Other information

Full text of other abbreviations
ADN - European Agreement concerning the International Carriage of Dangerous Goods
by Inland Waterways; ADR - Agreement concerning the International Carriage of
Dangerous Goods by Road; AIIC - Australian Inventory of Industrial Chemicals; ASTM -
American Society for the Testing of Materials; bw - Body weight; CMR - Carcinogen,
Mutagen or Reproductive Toxicant; DIN - Standard of the German Institute for
Standardisation; DSL - Domestic Substances List (Canada); ECx - Concentration
associated with x% response; ELx - Loading rate associated with x% response; EmS -
Emergency Schedule; ENCS - Existing and New Chemical Substances (Japan); ErCx -
Concentration associated with x% growth rate response; GHS - Globally Harmonized
System; GLP - Good Laboratory Practice; IARC - International Agency for Research on
Cancer; IATA - International Air Transport Association; IBC - International Code for the
Construction and Equipment of Ships carrying Dangerous Chemicals in Bulk; IC50 - Half
maximal inhibitory concentration; ICAO - International Civil Aviation Organization;
IECSC - Inventory of Existing Chemical Substances in China; IMDG - International
Maritime Dangerous Goods; IMO - International Maritime Organization; ISHL - Industrial
Safety and Health Law (Japan); ISO - International Organisation for Standardization;
KECI - Korea Existing Chemicals Inventory; LC50 - Lethal Concentration to 50 % of a
test population; LD50 - Lethal Dose to 50% of a test population (Median Lethal Dose);
MARPOL - International Convention for the Prevention of Pollution from Ships; n.o.s. -
Not Otherwise Specified; NO(A)EC - No Observed (Adverse) Effect Concentration;
NO(A)EL - No Observed (Adverse) Effect Level; NOELR - No Observable Effect Loading
Rate; NZIoC - New Zealand Inventory of Chemicals; OECD - Organization for Economic
Co-operation and Development; OPPTS - Office of Chemical Safety and Pollution
Prevention; PBT - Persistent, Bioaccumulative and Toxic substance; PICCS - Philippines
Inventory of Chemicals and Chemical Substances; (Q)SAR - (Quantitative) Structure
Activity Relationship; REACH - Regulation (EC) No 1907/2006 of the European
Parliament and of the Council concerning the Registration, Evaluation, Authorisation and
Restriction of Chemicals; RID - Regulations concerning the International Carriage of
Dangerous Goods by Rail; SADT - Self-Accelerating Decomposition Temperature; SDS -
Safety Data Sheet; TCSI - Taiwan Chemical Substance Inventory; TECI - Thailand
Existing Chemicals Inventory; TSCA - Toxic Substances Control Act (United States); UN
- United Nations; UNRTDG - United Nations Recommendations on the Transport of
Dangerous Goods; vPvB - Very Persistent and Very Bioaccumulative

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 Further information
The above information is believed to be correct but does not purport to be all inclusive
and shall be used only as a guide. The information in this document is based on the
present state of our knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any guarantee of the properties of
the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any
damage resulting from handling or from contact with the above product. See
www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional
terms and conditions of sale.

Copyright 2020 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies
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